Texas Medical Center Vacation Packages

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    Save up to CA $1,096 when you book a flight and hotel together*

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Top Holiday Package Deals in Texas Medical Center

Price found within the past 48 hours. Click for updated prices.
La Colombe d'Or Hotel

La Colombe d'Or Hotel

5 out of 5
Montrose
Price was CA $1,266, price is now CA $1,043 per person
CA $1,043
per person
Apr 30 - May 2
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to Houston (IAH)
9.4/10 Exceptional! (168 reviews)
Absolutely lovely place, and I'd highly recommend it!

Reviewed on Mar 10, 2026

Landing Apartments - Grand Harbor

Landing Apartments - Grand Harbor

4 out of 5
Price was CA $1,888, price is now CA $1,494 per person
CA $1,494
per person
May 24 - May 30
found 17 hours ago
Roundtrip flight included
Toronto (YYZ) to Houston (IAH)
3/10 (2 reviews)
Hilton Houston North

Hilton Houston North

3.5 out of 5
Northside
Price was CA $1,561, price is now CA $1,264 per person
CA $1,264
per person
Apr 24 - Apr 30
found 10 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to Houston (IAH)
8.2/10 Very Good! (1,011 reviews)
A little hard to reach and the shuttle options were subpar for early AM flights, but comfy rest and friendly staff.

Reviewed on Mar 23, 2026

Landing Furnished Apartments Northwest Houston 

Landing Furnished Apartments Northwest Houston 

3.5 out of 5
Price was CA $1,637, price is now CA $1,335 per person
CA $1,335
per person
May 24 - May 30
found 17 hours ago
Roundtrip flight included
Toronto (YYZ) to Houston (IAH)
No reviews
The Lancaster Hotel

The Lancaster Hotel

4 out of 5
Downtown Houston
Price was CA $4,402, price is now CA $3,592 per person
CA $3,592
per person
Jun 16 - Jun 18
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Houston (IAH)
9.8/10 Exceptional! (1,016 reviews)
We absolutely loved our stay at this hotel! The location was perfect for a weekend getaway, close to everything while still feeling relaxing and comfortable. The property itself was beautiful, very clean, and had great amenities that made our stay even more enjoyable. This would be an ideal spot for an anniversary or special occasion. Everything felt well taken care of and inviting. We also ordered room service, which was delicious, and the breakfast was just as impressive. We will definitely be coming back and would highly recommend it to anyone looking for a relaxing and enjoyable stay.

Reviewed on Mar 22, 2026

Where to stay in Texas Medical Center

Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Discovery Green which includes city views, a square or plaza and a skyscraper

Downtown Houston

3 out of top 10 points of interest in this area
4/5(79 area reviews)

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

Find hotels in Downtown Houston

Texas Medical Center Hotel Deals

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $220 per night from Apr 12 to Apr 13
CA $220
CA $258 total
Apr 12 - Apr 13
includes taxes & fees
9/10 Wonderful! (3,759 reviews)
I love the blossom. The only hotel i will stay everytime im in houston

Reviewed on Mar 24, 2026

Blossom Hotel Houston, Curio Collection by Hilton
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $115 per night from Apr 5 to Apr 6
CA $115
CA $136 total
Apr 5 - Apr 6
includes taxes & fees
8.4/10 Very Good! (1,865 reviews)
Extremely noisy. Starting around 6:00AM there was constant noise. Carts rolling, walkie talkies , loud talking in the halls. Did not get a good night's sleep.

Reviewed on Mar 23, 2026

Hilton Houston Plaza/Medical Center
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
Fully refundable
The price is CA $237 per night from Mar 29 to Mar 30
CA $237
CA $305 total
Mar 29 - Mar 30
includes taxes & fees
9.2/10 Wonderful! (1,008 reviews)
This an excellent hotel. Great for shuttle to NRG Stadium. Had buffet breakfast and it was delicious and restaurant staff was very nice and attentive. Parking garage next to hotel. The elevator takes you directly into the lobby.

Reviewed on Mar 23, 2026

InterContinental Houston by IHG
See all 6,458 properties in Texas Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
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Frequently asked questions

How much does a Texas Medical Center vacation package cost?
Much less than you might think — from only CA $1,043, in fact! By bundling flights, hotels and car rentals into a tailor-made vacation package, your getaway to Texas Medical Center is just a few clicks away.
How do I get a cheap travel package to Texas Medical Center?
Browse and lock in everything in the one place with our Texas Medical Center vacation packages. You'll discover bargains on flights, hotels, tours and more that'll keep your hip pocket happy and your adventurous spirit alive. And, with more than 550 airlines and 1,000,000 properties all over the world to select from, you'll have the flexibility to mix and match as you please.
Where should I stay in Texas Medical Center?
Choose a place close to Houston Zoo. This famous sight is in the middle of the action and on the must-see lists of many travelers.
What are the top hotels in Texas Medical Center?
Hilton Garden Inn Houston Medical Center, TX and Home2 Suites by Hilton Houston Medical Center, TX are two of the most well-known hotels in Texas Medical Center. Why not have a look at the rates and amenities at each and then decide?
How far in advance should I book my Texas Medical Center vacation?
Browse Expedia to compare international flights as soon as you know your travel dates. You can normally purchase a ticket up to a year in advance. If it's too early for your preferred air carrier, or you have to book last minute, don't stress. Low prices to Texas Medical Center occasionally appear just weeks before the date of departure.
What does an Expedia Texas Medical Center travel package include?
Expedia has all you need to lock in Texas Medical Center trip, but how your package is structured is your choice. Choose from a combination of rental cars, flights and hotels. In search of a few activities to keep you busy? Once you've made your booking, you can add them too. Whatever your style or budget, there's a package deal to match your needs.
What should I know before booking a Texas Medical Center travel package?
Our prices are already low. However, you'll snap up even more savings when you book your flights, hotels and car rentals together. With an Expedia travel package, you'll get transparent pricing and a terrific range of choice.
Can I choose my airline with a Texas Medical Center Expedia vacation package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines around the world. Our packages give you the flexibility to pick from available flights, hotels and activities that fit your needs.
If I'm not able to travel, can I cancel my Texas Medical Center vacation package?
It's difficult to predict what tomorrow might bring, so it's good to know that you can change or cancel your Texas Medical Center vacation package. If you made your booking in the last 24 hours, you may be eligible for a refund. If your booking is older, your airline, hotel or car rental company may charge a fee. Check our Customer Service Portal to learn more.

Discover the most popular places to visit in Texas Medical Center

MD Anderson Cancer Center

Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.

MD Anderson Cancer Center

Things to do

Astroville Tunnel Tour of Downtown Houston

Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)

CA $34
per adult
100% of travellers recommend
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
Houston: Sloomoo Institute Entry Ticket

Houston: Sloomoo Institute Entry Ticket

CA $44
per adult
Houston: Sloomoo Institute Entry Ticket
See all activities in Houston
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.