Santa María Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Santa María Vacation
When you book a Santa María vacation package, you can kick back and enjoy your escape to the fullest. Uncover the highlights of this fascinating city knowing that all the travel planning has been looked after before you go. San Jose Beach and Plaza de Armas are a couple of the must-see sights to visit during a trip to Santa María. No matter your travel plans or the size of your budget, putting together a tailored Santa María vacation is a breeze with Expedia.
Ready to book your vacation to Santa María?
Santa María Hotel Deals
Sun Hotel
Encarnacion Itapúa
CA $81
CA $89 total
Sep 6 - Sep 7
includes taxes & fees
8.8/10 Excellent! (142 reviews)
"Excelente hotel y atención de todo el personal"
Reviewed on Aug 28, 2026
Carnaval Hotel Casino
Av. Irrazabal, 750 Encarnacion
Fully refundableReserve now, pay when you stay
CA $93
CA $102 total
Sep 13 - Sep 14
includes taxes & fees
Awa Resort Hotel
Ruta 1 Km 367, Calles Tajy y Naranjal Encarnacion
Fully refundableReserve now, pay when you stay
CA $103
CA $113 total
Sep 7 - Sep 8
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Santa María vacation package cost?
You can pick up a vacation package to this top destination on Expedia. But how much your vacation to Santa María costs will depend on factors like the length of stay, hotel choice and season.
What are the cheapest months to go to Santa María?
You're likely to find reduced prices and greater availability in January, February and April. Browse our cheap Santa María vacation packages and you could get some great off-season deals.
How many days is enough for Santa María?
Usually, a handful of days is enough to tick off the major sights during your Santa María vacation. However, if you prefer to have more time to kick back or go on day tours, think about extending your trip.
How to find the best Santa María package deals?
Use Expedia's filter tool to help you find some great Santa María package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your escape for midweek, or search for Santa María package deals in the low season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to book your vacation package as early as possible.
Is it cheaper to book a Santa María vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging flights and accommodations individually. Better still, you can customize your Santa María trip to match your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Santa María?
If you're considering a spur-of-the-moment Santa María trip, check out our last-minute deals that can be booked up to a week before you take off. Prefer not to wait until the last minute? You can find terrific deals on your flights and hotels by booking ahead.
How to plan a trip to Santa María?
- Choose your dates: The things you'd like to do in Santa Marían and your favourite season will help you decide when to get away.
- Budget wisely: In addition to the price of your hotel, you'll need to consider other expenses. These include food, transportation and flights. Also, put aside some extra funds for unexpected expenses that may come up during your trip to Santa María.
- Work out your trip length: Think about how much time you want to spend exploring Santa María. Plan your itinerary so you can get to all the experiences and attractions you're interested in at a leisurely pace.
- Bundle your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to choose a Santa María vacation package that brings all your bookings together.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
