Title: Antofagasta Region Vacations & Trips 2026 from CA $416 | Expedia.ca [Antofagasta Region Travel Guide](https://expedia.ca/Antofagasta-Region.dx6236581)[Antofagasta Region Hotels](https://expedia.ca/Destinations-In-Antofagasta-Region.d6236581.Hotel-Destinations)[Vacation Rentals in Antofagasta Region](https://expedia.ca/Destinations-In-Antofagasta-Region.d6236581.Vacation-Rental-Destinations)[Antofagasta Region Car Rentals](https://expedia.ca/Destinations-In-Antofagasta-Region.d6236581.Car-Rental-Destinations) ![](https://images.trvl-media.com/place/6236581/9414dc4e-7e44-41c7-94b4-9f4e29cb4210.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Antofagasta Region Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Top vacation destinations in Antofagasta Region ![San Pedro de Atacama as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/121000/121139-San-Pedro-De-Atacama.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### San Pedro de Atacama [](https://expedia.ca/San-Pedro-De-Atacama.d500224.Destination-Travel-Guides) ![Antofagasta](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/121000/121662-Chile.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Antofagasta [](https://expedia.ca/Antofagasta.d382.Destination-Travel-Guides) ![El Tatio Geyser Field which includes a pond, tranquil scenes and animals](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/121000/121414-El-Tatio-Geyser-Field.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Calama [](https://expedia.ca/Calama.d847.Destination-Travel-Guides) ## Top Antofagasta Region Vacation Deals Price found within the past 48 hours. Click for updated prices. ![Hotel Modular Express Calama](https://images.trvl-media.com/lodging/27000000/26890000/26889600/26889569/f0e2b1a8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Modular Express Calama CA $416 per person Mar 14 - Mar 19 found 15 hours ago Roundtrip flight included Santiago (SCL) to Calama (CJC) 8/10 Very Good! (58 reviews) Really nice overall but a bit noisy outside Reviewed on Mar 8, 2025 ![Hotel Agua del Desierto](https://images.trvl-media.com/lodging/2000000/1520000/1514900/1514888/eb90013b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Agua del Desierto CA $793 per person Mar 14 - Mar 19 found 15 hours ago Roundtrip flight included Santiago (SCL) to Calama (CJC) 8.8/10 Excellent! (82 reviews) Very helpful staff and ideal for a night stop before catching a plane to Santiago. Good restaurant and excellent wines. Managers were very good. Reviewed on Feb 8, 2026 ![Atacama Lodge Rukazen](https://images.trvl-media.com/lodging/109000000/108930000/108923200/108923175/779755e7_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Atacama Lodge Rukazen CA $489 per person Mar 14 - Mar 19 found 15 hours ago Roundtrip flight included Santiago (SCL) to Calama (CJC) 9.8/10 Exceptional! (18 reviews) Ivan and Aracely were so welcoming and provided a spectacular service. For 2 days Ivan took us for several tour around the area and He was Very knowledgeable and safe driver. Reviewed on Dec 17, 2025 ![Sol del Desierto](https://images.trvl-media.com/lodging/23000000/22840000/22834000/22833978/70033101_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Sol del Desierto CA $695 per person Mar 14 - Mar 19 found 15 hours ago Roundtrip flight included Santiago (SCL) to Calama (CJC) 9.4/10 Exceptional! (9 reviews) A great little stay, its very quiet, secluded and very cozy Reviewed on May 19, 2025 ![Pat'ta Hoiri Hotel](https://images.trvl-media.com/lodging/10000000/9440000/9430500/9430423/b818fe77_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Pat'ta Hoiri Hotel CA $647 per person Mar 14 - Mar 19 found 15 hours ago Roundtrip flight included Santiago (SCL) to Calama (CJC) 8.4/10 Very Good! (74 reviews) We stayed for 5 nights and the staff were very kind and friendly. We had an issue with our toilet and Johnny got it fixed on the same day. The hotel was conveniently located, right next to a grocery shop, walking distance from the centre for restaurants and tours, and had secure parking which was a must for us. Breakfast was yummy too with a selection of cereal, bread, fruit, ham, cheese and eggs. Reviewed on Apr 16, 2025 ## Antofagasta Region Hotel Deals ![Diego de Almagro San Pedro de Atacama](https://images.trvl-media.com/lodging/2000000/1110000/1100500/1100408/ae70d540_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Diego de Almagro San Pedro de Atacama Toconao 460 San Pedro de Atacama Antofagasta Fully refundableReserve now, pay when you stay CA $163 CA $163 total Mar 1 - Mar 2 8/10 Very Good! (345 reviews) Convenient, pool was great but only open 12 to 8pm. 10000 for a towel .Breakfast buffet was good. Some areas are a little bit ran down. All in all its pretty nice. Reviewed on Jan 15, 2026 [](https://expedia.ca/Hotel-Search?startDate=01%2F03%2F2026&endDate=02%2F03%2F2026&selected=1100408&PinnedHotelID=1100408&HadPinnedHotel=true®ionId=6236581) ![Don Raúl](https://images.trvl-media.com/lodging/5000000/4440000/4432100/4432013/e8e67f4f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Don Raúl Calle Caracoles 130 San Pedro de Atacama El Loa CA $198 CA $198 total Feb 18 - Feb 19 8.2/10 Very Good! (194 reviews) We love the hotel, excellent staff, very friendly and extremely clean. Loved it! From Canada Reviewed on Dec 4, 2025 [](https://expedia.ca/Hotel-Search?startDate=18%2F02%2F2026&endDate=19%2F02%2F2026&selected=4432013&PinnedHotelID=4432013&HadPinnedHotel=true®ionId=6236581) ![Noi Casa Atacama](https://images.trvl-media.com/lodging/5000000/4250000/4248400/4248302/6a1fd8ff_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Noi Casa Atacama Tocopilla E-8 San Pedro de Atacama Antofagasta CA $375 CA $375 total Feb 19 - Feb 20 8.6/10 Excellent! (249 reviews) We had a very good stay. They are very accommodating and efficient. Location is good, close enough to the main st but far enough from the noises. Only thing is there’s no AC which might be typical for the region. They give you a fan which solves the issue. Overall, it’s very good . Reviewed on Dec 28, 2025 [](https://expedia.ca/Hotel-Search?startDate=19%2F02%2F2026&endDate=20%2F02%2F2026&selected=4248302&PinnedHotelID=4248302&HadPinnedHotel=true®ionId=6236581) [See all 300 properties in Antofagasta Region](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=11%2F02%2F2026&endDate=12%2F02%2F2026®ionId=6236581) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Frequently asked questions ### How much does an Antofagasta Region vacation package cost? ### How do I get a cheap travel package to Antofagasta Region? ### What are the top hotels in Antofagasta Region? ### How far in advance should I book my Antofagasta Region vacation? ### What does an Expedia Antofagasta Region travel package include? ### What should I know before booking an Antofagasta Region travel package? ### Can I choose my airline with an Antofagasta Region Expedia vacation package? ### If I'm not able to travel, can I cancel my Antofagasta Region vacation package? ### Discover the most popular places to visit in Antofagasta Region ![Valle de la Luna featuring desert views](https://images.trvl-media.com/place/6098516/dcc47ea9-6e77-4a74-b4ab-c885b853b18c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Valley of the Moon 5/5(14 reviews) Treat your eyes to the variety of colors in a deserted valley that looks like a scene from a science fiction movie. [](https://expedia.ca/Valley-Of-The-Moon-San-Pedro-de-Atacama.d6098516.Vacation-Attraction) #### Plaza de San Pedro de Atacama 4/5(13 reviews) You can find out about the history of San Pedro de Atacama when you stop by Plaza de San Pedro de Atacama. You can seek out the local tours in this quaint area. [](https://expedia.ca/Plaza-De-San-Pedro-De-Atacama-San-Pedro-de-Atacama.d6098510.Vacation-Attraction) #### Piedra del Coyote Overlook 4/5(1 review) Explore the great outdoors at Piedra del Coyote Overlook, a lovely green space in San Pedro de Atacama. You can seek out the local tours in this quaint area. [](https://expedia.ca/Piedra-Del-Coyote-Overlook-San-Pedro-de-Atacama.d6314541.Vacation-Attraction) ### What to do in Antofagasta Region ![San Pedro de Atacama: Stargazing Experience with Transfer](https://mediaim.expedia.com/localexpert/48194324/ffbc2e78-0a1d-4cdd-9146-23bcdd47e560.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### San Pedro de Atacama: Stargazing Experience CA $55 per adult [](https://expedia.ca/things-to-do/san-pedro-de-atacama-stargazing-experience.a48194324.activity-details) ![Tour to the Valley of the Moon in San Pedro de Atacama](https://mediaim.expedia.com/localexpert/5267485/f8da0e62-e07f-4a96-954f-d071cc484db9.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Tour to the Valley of the Moon San Pedro de Atacama CA $48 per adult **94%** of travellers recommend [](https://expedia.ca/things-to-do/tour-to-the-valley-of-the-moon-san-pedro-de-atacama.a5267485.activity-details) ![San Pedro de Atacama: Etno-Stargazing Tour with Transfer](https://mediaim.expedia.com/localexpert/4762165/18928608-7bef-4803-9b02-e7791f355ff7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### San Pedro de Atacama: Etno-Stargazing Tour with Transfer CA $56 per adult [](https://expedia.ca/things-to-do/san-pedro-de-atacama-etno-stargazing-tour-with-transfer.a4762165.activity-details) [See all activities in Antofagasta Region](https://expedia.ca/things-to-do/search?rid=6236581) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app