Title: South San Francisco Vacation Packages & Trips 2026 from CA $550 | Expedia.ca

[South San Francisco Travel Guide](https://expedia.ca/South-San-Francisco.dx6773)[Hotels in South San Francisco](https://expedia.ca/South-San-Francisco-Hotels.d6773.Travel-Guide-Hotels)[Vacation Rentals in South San Francisco](https://expedia.ca/South-San-Francisco-Vacation-Rentals.d6773.Travel-Guide-VacationRentals)[Flights to South San Francisco](https://expedia.ca/Cheap-Flights-To-South-San-Francisco.d6773.Travel-Guide-Flights)[Things to do in South San Francisco](https://expedia.ca/Things-To-Do-In-South-San-Francisco.d6773.Travel-Guide-Activities)[South San Francisco Car Rentals](https://expedia.ca/Car-Rentals-In-South-San-Francisco.d6773.Car-Rental-Guide)

![](https://images.trvl-media.com/place/6773/e0ac7e69-5f84-4bd7-a20d-64d74e0ce372.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# South San Francisco Vacation Packages

## Book a Hotel + Flight or Car together to unlock savings

- ##  
Plan, book, travel with confidence
- ###  
Better together  
Save up to CA $1,096 when you book a flight and hotel together\*
- ###  
Find the right fit  
With over 300,000 hotels worldwide, it's easy to create a perfect package
- ###  
Rest easy  
Plan, book, and manage your trip all in one place

#### Your South San Francisco Vacation

Lock in a South San Francisco vacation package and get ready to experience the best of this lively city. Consider basing yourself in the neighborhood of Sharp Park, which is great for families, nature and golfing. Make your trip to South San Francisco even more fun by including some sightseeing. [San Francisco State University](https://www.expedia.ca/San-Francisco-State-University-Lakeshore.d502583.Vacation-Attraction), [Cow Palace](https://www.expedia.ca/Cow-Palace-San-Francisco.d502571.Vacation-Attraction) and [Pacifica State Beach](https://www.expedia.ca/Pacifica-State-Beach-Linda-Mar.d6151598.Vacation-Attraction) are among the major attractions worth exploring. Browse Expedia's wide range of travel options and start organizing your ideal vacation to South San Francisco now.

## Top South San Francisco Vacation Deals

Price found within the past 48 hours. Click for updated prices.

![Hotel Riu Plaza Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Riu Plaza Fisherman's Wharf

Fisherman's Wharf

CA $550

per person

Mar 6 - Mar 9

found 13 hours ago

Roundtrip non-stop flight included

Edmonton (YEG) to San Francisco (SFO)

9/10 Wonderful! (7,092 reviews)

Everything fantastic

Reviewed on Dec 23, 2025

![1 Hotel San Francisco](https://images.trvl-media.com/lodging/2000000/1140000/1138300/1138217/60488ea7_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### 1 Hotel San Francisco

Downtown San Francisco

CA $2,886

per person

Feb 28 - Mar 6

found 1 day ago

Roundtrip non-stop flight included

Montreal (YUL) to San Francisco (SFO)

9.2/10 Wonderful! (470 reviews)

The staff was incredible and we loved all of the design touches in the room. The attention to detail was impressive.

Reviewed on Dec 7, 2025

![Treehouse Hotel Silicon Valley](https://images.trvl-media.com/lodging/1000000/30000/22600/22537/7b11e84d_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Treehouse Hotel Silicon Valley

CA $4,816

per person

Feb 5 - Feb 9

found 17 hours ago

Roundtrip flight included

Toronto (YYZ) to San Francisco (SFO)

9.6/10 Exceptional! (59 reviews)

Love this hotel! Beautiful rooms, super comfy bed, great restaurant! It’s all I need 😃😃😃

Reviewed on Dec 19, 2025

![Hotel Zeppelin San Francisco](https://images.trvl-media.com/lodging/1000000/10000/5900/5875/086bfcbb_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Zeppelin San Francisco

Union Square

CA $1,380

per person

Mar 5 - Mar 11

found 19 hours ago

Roundtrip flight included

Vancouver (YVR) to San Francisco (SFO)

8.6/10 Excellent! (1,001 reviews)

Perfect location. Everything was great

Reviewed on Dec 18, 2025

![The Phoenix Hotel](https://images.trvl-media.com/lodging/1000000/20000/14500/14420/e9262ac5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### The Phoenix Hotel

Downtown San Francisco

CA $576

per person

Mar 6 - Mar 9

found 13 hours ago

Roundtrip non-stop flight included

Edmonton (YEG) to San Francisco (SFO)

9/10 Wonderful! (1,004 reviews)

The front desk staff both AM and PM were sooo amazing! The ambiance is SO FUN, the rooms are modest but the pillows were so comfy and the linens were fresh and clean. We didn't gumb much time in the room since we were in the city to have fun!! Every staff member was so Helpful, Accomodating and great warm personalities. Thank you !!!

Reviewed on Dec 20, 2025

## Ready to book your vacation to South San Francisco?

Choose your dates

## South San Francisco Hotel Deals

![Travelodge by Wyndham San Francisco Airport North](https://images.trvl-media.com/lodging/1000000/20000/17000/16955/864c4988_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Travelodge by Wyndham San Francisco Airport North

326 S Airport Blvd South San Francisco CA

Fully refundableReserve now, pay when you stay

CA $80

CA $96 total

Dec 25 - Dec 26

includes taxes & fees

5.8/10 (2,955 reviews)

Friendly staff, quick check in, room was clean, good ammenities,

Reviewed on Dec 21, 2025

[](https://expedia.ca/Hotel-Search?startDate=25%2F12%2F2025&endDate=26%2F12%2F2025&selected=16955&PinnedHotelID=16955&HadPinnedHotel=true&regionId=6773)

![Best Western Plus Grosvenor Airport Hotel](https://images.trvl-media.com/lodging/1000000/10000/7700/7635/062e9dfe_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Best Western Plus Grosvenor Airport Hotel

380 S Airport Boulevard South San Francisco CA

Fully refundableReserve now, pay when you stay

CA $131

CA $154 total

Dec 24 - Dec 25

includes taxes & fees

8.4/10 Very Good! (1,698 reviews)

Totally enjoyed our stay. The bar and breakfast were an added treat. Great location for travelers.

Reviewed on Dec 18, 2025

[](https://expedia.ca/Hotel-Search?startDate=24%2F12%2F2025&endDate=25%2F12%2F2025&selected=7635&PinnedHotelID=7635&HadPinnedHotel=true&regionId=6773)

![Sonesta Select San Francisco Airport Oyster Point Waterfront](https://images.trvl-media.com/lodging/1000000/550000/548400/548380/0a287fc7_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Sonesta Select San Francisco Airport Oyster Point Waterfront

1300 Veterans Blvd South San Francisco CA

Fully refundableReserve now, pay when you stay

CA $136

CA $163 total

Jan 4 - Jan 5, 2026

includes taxes & fees

8.6/10 Excellent! (1,904 reviews)

clean room and friendly staff

Reviewed on Dec 18, 2025

[](https://expedia.ca/Hotel-Search?startDate=04%2F01%2F2026&endDate=05%2F01%2F2026&selected=548380&PinnedHotelID=548380&HadPinnedHotel=true&regionId=6773)

[See all 5,133 properties in South San Francisco](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=24%2F12%2F2025&endDate=25%2F12%2F2025&regionId=6773)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

All Inclusive Vacations

[](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Beach Vacations

[](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Family Vacations

[](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Golf Vacations

[](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Luxury Vacations

[](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Romantic Vacations

[](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Ski Vacations

[](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click)

### Discover the most popular places to visit in South San Francisco

![Golden Gate Bridge showing a suspension bridge or treetop walkway, a marina and a bay or harbour](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22315-Golden-Gate-Bridge.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Golden Gate Bridge

Cars trundle across it and ships sail under it, but the best way to experience this iconic bridge is on foot.

[](https://expedia.ca/Golden-Gate-Bridge-San-Francisco.d508803.Vacation-Attraction)

![Pier 39 showing signage, street scenes and a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22340-Pier-39.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Pier 39

This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.

[](https://expedia.ca/Pier-39-Fishermans-Wharf.d502576.Vacation-Attraction)

![Golden Gate Park featuring flowers and a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/25000/25240-Golden-Gate-Park.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Golden Gate Park

This beloved park offers relaxation among trees, flowers and wildlife, right in San Francisco’s backyard.

[](https://expedia.ca/Golden-Gate-Park-Golden-Gate.d507464.Vacation-Attraction)

### What to do in South San Francisco

![California Academy of Sciences General Admission](https://mediaim.expedia.com/localexpert/219652/f0bca80b-682f-4287-bac0-eccb47dd5591.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### California Academy of Sciences Daytime Admission

CA $68

per adult

**86%** of travellers recommend

[](https://expedia.ca/things-to-do/california-academy-of-sciences-daytime-admission.a219652.activity-details)

![Go City: San Francisco All-Inclusive Pass with 25+ Attractions](https://mediaim.expedia.com/localexpert/219896/8f48853e-8b87-4e6b-85c2-057f6b4e921c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Go City: San Francisco All-Inclusive Pass with 30+ Attractions

CA $143

per adult

**88%** of travellers recommend

[](https://expedia.ca/things-to-do/go-city-san-francisco-all-inclusive-pass-with-30-attractions.a219896.activity-details)

![Visit de Young Museum in Golden Gate Park](https://mediaim.expedia.com/localexpert/852149/5f951497-8465-48c2-bf9a-eff985a5464e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### de Young Museum General Admission Ticket

CA $28

per adult

**88%** of travellers recommend

[](https://expedia.ca/things-to-do/de-young-museum-general-admission-ticket.a852149.activity-details)

[See all activities in South San Francisco](https://expedia.ca/things-to-do/search?rid=6773)

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- [Flights from Edmonton (YEG) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yeg/sfo/edmonton-to-san-francisco)
- [Flights from Ottawa (YOW) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yow/sfo/ottawa-to-san-francisco)
- [Flights from Montreal (YUL) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yul/sfo/montreal-to-san-francisco)
- [Flights from Vancouver (YVR) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yvr/sfo/vancouver-to-san-francisco)
- [Flights from Winnipeg (YWG) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/ywg/sfo/winnipeg-to-san-francisco)
- [Flights from Calgary (YYC) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yyc/sfo/calgary-to-san-francisco)
- [Flights from Toronto (YYZ) to San Francisco (SFO) ](https://www.expedia.ca/lp/flights/yyz/sfo/toronto-to-san-francisco)

- [Bayfront Park ](https://www.expedia.ca/Bayfront-Park-San-Francisco.d553248621579088854.Vacation-Attraction)
- [Bill Graham Civic Auditorium ](https://www.expedia.ca/Bill-Graham-Civic-Auditorium-Downtown-San-Francisco.d6155057.Vacation-Attraction)
- [Brisbane Vacations ](https://www.expedia.ca/Brisbane.d602634.Destination-Travel-Guides)
- [California Academy of Sciences ](https://www.expedia.ca/California-Academy-Of-Sciences-Golden-Gate.d6151535.Vacation-Attraction)
- [California State Building ](https://www.expedia.ca/California-State-Building-Downtown-San-Francisco.d6177654.Vacation-Attraction)
- [Chase Center ](https://www.expedia.ca/Chase-Center-Downtown-San-Francisco.d553248635997928290.Vacation-Attraction)
- [Conservatory of Flowers ](https://www.expedia.ca/Conservatory-Of-Flowers-Golden-Gate.d6069419.Vacation-Attraction)
- [Coyote Point Park ](https://www.expedia.ca/Coyote-Point-Park-Shoreview.d6227859.Vacation-Attraction)
- [Crystal Springs Golf Course ](https://www.expedia.ca/Crystal-Springs-Golf-Course-Burlingame.d6131176.Vacation-Attraction)
- [De Young Museum ](https://www.expedia.ca/De-Young-Museum-Golden-Gate.d6063203.Vacation-Attraction)
- [Golden Gate Park ](https://www.expedia.ca/Golden-Gate-Park-Golden-Gate.d507464.Vacation-Attraction)
- [Haight Street ](https://www.expedia.ca/Haight-Street-Haight-Ashbury.d553248621533113893.Vacation-Attraction)
- [Japanese Tea Garden ](https://www.expedia.ca/Japanese-Tea-Garden-Golden-Gate.d6063205.Vacation-Attraction)
- [John McLaren Park ](https://www.expedia.ca/John-McLaren-Park-Visitacion-Valley.d6155210.Vacation-Attraction)
- [Millbrae Square Shopping Center ](https://www.expedia.ca/Millbrae-Square-Shopping-Center-San-Francisco.d6161259.Vacation-Attraction)
- [Mission Dolores Park ](https://www.expedia.ca/Mission-Dolores-Park-Mission-District.d6227863.Vacation-Attraction)
- [Mission San Francisco de Asís ](https://www.expedia.ca/Mission-San-Francisco-De-Asis-Mission-District.d553248634285122123.Vacation-Attraction)
- [Oracle Park ](https://www.expedia.ca/Oracle-Park-Downtown-San-Francisco.d6063199.Vacation-Attraction)
- [Pacifica Vacations ](https://www.expedia.ca/Pacifica.d9065.Destination-Travel-Guides)
- [Rockaway Beach ](https://www.expedia.ca/Rockaway-Beach-Rockaway-Beach.d6151600.Vacation-Attraction)
- [Sfjazz Center ](https://www.expedia.ca/SFJAZZ-Center-Civic-Center.d6265863.Vacation-Attraction)
- [San Bruno Vacations ](https://www.expedia.ca/San-Bruno.d6633.Destination-Travel-Guides)
- [San Francisco City Hall ](https://www.expedia.ca/San-Francisco-City-Hall-Downtown-San-Francisco.d502549.Vacation-Attraction)
- [Visit Paradise Valley ](https://www.expedia.ca/San-Francisco-Paradise-Valley.dx553248635976473811)
- [San Francisco State University ](https://www.expedia.ca/San-Francisco-State-University-Lakeshore.d502583.Vacation-Attraction)
- [San Francisco Vacations ](https://www.expedia.ca/San-Francisco.d178305.Destination-Travel-Guides)
- [San Mateo Vacations ](https://www.expedia.ca/San-Mateo.d6653.Destination-Travel-Guides)
- [Shoreview Park ](https://www.expedia.ca/Shoreview-Park-East-San-Mateo.d553248634966110229.Vacation-Attraction)
- [The Promenade ](https://www.expedia.ca/The-Promenade-Downtown-San-Francisco.d553248621555612166.Vacation-Attraction)
- [Twin Peaks ](https://www.expedia.ca/Twin-Peaks-Eureka-Valley.d502560.Vacation-Attraction)
- [Van Ness Avenue ](https://www.expedia.ca/Van-Ness-Avenue-Downtown-San-Francisco.d3000663410.Vacation-Attraction)

- [Car rentals near SFO Museum ](https://www.expedia.ca/Car-Rentals-In-SFO-Museum.d553248621555611878.Car-Rental-Guide)
- [Rental cars San Francisco Intl. airport ](https://www.expedia.ca/Car-Rentals-In-San-Francisco-Intl.d5195347.Car-Rental-Guide)

- [Things to do in San Bruno ](https://www.expedia.ca/Things-To-Do-In-San-Bruno.d6633.Travel-Guide-Activities)

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

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