Title: Book the Best San Luis SPA Resorts - Spa Hotels in San Luis, CO | Expedia.ca [Hotels in San Luis](https://expedia.ca/San-Luis-Hotels.d3000429673.Travel-Guide-Hotels)[Vacation Rentals in San Luis](https://expedia.ca/San-Luis-Vacation-Rentals.d3000429673.Travel-Guide-VacationRentals)[San Luis Car Rentals](https://expedia.ca/Car-Rentals-In-San-Luis.d3000429673.Car-Rental-Guide)[San Luis Vacation Packages](https://expedia.ca/San-Luis.d3000429673.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/63ca537bdd3832d6ae2453b24ced012c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Jeff White # Find Spa Hotels in San Luis, CO ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on San Luis Spa Hotels Tonight [Oct 2 - Oct 3](https://www.expedia.ca/Hotel-Search?regionId=3000429673&startDate=2025-10-02&endDate=2025-10-03&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 3 - Oct 4](https://www.expedia.ca/Hotel-Search?regionId=3000429673&startDate=2025-10-03&endDate=2025-10-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=3000429673&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=3000429673&startDate=2025-10-10&endDate=2025-10-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top San Luis Spa Hotels ## Top San Luis Hotel Reviews ## Frequently asked questions ### Looking to vacation at a spa hotel in San Luis? > Soothe the senses with some time in one of our wonderful spa hotels. Check out the mountain views in San Luis - worth a picture or two! Be sure to enjoy the many popular restaurants during your stay. Spa hotels are a great way to take a break from your daily routine and add a layer of luxury to your vacation. ### What's there to see and do in San Luis? > Take in the sights and attractions that San Luis offers with a visit to Rio Grande, Shrine of the Stations of the Cross, and Mother Mary's Garden. If you have a little extra time during your trip, you might want to check out Fort Garland Museum and Los Caminos Antiguos. ### What is a San Luis spa hotel? > Spa hotels in San Luis have full on-site spas and offer services like couples massages and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. 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