Title: 10 Best Greenville County Luxury Resorts & Hotels for 2025 | Expedia.ca [Greenville County Hotels](https://expedia.ca/Destinations-In-Greenville-County.d553248635976432805.Hotel-Destinations)[Vacation Rentals in Greenville County](https://expedia.ca/Destinations-In-Greenville-County.d553248635976432805.Vacation-Rental-Destinations)[Greenville County Flights](https://expedia.ca/Destinations-In-Greenville-County.d553248635976432805.Flight-Destinations)[Greenville County Car Rentals](https://expedia.ca/Destinations-In-Greenville-County.d553248635976432805.Car-Rental-Destinations)[Greenville County Vacations](https://expedia.ca/Greenville-County.d553248635976432805.Destination-Travel-Guides) ![Greenville - Spartanburg](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Visit Greenville, South Carolina # Luxury Hotels & Resorts in Greenville County - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Greenville County ![](https://mediaim.expedia.com/destination/1/92cc7a0efb86c396d8be1a2fca0ded04.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Travelers Rest [](https://expedia.ca/Travelers-Rest-Hotels-Luxury-Hotel.0-0-d180879-tLuxuryHotel.Travel-Guide-Filter-Hotels) ![Greenville featuring a city, a bridge and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63754-Greenville-Spartanburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Greenville [](https://expedia.ca/Greenville-Hotels-Luxury-Hotel.0-0-d1388-tLuxuryHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/2/6a8023c8efd6069e3b87e444c8929ba4.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Greer [](https://expedia.ca/Greer-Hotels-Luxury-Hotel.0-0-d7381-tLuxuryHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/2/8b459811334da6c7bb81cab571c8f05f.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Cleveland [](https://expedia.ca/Cleveland-Hotels-Luxury-Hotel.0-0-d6348031-tLuxuryHotel.Travel-Guide-Filter-Hotels) ## Check availability on Greenville County Luxury Hotels Tonight [Nov 14 - Nov 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976432805&startDate=2025-11-14&endDate=2025-11-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Nov 15 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976432805&startDate=2025-11-15&endDate=2025-11-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248635976432805&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248635976432805&startDate=2025-11-21&endDate=2025-11-23&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Greenville County Luxury Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Greenville-County-Luxury-Hotel.0-0-d553248635976432805-tLuxuryHotel.Hotel-Filter-Destinations)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Greenville-County-Luxury-Hotel.0-0-d553248635976432805-tLuxuryHotel.Hotel-Filter-Destinations) ## Top Greenville County Hotel Reviews ![La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.](//images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/1fc30205_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd. 10/10 Excellent "The hotel was extremely clean and the stsff was kind and accommodating. " [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) ![Urban Boutique Hotel, BW Signature Collection](//images.trvl-media.com/lodging/1000000/30000/24400/24334/f974826b_y.jpg) ### Urban Boutique Hotel, BW Signature Collection 10/10 Excellent "For the price the property was very nice and clean. " [](https://expedia.ca/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](//images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "." [](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Hyatt Place Greenville/Haywood](//images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "Staff was Great! " [](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![Grand Bohemian Lodge Greenville, Autograph Collection](//images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3_y.jpg) ### Grand Bohemian Lodge Greenville, Autograph Collection 10/10 Excellent "The staff were really sweet and responsive. The views from the rooms are breathtaking! " [](https://expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Drury Inn & Suites Greenville](//images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Nice perks for staying over the weekend " [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Hyatt Regency Greenville](//images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "Convenient to Main Street area. " [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Motel 6 Greenville, SC](//images.trvl-media.com/lodging/2000000/1110000/1107500/1107497/af5363f6_y.jpg) ### Motel 6 Greenville, SC 10/10 Excellent "I had never stayed here before but the rates were much better than all the others so I was kind of skeptical at first. But upon arriving and checking the room out, I was pleasantly pleased. It comes with a small kitchen area which most do not, especially for the price. I would definitely stay here again and would recommend it to others. The staff are very nice and helpful and that’s a rarity as well. My wife keeps a log on the good, bad and ugly of the rooms we stay in for a future reference and this will most assuredly go into the good list. " [](https://expedia.ca/Greenville-Hotels-Motel-6-Greenville.h1107497.Hotel-Information) ![Hilton Greenville](//images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Clean and safe" [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [3 Star Hotels in Greenville](https://www.expedia.ca/3Star-Greenville-Hotels.s30-0-d1388.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Greenville](https://www.expedia.ca/5Star-Greenville-Hotels.s50-0-d1388.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotel-With-Pool.0-0-d242-tHotelwithPool.Hotel-Filter-Destinations) - [Hotels with Balconies in South Carolina](https://www.expedia.ca/Destinations-In-South-Carolina-Hotels-With-Balconies.0-0-d242-tHotelswithBalconies.Hotel-Filter-Destinations) - 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