Find Hotels by Independent in Seneca
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Tonight
Sep 15 - Sep 16Tomorrow
Sep 16 - Sep 17This weekend
Sep 18 - Sep 20Next weekend
Sep 25 - Sep 27
Save an average of 15% on thousands of hotels when you're signed in
Top Seneca Hotel Reviews
Fairfield Inn & Suites Seneca Clemson Univ Area
10/10 Excellent
"Awesome hotel! The staff was so nice and the hotel was so clean. Our room was great! And the breakfast was really good as well."
Hampton Inn & Suites Seneca-Clemson Area
10/10 Excellent
"Friendly and convenient hotel that I keep returning to every year for business travel."
Best Western Seneca-Clemson
8/10 Good
"Na"
Quality Inn Seneca US-123
8/10 Good
"Parking was difficult but manageable"
4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!
10/10 Excellent
"Beautiful view. Plenty of room. Deep water at dock. Well-stocked with kitchen tools/utensils."
Charming and Entertaining Lake House Retreat for Large Groups!
10/10 Excellent
"We arrived to a clean home. Comfortable beds and stocked kitchen. The host was very accommodating and responded quickly to questions before we arrived. Everything we expected was there. I would definitely book this property again as my daughter lives in Seneca."
Days Inn by Wyndham Seneca / Clemson Area
8/10 Good
"Decent if you’re just looking for a place to sleep. Breakfast wasn’t bad, just limited options. Room was fairly clean (didn’t look like it had been mopped) . But sheets/blankets/towels were super clean!"
Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water
10/10 Excellent
"We came for some much needed R and R!! This was great and very peaceful. The beds were very comfortable. The house location was private but close to amenities."
Beautiful large family home with dock on Lake Keowee!
10/10 Excellent
"Perfect space for a group needing 7 individual bedrooms. The kitchen had plenty of space for food prep and the home has 2 refrigerators. There was plenty of seating for all of us in the main living area and additional space on both the basement level and 2nd floor. We enjoyed peaceful mornings on the porch and peaceful evenings by the dock. The dock fit our Tritoon and was covered. The dock is in good shape and the decks look like flooring has recently been replaced. The house is in a quiet neighborhood and the next time we get together with a large group, this is the first place we will try to rent."
Explore a world of travel with Expedia
- Misty Lake Lodge
- Marriott Hotels & Resorts in Westminster
- Six Mile Hotels
- Hotels near Lake Keowee
- North Forty Family Friendly Home
- Red Roof Inn Hotels in Easley
- Hotels near Lake Jocassee
- Westminster Hotels
- Cabin Rentals in Anderson
- Greenville Hotels
- Clemson Condo for Your Gameday Getaway!
- Hotels near Clemson University
- Marriott Hotels & Resorts in Landrum
- Southern Sunshine Retreat
- Guest Houses in Easley
- Pelzer Hotels
- The Jocassee Tiny House
- Tru by Hilton Seneca Clemson
- Hotels with Kitchenettes in Welcome
- Value Place Hotels in Duncan
- Lake Keowee retreat for 10 with private dock!
- Cabin Rentals in Walhalla
- Red Roof Inn Hotels in Seneca
- Peaceful Mountain Home
- Serene Getaway
- The Point RV
- Central Hotels
- Lakefront home with private beach & unbelievable sunsets on Lake Keowee
- Motel 6 Hotels in Duncan
- Hotels with Hot Tubs in Anderson
- Resorts in Easley
- Shopping Hotels in Seneca
- 4br Luxury Lakefront, big view, Private boatslip, pool table, 15 min Clemson!
- Piedmont Hotels
- Lgbt Friendly Hotels in Seneca
- Henry’s red roof cabin on the Chauga River
- Robinson Lake Front Lodge on Lake Jocassee
- River Haven
- Massive Lake Keowee Knox Campground Cabin
- Beach Hotel Hotels in Oconee County
- Hilton Hotels in Iva
- Anderson Hotels
- Lake Retreat House
- Hampton Inn Clemson
- Salem Hotels
- Cozy Pet Friendly Cottage
- Rv Parks in Easley
- Hotels near Anderson County Regional
- Rv Parks in Williamston
- Clemson Hotels
- The Abernathy of Clemson
- The Inn at Patrick Square
- Cottages in Rocky Bottom
- Marriott Hotels & Resorts in Welcome
- Hampton Inn Anderson/ Alliance Business Park
- Accor Hotels in Greenville
- Hotels near Memorial Stadium
- Lake Hartwell 4BR Waterfront Hot Tub GameRoom
- Long Creek Hotels
- Cottages in Welcome
- Hotels with Kitchenettes in Seneca
- B&B in Anderson
- Quality Inn Seneca Clemson Area US
- Pumpkintown Hotels
- Flights to Clemson
- Flights from Vancouver (YVR) to Anderson (AND)
- Flights from Toronto (YYZ) to Greenville (GSP)
- Flights from Montreal (YMQ) to Anderson (AND)
- Flights from Buffalo (BUF) to Clemson (CEU)
- Flights from Six Mile
- Flights to Pickens
- Flights to Easley
- Flights to Greenville - Spartanburg
- Flights to Fair Play
- Flights from Seneca
- Flights from Toronto (YYZ) to Anderson (AND)
- Flights to Anderson
- Flights from Belton
- Flights to Seneca
- Flights from Boston (BOS) to Pickens (LQK)
- Flights from Anderson
- Flights from Manchester (MAN) to Clemson (CEU)
- Flights from Asheville (AVL) to Clemson (CEU)
- Flights to Liberty
- Flights from Los Angeles (LAX) to Clemson (CEU)
- Flights from Burbank (BUR) to Anderson (AND)
- Flights from Detroit (DTW) to Pickens (LQK)