Title: The 10 Best Hotels Near The Children’s Museum of the Upstate, Greenville from CA $96 | Expedia.ca [Greenville Downtown Travel Guide](https://expedia.ca/Greenville-Greenville-Downtown.dx6348006)[The Children’s Museum of the Upstate Car Rentals](https://expedia.ca/Car-Rentals-In-The-Childrens-Museum-Of-The-Upstate.d553248621532656777.Car-Rental-Guide)[The Children’s Museum of the Upstate Vacations](https://expedia.ca/The-Childrens-Museum-Of-The-Upstate-Greenville-Downtown.d553248621532656777.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near The Children’s Museum of the Upstate, Greenville from CA $96 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248621532656777&startDate=2025-10-25&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 26 - Oct 27](https://www.expedia.ca/Hotel-Search?regionId=553248621532656777&startDate=2025-10-26&endDate=2025-10-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248621532656777&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248621532656777&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Top Hotels Close to The Children’s Museum of the Upstate ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/663800/663745/5698a443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/670000/663800/663745/f9b74c9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/670000/663800/663745/b23cade1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/1000000/670000/663800/663745/3e9b9973.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pettigru Place Bed & Breakfast Pettigru Street Historic District, 1.2 km from The Children’s Museum of the Upstate 10/10 Exceptional (123) "One of my favorite places to stay in Greenville. It is such a quaint bed and breakfast despite how close it is to downtown. Excellent service and amazing accommodations. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lendell CA $325 CA $357 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Greenville-Hotels-Pettigru-Place-Bed-Breakfast.h663745.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/b9f7d424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/c23921a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/0c07d0d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/c1f887b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Greenville Downtown Greenville Downtown, 0.7 km from The Children’s Museum of the Upstate 9.6/10 Exceptional (1002) "Great location, restaurants and shopping nearby. Hotel itself was also excellent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard CA $194 CA $213 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/88b33cc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking | Private kitchen](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/b8a8a3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/8e2d308e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/a74bbe34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Greenville Downtown West End, 1.6 km from The Children’s Museum of the Upstate 9.6/10 Exceptional (1000) "Great location, beautiful views (from our room). " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeff A. CA $189 CA $214 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville-Downtown.h29050020.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/dd539dcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-c3100c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/924dd6ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection Greenville Downtown, 1.2 km from The Children’s Museum of the Upstate 9.6/10 Exceptional (394) "Very expensive but great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Ellen CA $391 CA $442 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/4000000/3380000/3374200/3374120/d892ebd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3380000/3374200/3374120/38dda9df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/4000000/3380000/3374200/3374120/8634128c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3380000/3374200/3374120/537f83e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Greenville Downtown Greenville Downtown, 0.8 km from The Children’s Museum of the Upstate 9.4/10 Exceptional (1000) "It was very clean and comfortable and we enjoyed this stay very much" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin CA $213 CA $234 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Greenville-Hotels-Courtyard-By-Marriott-Greenville-Downtown.h3374120.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/32000000/31720000/31718800/31718786/865e596e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/32000000/31720000/31718800/31718786/b5f52cde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/32000000/31720000/31718800/31718786/f9a331a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/32000000/31720000/31718800/31718786/9e121233.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Greenville Downtown Greenville Downtown, 0.7 km from The Children’s Museum of the Upstate 9.4/10 Exceptional (331) "I have stayed at this hotel many times and have never been disappointed. The rooms are very nice and it is very convenient to downtown shopping and restaurants. The restaurant and breakfast are very good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane CA $225 CA $248 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Greenville-Hotels-Residence-Inn-By-Marriott-Greenville-Downtown.h31718786.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/d9184989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking, River View](https://images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/05a2709e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/1546f0c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/ef19c1cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Greenville-Downtown-RiverPlace Greenville Downtown, 1 km from The Children’s Museum of the Upstate 9.4/10 Exceptional (1002) "Clean and nice place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karina CA $200 CA $226 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Downtown-RiverPlace.h1460359.Hotel-Information) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/dac522c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/486bef86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/0a338dee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/b5b2534d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Greenville Downtown Greenville Downtown, 1 km from The Children’s Museum of the Upstate 9.2/10 Wonderful (1001) "Excellent location close to everything we wanted to see and we really enjoyed the hot breakfast during our stay too! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cathy CA $165 CA $182 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/16000000/15220000/15217400/15217348/75fc615c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/16000000/15220000/15217400/15217348/6ae45980.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, dishwasher, cookware/dishes/utensils](https://images.trvl-media.com/lodging/16000000/15220000/15217400/15217348/43d7334f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15220000/15217400/15217348/cee4afe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Greenville Downtown Greenville Downtown, 0.4 km from The Children’s Museum of the Upstate 9.2/10 Wonderful (985) "Great room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $159 CA $175 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Greenville-Hotels-Home2-Suites-By-Hilton-Greenville-Downtown.h15217348.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/3e47bf88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/93cc35df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/02c3589b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/e5bdee00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Poinsett Greenville Greenville Downtown, 0.7 km from The Children’s Museum of the Upstate 9.2/10 Wonderful (1005) "Very courteous and helpful staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ANDREW CA $265 CA $291 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/575c54cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/2fc877f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar, tapas bar](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/5385e1d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/w4000h2665x0y2-7a2b5501.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel By Marriott Greenville Greenville Downtown, 1 km from The Children’s Museum of the Upstate 9.2/10 Wonderful (681) "Perfectly located hotel right on Main St with plenty of walkable dinner options and a great rooftop bar." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Patrick CA $232 CA $256 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-AC-Hotel-By-Marriott-Greenville.h58282504.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b3d797da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/62c16e21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/9895027f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton Greenville Downtown Riverplace Greenville Downtown, 1 km from The Children’s Museum of the Upstate 9.2/10 Wonderful (1002) "Very enjoyable location and hospitality. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mitchell CA $212 CA $233 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/a1d7ed0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/7c5ccfc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/5e9a8e7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Greenville Downtown Greenville Downtown, 0.4 km from The Children’s Museum of the Upstate 9.0/10 Wonderful (1001) "Perfect place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie CA $175 CA $193 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/11000000/10250000/10240700/10240653/cba17315.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/11000000/10250000/10240700/10240653/546c8477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/11000000/10250000/10240700/10240653/eb4c59a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/11000000/10250000/10240700/10240653/48d7212d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swamp Rabbit Inn West End, 1.2 km from The Children’s Museum of the Upstate 9.0/10 Wonderful (351) "Rooms were very clean and had everything I needed. Keypad access was cool and came in handy! Only stayed overnight but would definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sophie CA $162 CA $193 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Greenville-Hotels-Swamp-Rabbit-Inn.h10240653.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/809400/809310/22530ef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/810000/809400/809310/9540d7bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/810000/809400/809310/8b983056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/810000/809400/809310/3c3585c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Greenville - Downtown by IHG Greenville Downtown, 0.3 km from The Children’s Museum of the Upstate 8.8/10 Excellent (1010) "Great price for the location and amenities plus decent breakfast options." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $162 CA $179 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Greenville-Hotels-Holiday-Inn-Express-Hotel-Suites-Greenville-Downtown.h809310.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/e6cea43c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/e6ee6bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/1fe5c84c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Greenville Greenville Downtown, 0.4 km from The Children’s Museum of the Upstate 8.6/10 Excellent (1004) "Great location, friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Layne CA $189 CA $214 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/f974826b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/0aaf2649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/e6475e9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/d16127a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Boutique Hotel, BW Signature Collection 2.3 km from The Children’s Museum of the Upstate 8.0/10 Very good (897) "We enjoyed our stay. The hotel staff in all areas were great. Loved the sitting area outside our room on the 2nd floor." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Claire CA $87 CA $96 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/41300/41221/f017a576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41300/41221/fbbbf12f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/41300/41221/a5be5aef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/41300/41221/dc5706bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Greenville near downtown 2.6 km from The Children’s Museum of the Upstate 7.0/10 Good (693) "Clean room, good location and friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Glennys CA $102 CA $112 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Greenville-Hotels-Quality-Inn-Suites.h41221.Hotel-Information) ![Deluxe Studio, 2 Double Beds](https://images.trvl-media.com/lodging/108000000/107970000/107962200/107962175/6c37dc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107970000/107962200/107962175/428a3294.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio, 2 Double Beds](https://images.trvl-media.com/lodging/108000000/107970000/107962200/107962175/cad1b591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room, 2 Double Beds](https://images.trvl-media.com/lodging/108000000/107970000/107962200/107962175/0c4c1315.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tanglewood Inn 6.4 km from The Children’s Museum of the Upstate 10/10 Exceptional (6) "We loved our stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cassidy CA $211 CA $233 total includes taxes & fees Nov 25 - Nov 26 [](https://www.expedia.ca/Greenville-Hotels-Tanglewood-Inn.h107962175.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/43000000/42640000/42633300/42633276/e0ede3d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/43000000/42640000/42633300/42633276/c2b1f476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/43000000/42640000/42633300/42633276/b257df86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/43000000/42640000/42633300/42633276/7f93b55c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Greenville - Taylors by IHG 5.1 km from The Children’s Museum of the Upstate 9.0/10 Wonderful (648) "Clean, comfortable beds, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nathonia CA $158 CA $174 total includes taxes & fees Nov 14 - Nov 15 [](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Holiday-Inn-Express-And-Suites-Greenville-Taylors.h42633276.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-09&endDate=2025-11-10®ionId=553248621532656777&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top The Children’s Museum of the Upstate Hotel Reviews ![Hyatt Place Greenville Downtown](//images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/dac522c0_y.jpg) ### Hyatt Place Greenville Downtown 10/10 Excellent "Impressed with the variety of options and taste of food at breakfast. Hotel was affordable in relation to downtown. Beds we’re comfortable. " [](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information) ![Mint House Greenville - Downtown](//images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/a4b477d7_y.jpg) ### Mint House Greenville - Downtown 10/10 Excellent "The property is well located and the building is secure, safe, clean and comfortable. " [](https://expedia.ca/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) ![SpringHill Suites by Marriott Greenville Downtown](//images.trvl-media.com/lodging/32000000/31720000/31719000/31718906/b9f7d424_y.jpg) ### SpringHill Suites by Marriott Greenville Downtown 10/10 Excellent "Loved this hotel! Staff was amazing. The hotel was very clean and updated. Outdoor pool, bikes, restaurant onsite. Two blocks off Main Street. " [](https://expedia.ca/Greenville-Hotels-SpringHill-Suites-By-Marriott-Greenville-Downtown.h31718906.Hotel-Information) ![Holiday Inn Express & Suites Greenville - Downtown by IHG](//images.trvl-media.com/lodging/1000000/810000/809400/809310/22530ef8_y.jpg) ### Holiday Inn Express & Suites Greenville - Downtown by IHG 10/10 Excellent "It’s pet friendly so if u don’t have pets ask to stay in a room that is not pet friendly . Some pets leave smells but the staff will switch ur room . " [](https://expedia.ca/Greenville-Hotels-Holiday-Inn-Express-Hotel-Suites-Greenville-Downtown.h809310.Hotel-Information) ![Downtown Condo Steps to Main Street](//images.trvl-media.com/lodging/111000000/110030000/110022500/110022456/0fae982f_y.jpg) ### Downtown Condo Steps to Main Street 10/10 Excellent "Can’t beat the location and property! Walking distance to all the shops, restaurants, etc. Hunter was a great host! Would definitely stay again! " [](https://expedia.ca/Greenville-Hotels-Downtown-Condo-Steps-To-Main-Street.h110022456.Hotel-Information) ![Hyatt Regency Greenville](//images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Extremely convenient for walking to restaurants and stores!" [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Hampton Inn & Suites Greenville-Downtown-RiverPlace](//images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/d9184989_y.jpg) ### Hampton Inn & Suites Greenville-Downtown-RiverPlace 10/10 Excellent "This was an ideal location. Close enough to Main Street without being right in the heart of it. The river and riverwalk right outside the door, with the Falls Park right around the corner....and superior food options, all within walking distance of 10 minutes or less. Can't wait to go back, wonderful weekend getaway destination!" [](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Downtown-RiverPlace.h1460359.Hotel-Information) ![Aloft Greenville Downtown](//images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51_y.jpg) ### Aloft Greenville Downtown 10/10 Excellent "Loved our stay! Hotel had super easy check in, friendly staff, hip feeling and awesome location! Nice lobby/bar area to hang out with friends and have super yummy cocktails as well! Highly recommend! " [](https://expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Home2 Suites by Hilton Greenville Downtown](//images.trvl-media.com/lodging/16000000/15220000/15217400/15217348/75fc615c_y.jpg) ### Home2 Suites by Hilton Greenville Downtown 10/10 Excellent "Thank you to the Manager Hayleigh was very helpful in accommodating our early check in, all staff was friendly, greeting. Room was so clean and spotless. Valet guys were great too. Very nice stay. TY" [](https://expedia.ca/Greenville-Hotels-Home2-Suites-By-Hilton-Greenville-Downtown.h15217348.Hotel-Information) ## Hotels near other The Children’s Museum of the Upstate attractions [](https://www.expedia.ca/Greenville-County-Museum-Of-Art-Hotels.0-l6082717-0.Travel-Guide-Filter-Hotels) ### Greenville County Museum of Art You can spend an afternoon studying the exhibits at Greenville County Museum of Art during your travels in Greenville. Stroll along the riverfront or experience the acclaimed theater scene in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082717) [](https://www.expedia.ca/Greenville-Little-Theater-Hotels.0-l553248621558035372-0.Travel-Guide-Filter-Hotels) ### Greenville Little Theater You can make plans for a show at Greenville Little Theater during your stay in Greenville. Stroll along the riverfront or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558035372) [](https://www.expedia.ca/Heritage-Green-Hotels.0-l553248621558035373-0.Travel-Guide-Filter-Hotels) ### Heritage Green Explore the great outdoors at Heritage Green, a lovely green space in Greenville. Experience the acclaimed theater scene and great live music in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558035373) [](https://www.expedia.ca/Upcountry-History-Museum-Hotels.0-l553248621532656775-0.Travel-Guide-Filter-Hotels) ### Upcountry History Museum You can spend time browsing the exhibits at Upcountry History Museum in Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532656775) [](https://www.expedia.ca/Piazza-Bergamo-Hotels.0-l553248621558035371-0.Travel-Guide-Filter-Hotels) ### Piazza Bergamo Explore the great outdoors at Piazza Bergamo, a lovely green space in Greenville. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621558035371) [](https://www.expedia.ca/Alchemy-Comedy-Theater-Hotels.0-l553248621532656773-0.Travel-Guide-Filter-Hotels) ### Alchemy Comedy Theater You can enjoy a show at Alchemy Comedy Theater during your stay in Greenville. Experience the great live music and acclaimed theater scene in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532656773) [](https://www.expedia.ca/Centre-Stage-Hotels.0-l553248621532656774-0.Travel-Guide-Filter-Hotels) ### Centre Stage You can get tickets for a performance at Centre Stage during your stay in Greenville. Stroll along the riverfront or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532656774) [](https://www.expedia.ca/Kilgore-Lewis-House-Hotels.0-l6082719-0.Travel-Guide-Filter-Hotels) ### Kilgore Lewis House Find out about the history of Greenville when you take a trip to Kilgore Lewis House. Stroll along the riverfront or experience the acclaimed theater scene in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082719) ## Frequently asked questions ### What's the area like around The Children's Museum of the Upstate? > The Children's Museum of the Upstate is located in a family-friendly area of Greenville known for its beautiful river views and great live music scene. If you're looking for a convenient place to stay, check out the 128 hotels and other accommodations you'll find within a mile. ### What's the best hotel to stay near The Children's Museum of the Upstate? > Adjacent to The Children's Museum of the Upstate, [Hyatt Regency Greenville](https://www.expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a 24-hour fitness center. Other good choices within a short distance include [Hyatt Place Greenville Downtown](https://www.expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information) and [Aloft Greenville Downtown](https://www.expedia.ca/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information). ### How many hotels will I find close to The Children's Museum of the Upstate? > Expedia has 128 hotels and other accommodations within a mile from The Children's Museum of the Upstate. ### If I need to cancel the hotel reservation for my stay near The Children's Museum of the Upstate, will I receive a refund? > Yes! You'll find that most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer near The Children's Museum of the Upstate. ### What can I see and do near The Children's Museum of the Upstate? > You'll want to browse the collections at Greenville County Museum of Art, Museum and Library of Confederate History, and Shoeless Joe Jackson Museum. Beattie House, Greenville Little Theater, and Kilgore Lewis House are some of the notable landmarks to see in the area. You can watch performances at The Peace Center, Alchemy Comedy Theater, and Centre Stage if you're interested in local theater. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [3 Star Hotels in Greenville](https://www.expedia.ca/3Star-Greenville-Hotels.s30-0-d1388.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Greenville](https://www.expedia.ca/5Star-Greenville-Hotels.s50-0-d1388.Travel-Guide-Filter-Hotels) - [Berea Hotels](https://www.expedia.ca/Berea-Hotels.d553248634999109152.Travel-Guide-Hotels) - [Hotels near Bob Jones University](https://www.expedia.ca/Bob-Jones-University-Hotels.0-l6169875-0.Travel-Guide-Filter-Hotels) - [Hotels near Bon Secours Wellness Arena](https://www.expedia.ca/Bon-Secours-Wellness-Arena-Hotels.0-l6082715-0.Travel-Guide-Filter-Hotels) - [Hotels near Centre Stage](https://www.expedia.ca/Centre-Stage-Hotels.0-l553248621532656774-0.Travel-Guide-Filter-Hotels) - [Colonel Elias Earle Historic District Hotels](https://www.expedia.ca/Colonel-Elias-Earle-Historic-District-Greenville-Hotels.0-n6348165-0.Travel-Guide-Filter-Hotels) - 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[Flights from Seattle to Greenville](https://www.expedia.ca/lp/flights/178307/1388/seattle-to-greenville) - [Flights from Sydney to Greenville](https://www.expedia.ca/lp/flights/178312/1388/sydney-to-greenville) - [Flights from Victoria to Greenville](https://www.expedia.ca/lp/flights/4138/1388/victoria-to-greenville) - [Flights from Tulsa to Greenville](https://www.expedia.ca/lp/flights/602327/1388/tulsa-to-greenville) - [Flights from Madison to Greenville](https://www.expedia.ca/lp/flights/602704/1388/madison-to-greenville) - [Flights from Louisville to Greenville](https://www.expedia.ca/lp/flights/603002/1388/louisville-to-greenville) - [Flights from Stuttgart to Greenville](https://www.expedia.ca/lp/flights/6047258/1388/stuttgart-to-greenville) - [Flights from Belo Horizonte to Greenville](https://www.expedia.ca/lp/flights/6053272/1388/belo-horizonte-to-greenville) - [Flights from Edgewater to Greenville](https://www.expedia.ca/lp/flights/6348965/1388/edgewater-to-greenville) - [Flights from Groton to Greenville](https://www.expedia.ca/lp/flights/6398/1388/groton-to-greenville) - [Flights from Greer to Greenville](https://www.expedia.ca/lp/flights/7381/1388/greer-to-greenville) - [Flights from Greenwood to Greenville](https://www.expedia.ca/lp/flights/7509/1388/greenwood-to-greenville) - [Flights from Fletcher to Greenville](https://www.expedia.ca/lp/flights/8207/1388/fletcher-to-greenville) - [Flights from Middletown to Greenville](https://www.expedia.ca/lp/flights/8865/1388/middletown-to-greenville) - [Central Vacations](https://www.expedia.ca/Central.d10503.Destination-Travel-Guides) - [Greenville Vacations](https://www.expedia.ca/Greenville.d1388.Destination-Travel-Guides) - [Visit Greenville](https://www.expedia.ca/Greenville.dx1388) - [Avis Rental Cars in Greenville](https://www.expedia.ca/Avis-Car-Rentals-In-Greenville.d1388-c41.Car-Rental-Guide-Suppliers) - [Budget Rental Cars in Greenville](https://www.expedia.ca/Budget-Car-Rentals-In-Greenville.d1388-c39.Car-Rental-Guide-Suppliers) - [Car rental Greenville](https://www.expedia.ca/Car-Rentals-In-Greenville.d1388.Car-Rental-Guide) - [Dollar Rent A Car Rental Cars in Greenville](https://www.expedia.ca/Dollar-Rent-A-Car-Car-Rentals-In-Greenville.d1388-c43.Car-Rental-Guide-Suppliers) - [Easirent.com Rental Cars in Greenville](https://www.expedia.ca/Easirentcom-Car-Rentals-In-Greenville.d1388-c1017.Car-Rental-Guide-Suppliers) - [Enterprise Rental Cars in Greenville](https://www.expedia.ca/Enterprise-Car-Rentals-In-Greenville.d1388-c15.Car-Rental-Guide-Suppliers) - [Europcar Rental Cars in Greenville](https://www.expedia.ca/Europcar-Car-Rentals-In-Greenville.d1388-c14.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Greenville](https://www.expedia.ca/Hertz-Car-Rentals-In-Greenville.d1388-c40.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in Greenville](https://www.expedia.ca/Thrifty-Car-Rental-Car-Rentals-In-Greenville.d1388-c45.Car-Rental-Guide-Suppliers) - [Wiber Rental Cars in Greenville](https://www.expedia.ca/WIber-Car-Rentals-In-Greenville.d1388-c1127.Car-Rental-Guide-Suppliers) - [Greenville Vacation Rentals](https://www.expedia.ca/Greenville-Vacation-Rentals.d1388.Travel-Guide-VacationRentals) - [Things to do in Greenville](https://www.expedia.ca/Things-To-Do-In-Greenville.d1388.Travel-Guide-Activities)