
Santana Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
Photo by Fabrice Récalt
- Plan, book, travel with confidence
- Better togetherSave up to CA $1,096 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Santana Vacation
Art, food, entertainment and more … There's so much to experience with a Santana vacation package. And with the ability to easily customize your city adventure, it's guaranteed to be one you won't forget. When it's time to venture out and explore, be sure to put Cathedral of São Tomé and Estadio Nacional 12 de Julho on the to-do list for your trip to Santana. Your ideal Santana vacation is a couple of clicks away. Explore accommodations, flights and more on Expedia for a getaway that's tailored just for you.
Top Santana Vacation Deals
Price found within the past 48 hours. Click for updated prices.



Hotel Praia
Price was CA $2,891, price is now CA $2,655 per person
CA $2,655
per person
Apr 3 - Apr 10
found 15 hours ago
Roundtrip non-stop flight included
Lisbon (LIS) to São Tomé Island (TMS)
7.4/10 Good! (18 reviews)
Pros: Room is very spacious and clean. Common areas also nice and generally I enjoyed a quiet atmosphere. Staff is nice, food is good.
Cons: They did not honor the complementary airport transfer that is announced on line, they arranged a private taxi that charged me 20 US Dollars (for a 4 minute ride).
The quality of bed linens and towels is not great, they should improve them.
The one day I used the pool, which is big and pretty, the water was not clean.
Reviewed on Dec 6, 2023

Pestana São Tomé
Vila Maria
Price was CA $3,098, price is now CA $2,872 per person
CA $2,872
per person
Apr 3 - Apr 10
found 15 hours ago
Roundtrip non-stop flight included
Lisbon (LIS) to São Tomé Island (TMS)
8/10 Very Good! (78 reviews)
Wonderful stay, great staff, easy, relaxing delightful.
Reviewed on Dec 9, 2025
Santana Hotel Deals


endless horizon - Cozy house in charming Santana with WiFi
Santana Cantagalo
The price is CA $127 per night from Mar 13 to Mar 14
CA $127
CA $203 total
Mar 13 - Mar 14
includes taxes & fees
10/10 Exceptional! (1 review)
Wonderful stay in nature
We really enjoyed our stay at the Endless Horizon. Joao and Alexander were always there to help out with things. We loved the high ceilings and of course the amazing view. The bed was very comfortable and the shower was wonderful; specious and with nice hot water. We would stay there again.
Reviewed on Dec 24, 2024
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.









