
Santa María Vacation Packages
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Your Santa María Vacation
Reserve a Santa María vacation package and get set to experience all this lively city has to offer. Consider basing yourself in the neighborhood of Cartagena Walled City, which is good for views, dining and bars and pubs. San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Jaime Moron Stadium are just a few of the many attractions worth checking out during your trip to Santa María. That dream Santa María vacation is clicks away. Browse hotels, airfares and more on Expedia for a getaway that's tailored to suit your travel style.
Top Santa María Vacation Deals

Cinco Quintas Hotel Boutique
Reviewed on May 31, 2026

ACASI Rustic Beach
Reviewed on Mar 16, 2026

Hotel Boutique Casa del Coliseo
Reviewed on Apr 26, 2026

Bora Bora Cartagena
Reviewed on May 1, 2026

Hotel Quadrifolio
Reviewed on Jan 22, 2026
Santa María Hotel Deals

GHL Corales de Indias
"Servicio 10/10"
Reviewed on May 30, 2026

OZ Hotel Collection
"Clean room"
Reviewed on Jun 10, 2026

Hotel Casa San Agustin
"Beautiful property. Exquisite service. Kind and available staff. Delicious breakfast."
Reviewed on Jun 4, 2026
Discover the most popular places to visit in Santa María

Bocagrande Beach
If a restful vacation is part of your travel plans, Bocagrande Beach might be the perfect place to seek out during your trip to Cartagena. Make time to visit the area's shops, or simply enjoy its top-notch restaurants.

Clock Tower
You can learn about the history of Cartagena when you stop by Clock Tower. Amble around the area's beautiful beaches or seek out the local tours.
Castillo Grande Beach
If a restful vacation is part of your travel plans, Castillo Grande Beach might be the perfect place to seek out during your trip to Cartagena.
What to do in Santa María

Full-Day Volcano of Totumo With Lunch, 5 pools and prívate Bach

Cartagena Island Hopping: 5-Stop Rosario Islands Tour with Lunch








