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Santa Fe Island Vacation Rentals

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Check prices for these dates

In two weeks
Nov 20 - Nov 22
In two months
Jan 1 - Jan 3
In three months
Jan 29 - Jan 31
In four months
Feb 26 - Feb 28

Our top choices for Santa Fe Island vacation rentals

An outdoor patio with a wooden table and benches, surrounded by plants and a wooden fence.

1. Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (28 reviews)
"The host was so nice, kind, and friendly."
United States
Maho
The price is CA $185
CA $185 total
Nov 9 - Nov 10
Torre Mar Galapagos Boutique Suites
A patio with a round table and chairs, a blue umbrella, and a potted plant.

2. Suites

Suites
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (25 reviews)
"Check was early and friendly staff Room was super clean and comfortable"
United States
Judy
The price is CA $106
CA $118 total
Nov 9 - Nov 10
Suites
A covered outdoor area with a hammock, wooden benches, and a stone pathway.

3. Villa Mi Caleta Inn

Villa Mi Caleta Inn
2.0 star property
Puerto Ayora
The price is CA $283
CA $283 total
Nov 9 - Nov 10
Villa Mi Caleta Inn
A bedroom with a bed, a chair, and a view of the sea through large windows.

4. Suite with a spectacular ocean view—wake up to the sound of the ocean.

Suite with a spectacular ocean view—wake up to the sound of the ocean.
Puerto Ayora
8.0 out of 10, Very good, (1 review)
The price is CA $127
CA $206 total
Nov 14 - Nov 15
Suite with a spectacular ocean view—wake up to the sound of the ocean.
A couple sitting on a wicker sofa outdoors, with a table between them holding breakfast items and a book titled "GALAPAGOS".

5. Modern apartment with 18 feet ceilings and private terrace with view to a park

Modern apartment with 18 feet ceilings and private terrace with view to a park
Puerto Ayora
10.0 out of 10, Exceptional, (24 reviews)
"I highly recommend you stay here. Its is beautiful and also away from the crowd noise."
United States
Richard
The price is CA $159
CA $204 total
Nov 11 - Nov 12
Modern apartment with 18 feet ceilings and private terrace with view to a park
A modern kitchen with a central island, built-in appliances, and a dining area with wicker chairs.

6. VILLA MICONIA

VILLA MICONIA
3.0 star property
San Cristobal
The price is CA $226
CA $226 total
Nov 9 - Nov 10
VILLA MICONIA
A modern living room with a large table, a sofa, and a TV mounted on the wall.

7. Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"The place is perfect in every way, clean , spacious, great kitchen, comfortable beds, also the laundry facility is so helpful for longer stay. The host communication is excellent, immediate responds, great recommendations for the activities and local eats, location is also good , 10-15 minutes to walk to town center. we enjoyed our stay very much. highly recommend this place."
United States
Lihua
The price is CA $216
CA $294 total
Nov 9 - Nov 10
Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
A building with a white exterior, wooden vertical elements, and a cactus plant in the foreground.

8. Villa Galapagos

Villa Galapagos
2.5 star property
Puerto Ayora
6.0 out of 10, (1 review)
"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"
Japan
アオアシカツオドリ
The price is CA $127
CA $148 total
Nov 9 - Nov 10
Villa Galapagos
A modern kitchen with a dining table, chairs, pendant lights, a refrigerator, and a large window with curtains.

9. Colmena Apartment in the center of Puerto Ayora, Santa Cruz

Colmena Apartment in the center of Puerto Ayora, Santa Cruz
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We had an excellent experience at Five minutes from the malecon Santa Cruz - Puerto Ayora. The property is brand new, very secure, and perfectly located. What truly made our stay special was our host, Gaby. She was always available, attentive, and ready to help us with anything we needed. Had we known about this place earlier, we would have booked it for our entire stay in Santa Cruz. We highly recommend this accommodation to anyone visiting the island — it’s a gem!"
United States
jacques
The price is CA $165
CA $240 total
Nov 9 - Nov 10
Colmena Apartment in the center of Puerto Ayora, Santa Cruz
A checkered deck with outdoor seating, overlooking a marina with boats and a coastal town.

10. Galapagos Family Vacation 3 BR. Centrally located and Ocean View

Galapagos Family Vacation 3 BR. Centrally located and Ocean View
Puerto Ayora
10.0 out of 10, Exceptional, (29 reviews)
"Great communication with host, gave us information ahead of time for laundry services and taxi. Clean and wonderful property close to everything and great views."
United States
Amanda
The price is CA $362
CA $631 total
Nov 9 - Nov 10
Galapagos Family Vacation 3 BR. Centrally located and Ocean View
A hotel room with two beds, each with a blue and white bedspread, and a mural of a dolphin and islands on the wall.

11. Comfortable and Cozy Galarous Island Suite

Comfortable and Cozy Galarous Island Suite
Puerto Ayora
The price is CA $121
CA $138 total
Nov 9 - Nov 10
Comfortable and Cozy Galarous Island Suite
A multi-story building with a curved facade, balconies with glass railings, and a staircase leading to the upper floors.

12. TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."
Canada
Dean P.
The price is CA $97
CA $129 total
Nov 9 - Nov 10
TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
A rooftop terrace with a wooden bench, a potted plant, and a view of the cityscape and mountains.

13. 2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Puerto Ayora
The price is CA $96
CA $113 total
Nov 11 - Nov 12
2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
A glass-top table with a chair on a balcony with blue walls and potted plants.

14. Apartments on Galarous Island

Apartments on Galarous Island
Puerto Ayora
The price is CA $138
CA $155 total
Nov 9 - Nov 10
Apartments on Galarous Island
An outdoor patio with a wooden table and benches, surrounded by plants and a wooden fence.

15. Island Life Two-Bedroom Galapagos Casita

Island Life Two-Bedroom Galapagos Casita
Puerto Ayora
10.0 out of 10, Exceptional, (4 reviews)
"The host John was absolutely the BEST. He went above and beyond to make our stay wonderful. The house had everything one would need. "
United States
Trevor K.
The price is CA $249
CA $268 total
Nov 9 - Nov 10
Island Life Two-Bedroom Galapagos Casita
A wall with various woven wall hangings and a mirror.

16. Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
Puerto Ayora
The price is CA $116
CA $133 total
Nov 14 - Nov 15
Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
A hotel room with a bed, a sofa, a dresser, a mirror, and a view of an outdoor patio with a table and chairs.

17. Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Stay was great and I really enjoy Daniel’s helpful service— can’t wait to come back and stay again!"
United States
Will L.
The price is CA $141
CA $179 total
Nov 9 - Nov 10
Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
A bedroom with a bed, a wooden wardrobe, a blue laundry basket, and a window with curtains.

18. TWO Bedrooms Apartment ON THE First Floor Forest View

TWO Bedrooms Apartment ON THE First Floor Forest View
Puerto Ayora
The price is CA $97
CA $129 total
Nov 9 - Nov 10
TWO Bedrooms Apartment ON THE First Floor Forest View
A hotel room with two beds, a wooden door, a wall mural, and a small table with a lamp.

19. Galarous provides you with quality service and a warm welcome in your home

Galarous provides you with quality service and a warm welcome in your home
Puerto Ayora
The price is CA $106
CA $123 total
Nov 9 - Nov 10
Galarous provides you with quality service and a warm welcome in your home
A hotel room with a bed, a blue wall with island artwork, a green door, and a white ceiling.

20. A comfortable and welcoming continuation of Galarous Island

A comfortable and welcoming continuation of Galarous Island
Puerto Ayora
2.0 out of 10, (1 review)
"I stayed in 3 separate rooms, trying to find something acceptable. The rooms smelled musty and were covered in mold. The air conditioning was moldy and spread mold everywhere when turned on. In one room it looked like the ceiling was going to fall in on itself. There were huge cockroaches, live wires in the shower, branches protruding through the windows etc. over the course of my stay I broke out in a rash and started having respiratory issues. The front desk offered to change my room, then...
Canada
Flavia
The price is CA $51
CA $68 total
Nov 9 - Nov 10
A comfortable and welcoming continuation of Galarous Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Fe Island Hotel Reviews

A balcony with two white plastic chairs and a view of a coastal area with boats and buildings.
Posada del Mar

Posada del Mar

Posada del Mar
Puerto Ayora

10/10 Excellent

Great location & our room (suite 3) had a wonderful sea/port view.
Canada
Terry
Reviewed June 21, 2026
Posada del Mar

Find out more about Santa Fe Island

Everything you need to know about Santa Fe Island vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Fe Island vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Fe Island vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Fe Island vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Fe Island. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Fe Island vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Fe Island vacation rentals we have selected for you start as low as CA $51 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Santa Fe Island rentals

At Expedia, we put the best Santa Fe Island vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Fe Island rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Fe Island vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Fe Island. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.