Hotels in Downtown, Seneca

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Our top choices for Downtown hotels

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (708 reviews)
"Clean room comfortable beds"
United States
Cheryl
The price is CA $117
CA $137 total
includes taxes & fees
Jun 5 - Jun 6
Quality Inn Seneca Clemson Area US-123

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
25 km from Downtown
9.2 out of 10, Wonderful, (622 reviews)
"Room was clean and customer service was excellent, check in was smooth "
United States
Gina
The price is CA $147
CA $163 total
includes taxes & fees
Jul 3 - Jul 4
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
2 km from Downtown
9.4 out of 10, Exceptional, (234 reviews)
"Excellent in every way … staff, room, amenities and very comfortable bed!"
United States
Sarah
The price is CA $178
CA $196 total
includes taxes & fees
Jun 23 - Jun 24
Fairfield Inn & Suites Seneca Clemson Univ Area

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
15.2 km from Downtown
9.8 out of 10, Exceptional, (856 reviews)
"Terrific place to stay and the staff was very helpful too."
United States
Anne
The price is CA $206
CA $228 total
includes taxes & fees
Jun 9 - Jun 10
The Inn at Patrick Square

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
11.8 km from Downtown
8.2 out of 10, Very good, (1,009 reviews)
"We always stay here when in Clemson. It's convenient and the breakfast and restaurant are great."
United States
Greg
The price is CA $152
CA $168 total
includes taxes & fees
Jun 29 - Jun 30
Best Western Plus Clemson Hotel & Conference Center

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
3.1 km from Downtown
6.8 out of 10, (752 reviews)
"Clean and comfortable "
United States
Robyn
The price is CA $100
CA $110 total
includes taxes & fees
Jun 18 - Jun 19
Days Inn by Wyndham Seneca / Clemson Area

Hampton Inn & Suites Lavonia

Hampton Inn & Suites Lavonia
2.5 star property
30.7 km from Downtown
9.0 out of 10, Wonderful, (407 reviews)
"The breakfast was great, the staff was very friendly and the hotel very clean. We highly recommend."
United States
Russell
The price is CA $186
CA $221 total
includes taxes & fees
Jun 17 - Jun 18
Hampton Inn & Suites Lavonia

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
10.6 km from Downtown
9.8 out of 10, Exceptional, (806 reviews)
"Great location great restaurant"
United States
Jennifer
The price is CA $189
CA $210 total
includes taxes & fees
Jun 16 - Jun 17
The Shepherd Hotel Downtown Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
24.8 km from Downtown
8.4 out of 10, Very good, (1,004 reviews)
"Wonderful staff very helpful"
United States
atlantis
The price is CA $112
CA $124 total
includes taxes & fees
Jun 19 - Jun 20
Microtel Inn & Suites by Wyndham Anderson/Clemson

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
10.1 km from Downtown
9.6 out of 10, Exceptional, (602 reviews)
"Easy parking, great location. Will stay there again"
United States
William
The price is CA $184
CA $204 total
includes taxes & fees
Jul 1 - Jul 2
The Abernathy of Clemson

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
10.3 km from Downtown
9.4 out of 10, Exceptional, (1,000 reviews)
"Lovely place to stay right on the lake. "
United States
Sara
The price is CA $165
CA $183 total
includes taxes & fees
Jun 3 - Jun 4
Clemson University's James F. Martin Inn

Budget Inn Express

Budget Inn Express
2.0 star property
19.9 km from Downtown
5.8 out of 10, (252 reviews)
"Facilities and entertainment surround the Hotel in short trips!"
United States
Stephen
The price is CA $90
CA $100 total
includes taxes & fees
Jun 3 - Jun 4
Budget Inn Express

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
25.7 km from Downtown
9.0 out of 10, Wonderful, (728 reviews)
"Had a nice stay bed was comfortable and room was clean."
United States
Jon
The price is CA $137
CA $152 total
includes taxes & fees
Jun 15 - Jun 16
Hilton Garden Inn Anderson

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
11.7 km from Downtown
8.4 out of 10, Very good, (1,004 reviews)
"Great breakfast and friendly staff made our stay enjoyable."
United States
Lon
The price is CA $148
CA $165 total
includes taxes & fees
Jun 10 - Jun 11
Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
8.6 km from Downtown
9.0 out of 10, Wonderful, (1,003 reviews)
"Beautiful property and nice room."
United States
Lynzee
The price is CA $150
CA $187 total
includes taxes & fees
Jun 15 - Jun 16
Lakeside Lodge Clemson

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
25.6 km from Downtown
8.0 out of 10, Very good, (1,005 reviews)
"Everything about the place was great"
United States
Eli
The price is CA $85
CA $94 total
includes taxes & fees
Jun 22 - Jun 23
Days Inn by Wyndham Anderson

Hampton Inn Anderson

Hampton Inn Anderson
2.5 star property
25 km from Downtown
8.8 out of 10, Excellent, (416 reviews)
"Convenient location and friendly front desk staff"
United States
Mark
The price is CA $157
CA $174 total
includes taxes & fees
Jun 19 - Jun 20
Hampton Inn Anderson

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
8.4 km from Downtown
9.2 out of 10, Wonderful, (845 reviews)
"Everything about this hotel was great the staff was very friendly rooms was very clean great location I highly suggest staying here"
United States
Jason
The price is CA $153
CA $168 total
includes taxes & fees
Jun 16 - Jun 17
Tru by Hilton Seneca Clemson

Holiday Inn Express Hotel & Suites Lavonia by IHG

Holiday Inn Express Hotel & Suites Lavonia by IHG
2.5 star property
30.7 km from Downtown
8.8 out of 10, Excellent, (420 reviews)
"Great place ro stay"
United States
Ida
The price is CA $181
CA $215 total
includes taxes & fees
Jun 28 - Jun 29
Holiday Inn Express Hotel & Suites Lavonia by IHG

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson
2.5 star property
25 km from Downtown
7.0 out of 10, Good, (887 reviews)
"It was peaceful with lots of food options around. Room was clean and the beds were comfortable."
United States
Emely
The price is CA $88
CA $98 total
includes taxes & fees
Jun 15 - Jun 16
Baymont by Wyndham Anderson Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown

Find the best Downtown areas and neighborhoods for the activities you enjoy most. Learn more about Downtown
Learn more about Downtown

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and World of Energy are some notable places to visit nearby.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like The Gauntlet and Seneca Historic District.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to The Gauntlet and Seneca Historic District, some noteworthy sights in the nearby area.

Top Downtown Hotel Reviews

Frequently asked questions

What is Downtown like?
Travelers to the Downtown neighborhood in Seneca will be sure to enjoy their stay. Be sure to check out Seneca Historic District and The Gauntlet as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
Based on our traveler data, Quality Inn Seneca Clemson Area US-123 is one of the top choices for your stay in Downtown. This hotel offers free breakfast and free parking.
How many hotels can I expect to find in Downtown?
If you're searching for places to stay in Seneca, choose from one of Expedia's 13 hotels and other accommodations in Downtown.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best deals in Downtown.
What can I see and do in this Seneca neighborhood?
Seneca Historic District, The Gauntlet, and Blue Ridge Arts Center are just a few attractions to check out in Downtown. As you're discovering the neighborhood, Bertha Lee Strickland Cultural Museum and Oconee County Library Seneca Branch are some other places worth a visit. Seneca City Hall, Golden Corner Plaza, and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, be sure to visit other sights like Applewood Shopping Center or Wyndham Plaza.