
Santa María Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $1,096 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Santa María Vacation
When you book a Santa María vacation package, you can kick back and enjoy your escape to the fullest. Uncover the highlights of this fascinating city knowing that all the travel planning has been looked after before you go. San Jose Beach and Plaza de Armas are a couple of the must-see sights to visit during a trip to Santa María. No matter your travel plans or the size of your budget, putting together a tailored Santa María vacation is a breeze with Expedia.
Santa María Hotel Deals

Carnaval Hotel Casino
Av. Irrazabal, 750 Encarnacion
Fully refundableReserve now, pay when you stay
The price is CA $83 per night from Apr 21 to Apr 22
CA $83
CA $92 total
Apr 21 - Apr 22
includes taxes & fees

Sun Hotel
Encarnacion Itapúa
The price is CA $104 per night from Apr 20 to Apr 21
CA $104
CA $115 total
Apr 20 - Apr 21
includes taxes & fees
9/10 Wonderful! (118 reviews)
Lastimosamente la experiencia que tuvimos en este hotel no fue tan buena. No funcionaba el aire acondicionado, no funcionaba la heladerita que tenia adentro, no tenian toallas en el cuarto. Y estuvimos esperando horas para que vengan a solucionar y el aire acondicionado funciono mas lento dormimos ...
Reviewed on Apr 9, 2026

Awa Resort Hotel
Ruta 1 Km 367, Calles Tajy y Naranjal Encarnacion
Fully refundable
The price is CA $94 per night from Apr 25 to Apr 26
CA $94
CA $105 total
Apr 25 - Apr 26
includes taxes & fees
9/10 Wonderful! (130 reviews)
Breakfasts was excellent very fresh and delicious and the area so clean
Reviewed on Mar 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in Santa María

The Best of Iguassu Falls, Itaipu Dam & City Tour
CA $276
per adult
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.







