Find Spa Hotels in Seneca, SC from CA $125

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Recommended hotels in Seneca

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Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (58 reviews)
"Excellent stay."
United States
Beonca
The price is CA $94
CA $163 total
includes taxes & fees
Feb 17 - Feb 18
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Free daily on-the-go breakfast

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (677 reviews)
"Everting was good"
United States
Susan
The price is CA $106
CA $125 total
includes taxes & fees
Feb 22 - Feb 23
Quality Inn Seneca Clemson Area US-123
Exterior

Cozy Clemson TIny House Cabin

Cozy Clemson TIny House Cabin
Seneca
The price is CA $170
CA $297 total
includes taxes & fees
Feb 22 - Feb 23
Cozy Clemson TIny House Cabin
Property amenity

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (207 reviews)
"Spotless, friendly staff, great location. "
United States
Cari
The price is CA $170
CA $187 total
includes taxes & fees
Feb 22 - Feb 23
Fairfield Inn & Suites Seneca Clemson Univ Area
Aerial view

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,002 reviews)
"Great place and location, great mattress, "
United States
Jeffrey
The price is CA $148
CA $184 total
includes taxes & fees
Feb 17 - Feb 18
Lakeside Lodge Clemson
Private kitchen

The Clemson Cottage - 3.6 mi. to Memorial Stadium

The Clemson Cottage - 3.6 mi. to Memorial Stadium
Seneca
10.0 out of 10, Exceptional, (12 reviews)
"Adorable and clean home convenient to Clemson’s campus. We enjoyed our stay and Tyler was an exceptional host! "
United States
Mandy H.
The price is CA $245
CA $533 total
includes taxes & fees
Feb 17 - Feb 18
The Clemson Cottage - 3.6 mi. to Memorial Stadium
1 bedroom, iron/ironing board, WiFi, bed sheets

Boutique hotel in historic downtown Seneca. Room #5, two King beds.

Boutique hotel in historic downtown Seneca. Room #5, two King beds.
Downtown
9.6 out of 10, Exceptional, (15 reviews)
"We had a wonderful visit- clean and beautifully decorated. It was a little bit unusual to not have a window but very nice stay. "
United States
Rachel L.
The price is CA $163
CA $267 total
includes taxes & fees
Feb 17 - Feb 18
Boutique hotel in historic downtown Seneca. Room #5, two King beds.
1 bedroom, WiFi, bed sheets

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Seneca
10.0 out of 10, Exceptional, (12 reviews)
"Very clean and comfortable - very close to Clemson and easy access. "
United States
Jim A.
The price is CA $204
CA $271 total
includes taxes & fees
Feb 17 - Feb 18
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Reception

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (680 reviews)
"Everything was excellent "
United States
Debby
The price is CA $168
CA $185 total
includes taxes & fees
Feb 22 - Feb 23
Hampton Inn & Suites Seneca-Clemson Area
1 bedroom, iron/ironing board, WiFi, bed sheets

Private Room #3

Private Room #3
Downtown
9.2 out of 10, Wonderful, (13 reviews)
"Very clean and comfortable! Will stay again!"
United States
Joseph K.
The price is CA $163
CA $267 total
includes taxes & fees
Feb 17 - Feb 18
Private Room #3
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent
"Woman at the front desk "
Michael 1-night trip
Posted 3 weeks ago
Hampton Inn & Suites Seneca-Clemson Area

Frequently asked questions

How much does a spa hotel in Seneca cost?
Enjoy staying in a spa hotel in Seneca, with plenty of hotels from CA $125 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays.
Is it cheaper to book a spa hotel in Seneca with flights as part of a package deal?
Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package.
Are there any unique spa experiences available in Seneca?
Yes, Seneca, South Carolina offers several unique spa experiences, particularly through specialised aesthetic and wellness clinics.

Jocassee Hydration & Aesthetics in downtown Seneca provides advanced treatments such as facial fillers, microneedling with platelet rich fibrin (PRF), and natural facial treatments. They also offer an "Eye of the Tiger intravenous therapy" designed to boost energy and mood, a distinctive wellness option.

The Refinery Co., an aesthetic clinic, focuses on advanced skin care procedures including chemical peels, diamond dermabrasion facials, and hydrofacials. Their approach combines personalised care with modern technology for a unique medspa experience.

Tony Massage & Salon, LLC and Your Contoured Body also contribute to the local wellness scene, offering massage and body contouring services respectively.
How can I save on a spa hotel in Seneca with Expedia?
Members always get our best prices. Find our best Seneca spa hotel deals by joining Expedia's free travel rewards program—One Key™. As a member, you can unlock instant savings and member perks when you're logged in to your account. For a spontaneous weekend retreat, discover last-minute offers.
Can I cancel my spa hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in Seneca for you.

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