Name: Secluded cabin on private property
Address: De Soto

Your De Soto Vacation

Experience the unique character and personality of De Soto with a tailor-made De Soto vacation package. From its welcoming locals to its rich history, you'll never have a boring moment in this city. A trip to De Soto wouldn't be complete without visiting a few top attractions, starting with Victoria Glaces Conservation Area Trailhead. No matter your travel plans or budget, organizing a tailored De Soto vacation is a cinch with Expedia.

Top De Soto Vacation Deals

Price found within the past 48 hours. Click for updated prices.

Hilton Garden Inn Chesterfield

CA $1,021

per person

Oct 15 - Oct 20

found 1 day ago

Roundtrip non-stop flight included

Edmonton (YEG) to St. Louis (STL)

8.2/10 Very Good! (763 reviews)

I booked online and paid via the app. When I arrived on site they explained they had overbooked and had no rooms available. The staff was amazing and went above and beyond and secured a room at another location. Thank you to the staff for taking care of us.

Reviewed on Jul. 26, 2025

The Wildwood Hotel

CA $1,141

per person

Oct 15 - Oct 20

found 1 day ago

Roundtrip non-stop flight included

Edmonton (YEG) to St. Louis (STL)

9.2/10 Wonderful! (1,562 reviews)

Always comfortable, always convenient and reliable when I'm visiting the area. It's my go-to hotel in the area.

Reviewed on Aug. 25, 2025

White House at Grand Central

Grand Center

CA $1,097

per person

Oct 15 - Oct 20

found 1 day ago

Roundtrip non-stop flight included

Edmonton (YEG) to St. Louis (STL)

8.6/10 Excellent! (116 reviews)

It was very clean and nicely decorated. The house is a cool old building. The AC worked great (important, as it was super muggy outside.) I was only there for a couple nights but I think it would have worked well for a longer stay.

Reviewed on Jul. 9, 2025

DoubleTree by Hilton St. Louis Forest Park

Central West End

CA $1,220

per person

Oct 15 - Oct 20

found 1 day ago

Roundtrip non-stop flight included

Edmonton (YEG) to St. Louis (STL)

8.2/10 Very Good! (1,002 reviews)

Parking is terrible and you shouldn’t have to pay $15 to park then charge for breakfast when your paying all that money to stay!!

Reviewed on Aug. 23, 2025

Home2 Suites by Hilton St. Louis Downtown

Downtown West

CA $1,170

per person

Oct 15 - Oct 20

found 1 day ago

Roundtrip non-stop flight included

Edmonton (YEG) to St. Louis (STL)

8/10 Very Good! (498 reviews)

Loved the historical property and surrounding historical activities.

Reviewed on Aug. 23, 2025

Ready to book your vacation to De Soto?

Choose your dates

De Soto Hotel Deals

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

4800 U.S. Highway 67, De Soto, MO

Fully refundable

CA $192

CA $224 total

Sep 7 - Sep 8

includes taxes & fees

9.4/10 Exceptional! (150 reviews)

Family weekend

"My family and I enjoyed our relaxing weekend. The resort was pretty full but you wouldnt know it. Nothing we did was crowded. The pool and area around it was beautiful. The water crystal clear. The villa was quiet and clean."

Reviewed on Aug. 25, 2025

Pool, Lake & Patio: Sweeping De Soto Estate

De Soto

10/10 Exceptional! (1 review)

"I do not want to gate keep this property. It was beyond our expectations. All I could do was gasp at every turn I made. The host was very helpful, professional, with great communication. Everything was exceptionally clean which sometimes can be iffy with rentals, not this one. You can tell it is ..."

Reviewed on Aug. 11, 2025

Get rates

Secluded cabin on private property

De Soto

Get rates

See all 170 properties in De Soto

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.