
Santa María Vacation Packages
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Your Santa María Vacation
Reserve a Santa María vacation package and get set to experience all this lively city has to offer. Consider basing yourself in the neighborhood of Cartagena Walled City, which is good for views, dining and bars and pubs. San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Jaime Moron Stadium are just a few of the many attractions worth checking out during your trip to Santa María. That dream Santa María vacation is clicks away. Browse hotels, airfares and more on Expedia for a getaway that's tailored to suit your travel style.
Top Santa María Vacation Deals

Hotel Almirante Cartagena - Colombia
Reviewed on Apr 23, 2026

Casa del Arzobispado Hotel
Reviewed on Apr 21, 2026


Cinco Quintas Hotel Boutique
Reviewed on Apr 15, 2026

Hotel Casa Lola Deluxe Gallery
Reviewed on Mar 10, 2026
Santa María Hotel Deals

Hyatt Regency Cartagena
My room wasn’t too clean when I arrived.
Reviewed on Apr 24, 2026

OZ Hotel Collection
Room was great. Staff was great. You will want to uber if you go anywhere but the beach. If you're alone they allow 1 free visitor, you have to pay for more visits.
Reviewed on Apr 23, 2026

InterContinental Cartagena De Indias by IHG
La habitación muy bonita y limpia, mucho espacio para colocar artículos personales, el personal muy atento, comoda y desayuno exquisito, lo que no me gusto que esta en construcción el area de la playa frente al hotel y la vista desde la habitación que pague con vista al mar no fue lo que yo ...
Reviewed on Apr 22, 2026
Discover the most popular places to visit in Santa María

Bocagrande Beach
If a restful vacation is part of your travel plans, Bocagrande Beach might be the perfect place to seek out during your trip to Cartagena. Make time to visit the area's shops, or simply enjoy its top-notch restaurants.

Clock Tower
You can learn about the history of Cartagena when you stop by Clock Tower. Amble around the area's beautiful beaches or seek out the local tours.

San Pedro Claver Church and Convent
After visiting San Pedro Claver Church and Convent, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.
What to do in Santa María

Cartagena Island Hopping: 5-Stop Rosario Islands Tour with Lunch









