Title: 5 Stars Hotels in Mesopotamia, Argentina from CA $107 - Find Cheap Mesopotamia Hotels With 5 Stars | Expedia.ca [Mesopotamia Travel Guide](https://expedia.ca/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.ca/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d6208836.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d6208836.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.ca/Mesopotamia.d6208836.Destination-Travel-Guides) ![Mesopotamia showing a river or creek and forests](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/196000/196544-Mesopotamia.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 5 Stars Hotels in Mesopotamia, Argentina from CA $107 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mesopotamia 5 Star Hotels Tonight [Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-16&endDate=2025-10-17&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 17 - Oct 18](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-17&endDate=2025-10-18&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6208836&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mesopotamia 5 Star Hotels ![Lobby](https://images.trvl-media.com/lodging/5000000/4390000/4388000/4387932/5e4f0852.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4390000/4388000/4387932/39aab7b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/5000000/4390000/4388000/4387932/9efdb0ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4390000/4388000/4387932/05a55ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bagú Urbano Posadas 8.4/10 Very good (342) "Nice hotel in deplorable maintenance conditions. Dirtiest carpets and couches I've ever seen. Carpets in the hallways and within the bedrooms had deep stains all throughout. Our mattress and bedsheets had stains on them as well. It's really a pity because the property has potential, but evidently the decision has been made to not invest a dime in maintaining it." [](https://www.expedia.ca/Posadas-Hotels-Hotel-Urbano-Posadas.h4387932.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mesopotamia-Hotels.s50-0-d6208836.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mesopotamia-Hotels.s50-0-d6208836.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mesopotamia. ![Esplendor by Wyndham Savoy Rosario](https://images.trvl-media.com/lodging/3000000/2810000/2803500/2803473/36b8ac51_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Esplendor by Wyndham Savoy Rosario San Lorenzo 1022, Between Sarmiento and San Martín, Rosario, Santa Fe CA $110 CA $110 total Oct 19 - Oct 20 8.4/10 Very Good! (439 reviews) [](https://expedia.ca/Rosario-Hotels-Esplendor-By-Wyndham-Savoy-Rosario.h2803473.Hotel-Information) ![Dazzler by Wyndham Rosario](https://images.trvl-media.com/lodging/21000000/20270000/20265400/20265319/65a9aa22_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Dazzler by Wyndham Rosario Junin 187, Rosario, Santa Fe CA $107 CA $107 total Oct 19 - Oct 20 8.6/10 Excellent! (181 reviews) [](https://expedia.ca/Rosario-Hotels-Dazzler-By-Wyndham-Rosario.h20265319.Hotel-Information) ![InterTower Hotel](https://images.trvl-media.com/lodging/10000000/9850000/9845300/9845278/13fc6ccf_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### InterTower Hotel San Jeronimo 2779, Santa Fe, Santa Fe CA $142 CA $142 total Oct 19 - Oct 20 8.8/10 Excellent! (205 reviews) [](https://expedia.ca/Santa-Fe-Hotels-InterTower-Hotel.h9845278.Hotel-Information) Still don't see what you're looking for? [See all properties in Mesopotamia.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F10%2F2025&endDate=18%2F10%2F2025®ionId=6208836&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F10%2F2025&endDate=18%2F10%2F2025®ionId=6208836&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F10%2F2025&endDate=18%2F10%2F2025®ionId=6208836&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F10%2F2025&endDate=18%2F10%2F2025®ionId=6208836&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F10%2F2025&endDate=18%2F10%2F2025®ionId=6208836&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F10%2F2025&endDate=18%2F10%2F2025®ionId=6208836&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Mesopotamia The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration. [See all hotels in Mesopotamia](https://www.expedia.ca/Hotel-Search?startDate=2025-10-30&endDate=2025-10-31&adults=2®ionId=6208836) ![Mesopotamia showing a river or creek and forests](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/196000/196544-Mesopotamia.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Mesopotamia Hotel Reviews ## Find out more about Mesopotamia Luxury is the name of the game at the best 5 Stars hotels in Mesopotamia. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Mesopotamia 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them. Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Mesopotamia hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Mesopotamia without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Mesopotamia. ## Explore a world of travel with Expedia - More ways to book - [Book 5 Star Hotels in Mesopotamia on Expedia.com.ar](https://www.expedia.com.ar/5Estrella-Mesopotamia-Hoteles.s50-0-d6208836.Guia-filtrada-de-Hoteles)