Sanctuary Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Holiday Package Deals in Sanctuary

Price found within the past 48 hours. Click for updated prices.
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

Save 100% on your flight
CA $771
per person
Dec 11 - Dec 17
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Fort Myers (RSW)
8.6/10 Excellent! (1,787 reviews)
Would definitely stay here again!

Reviewed on Sep 20, 2026

Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina

Save 100% on your flight
CA $948
per person
Dec 11 - Dec 17
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Fort Myers (RSW)
9.4/10 Exceptional! (1,006 reviews)
Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa

Save 100% on your flight
CA $1,339
per person
Oct 29 - Nov 4
found 12 hours ago
Roundtrip flight included
Detroit (DTW) to Fort Myers (RSW)
8.6/10 Excellent! (1,005 reviews)
My husband and I were able to check in right on time. We were given a helpful overview of the property, a map, and list of the numerous amenities (complimentary kayaks, bikes, beach towels, pools and hot tubs, as well as the many restaurants, shops, rentals, and beach services) and opening and closing times said amenities. Prices for amenities and rentals were reasonable in my opinion. The restaurants range in price from reasonable to upscale dining. Our room was exactly as pictured. The entire property including the private beach - which was just across the road - were exceptionally clean. My only complaint was our bed was very firm for our tastes. The Gulf side beach was gorgeous. We saw many shore birds and dolphins. The bay side features a large marina and manatees in the cove. All staff we encountered were very friendly and helpful. We stayed in mid September and it appeared that most of the rooms were filled, but it was still very relaxing, quiet, and uncrowded. The location is excellent. It's easy to find off the main road through the islands and it's only a short drive to the attractions and beaches in both Sanibel and Captiva. Overall I would recommend and would stay here again.

Reviewed on Sep 20, 2026

Landing Apartments Fort Myers near Eastwood Village

Landing Apartments Fort Myers near Eastwood Village

Save 100% on your flight
CA $957
per person
Dec 11 - Dec 17
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Fort Myers (RSW)
9.6/10 Exceptional! (30 reviews)
This place is as beautiful as the pictures. Welcome kit has essentials for a short stay. The place is clean and cozy. Highly recommended.

Reviewed on Sep 4, 2026

Landing Fort Myers Near Highland Pines

Landing Fort Myers Near Highland Pines

Daniels Corridor
Save 100% on your flight
CA $824
per person
Dec 11 - Dec 17
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Fort Myers (RSW)
9.2/10 Wonderful! (14 reviews)
Very Clean

Reviewed on Sep 9, 2026

Where to stay in Sanctuary

Find the best Sanctuary areas and neighborhoods for the activities you enjoy most. Learn more about Sanctuary
A coastal scene with a lighthouse, beach, and ocean.

Mid Island

2 out of top 10 points of interest in this area

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

A coastal scene with a lighthouse, beach, and ocean.

West End

3 out of top 10 points of interest in this area

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

A coastal scene with a lighthouse, beach, and ocean.

East End

4 out of top 10 points of interest in this area

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

A cyclist on a paved path alongside a road with cars, palm trees, and a liquor store sign.

Beachview Country Club Estates

If you're spending some time in Beachview Country Club Estates, Sanibel Island Golf Club and Periwinkle Way are top sights worth seeing.

A beach with a green umbrella and two lounge chairs.

Gulf Shores

While there might not be top attractions in Gulf Shores, you can explore the larger area and discover places like Bowman's Beach and J. N. Ding Darling National Wildlife Refuge.

Sanctuary Hotel Deals

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

251 Crescent Street Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
CA $210
CA $305 total
Sep 29 - Sep 30
includes taxes & fees
9/10 Wonderful! (2,578 reviews)
"El parqueo debe estar incluido"

Reviewed on Sep 21, 2026

Margaritaville Beach Resort Fort Myers
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
CA $148
CA $197 total
Sep 27 - Sep 28
includes taxes & fees
8.8/10 Excellent! (2,040 reviews)
"Excellent hotel and location, clean, friendly staff, good vibes, delicious and affordable food. We’ll back."

Reviewed on Sep 22, 2026

Lani Kai Beachfront Resort
Sanibel Island Beach Resort

Sanibel Island Beach Resort

1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
CA $250
CA $318 total
Oct 4 - Oct 5
includes taxes & fees
9.2/10 Wonderful! (2,313 reviews)
"I recently enjoyed an unforgettable stay in Sanibel Island, and it was everything I could have hoped for in a beach getaway. From the moment I arrived, the warm, laid-back atmosphere and friendly staff made me feel instantly at home. The highlight was definitely the direct beach access — just a few ..."

Reviewed on Sep 22, 2026

Sanibel Island Beach Resort
See all 13,181 properties in Sanctuary
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sanctuary vacation package cost?
Starting from as little as CA $771, you can tailor your Sanctuary package the way you want. Simply combine hotels, flights and car rentals and we'll reward you with discounts.
How do I get a cheap travel package to Sanctuary?
Booking a flight and hotel together with Expedia won't just save you time — it'll save you a pretty penny too. A Sanctuary vacation package makes it easy to organize your dream adventure. With more than 550 airlines across the world to choose from, finding convenient flights that suit your schedule won't be hard. On top of that, we've got over 1,000,000 properties globally to select from. Now that's what we call choice. No matter who you are, Expedia brings the world within your reach.
Where should I stay in Sanctuary?
A getaway to Sanctuary wouldn't be complete without seeing Bowmans Beach, Blind Pass Beach and Castaways Marina. Spend your evenings close to these top attractions and make sightseeing a breeze.
How far in advance should I book my Sanctuary vacation?
Reward yourself with the biggest variety at the lowest prices by booking your vacation to Sanctuary early. Airlines typically release flight tickets around 12 months prior to departure, so start your planning ASAP. That said, Expedia is committed to providing you with the best deals around, so it's never a bad time to book your dream vacation!
What does an Expedia Sanctuary travel package include?
That depends on what you're after. If you're traveling by yourself, you might decide to bundle flights and hotels. Taking the whole family to Sanctuary? A travel package that includes hotels, rental cars and flights might suit you better. Expedia gives you the freedom and flexibility to tailor-make your travel package.
What should I know before booking a Sanctuary travel package?
Booking all the parts of your escape together is a terrific way to save. Bundle your car rentals, airfares and hotels into one package. But you're not limited to hotels. Expedia offers all types of properties, including vacation rentals like beachfront villas and spacious residences. The list goes on!
Can I choose my airline with a Sanctuary Expedia vacation package?
Most definitely. Expedia has over 550 partner airlines to choose from globally. With so much choice, finding the perfect carrier to whisk you away to Sanctuary won't be difficult.
If I'm not able to travel, can I cancel my Sanctuary vacation package?
Don't stress if you're rethinking your Sanctuary vacation package — it's possible to change or amend your booking. And if you've booked it within the last 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We totally understand life can sometimes throw you a curveball, so make your way to our Customer Service Portal if that happens. When you're ready to make changes, we'll be here to help.

Things to do

Fort Myers Beach Dolphin & Sightseeing Tour Refreshments Included

Fort Myers Beach Dolphin & Sightseeing Tour Refreshments Included

CA $90
per adult
Fort Myers Beach Dolphin & Sightseeing Tour Refreshments Included
Guided Kayak Eco Tour - Bunche Beach

Guided Kayak Eco Tour - Bunche Beach

CA $97
per adult
98% of travellers recommend
Guided Kayak Eco Tour - Bunche Beach
See all activities in Sanibel
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.