Santa María Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Santa María Vacation
Reserve a Santa María vacation package and get set to experience all this lively city has to offer. Consider basing yourself in the neighborhood of Cartagena Walled City, which is good for views, dining and bars and pubs. San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Jaime Moron Stadium are just a few of the many attractions worth checking out during your trip to Santa María. That dream Santa María vacation is clicks away. Browse hotels, airfares and more on Expedia for a getaway that's tailored to suit your travel style.
Top Santa María Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Casa Bali Castillo View Private Pool & R
Pie del Cerro
CA $2,516
per person
Jan 1 - Jan 8
found 1 day ago
Roundtrip non-stop flight included
Montreal (YUL) to Cartagena (CTG)
10/10 Exceptional! (1 review)
Excelente ubicación, buenas instalaciones, en la recepción tanto Omar como la recepcionista fueron muy amables en todo momento.
Reviewed on Feb 17, 2026
Ready to book your vacation to Santa María?
Santa María Hotel Deals
OZ Hotel Collection
6-164 Carrera 2 Cartagena
Fully refundableReserve now, pay when you stay
CA $141
CA $141 total
Oct 26 - Oct 27
Sofitel Barú Cartagena
KM 7 Sector, Porto Nao Cartagena Bolívar
Fully refundableReserve now, pay when you stay
CA $460
CA $460 total
Nov 8 - Nov 9
Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive
Anillo Vial, Km 12, between Manzanillo Cartagena Bolivar
Fully refundableReserve now, pay when you stay
CA $406
CA $406 total
Nov 10 - Nov 11
8.2/10 Very good! (1,000 reviews)
"Maravilloso todo"
Reviewed on Oct 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in Santa María
Cartagena 5 Island Hop Tour: Lunch, Snorkel, Beach Clubs, & More
CA $99
per adult
84% of travellers recommend
Luxury Cartagena Sunset Pirate ship Adventure, Cannon Show&Drinks
CA $78
per adult
88% of travellers recommend
Frequently asked questions
How much does a Santa María vacation package cost?
Offering excellent value package deals from CA $1,527 on Expedia, you'll be surprised at how little a vacation to Santa María costs! Our packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Santa María?
You can usually find lower rates and greater availability in April, September and October. Browse our cheap Santa María vacation packages and you could get some great off-season deals.
How many days is enough for Santa María?
We suggest planning a Santa María vacation for a minimum of 3 days. This gives you enough time to check off major attractions such as Playa Manzanillo and Las Americas International Convention Centre, as well as check out neighbourhoods like Cartagena Walled City and Bocagrande. You could even slot in a day trip (or two) outside of Santa María.
How to find the best Santa María package deals?
Finding a cheap Santa María package deal is a breeze with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, apply a few filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most economical Santa María package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Santa María vacation as a package?
An Expedia vacation package could land you significant savings when compared to booking flights and stays individually. Better still, you can tailor your Santa María getaway to match your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Santa María?
If you've got your Santa María travel dates locked in, book as early as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are great for jetting off on a whim.
How to plan a trip to Santa María?
- Choose your travel dates: What you want to do in Santa Marían and your preferred season can help you decide when to get away.
- Set your budget: Factor in costs such as flights, meals and transportation when working out how much to set aside for your trip to Santa María. Then, select a hotel that suits your budget, whether that's an affordable stay or a high-end retreat.
- Decide how long to go away for: Now that you're up to speed on Santa María, you can work out the perfect length of your break. Create a draft plan and allocate enough time to get through everything on your must-do list.
- Bundle your bookings: With your travel dates in order, you can combine your car rental, hotels, flights and more into a customized Santa María vacation package.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
