Santana Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

Photo by Fabrice Récalt
  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Santana Vacation

Art, food, entertainment and more … There's so much to experience with a Santana vacation package. And with the ability to easily customize your city adventure, it's guaranteed to be one you won't forget. When it's time to venture out and explore, be sure to put Cathedral of São Tomé and Estadio Nacional 12 de Julho on the to-do list for your trip to Santana. Your ideal Santana vacation is a couple of clicks away. Explore accommodations, flights and more on Expedia for a getaway that's tailored just for you.

Top Santana Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Praia Inhame Eco-Lodge

Praia Inhame Eco-Lodge

CA $1,235
per person
Nov 22 - Nov 25
found 22 hours ago
Roundtrip flight included
Accra Intl. Airport (ACC) to São Tomé Island (TMS)
8.8/10 Excellent! (27 reviews)
We had a great stay at Inhame. After a rather scary drive down south through fog, rain, potholes wet palm plantations at dusk, the lodge’s sign of entering a stress-free zone was only too welcome. Rides to the Ilha Rolas and the walk to Praia Vanha arranged easily. Rhe breakfast excellent and all very clean.

Reviewed on Jul 31, 2023

Alojamento Santos Silva

Alojamento Santos Silva

CA $1,706
per person
Nov 22 - Nov 25
found 22 hours ago
Roundtrip flight included
Accra Intl. Airport (ACC) to São Tomé Island (TMS)
No reviews
Hotel Praia

Hotel Praia

CA $1,443
per person
Nov 22 - Nov 25
found 22 hours ago
Roundtrip flight included
Accra Intl. Airport (ACC) to São Tomé Island (TMS)
7.4/10 Good! (18 reviews)
Roça Santo António Ecolodge Hotel

Roça Santo António Ecolodge Hotel

CA $1,265
per person
Nov 22 - Nov 25
found 22 hours ago
Roundtrip flight included
Accra Intl. Airport (ACC) to São Tomé Island (TMS)
8.4/10 Very good! (15 reviews)
This is a wonderful place to stay. I loved room #1!

Reviewed on Apr 23, 2022

Pestana São Tomé

Pestana São Tomé

Vila Maria
CA $1,471
per person
Nov 22 - Nov 25
found 22 hours ago
Roundtrip flight included
Accra Intl. Airport (ACC) to São Tomé Island (TMS)
8.2/10 Very good! (83 reviews)

Ready to book your vacation to Santana?

Choose your dates

Santana Hotel Deals

Roça Santo António Ecolodge Hotel

Roça Santo António Ecolodge Hotel

Roça Santo Antonio Santana
CA $149
CA $302 total
Nov 3 - Nov 4
includes taxes & fees
8.4/10 Very good! (15 reviews)
"This is a wonderful place to stay. I loved room #1!"

Reviewed on Apr 23, 2022

Roça Santo António Ecolodge Hotel
Sea House

Sea House

Santana Cantagalo
Sea House
Pool and Beach Villa in Santana

Pool and Beach Villa in Santana

Estrada brasil Roca Uba Budo Praia Santana São Tomé
Pool and Beach Villa in Santana
See all 54 properties in Santana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in Santana

sipson tours stp

sipson tours stp

CA $137
per adult
sipson tours stp
Lagoa Azul beach

South Rote Sao Tome - A trip not to forget

CA $185
per adult
South Rote Sao Tome - A trip not to forget
Private Tour On São Tomé Island

Private Tour On São Tomé Island

CA $193
per adult
Private Tour On São Tomé Island
See all activities in Santana

Frequently asked questions

How much does a Santana vacation package cost?
Offering excellent value package deals from CA $1,235 on Expedia, you'll be pleasantly surprised at how much a vacation to Santana costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Santana?
If you're looking to score a cheap Santana vacation package, consider visiting in March, April and May. You'll generally find better prices on flights and accommodations during these months — ideal for a budget-friendly getaway.
How many days is enough for Santana?
You can easily explore all the leading attractions in Santana in a few days, including the popular Paroquia da Santissima Trindade. If you're after a longer Santana vacation, check out what kind of day tours and activities are available close by.
How to find the best Santana package deals?
Landing a cheap Santana package deal is a breeze with Expedia. After you've entered your destination and preferred dates under our "Packages" tab, set your budget, add a few filters and see what's available. You can tweak your search by "Property class," "Number of bedrooms," "Traveller experience" and more. Sort the results by "Price: low to high" to view the most wallet-friendly Santana package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider travelling on a weekday, when prices are typically lower.
Is it cheaper to book a Santana vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, hotel and flight into one great-value price and enjoy significant savings. You'll typically snag a better deal than booking each component separately. And you'll still get the freedom to create a personalized Santana vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Santana?
If you have your Santana vacation dates confirmed, book as soon as you can to bag some outstanding deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spur-of-the-moment getaways? Our last-minute deals are ideal for impromptu escapes.
How to plan a trip to Santana?
  1. Pick your dates: The things you plan to do in Santana and your preferred season will help you decide when to get away.
  2. Budget wisely: In addition to the price of your accommodations, you should consider other expenses. These include transportation, flights and food. Also, set aside a little extra for unexpected expenses that may come up during your trip to Santana.
  3. Set the duration of your trip: Start by making a list of all the attractions and activities you'd like to experience in Santana. Then, estimate how long you'll need for each, along with any travel time.
  4. Combine your accommodations and airfare: Once you've nailed down your dates and duration, book the ideal Santana vacation package for you.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.