Charleston Vacation Rentals

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Our top choices for Charleston vacation rentals

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (27 reviews)
"The place was quiet, clean and secluded. Exactly what my wife and I were looking for. Thanks for having us!"
United States
Andy I.
The price is CA $173
CA $274 total
includes taxes & fees
Jun 9 - Jun 10
Peaceful secluded cabin located near Horseshoe Lake

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is CA $167
CA $401 total
includes taxes & fees
Jun 4 - Jun 5
Quiet Country Stay: Modern Home Near Paducah

The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (31 reviews)
"It’s very nice and comfortable "
United States
John S.
The price is CA $156
CA $194 total
includes taxes & fees
Jun 8 - Jun 9
The Rested Duck Mallard Room

Charming Home just minutes from Interstate and Mall

Charming Home just minutes from Interstate and Mall
Kevil
10.0 out of 10, Exceptional, (23 reviews)
"Comfortable couch and recliner, abundant space, great shower head, hosts were phenomenal! It was perfect for our needs. "
United States
Lance N.
The price is CA $152
CA $261 total
includes taxes & fees
Jun 4 - Jun 5
Charming Home just minutes from Interstate and Mall

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (57 reviews)
"Great cute place. "
United States
Jeremy W.
The price is CA $112
CA $150 total
includes taxes & fees
Jun 7 - Jun 8
Little Blue Cottage on Spanish

Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (41 reviews)
"Peaceful and suited our needs perfectly."
United States
Matthew
The price is CA $156
CA $194 total
includes taxes & fees
Jun 9 - Jun 10
Cozy cabins on beautiful Horseshoe Lake

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
Cunningham
10.0 out of 10, Exceptional, (2 reviews)
"Host was great. "
United States
Sheila C.
The price is CA $149
CA $405 total
includes taxes & fees
Jun 4 - Jun 5
Quiet Country Stay: Modern Home Near Paducah

Vacation rental attached to our house out in the country.

Vacation rental attached to our house out in the country.
Union City
10.0 out of 10, Exceptional, (4 reviews)
"The home was spotless, very comfortable and a great location for what we needed."
United States
Sherrie S.
The price is CA $138
CA $224 total
includes taxes & fees
Jun 7 - Jun 8
Vacation rental attached to our house out in the country.

Tranquil charming Tiny House in Clinton

Tranquil charming Tiny House in Clinton
Clinton
10.0 out of 10, Exceptional, (2 reviews)
"It is clean and comfortable. Would definitely stay again if ever in the area."
United States
Jennifer M.
The price is CA $143
CA $227 total
includes taxes & fees
Jun 8 - Jun 9
Tranquil charming Tiny House in Clinton

Modern Boho Getaway · 1BR Apartment · By KeenStays

Modern Boho Getaway · 1BR Apartment · By KeenStays
Cape Girardeau
The price is CA $111
CA $231 total
includes taxes & fees
Jun 4 - Jun 5
Modern Boho Getaway · 1BR Apartment · By KeenStays

Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space
Cape Girardeau
10.0 out of 10, Exceptional, (157 reviews)
"Nice location to river front and downtown. Very lovely place."
United States
Marcie R.
The price is CA $208
CA $341 total
includes taxes & fees
Jun 4 - Jun 5
Serenity South -- Gardens, River-Views, and Refreshing Space

Studio Apt | King Bed, Full Kitchen · By KeenStays

Studio Apt | King Bed, Full Kitchen · By KeenStays
Cape Girardeau
The price is CA $111
CA $231 total
includes taxes & fees
Jun 16 - Jun 17
Studio Apt | King Bed, Full Kitchen · By KeenStays

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (40 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is CA $323
CA $526 total
includes taxes & fees
Jun 14 - Jun 15
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid
10.0 out of 10, Exceptional, (1 review)
"The host was very quick to respond and so great to work with for on our stay. "
United States
Jessica S.
The price is CA $277
CA $505 total
includes taxes & fees
Jun 4 - Jun 5
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.6 out of 10, Exceptional, (9 reviews)
"Nice place, great times"
United States
Jace W.
The price is CA $524
CA $837 total
includes taxes & fees
Jun 14 - Jun 15
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Charleston Hotel Reviews

Find out more about Charleston

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Charleston. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in Charleston?

Yes, we have vacation rentals close to the most popular sights in Charleston, or you can go with a secluded option if you want a relaxing place to stay. Our travelers say Charleston has a good selection of restaurants. Make sure you have time to check out the entertainment choices and theaters during your trip.

What are some of the best vacation rentals that Charleston has to offer?

Serenity South -- Gardens, River-Views, and Refreshing Space: Visitors like this Charleston vacation home rental. It is located on a river and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games.

What can I see and do in Charleston?

Mississippi River and Ohio River are a couple of lovely local spots to get outside and enjoy nature. Columbus-Belmont State Park and Central Park are a couple of places you'll find in the larger area.

What are vacation rentals like in Charleston?

Vacation rentals are private accommodations you can book for a few days or a quick weekend in Charleston. Vacation rentals feature extras like WiFi and washers and dryers so you'll feel just like you're at home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from shared hotel elevators and bustling concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental a great choice for family trips.