Downtown
Seneca
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Stay near popular Downtown attractions
Downtown Hotel Deals
Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
The price is CA $112 per night from Aug 30 to Aug 31
CA $112
CA $137 total
Aug 30 - Aug 31
includes taxes & fees
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Historic Seneca Bungalow
Seneca SC
Stay at this vacation home in Seneca. Enjoy a garden, laundry facilities, and an in-room coffeemaker. Popular attractions Memorial Stadium and Walnut Street ...
9.8/10 Exceptional! (28 reviews)
"We really enjoyed our stay."
Reviewed on Jul 23, 2026
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
The price is CA $148 per night from Aug 19 to Aug 20
CA $148
CA $164 total
Aug 19 - Aug 20
includes taxes & fees
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
The price is CA $256 per night from Aug 2 to Aug 3
CA $256
CA $285 total
Aug 2 - Aug 3
includes taxes & fees
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.8/10 Exceptional! (857 reviews)
"First time here. Fantastic. Heart of downtown Clemson, walk to campus. Amenities were excellent and staff was extremely helpful and knowledgeable."
Reviewed on Jul 30, 2026
Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
The price is CA $153 per night from Aug 3 to Aug 4
CA $153
CA $190 total
Aug 3 - Aug 4
includes taxes & fees
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
The price is CA $85 per night from Aug 16 to Aug 17
CA $85
CA $94 total
Aug 16 - Aug 17
includes taxes & fees
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Downtown
Find the best Downtown areas and neighborhoods for the activities you enjoy most. Learn more about Downtown
Learn more about Downtown
Serenity Bay
Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.
Pine Ridge Point
While Pine Ridge Point isn't home to many top sights, South Beach and Lake Keowee are some notable places to visit nearby.
Indian Oaks
While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Oconee County Library Seneca Branch and Keowee Reservoir.
Keowee Plantation
When in Keowee Plantation, you can plan a visit to Keowee Reservoir and Oconee County Library Seneca Branch, some noteworthy sights in the nearby area.
Downtown
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