Boat Ride on Lake Hartwell

Hotels in Downtown, Seneca

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Check prices for these dates

Next weekend
Jun 19 - Jun 21
In two weeks
Jun 26 - Jun 28

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Our top choices for Downtown hotels

Free daily on-the-go breakfast

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (713 reviews)
"Clean room comfortable beds"
United States
Cheryl
The price is CA $118
CA $139 total
includes taxes & fees
Jun 21 - Jun 22
Quality Inn Seneca Clemson Area US-123
Property amenity

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
2 km from Downtown
9.4 out of 10, Exceptional, (235 reviews)
"Excellent in every way … staff, room, amenities and very comfortable bed!"
United States
Sarah
The price is CA $168
CA $185 total
includes taxes & fees
Jun 18 - Jun 19
Fairfield Inn & Suites Seneca Clemson Univ Area
Hallway

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
15.2 km from Downtown
9.8 out of 10, Exceptional, (863 reviews)
"Terrific place to stay and the staff was very helpful too."
United States
Anne
The price is CA $208
CA $231 total
includes taxes & fees
Jun 15 - Jun 16
The Inn at Patrick Square
Hallway

Hampton Inn & Suites Lavonia

Hampton Inn & Suites Lavonia
2.5 star property
30.7 km from Downtown
9.0 out of 10, Wonderful, (408 reviews)
"The breakfast was great, the staff was very friendly and the hotel very clean. We highly recommend."
United States
Russell
The price is CA $190
CA $225 total
includes taxes & fees
Jun 21 - Jun 22
Hampton Inn & Suites Lavonia
Property amenity

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
25 km from Downtown
9.2 out of 10, Wonderful, (624 reviews)
"Room was clean and customer service was excellent, check in was smooth "
United States
Gina
The price is CA $154
CA $171 total
includes taxes & fees
Jun 19 - Jun 20
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Free breakfast

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
11.8 km from Downtown
8.2 out of 10, Very good, (1,005 reviews)
"We always stay here when in Clemson. It's convenient and the breakfast and restaurant are great."
United States
Greg
The price is CA $133
CA $148 total
includes taxes & fees
Jun 17 - Jun 18
Best Western Plus Clemson Hotel & Conference Center
Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Bathroom

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
11.7 km from Downtown
8.4 out of 10, Very good, (1,005 reviews)
"Great breakfast and friendly staff made our stay enjoyable."
United States
Lon
The price is CA $153
CA $170 total
includes taxes & fees
Jul 8 - Jul 9
Comfort Inn & Suites Clemson - University Area
Free daily on-the-go breakfast

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
3.1 km from Downtown
6.8 out of 10, (753 reviews)
"Clean and comfortable "
United States
Robyn
The price is CA $106
CA $116 total
includes taxes & fees
Jun 30 - Jul 1
Days Inn by Wyndham Seneca / Clemson Area
Lobby

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
25.7 km from Downtown
9.0 out of 10, Wonderful, (734 reviews)
"Great place to stay"
United States
Maureen
The price is CA $139
CA $154 total
includes taxes & fees
Jun 20 - Jun 21
Hilton Garden Inn Anderson
Aerial view

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
8.6 km from Downtown
9.0 out of 10, Wonderful, (1,014 reviews)
"I enjoyed my stay and all the amenities were excellent! I can’t wait to return!"
United States
Renata
The price is CA $152
CA $189 total
includes taxes & fees
Jun 15 - Jun 16
Lakeside Lodge Clemson
Desk, soundproofing, iron/ironing board, free WiFi

Budget Inn Express

Budget Inn Express
2.0 star property
19.9 km from Downtown
5.8 out of 10, (252 reviews)
"Facilities and entertainment surround the Hotel in short trips!"
United States
Stephen
The price is CA $92
CA $102 total
includes taxes & fees
Jun 15 - Jun 16
Budget Inn Express
Golf

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
10.3 km from Downtown
9.4 out of 10, Exceptional, (1,005 reviews)
"This was such a great hotel! The staff were so nice and friendly, the hotel and room were clean and comfy. I would definitely stay again and recommend to others. "
United States
Melissa
The price is CA $194
CA $216 total
includes taxes & fees
Jul 1 - Jul 2
Clemson University's James F. Martin Inn
Lobby lounge

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
10.1 km from Downtown
9.6 out of 10, Exceptional, (611 reviews)
"Great location - wonderful hotel!"
United States
Samuel
The price is CA $169
CA $187 total
includes taxes & fees
Jul 1 - Jul 2
The Abernathy of Clemson
Snack bar

Hampton Inn Anderson

Hampton Inn Anderson
2.5 star property
25 km from Downtown
8.8 out of 10, Excellent, (419 reviews)
"The room did have a funny smell at first, but overall it was clean. The two ladies at the desk was AMAZING. Definitely will book again"
United States
Bernadette
The price is CA $159
CA $176 total
includes taxes & fees
Jun 21 - Jun 22
Hampton Inn Anderson
Lobby

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
29.6 km from Downtown
7.0 out of 10, Good, (940 reviews)
"Clean room,ac in the middle of a decent size town, overall good hotel"
United States
Roberto
The price is CA $80
CA $88 total
includes taxes & fees
Jul 5 - Jul 6
Quality Inn Clemson near University
Standard Room, 1 King Bed, Non Smoking, Jetted Tub

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
1.7 km from Downtown
8.4 out of 10, Very good, (664 reviews)
"Friendly staff, comfortable bed"
United States
Michelle
The price is CA $136
CA $149 total
includes taxes & fees
Jun 16 - Jun 17
Best Western Seneca-Clemson
Lobby

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
10.6 km from Downtown
9.8 out of 10, Exceptional, (816 reviews)
"Great place to stay"
United States
Amy
The price is CA $198
CA $220 total
includes taxes & fees
Jun 16 - Jun 17
The Shepherd Hotel Downtown Clemson
Studio Suite, 1 King Bed, Non Smoking | Jetted tub

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
25.6 km from Downtown
8.0 out of 10, Very good, (1,017 reviews)
"Everything about the place was great"
United States
Eli
The price is CA $82
CA $91 total
includes taxes & fees
Jun 22 - Jun 23
Days Inn by Wyndham Anderson
Indoor pool

Holiday Inn Express Hotel & Suites Lavonia by IHG

Holiday Inn Express Hotel & Suites Lavonia by IHG
2.5 star property
30.7 km from Downtown
8.8 out of 10, Excellent, (421 reviews)
"Very friendly staff. Room was clean and breakfast was good!"
United States
Rebecca
The price is CA $178
CA $211 total
includes taxes & fees
Jun 28 - Jun 29
Holiday Inn Express Hotel & Suites Lavonia by IHG
Lobby

Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC
2.5 star property
25.2 km from Downtown
8.4 out of 10, Very good, (1,009 reviews)
"Room was very clean and the staff super friendly. Kids got to use the pool and great breakfast before checking out. Wonderful stay!"
United States
Makayla
The price is CA $150
CA $166 total
includes taxes & fees
Jun 21 - Jun 22
Country Inn & Suites by Radisson, Anderson, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown

Find the best Downtown areas and neighborhoods for the activities you enjoy most. Learn more about Downtown
Learn more about Downtown

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.
Female Kayaker on Lake Keowee at Sunset

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and Keowee Key Golf Course are some notable places to visit nearby.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like The Gauntlet and Seneca Historic District.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to The Gauntlet and Seneca Historic District, some noteworthy sights in the nearby area.

Top Downtown Hotel Reviews

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

6/10 Okay
"The room was clean… but very musky smelling. Not like the pictures. Okay for the price."
Catherine 1-night trip
Posted 10 hours ago
Days Inn by Wyndham Anderson

Frequently asked questions

What is Downtown like?
Travelers to the Downtown neighborhood in Seneca will be sure to enjoy their stay. Be sure to check out The Gauntlet and Seneca Historic District as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
Based on our traveler data, Quality Inn Seneca Clemson Area US-123 is one of the top choices for your stay in Downtown. This hotel offers free breakfast and free parking.
How many hotels can I expect to find in Downtown?
If you're searching for places to stay in Seneca, choose from one of Expedia's 13 hotels and other accommodations in Downtown.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best deals in Downtown.
What can I see and do in this Seneca neighborhood?
The Gauntlet, Seneca Historic District, and Blue Ridge Arts Center are just a few attractions to check out in Downtown. As you're discovering the neighborhood, Bertha Lee Strickland Cultural Museum and Oconee County Library Seneca Branch are some other places worth a visit. Seneca City Hall, Golden Corner Plaza, and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, be sure to visit other sights like Applewood Shopping Center or Wyndham Plaza.