Sanctuary Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Top Holiday Package Deals in Sanctuary

Price found within the past 48 hours. Click for updated prices.
Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral

2 out of 5
Price was CA $756, price is now CA $503 per person
CA $503
per person
Aug 22 - Aug 29
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Fort Myers (RSW)
7.4/10 Good! (330 reviews)
It was a great experience

Reviewed on Jun 17, 2026

GullWing Beach Resort

GullWing Beach Resort

3.5 out of 5
South Island
Price was CA $1,735, price is now CA $1,122 per person
CA $1,122
per person
Aug 22 - Aug 29
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Fort Myers (RSW)
9.4/10 Exceptional! (951 reviews)
Updated bathrooms and kitchen

Reviewed on May 31, 2026

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa

3 out of 5
Price was CA $2,172, price is now CA $1,422 per person
CA $1,422
per person
Aug 22 - Aug 29
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Fort Myers (RSW)
8.6/10 Excellent! (1,008 reviews)
Pool was our kids (2&5) favorite part. We never had to leave the property. Wish there was a breakfast package/buffet available. Beach was awesome.. shelling… amazing. Would 100% recommend charter with Captain Randy, he asks what you want/ expect for the day and makes it reality. We had dolphins chasing us to a private island to shell, everyone loved it! We have planned our trip for next year with family.

Reviewed on Jun 16, 2026

LaPlaya Beach & Golf Resort - A Noble House Resort

LaPlaya Beach & Golf Resort - A Noble House Resort

4.5 out of 5
Vanderbilt Beach
Price was CA $2,798, price is now CA $1,842 per person
CA $1,842
per person
Jul 30 - Aug 3
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Fort Myers (RSW)
9/10 Wonderful! (1,018 reviews)
Excellent. I will definitely come back

Reviewed on Jun 15, 2026

Casa Ybel Resort

Casa Ybel Resort

2.5 out of 5
Mid Island
Price was CA $2,432, price is now CA $1,604 per person
CA $1,604
per person
Aug 22 - Aug 29
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Fort Myers (RSW)
8.8/10 Excellent! (359 reviews)
Beach view was great it was nice having a kitchen

Reviewed on Jun 19, 2026

Where to stay in Sanctuary

Find the best Sanctuary areas and neighborhoods for the activities you enjoy most. Learn more about Sanctuary
A coastal scene with a lighthouse, beach, and ocean.

Mid Island

3 out of top 10 points of interest in this area

While visiting Mid Island, you might make a stop by sights like Sanibel Island Southern Beach and Periwinkle Way.

Find hotels in Mid Island

Sanctuary Hotel Deals

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is CA $287 per night from Jul 2 to Jul 3
CA $287
CA $370 total
Jul 2 - Jul 3
includes taxes & fees
8.6/10 Excellent! (1,002 reviews)
"Beautiful after a major delay and missing our flight the hotel was wonderful and generous since the travel insurance purchased from Expedia did not help one bit I’d highly recommend this resort it was beautiful amazing and so accommodating and luxurious"

Reviewed on Jun 18, 2026

Marriott Sanibel Harbour Resort & Spa
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is CA $274 per night from Jul 6 to Jul 7
CA $274
CA $376 total
Jul 6 - Jul 7
includes taxes & fees
9/10 Wonderful! (2,227 reviews)
"Front desk staff was a great help. Check in/out was swift. Drinks were great and atmosphere was nice."

Reviewed on Jun 18, 2026

Margaritaville Beach Resort Fort Myers
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is CA $167 per night from Jun 23 to Jun 24
CA $167
CA $218 total
Jun 23 - Jun 24
includes taxes & fees
9/10 Wonderful! (1,628 reviews)
"I love this resort and this was our second trip as a group. Understanding they are still getting back to where they were before with staff was expected, but a few things were miscommunicated or not communicated. We were not told the island view was closing or we would have made it up on our trip ..."

Reviewed on Jun 19, 2026

Lani Kai Beachfront Resort
See all 13,094 properties in Sanctuary
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a Sanctuary vacation package cost?
Starting from as little as CA $503, you can tailor your Sanctuary package the way you want. Simply combine hotels, flights and car rentals and we'll reward you with discounts.
How do I get a cheap travel package to Sanctuary?
Booking a flight and hotel together with Expedia won't just save you time — it'll save you a pretty penny too. A Sanctuary vacation package makes it easy to organize your dream adventure. With more than 550 airlines across the world to choose from, finding convenient flights that suit your schedule won't be hard. On top of that, we've got over 1,000,000 properties globally to select from. Now that's what we call choice. No matter who you are, Expedia brings the world within your reach.
Where should I stay in Sanctuary?
A getaway to Sanctuary wouldn't be complete without seeing Bowmans Beach, Blind Pass Beach and Castaways Marina. Spend your evenings close to these top attractions and make sightseeing a breeze.
How far in advance should I book my Sanctuary vacation?
Reward yourself with the biggest variety at the lowest prices by booking your vacation to Sanctuary early. Airlines typically release flight tickets around 12 months prior to departure, so start your planning ASAP. That said, Expedia is committed to providing you with the best deals around, so it's never a bad time to book your dream vacation!
What does an Expedia Sanctuary travel package include?
That depends on what you're after. If you're traveling by yourself, you might decide to bundle flights and hotels. Taking the whole family to Sanctuary? A travel package that includes hotels, rental cars and flights might suit you better. Expedia gives you the freedom and flexibility to tailor-make your travel package.
What should I know before booking a Sanctuary travel package?
Booking all the parts of your escape together is a terrific way to save. Bundle your car rentals, airfares and hotels into one package. But you're not limited to hotels. Expedia offers all types of properties, including vacation rentals like beachfront villas and spacious residences. The list goes on!
Can I choose my airline with a Sanctuary Expedia vacation package?
Most definitely. Expedia has over 550 partner airlines to choose from globally. With so much choice, finding the perfect carrier to whisk you away to Sanctuary won't be difficult.
If I'm not able to travel, can I cancel my Sanctuary vacation package?
Don't stress if you're rethinking your Sanctuary vacation package — it's possible to change or amend your booking. And if you've booked it within the last 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We totally understand life can sometimes throw you a curveball, so make your way to our Customer Service Portal if that happens. When you're ready to make changes, we'll be here to help.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.