Title: Browse the Best South Carolina Midlands Resorts | Expedia.ca [South Carolina Midlands Travel Guide](https://expedia.ca/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Vacation Rentals in South Carolina Midlands](https://expedia.ca/South-Carolina-Midlands-Vacation-Rentals.d6057938.Travel-Guide-VacationRentals)[Flights to South Carolina Midlands](https://expedia.ca/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[South Carolina Midlands Car Rentals](https://expedia.ca/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.ca/South-Carolina-Midlands.d6057938.Destination-Travel-Guides) ![South Carolina State House](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/183000/183997-State-House.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Resort Hotels in South Carolina Midlands ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-10-03&endDate=2025-10-05&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-10-10&endDate=2025-10-12&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-10-24&endDate=2025-10-26&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6057938&startDate=2025-11-21&endDate=2025-11-23&adults=2&lodging=HOTEL_RESORT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select South Carolina Midlands Resorts ![Pool](https://images.trvl-media.com/lodging/103000000/102020000/102018300/102018216/fb378afa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/103000000/102020000/102018300/102018216/bf38ce1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/103000000/102020000/102018300/102018216/d8195f71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/103000000/102020000/102018300/102018216/d9cffe18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront Condo on Lake Marion Santee 10/10 Exceptional (6) "This place was outstanding, clean and beautifully decorated. I will rent this property again " [](https://www.expedia.ca/Santee-Hotels-Spacious-Condo-On-Beautiful-Lake-Marion.h102018216.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/109000000/108970000/108962500/108962490/5692bed0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/109000000/108970000/108962500/108962490/bca2cf62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2Bed/2Bath Deluxe at Lake Marion! Santee [](https://www.expedia.ca/Santee-Hotels-2Bed2Bath-Deluxe-At-Lake-Marion.h108962490.Hotel-Information) ![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/109000000/108970000/108963200/108963171/6008f4d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3Bed/3Bath Deluxe at Lake Marion! Santee [](https://www.expedia.ca/Santee-Hotels-3Bed3Bath-Deluxe-At-Lake-Marion.h108963171.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/109000000/108970000/108963600/108963596/b1937017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/109000000/108970000/108963600/108963596/62c27d79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Marion 2Bed/2Bath Deluxe! Santee [](https://www.expedia.ca/Santee-Hotels-Lake-Marion-2Bed2Bath-Deluxe.h108963596.Hotel-Information) ![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/109000000/108970000/108964200/108964119/bcd8bf6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Marion 3Bed/3Bath Deluxe! Santee [](https://www.expedia.ca/Santee-Hotels-Lake-Marion-3Bed3Bath-Deluxe.h108964119.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-12&endDate=2025-10-13®ionId=6057938&adults=2&lodging=HOTEL_RESORT&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Resort-Hotels.d6057938-aaResortHotels.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Resort-Hotels.d6057938-aaResortHotels.Travel-Guide-Accommodation) ## Top South Carolina Midlands Hotel Reviews ![Country Inn & Suites by Radisson, Columbia, SC](//images.trvl-media.com/lodging/1000000/210000/202900/202867/04e820c9_y.jpg) ### Country Inn & Suites by Radisson, Columbia, SC 10/10 Excellent "The room was clean but tired." [](https://expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h202867.Hotel-Information) ![Park Inn by Radisson Florence, SC](//images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg) ### Park Inn by Radisson Florence, SC 10/10 Excellent "The breakfast was amazing nice options. Lobby was Beautifull, The rooms were very cozy and clean . sthe bed was very very soft! my 5 year old said He slept great!! We absolutely loved our stay!" [](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Wyndham Garden Columbia/Ft. Jackson](//images.trvl-media.com/lodging/78000000/77820000/77814700/77814689/e6cbdb45_y.jpg) ### Wyndham Garden Columbia/Ft. Jackson 10/10 Excellent "Room was big and spacious, clean, and room service was great. The morning breakfast was so good and hot as well as plentiful. I only wish that breakfast would end at 10am and not 9am. But this was an awesome experience for my family and I." [](https://expedia.ca/Columbia-Hotels-Hotel-Columbia-Inn-Suites.h77814689.Hotel-Information) ![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](//images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg) ### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG 10/10 Excellent "Clean, nice and very well maintained " [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Suites-Columbia-I-26-Harbison-Blvd.h688607.Hotel-Information) ![ La Quinta Inn by Wyndham Columbia NE/Fort Jackson](//images.trvl-media.com/lodging/1000000/50000/43600/43541/ebebcc50_y.jpg) ### La Quinta Inn by Wyndham Columbia NE/Fort Jackson 10/10 Excellent "Just beautiful experience for me & my dad. " [](https://expedia.ca/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia-NE-Fort-Jackson.h43541.Hotel-Information) ![Cambria Hotel Columbia Downtown The Vista](//images.trvl-media.com/lodging/77000000/76600000/76599300/76599223/e2b9c83a_y.jpg) ### Cambria Hotel Columbia Downtown The Vista 10/10 Excellent "Very clean and smells good. " [](https://expedia.ca/Columbia-Hotels-Cambria-Hotel-Columbia-Downtown-The-Vista.h76599223.Hotel-Information) ![Tru By Hilton Columbia Downtown](//images.trvl-media.com/lodging/111000000/110650000/110648500/110648494/w3840h2557x0y3-1e9d91e1_y.jpg) ### Tru By Hilton Columbia Downtown 10/10 Excellent "Very clean rooms- property looks brand new " [](https://expedia.ca/Columbia-Hotels-Tru-By-Hilton-Columbia-Downtown.h110648494.Hotel-Information) ![Sleep Inn Near Ft Jackson](//images.trvl-media.com/lodging/1000000/130000/120500/120428/f4f5ae62_y.jpg) ### Sleep Inn Near Ft Jackson 10/10 Excellent "I was pleased they offer affordable prices. " [](https://expedia.ca/Columbia-Hotels-Sleep-Inn-Near-Ft-Jackson.h120428.Hotel-Information) ![Hilton Garden Inn Columbia/Harbison](//images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9_y.jpg) ### Hilton Garden Inn Columbia/Harbison 10/10 Excellent "Enjoyed the jetted tub in my room. Hallway was noisy with people walking by and talking outside their rooms though. " [](https://expedia.ca/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ## Find out more about South Carolina Midlands ## South Carolina Midlands Resorts information | Number of reviews | 5 | | --- | --- | | Accommodation | 4 Resorts | | Lowest Price | | | Highest Price | | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Hotels near Allen University](https://www.expedia.ca/Allen-University-Hotels.0-l6245638-0.Travel-Guide-Filter-Hotels) - [B&B in Arcadia Lakes](https://www.expedia.ca/Arcadia-Lakes-Bed-And-Breakfast.d553248634998974994-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Arcadia Lakes](https://www.expedia.ca/Arcadia-Lakes-Guest-Houses.d553248634998974994-aaGuestHouses.Travel-Guide-Accommodation) - [Arcadia Lakes Hotels](https://www.expedia.ca/Arcadia-Lakes-Hotels.d553248634998974994.Travel-Guide-Hotels) - [Inns in Arcadia Lakes](https://www.expedia.ca/Arcadia-Lakes-Inns.d553248634998974994-aaInns.Travel-Guide-Accommodation) - 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