Title: Book the Best BUSINESS Hotels in Santa Maria Island in 2025 | Expedia.ca [Santa Maria Island Travel Guide](https://expedia.ca/Santa-Maria-Island.dx3214)[Hotels in Santa Maria Island](https://expedia.ca/Santa-Maria-Island-Hotels.d3214.Travel-Guide-Hotels)[Vacation Rentals in Santa Maria Island](https://expedia.ca/Santa-Maria-Island-Vacation-Rentals.d3214.Travel-Guide-VacationRentals)[Flights to Santa Maria Island](https://expedia.ca/Cheap-Flights-To-Santa-Maria-Island.d3214.Travel-Guide-Flights)[Things to do in Santa Maria Island](https://expedia.ca/Things-To-Do-In-Santa-Maria-Island.d3214.Travel-Guide-Activities)[Santa Maria Island Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Maria-Island.d3214.Car-Rental-Guide)[Santa Maria Island Vacation Packages](https://expedia.ca/Santa-Maria-Island.d3214.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Santa Maria Island from CA $62 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Maria Island Business Hotels Tonight [Sep 16 - Sep 17](https://www.expedia.ca/Hotel-Search?regionId=3214&startDate=2025-09-16&endDate=2025-09-17&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 17 - Sep 18](https://www.expedia.ca/Hotel-Search?regionId=3214&startDate=2025-09-17&endDate=2025-09-18&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 19 - Sep 21](https://www.expedia.ca/Hotel-Search?regionId=3214&startDate=2025-09-19&endDate=2025-09-21&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=3214&startDate=2025-09-26&endDate=2025-09-28&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Santa Maria Island Business Hotels ## Our top choices for Santa Maria Island business-friendly hotels ![View from property](https://images.trvl-media.com/lodging/3000000/2490000/2483700/2483696/3208f491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2490000/2483700/2483696/266e83ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2490000/2483700/2483696/6f73b7b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Triple Room](https://images.trvl-media.com/lodging/3000000/2490000/2483700/2483696/7b8ae4c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Colombo Vila do Porto 7.6/10 Good (128) "Love coming back to this hotel!!" CA $117 CA $122 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Vila-Do-Porto-Hotels-Hotel-Colombo.h2483696.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/11000000/11000000/10994100/10994087/f48826b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/11000000/11000000/10994100/10994087/9c73ac94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/11000000/11000000/10994100/10994087/e60ed895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/11000000/11000000/10994100/10994087/9e8f1e0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Azores Youth Hostels - Santa Maria Vila do Porto 8.0/10 Very good (43) "Wonderfully clean hostel. " CA $62 CA $65 total includes taxes & fees Sep 23 - Sep 24 [](https://www.expedia.ca/Vila-Do-Porto-Hotels-PJA-Santa-Maria-Youth-Hostel.h10994087.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-09-30&endDate=2025-10-01®ionId=3214&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Maria Island Hotel Reviews ![Hotel Colombo](//images.trvl-media.com/lodging/3000000/2490000/2483700/2483696/3208f491_y.jpg) ### Hotel Colombo 10/10 Excellent "Love coming back to this hotel!!" [](https://expedia.ca/Vila-Do-Porto-Hotels-Hotel-Colombo.h2483696.Hotel-Information) ![Azores Youth Hostels - Santa Maria ](//images.trvl-media.com/lodging/11000000/11000000/10994100/10994087/f48826b1_y.jpg) ### Azores Youth Hostels - Santa Maria 10/10 Excellent "More of a hotel than a hotel. Plenty of room and comfortable accommodations " [](https://expedia.ca/Vila-Do-Porto-Hotels-PJA-Santa-Maria-Youth-Hostel.h10994087.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### More Hotel Options in Santa Maria Island - [Beach Hotel in Santa Maria Island](https://expedia.ca/Santa-Maria-Island-Hotels-Beach-Hotel.0-0-d3214-tBeachHotel.Travel-Guide-Filter-Hotels) - [Family Hotels in Santa Maria Island](https://expedia.ca/Santa-Maria-Island-Hotels-Family-Hotel.0-0-d3214-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Santa Maria Island](https://expedia.ca/Santa-Maria-Island-Hotels-Historic-Hotel.0-0-d3214-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Honeymoon Resorts and Hotels in Santa Maria Island](https://expedia.ca/Santa-Maria-Island-Hotels-Honeymoon-Hotels.0-0-d3214-tHoneymoonHotels.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues in Santa Maria Island](https://expedia.ca/Santa-Maria-Island-Hotels-Wedding-Hotels.0-0-d3214-tWeddingHotels.Travel-Guide-Filter-Hotels) - 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