Hotels in Downtown, Seneca

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Downtown hotels

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (679 reviews)
"Everting was good"
United States
Susan
The price is CA $106
CA $125 total
includes taxes & fees
Feb 25 - Feb 26
Quality Inn Seneca Clemson Area US-123

Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
12.8 km from Downtown
7.6 out of 10, Good, (175 reviews)
"Older hotel with great staff. It was safe and provided a great place for a stop over on the way to TN. I would definitely stay here again. "
United States
Laura
The price is CA $93
CA $103 total
includes taxes & fees
Mar 20 - Mar 21
Rodeway Inn & Suites Walhalla

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
7.5 km from Downtown
9.8 out of 10, Exceptional, (60 reviews)
"Excellent stay."
United States
Beonca
The price is CA $94
CA $164 total
includes taxes & fees
Feb 25 - Feb 26
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
4.0 star property
16.3 km from Downtown
10.0 out of 10, Exceptional, (79 reviews)
"The owners are amazing. Comfy rooms, stellar breakfast and good people. "
United States
Renee
Liberty Hall Bed and Breakfast

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
11.8 km from Downtown
8.2 out of 10, Very good, (1,002 reviews)
"Our room was very clean and the staff were very nice and courteous!"
United States
Tina
The price is CA $125
CA $139 total
includes taxes & fees
Feb 23 - Feb 24
Best Western Plus Clemson Hotel & Conference Center

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
15.2 km from Downtown
9.8 out of 10, Exceptional, (799 reviews)
"Clean room, great location, wonderful staff!"
United States
Joyce
The price is CA $203
CA $226 total
includes taxes & fees
Feb 23 - Feb 24
The Inn at Patrick Square

Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
3.5 star property
12.5 km from Downtown
7.0 out of 10, Good, (202 reviews)
"Clean room"
United States
Claudia
The price is CA $115
CA $128 total
includes taxes & fees
Feb 22 - Feb 23
Days Inn by Wyndham Clemson

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
25.7 km from Downtown
9.0 out of 10, Wonderful, (700 reviews)
"Rooms were clean, staff were friendly, and we had 2 good night’s sleep."
United States
Sadie
The price is CA $135
CA $150 total
includes taxes & fees
Mar 1 - Mar 2
Hilton Garden Inn Anderson

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
2 km from Downtown
9.4 out of 10, Exceptional, (207 reviews)
"Spotless, friendly staff, great location. "
United States
Cari
The price is CA $170
CA $188 total
includes taxes & fees
Feb 22 - Feb 23
Fairfield Inn & Suites Seneca Clemson Univ Area

Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
12.7 km from Downtown
9.8 out of 10, Exceptional, (9 reviews)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
The price is CA $121
CA $324 total
includes taxes & fees
Feb 22 - Feb 23
Clemson Memorabilia House

Woodspring Suites Anderson North I-85

Woodspring Suites Anderson North I-85
2.5 star property
25.4 km from Downtown
7.8 out of 10, Good, (84 reviews)
"Cleanliness, staff was very nice, decent price"
United States
Carolyn
The price is CA $101
CA $112 total
includes taxes & fees
Feb 26 - Feb 27
Woodspring Suites Anderson North I-85

Americas Best Value Inn Anderson, SC

Americas Best Value Inn Anderson, SC
2.0 star property
27.9 km from Downtown
6.0 out of 10, (156 reviews)
"Nice little motel with friendly owners. Beds were a little too firm and breakfast a bit lacking, but for the price, it was fine. We enjoyed our stay. "
United States
Heather
The price is CA $94
CA $104 total
includes taxes & fees
Feb 20 - Feb 21
Americas Best Value Inn Anderson, SC

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
8.6 km from Downtown
9.0 out of 10, Wonderful, (1,005 reviews)
"Great place and location, great mattress, "
United States
Jeffrey
The price is CA $149
CA $185 total
includes taxes & fees
Mar 1 - Mar 2
Lakeside Lodge Clemson

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
8.4 km from Downtown
9.2 out of 10, Wonderful, (810 reviews)
"Perfect stay for a weekend. Lots of shopping and restaurants nearby. Clean safe area annd the staff was wonderful!"
United States
Cindy
The price is CA $148
CA $163 total
includes taxes & fees
Mar 15 - Mar 16
Tru by Hilton Seneca Clemson

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
29.6 km from Downtown
7.0 out of 10, Good, (896 reviews)
"Bueno was "
Mexico
Alejandro
The price is CA $76
CA $84 total
includes taxes & fees
Mar 15 - Mar 16
Quality Inn Clemson near University

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson
2.5 star property
25 km from Downtown
7.0 out of 10, Good, (856 reviews)
"Well lit parking and safe area around the hotel"
United States
Gregory
The price is CA $75
CA $84 total
includes taxes & fees
Mar 1 - Mar 2
Baymont by Wyndham Anderson Clemson

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
25.6 km from Downtown
7.8 out of 10, Good, (1,005 reviews)
"The room was spotless, the property well kept, the staff was kind and helpful and the location was great! "
United States
Kayla
The price is CA $86
CA $95 total
includes taxes & fees
Mar 1 - Mar 2
Days Inn by Wyndham Anderson

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
1.7 km from Downtown
8.4 out of 10, Very good, (650 reviews)
"The stay was amazing "
United States
Tabatha
The price is CA $126
CA $139 total
includes taxes & fees
Feb 25 - Feb 26
Best Western Seneca-Clemson

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
10.3 km from Downtown
9.4 out of 10, Exceptional, (973 reviews)
"Everything was very nice "
United States
Paige
The price is CA $203
CA $226 total
includes taxes & fees
Mar 1 - Mar 2
Clemson University's James F. Martin Inn

Inn @ Clemson

Inn @ Clemson
2.5 star property
11.6 km from Downtown
8.2 out of 10, Very good, (1,004 reviews)
"Staff and hotel was amazing "
United States
Keren
Inn @ Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown

Find the best Downtown areas and neighborhoods for the activities you enjoy most. Learn more about Downtown
Learn more about Downtown

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and Keowee Key Golf Course are some notable places to visit nearby.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like The Gauntlet and Seneca City Hall.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to The Gauntlet and Seneca City Hall, some noteworthy sights in the nearby area.

Top Downtown Hotel Reviews

Frequently asked questions

What is Downtown like?
Travelers to the Downtown neighborhood in Seneca will be sure to enjoy their stay. Be sure to check out Oconee County Library Seneca Branch and The Gauntlet as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
Based on Expedia customer reviews, Quality Inn Seneca Clemson Area US-123 is the highest ranked property in Downtown. This hotel offers free breakfast and free parking.
How many hotels can I expect to find in Downtown?
Expedia has 9 Downtown hotels and other accommodations, and one might make a good home base for venturing out into the greater Seneca area.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best deals in Downtown.
What can I see and do in this Seneca neighborhood?
Oconee County Library Seneca Branch, The Gauntlet, and Seneca City Hall are just a few attractions to check out in Downtown. As you're discovering the neighborhood, Seneca Historic District and Bertha Lee Strickland Cultural Museum are some other places worth a visit. Golden Corner Plaza, Oconee Community Theatre, and Applewood Shopping Center are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, be sure to visit other sights like Wyndham Plaza or Cross Creek Plantation Golf.