Find hotels near Twilight Epiphany Skyspace, Houston from CA $150

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Our top choices for Twilight Epiphany Skyspace hotels

A modern building with multiple floors, large windows, and outdoor seating area with chairs and tables.

1. Hotel Saint Augustine

Hotel Saint Augustine
3.5 star property
Montrose, 2.1 km from Twilight Epiphany Skyspace
9.6 out of 10, Exceptional, (190 reviews)
"Perfect stay from check-in to check-out. Would absolutely stay here again!"
United States
Jacqueline
The price is CA $419
CA $494 total
includes taxes & fees
Nov 29 - Nov 30
Hotel Saint Augustine
A modern hotel building with a prominent entrance, large windows, and a visible name sign.

2. InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
Texas Medical Center, 1.3 km from Twilight Epiphany Skyspace
9.4 out of 10, Exceptional, (1,007 reviews)
"Great stay!"
United States
Luke
The price is CA $216
CA $281 total
includes taxes & fees
Nov 22 - Nov 23
InterContinental Houston by IHG
A hotel room with a desk, two beds, a sofa, and a large mirror.

3. Residence Inn By Marriott Houston Medical Center Reliant Park

Residence Inn By Marriott Houston Medical Center Reliant Park
3.0 star property
Texas Medical Center, 2.8 km from Twilight Epiphany Skyspace
9.4 out of 10, Exceptional, (604 reviews)
"Nice place to stay close to everything"
Canada
Najwinder
The price is CA $229
CA $267 total
includes taxes & fees
Nov 27 - Nov 28
Residence Inn By Marriott Houston Medical Center Reliant Park
A rooftop pool area with lounge chairs and a view of a tall building at night.

4. The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center, 1.2 km from Twilight Epiphany Skyspace
9.2 out of 10, Wonderful, (1,282 reviews)
"Good hotel. Clean and nice staff."
United States
Ariane
The price is CA $169
CA $210 total
includes taxes & fees
Nov 22 - Nov 23
The Westin Houston Medical Center/Museum District
A spacious hotel lobby with high ceilings, large windows, a long bar area, and a seating area with a sofa and chairs.

5. Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center
3.0 star property
Texas Medical Center, 2.6 km from Twilight Epiphany Skyspace
9.2 out of 10, Wonderful, (2,737 reviews)
"Great place to stay"
United States
Joel
The price is CA $177
CA $208 total
includes taxes & fees
Nov 21 - Nov 22
Hyatt Place Houston Medical Center
An outdoor patio area with round wooden tables and wicker chairs, featuring a lantern and modern lighting fixtures.

6. Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX
3.0 star property
Texas Medical Center, 2.7 km from Twilight Epiphany Skyspace
9.2 out of 10, Wonderful, (1,009 reviews)
"Will stay again , highly recommend!"
United States
Shatara
The price is CA $150
CA $176 total
includes taxes & fees
Nov 21 - Nov 22
Hilton Garden Inn Houston Medical Center, TX
A spacious hotel lobby with high ceilings, large windows, a long bar area, and a seating area with a sofa and chairs.

7. Hyatt House Houston Medical Center

Hyatt House Houston Medical Center
3.0 star property
Texas Medical Center, 2.6 km from Twilight Epiphany Skyspace
9.2 out of 10, Wonderful, (1,291 reviews)
"Clean rooms, helpful staff, and great breakfast."
United States
Nikki
The price is CA $177
CA $208 total
includes taxes & fees
Dec 6 - Dec 7
Hyatt House Houston Medical Center
A spacious living area with a dining table, chairs, and a chandelier.

8. Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
1.8 km from Twilight Epiphany Skyspace
9.2 out of 10, Wonderful, (1,013 reviews)
"Courteous staff, conveniently located. Very good amenities."
United States
David
The price is CA $274
CA $387 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Zaza Houston Museum District
An outdoor patio area with round wooden tables and wicker chairs, featuring a lantern and modern lighting fixtures.

9. Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX
3.0 star property
Texas Medical Center, 2.7 km from Twilight Epiphany Skyspace
9.2 out of 10, Wonderful, (763 reviews)
"This room was spacious and had more amenities than a normal in a double queen room. We enjoyed our stay and will come here again!"
United States
Colleen
The price is CA $180
CA $210 total
includes taxes & fees
Nov 22 - Nov 23
Home2 Suites by Hilton Houston Medical Center, TX
A high-rise hotel with a rooftop pool, multiple floors, and a cityscape view.

10. Sentral Forme Houston

Sentral Forme Houston
4.5 star property
2.4 km from Twilight Epiphany Skyspace
9.2 out of 10, Wonderful, (102 reviews)
"Enjoyable stay with all the comforts of home."
United States
ebony noelle
The price is CA $268
CA $355 total
includes taxes & fees
Dec 13 - Dec 14
Sentral Forme Houston
A hotel lobby with a grand chandelier, a reception desk, and a carpet with the hotel's name.

11. Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center, 2.3 km from Twilight Epiphany Skyspace
9.0 out of 10, Wonderful, (3,827 reviews)
"Great hotel definitely would stay again."
United States
Michael
The price is CA $208
CA $244 total
includes taxes & fees
Nov 22 - Nov 23
Blossom Hotel Houston, Curio Collection by Hilton
A modern restaurant with a bar area, featuring a patterned floor, multiple dining tables, and contemporary lighting fixtures.

12. Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
Texas Medical Center, 1.2 km from Twilight Epiphany Skyspace
9.0 out of 10, Wonderful, (1,000 reviews)
"Location was best"
United States
Nafisa
The price is CA $216
CA $298 total
includes taxes & fees
Nov 22 - Nov 23
Houston Marriott Medical Center/Museum District
A bar area with a long counter, bar stools, a refrigerated display case with beverages, and a menu board above the counter.

13. Courtyard By Marriott Houston Medical Center Reliant Park

Courtyard By Marriott Houston Medical Center Reliant Park
3.0 star property
2.5 km from Twilight Epiphany Skyspace
8.8 out of 10, Excellent, (1,002 reviews)
"The hotel was conveniently located for walking to Rice University and the room was clean and comfortable."
United States
Reagan
The price is CA $140
CA $165 total
includes taxes & fees
Nov 15 - Nov 16
Courtyard By Marriott Houston Medical Center Reliant Park
A modern kitchen with a central island, stainless steel bar stools, a black refrigerator, and white cabinetry.

14. Modern B & B

Modern B & B
3.5 star property
Montrose, 2 km from Twilight Epiphany Skyspace
9.0 out of 10, Wonderful, (254 reviews)
"Neighborhood was nice"
United States
LISA
The price is CA $112
CA $131 total
includes taxes & fees
Nov 13 - Nov 14
Modern B & B
A modern kitchen with a bar area, wooden stools, and a seating area with chairs.

15. SpringHill Suites Houston Medical Center/NRG Park

SpringHill Suites Houston Medical Center/NRG Park
3.0 star property
Astrodome, 2.9 km from Twilight Epiphany Skyspace
8.8 out of 10, Excellent, (1,001 reviews)
"The room was clean, the hotel was within walking distance to Reliant Stadium, and the breakfast was fantastic! Very happy with our stay."
United States
Jennifer
The price is CA $161
CA $188 total
includes taxes & fees
Dec 8 - Dec 9
SpringHill Suites Houston Medical Center/NRG Park
A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

16. Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center, 1.1 km from Twilight Epiphany Skyspace
8.6 out of 10, Excellent, (2,252 reviews)
"Very nice, would stay again!"
United States
Amanda
The price is CA $140
CA $165 total
includes taxes & fees
Nov 29 - Nov 30
Hilton Houston Plaza/Medical Center
A modern living room with a staircase, a sofa set, a glass coffee table, and a flat-screen TV.

17. DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza
4.0 star property
Greenway Plaza-Upper Kirby, 2.7 km from Twilight Epiphany Skyspace
8.4 out of 10, Very good, (1,978 reviews)
"Was clean and staff was very friendly"
United States
Scott
The price is CA $119
CA $140 total
includes taxes & fees
Nov 22 - Nov 23
DoubleTree by Hilton Hotel Houston - Greenway Plaza
A spacious dining area with multiple tables and chairs, large windows, and hanging pendant lights.

18. DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
Texas Medical Center, 1.3 km from Twilight Epiphany Skyspace
8.4 out of 10, Very good, (722 reviews)
"Nice and convenient to the medical center"
United States
CHRISTY
The price is CA $160
CA $187 total
includes taxes & fees
Nov 23 - Nov 24
DoubleTree by Hilton Houston Medical Center Hotel & Suites
A reception desk with a wooden panel, two computer monitors, and a large illuminated 'H' sign.

19. Holiday Inn Houston Reliant Park Area

Holiday Inn Houston Reliant Park Area
3.0 star property
Astrodome, 3.2 km from Twilight Epiphany Skyspace
8.4 out of 10, Very good, (1,000 reviews)
"Loved and enjoyed the stay"
United States
Maria
The price is CA $146
CA $171 total
includes taxes & fees
Dec 13 - Dec 14
Holiday Inn Houston Reliant Park Area
A modern dining area with a long table and chairs, a chandelier, and a television on the wall.

20. Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park
2.5 star property
Texas Medical Center, 2.6 km from Twilight Epiphany Skyspace
8.4 out of 10, Very good, (1,013 reviews)
"Everyone was kind and helpful! Check in was easy and staff was accommodating when we need to stay an extra night for medical reasons. Hotel is super convenient to out medical appointments."
United States
Ana
The price is CA $156
CA $183 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn & Suites Houston Medical Center NRG Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels near Twilight Epiphany Skyspace

A modern building with multiple floors, large windows, and outdoor seating area with chairs and tables.

Hotel Saint Augustine

3.5 star property
Montrose, 2.1 km from Twilight Epiphany Skyspace
View
A modern hotel building with a prominent entrance, large windows, and a visible name sign.

InterContinental Houston by IHG

4.0 star property
Texas Medical Center, 1.3 km from Twilight Epiphany Skyspace
View
A hotel room with a desk, two beds, a sofa, and a large mirror.

Residence Inn By Marriott Houston Medical Center Reliant Park

3.0 star property
Texas Medical Center, 2.8 km from Twilight Epiphany Skyspace
View
A rooftop pool area with lounge chairs and a view of a tall building at night.

The Westin Houston Medical Center/Museum District

4.0 star property
Texas Medical Center, 1.2 km from Twilight Epiphany Skyspace
View
A spacious hotel lobby with high ceilings, large windows, a long bar area, and a seating area with a sofa and chairs.

Hyatt Place Houston Medical Center

3.0 star property
Texas Medical Center, 2.6 km from Twilight Epiphany Skyspace
View
9.6
Exceptional
190 reviews
9.4
Exceptional
1,007 reviews
9.4
Exceptional
604 reviews
9.2
Wonderful
1,282 reviews
9.2
Wonderful
2,737 reviews
The price is CA $419
CA $494 total
includes taxes & fees
Nov 29 - Nov 30
The price is CA $216
CA $281 total
includes taxes & fees
Nov 22 - Nov 23
The price is CA $229
CA $267 total
includes taxes & fees
Nov 27 - Nov 28
The price is CA $169
CA $210 total
includes taxes & fees
Nov 22 - Nov 23
The price is CA $177
CA $208 total
includes taxes & fees
Nov 21 - Nov 22
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • No WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Hotels recommended for families near Twilight Epiphany Skyspace

A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center
8.6 out of 10, Excellent, (2,252)
The price is CA $140
CA $165 total
includes taxes & fees
Nov 29 - Nov 30
Hilton Houston Plaza/Medical Center

Other attractions near Twilight Epiphany Skyspace

A city skyline with tall buildings and a highway with light trails.

Main Street Theater - Rice Village

You can enjoy a show at Main Street Theater - Rice Village during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
See properties

Top Twilight Epiphany Skyspace Hotel Reviews

A modern hotel building with a prominent entrance, large windows, and a visible name sign.
InterContinental Houston by IHG

InterContinental Houston by IHG

InterContinental Houston by IHG
Texas Medical Center

10/10 Excellent

Clean room and professional staff
Canada
Michel
Reviewed September 8, 2026
InterContinental Houston by IHG

Frequently Asked Questions

What's the area like around Twilight Epiphany Skyspace?

Twilight Epiphany Skyspace is located in an area of Houston known for its popular theater scene and top museums. If you're looking for a convenient place to stay, check out the 67 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Twilight Epiphany Skyspace?

Hilton Houston Plaza/Medical Center is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and 2 bars. It's located just a short 0.7 mi (1.1 km) from Twilight Epiphany Skyspace. Other good options close by include The Westin Houston Medical Center/Museum District and InterContinental Houston by IHG.

How many hotels will I find close to Twilight Epiphany Skyspace?

Expedia has 67 hotels and other accommodations within a mile from Twilight Epiphany Skyspace.

If I need to cancel the hotel reservation for my stay near Twilight Epiphany Skyspace, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable as long as you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the best options available near Twilight Epiphany Skyspace.

Where can I learn more about changing or cancelling my trip in the area near Twilight Epiphany Skyspace?

To find more details about changing or cancelling your stay near Twilight Epiphany Skyspace, go to https://www.expedia.com/service/.

What can I see and do near Twilight Epiphany Skyspace?

Houston Natural Science Museum, Houston Museum of Fine Arts, and Menil Collection feature a variety of fascinating exhibits to see while you're in town. While you're exploring, swing by Reliant Park, Eldorado Ballroom, and Freedmenstown to learn a bit about the area. You can catch a show at Main Street Theater - Rice Village, House of Blues Houston, and Bayou Music Center.

How can I get to Twilight Epiphany Skyspace?

With so many transportation options, seeing the area around Twilight Epiphany Skyspace is a breeze. Walk to nearby metro stations like Elgin/Third Ward Station, TSU/UH Athletics District Station, and Ensemble/HCC Station. To explore the surrounding area, hop aboard a train at M. D. Anderson Station or Kinder Station.

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