Title: Byron Vacation Rentals from CA $163: Short-Term Rentals for 2026 | Expedia.ca

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## Check prices for these dates

In two weeks

[Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2026-02-27&endDate=2026-03-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 8 - May 10](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 5 - Jun 7](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Byron vacation rentals

![Interior](https://images.trvl-media.com/lodging/89000000/88140000/88134300/88134280/b289cba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/89000000/88140000/88134300/88134280/w504h639x260y44-1bc74fd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/89000000/88140000/88134300/88134280/w904h683x60y0-9d597388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/89000000/88140000/88134300/88134280/w904h683x60y0-3cf0fc10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Valley Cabin

[](https://www.expedia.ca/Spring-Valley-Hotels-Valley-Cabin.h88134280.Hotel-Information)

Spring Valley

9.2/10

Wonderful

(7 reviews)

"Great property with plenty of outdoor activities. Had fun fishing the stream and exploring the area. Dan is a great host and I will be visiting again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

JAKE I.

CA $74

CA $172 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Spring-Valley-Hotels-Valley-Cabin.h88134280.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/113000000/112840000/112838900/112838810/db2bcbab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fireplace](https://images.trvl-media.com/lodging/113000000/112840000/112838900/112838810/9aad035e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/113000000/112840000/112838900/112838810/b2be6c45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/113000000/112840000/112838900/112838810/f49e01b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

[](https://www.expedia.ca/Rochester-Hotels-Discounted-Charming-2-Bedroom-House-In-Rochester.h112838810.Hotel-Information)

East Side Pioneers

8.8/10

Excellent

(13 reviews)

"Great stay for a quick stop in Rochester. Clean, quiet neighborhood."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jill S.

CA $67

CA $234 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Rochester-Hotels-Discounted-Charming-2-Bedroom-House-In-Rochester.h112838810.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/52000000/51270000/51267300/51267208/90-3e521435.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/52000000/51270000/51267300/51267208/90-3a8a456d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/52000000/51270000/51267300/51267208/0cc41438.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/52000000/51270000/51267300/51267208/18c8f73f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Magical Nest Hideaway

[](https://www.expedia.ca/Rochester-Hotels-Magical-Nest-Hideaway.h51267208.Hotel-Information)

Rochester

10/10

Exceptional

(139 reviews)

"Great place to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Matthew S.

CA $80

CA $163 total

includes taxes & fees

Feb 25 - Feb 26

[](https://www.expedia.ca/Rochester-Hotels-Magical-Nest-Hideaway.h51267208.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101430000/101428100/101428059/10e83a4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/102000000/101430000/101428100/101428059/63c8ec1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/102000000/101430000/101428100/101428059/da041c63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/102000000/101430000/101428100/101428059/d4ef1ad3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!

[](https://www.expedia.ca/Rochester-Hotels-2-Bedroom-Oasis-5-Minutes-To-Mayo-Clinic.h101428059.Hotel-Information)

Rochester

9.6/10

Exceptional

(26 reviews)

"Convenient location for staying during Mayo Clinic procedure. The host was great and the place was comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stephanie M.

CA $61

CA $238 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Rochester-Hotels-2-Bedroom-Oasis-5-Minutes-To-Mayo-Clinic.h101428059.Hotel-Information)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/125000000/124060000/124057100/124057034/24fc6695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/125000000/124060000/124057100/124057034/175a96c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/125000000/124060000/124057100/124057034/383c165b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/125000000/124060000/124057100/124057034/f17efbd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Viola Suite #1 / 1 bed, 1.5 Bath, Pets Welcome!

[](https://www.expedia.ca/Rochester-Hotels-Viola-Suite-1-1-Bed.h124057034.Hotel-Information)

Rochester

CA $63

CA $214 total

includes taxes & fees

Feb 19 - Feb 20

[](https://www.expedia.ca/Rochester-Hotels-Viola-Suite-1-1-Bed.h124057034.Hotel-Information)

![Smart TV, DVD player, books, video library](https://images.trvl-media.com/lodging/125000000/124580000/124571800/124571748/e692ce86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/125000000/124580000/124571800/124571748/67d8872b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/125000000/124580000/124571800/124571748/34b22830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/125000000/124580000/124571800/124571748/79d965e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 2.5 miles to Mayo, 4 step entry Covered By Faith

[](https://www.expedia.ca/Rochester-Hotels-25-Miles-To-Mayo.h124571748.Hotel-Information)

Rochester

CA $116

CA $339 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Rochester-Hotels-25-Miles-To-Mayo.h124571748.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/123000000/122670000/122668000/122667923/a6a0e908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122670000/122668000/122667923/3e543e44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/123000000/122670000/122668000/122667923/15722e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122670000/122668000/122667923/9da21b22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Delightful cabin with AC in Racine

[](https://www.expedia.ca/Racine-Hotels-Delightful-Cabin-With-AC-In-Racine.h122667923.Hotel-Information)

Racine

CA $170

CA $212 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Racine-Hotels-Delightful-Cabin-With-AC-In-Racine.h122667923.Hotel-Information)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/120000000/119760000/119751900/119751899/bde39aeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119760000/119751900/119751899/11aaf550.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/120000000/119760000/119751900/119751899/4a112a03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/120000000/119760000/119751900/119751899/d062e60d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester

[](https://www.expedia.ca/Rochester-Hotels-Meet-Don-A-Modern.h119751899.Hotel-Information)

Slatterly Park

10/10

Exceptional

(14 reviews)

"Everything was wonderful. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Danielle V.

CA $246

CA $320 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Rochester-Hotels-Meet-Don-A-Modern.h119751899.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/103000000/102820000/102818100/102818074/79facf0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102820000/102818100/102818074/cca7001b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, travel crib, free WiFi](https://images.trvl-media.com/lodging/103000000/102820000/102818100/102818074/1686d319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102820000/102818100/102818074/f67ae586.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Color House // 2 Bed, 2 Ba, 1 mi to Mayo Clinic, No Stairs to Entry

[](https://www.expedia.ca/Rochester-Hotels-The-Color-House-2-Bed.h102818074.Hotel-Information)

East Side Pioneers

9.4/10

Exceptional

(13 reviews)

"Great place!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeremiah E.

CA $149

CA $356 total

includes taxes & fees

Feb 19 - Feb 20

[](https://www.expedia.ca/Rochester-Hotels-The-Color-House-2-Bed.h102818074.Hotel-Information)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/94000000/93800000/93793600/93793571/a0150ca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/94000000/93800000/93793600/93793571/afca5be6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/94000000/93800000/93793600/93793571/59ed3cd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/94000000/93800000/93793600/93793571/551ab46d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

[](https://www.expedia.ca/Rochester-Hotels-Discounted-Oasis-5-Star-3-Bedroom-Showstopping-Duplex-4-Minutes-To-Mayo-Clinic.h93793571.Hotel-Information)

East Side Pioneers

9.0/10

Wonderful

(25 reviews)

"Great location , close to Mayo clinic as needed. Owner addressed the shower head issue immediately, great communication. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Barb W.

CA $90

CA $312 total

includes taxes & fees

Feb 24 - Feb 25

[](https://www.expedia.ca/Rochester-Hotels-Discounted-Oasis-5-Star-3-Bedroom-Showstopping-Duplex-4-Minutes-To-Mayo-Clinic.h93793571.Hotel-Information)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/103000000/102170000/102161300/102161201/d5eba066.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/103000000/102170000/102161300/102161201/b900a374.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102170000/102161300/102161201/e6f79fb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102170000/102161300/102161201/4d110927.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The June // A one bedroom basement apartment, 3 mi to Mayo Clinic

[](https://www.expedia.ca/Rochester-Hotels-The-June-A-One-Bedroom-Basement-Apartment.h102161201.Hotel-Information)

Rochester

10/10

Exceptional

(5 reviews)

"This place was quiet, comfortable, well-stocked, and incredibly close to everything we were looking for. The hosts were great communicators, and accessing the place was a snap."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Josh P.

CA $91

CA $262 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Rochester-Hotels-The-June-A-One-Bedroom-Basement-Apartment.h102161201.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/101000000/100200000/100194400/100194373/dc05b783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100200000/100194400/100194373/c7575fb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/101000000/100200000/100194400/100194373/083347ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/101000000/100200000/100194400/100194373/a6c285de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 2 bedroom apartment in downtown Zumbrota. Sleeps 4-6.

[](https://www.expedia.ca/Zumbrota-Hotels-2-Bedroom-Apartment-In-Downtown-Zumbrota-Sleeps-4-6.h100194373.Hotel-Information)

Zumbrota

10/10

Exceptional

(61 reviews)

"Great spot!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Levi S.

CA $150

CA $190 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Zumbrota-Hotels-2-Bedroom-Apartment-In-Downtown-Zumbrota-Sleeps-4-6.h100194373.Hotel-Information)

![Smart TV, DVD player, foosball, books](https://images.trvl-media.com/lodging/110000000/109800000/109794700/109794606/e16768bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/110000000/109800000/109794700/109794606/1b2234b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/110000000/109800000/109794700/109794606/8c1ae4fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/110000000/109800000/109794700/109794606/4bfcab60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 2 step entry 1 mile to Mayo CoveredByFaith Inspire

[](https://www.expedia.ca/Rochester-Hotels-2-Step-Entry-1-Mile-To-Mayo-Inspire-CoveredByFaith.h109794606.Hotel-Information)

Parkway

CA $87

CA $302 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Rochester-Hotels-2-Step-Entry-1-Mile-To-Mayo-Inspire-CoveredByFaith.h109794606.Hotel-Information)

![Smart TV, books](https://images.trvl-media.com/lodging/119000000/118970000/118966800/118966768/d46138d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/119000000/118970000/118966800/118966768/ac92f8ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118970000/118966800/118966768/e02d244f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/119000000/118970000/118966800/118966768/f588a75c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester

[](https://www.expedia.ca/Rochester-Hotels-Meet-Bev.h118966768.Hotel-Information)

Washington

9.8/10

Exceptional

(20 reviews)

"Great stay. Convenient to hospital. Very homey and comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer M.

CA $204

CA $268 total

includes taxes & fees

Feb 21 - Feb 22

[](https://www.expedia.ca/Rochester-Hotels-Meet-Bev.h118966768.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499051/aa49983d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499051/9764857b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, DVD player, offices](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499051/1c72d53e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499051/5086ed6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### King Suite Close to Mayo Clinic! Free Breakfast. Pool & Hot Tub.

[](https://www.expedia.ca/Rochester-Hotels-King-Suite-Close-To-Mayo-Clinic-Free-Breakfast-Pool-Hot-Tub.h56499051.Hotel-Information)

Rochester

10/10

Exceptional

(1 review)

"Good hotel with plenty of space to spread out. Great location with coffee and dining across the street. Easy to find and easy access to highways. Will stay here again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael F.

CA $149

CA $203 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Rochester-Hotels-King-Suite-Close-To-Mayo-Clinic-Free-Breakfast-Pool-Hot-Tub.h56499051.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/112000000/111290000/111284700/111284608/26025d59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111290000/111284700/111284608/c22c98da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111290000/111284700/111284608/c10914f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111290000/111284700/111284608/48fb1f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 2-bedroom apartment in delightful Rochester with WiFi, AC

[](https://www.expedia.ca/Rochester-Hotels-Charming-2-Bedroom-Apartment-In-Delightful-Rochester-With-WiFi.h111284608.Hotel-Information)

Meadow Park

10/10

Exceptional

(1 review)

"Quiet, clean and in a friendly neighborhood. Staying there took some of the stress out of my Mayo Clinic visits. I always worry about my follow-up visits, but a good quiet place to stay helps me let that go."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maria L E.

CA $129

CA $274 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Rochester-Hotels-Charming-2-Bedroom-Apartment-In-Delightful-Rochester-With-WiFi.h111284608.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499019/13771477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499019/364d4839.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, DVD player, offices](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499019/a2350e8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499019/1cb15748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Studio Suite! Free Breakfast + Shared Pool & Hot Tub. Great for Business Travelers!

[](https://www.expedia.ca/Rochester-Hotels-Studio-Suite-Free-Breakfast-Shared-Pool-Hot-Tub-Great-For-Business-Travelers.h56499019.Hotel-Information)

Rochester

8.6/10

Excellent

(4 reviews)

"Very nice and convenient stay. Everything we needed and extremely well maintained room and kitchen. Loved it and the responsiveness out our hosts!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rick H.

CA $147

CA $201 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Rochester-Hotels-Studio-Suite-Free-Breakfast-Shared-Pool-Hot-Tub-Great-For-Business-Travelers.h56499019.Hotel-Information)

![Smart TV, books](https://images.trvl-media.com/lodging/72000000/71370000/71363500/71363416/6246ff2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, travel crib, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71370000/71363500/71363416/3effdd9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/72000000/71370000/71363500/71363416/9c7af335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/72000000/71370000/71363500/71363416/6c81e0ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Little House // Stylish & Cozy \~ 2 mi from Mayo Clinic

[](https://www.expedia.ca/Rochester-Hotels-Stylish-Cozy-2-Mi-From-Mayo-Clinic.h71363416.Hotel-Information)

Slatterly Park

10/10

Exceptional

(19 reviews)

"I love staying in their properties. I always know I am going to be comfortable and have a great stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carissa W.

CA $137

CA $315 total

includes taxes & fees

Mar 3 - Mar 4

[](https://www.expedia.ca/Rochester-Hotels-Stylish-Cozy-2-Mi-From-Mayo-Clinic.h71363416.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/102000000/101170000/101161700/101161628/c10ebe66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101170000/101161700/101161628/18f935fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/102000000/101170000/101161700/101161628/62dcfb31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/102000000/101170000/101161700/101161628/d02f4f1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!

[](https://www.expedia.ca/Rochester-Hotels-5-Star-Restful-Haven-5-Minutes-To-Mayo-Clinic.h101161628.Hotel-Information)

Rochester

10/10

Exceptional

(9 reviews)

"It was amazing stay, it was very comfy, welcoming and definitely something we would book again!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jessica Z.

CA $109

CA $337 total

includes taxes & fees

Mar 1 - Mar 2

[](https://www.expedia.ca/Rochester-Hotels-5-Star-Restful-Haven-5-Minutes-To-Mayo-Clinic.h101161628.Hotel-Information)

![TV](https://images.trvl-media.com/lodging/121000000/120310000/120301200/120301196/6684d731.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120310000/120301200/120301196/8f7e9217.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop](https://images.trvl-media.com/lodging/121000000/120310000/120301200/120301196/w4080h2674x0y46-b002b895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/121000000/120310000/120301200/120301196/0d491749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Little Nest // 2 mi to Mayo Clinic, 2 bed w/Lg Yard,Pet Friendly,One level home

[](https://www.expedia.ca/Rochester-Hotels-Little-Nest-2-Mi-To-Mayo-Clinic.h120301196.Hotel-Information)

Rochester

CA $132

CA $389 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Rochester-Hotels-Little-Nest-2-Mi-To-Mayo-Clinic.h120301196.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Find vacation rentals that suit your style

Aparthotels

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Private vacation homes

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Apartments

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Cottages

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Cabins

[](https://www.expedia.ca/Hotel-Search?destination=Byron%2C+Minnesota%2C+United+States+of+America&regionId=553248623858895563&latLong=44.032742%2C-92.645462&adults=2&startDate=2026-05-14&d1=2026-05-14&endDate=2026-05-17&d2=2026-05-17&lodging=CABIN)

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## Top Byron Hotel Reviews

![EVEN Hotel Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg)

### EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Friendly atmosphere & great service in the lobby restaurant/bar"

[](https://expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information)

![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg)

### Kahler Grand Hotel

10/10 Excellent

"Great place to stay. Clean rooms. Awesome views. Easy to get to everywhere mayo clinic n everything u could possibly need while there. "

[](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information)

![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg)

### AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent

"Staff, able to eat to the bar and grill connecting to the motel "

[](https://expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information)

![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658_y.jpg)

### Aspen Suites

10/10 Excellent

"Room are very nice. Parking a bit tight and limited. Nice breakfast. They provide a quick meal at supper."

[](https://expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information)

![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg)

### Hampton Inn Rochester-South

10/10 Excellent

"We stayed here last year and both days have been wonderful. Staff is so friendly and helpful, pool area clean and"

[](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information)

![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg)

### Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"Comfy beds, relatively quiet, great amenities, restaurant/bar is excellent as well. Always stay there when I have to stay in Rochester."

[](https://expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information)

![Home2 Suites by Hilton Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/444e106b_y.jpg)

### Home2 Suites by Hilton Rochester Mayo Clinic Area

10/10 Excellent

"Always nice"

[](https://expedia.ca/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information)

![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg)

### Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"The room was clean the staff was friendly and the breakfast was very good. We are all ready planning to go back. "

[](https://expedia.ca/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information)

![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg)

### Spark by Hilton Rochester South

10/10 Excellent

"Clean room, modern, friendly staff. "

[](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information)

## Find out more about Byron

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Byron. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

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- [Québec Vacation Rentals ](https://www.expedia.ca/Quebec-Vacation-Rentals.d180017.Travel-Guide-VacationRentals)

- [Vacation Homes in Byron ](https://expedia.ca/Byron-Private-Vacation-Homes.d553248623858895563-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Apartments in Byron ](https://expedia.ca/Byron-Apartments.d553248623858895563-aaApartments.Travel-Guide-Accommodation)
- [Condo Rentals in Byron ](https://expedia.ca/Byron-Condos.d553248623858895563-aaCondos.Travel-Guide-Accommodation)
- [Cottages in Byron ](https://expedia.ca/Byron-Cottages.d553248623858895563-aaCottages.Travel-Guide-Accommodation)
- [Motels in Byron ](https://expedia.ca/Byron-Motels.d553248623858895563-aaMotels.Travel-Guide-Accommodation)
- [Cabin Rentals in Byron ](https://expedia.ca/Byron-Cabins.d553248623858895563-aaCabins.Travel-Guide-Accommodation)
- [Farmstay in Byron ](https://expedia.ca/Byron-Agritourism.d553248623858895563-aaAgritourism.Travel-Guide-Accommodation)
- [Aparthotels in Byron ](https://expedia.ca/Byron-Apart-Hotels.d553248623858895563-aaApartHotels.Travel-Guide-Accommodation)
- [B&B in Byron ](https://expedia.ca/Byron-Bed-And-Breakfast.d553248623858895563-aaBedAndBreakfast.Travel-Guide-Accommodation)

## Frequently asked questions

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