San Isidro Vacation Packages

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Your San Isidro Vacation

Say goodbye to the hassle of planning and hello to a San Isidro vacation package. With the finer details organized before you take off, you can focus on discovering every inch of this city, starting with Cartagena Walled City, which is great for views, dining and bars and pubs. If a sightseeing tour is part of the program during your trip to San Isidro, stop by leading attractions like San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Jaime Moron Stadium. Whoever you're heading away with and whatever you want to spend, your ultimate San Isidro vacation is just a few clicks away with Expedia.

Top Holiday Package Deals in San Isidro

Price found within the past 48 hours. Click for updated prices.
Casa Bali Castillo View Private Pool & R

Casa Bali Castillo View Private Pool & R

Pie del Cerro
Save 100% on your flight
CA $1,829
per person
Nov 21 - Nov 28
found 5 hours ago
Roundtrip flight included
Toronto (YYZ) to Cartagena (CTG)
10/10 Exceptional! (1 review)
Excelente ubicación, buenas instalaciones, en la recepción tanto Omar como la recepcionista fueron muy amables en todo momento.

Reviewed on Feb 17, 2026

Casa DiLuca Cartagena Hotel Boutique

Casa DiLuca Cartagena Hotel Boutique

Cartagena Walled City
Save 100% on your flight
CA $2,211
per person
Jan 4 - Jan 11
found 9 hours ago
Roundtrip non-stop flight included
Montreal (YUL) to Cartagena (CTG)
8.8/10 Excellent! (199 reviews)
Everything was always wonderful. I always stay here when I come to Cartagena

Reviewed on Oct 5, 2026

Hotel Quadrifolio

Hotel Quadrifolio

Cartagena Walled City
Save 100% on your flight
CA $2,190
per person
Nov 25 - Dec 2
found 1 day ago
Roundtrip flight included
Montreal (YMQ) to Cartagena (CTG)
10/10 Exceptional! (167 reviews)
Beautiful place, the highlight of our trip. Big and nice rooms with all the amenities. Nice breakfast and amazing service.

Reviewed on Oct 11, 2026

Casa del Arzobispado Hotel

Casa del Arzobispado Hotel

Cartagena Walled City
Save 100% on your flight
CA $3,708
per person
Jan 2 - Jan 9
found 6 hours ago
Roundtrip flight included
Montreal (YMQ) to Cartagena (CTG)
9.4/10 Exceptional! (355 reviews)
Cinco Quintas Hotel Boutique

Cinco Quintas Hotel Boutique

Cartagena Walled City
Save 100% on your flight
CA $1,983
per person
Nov 25 - Dec 2
found 1 day ago
Roundtrip flight included
Montreal (YMQ) to Cartagena (CTG)
9.6/10 Exceptional! (339 reviews)
Na

Reviewed on Oct 8, 2026

Where to stay in San Isidro

Find the best San Isidro areas and neighborhoods for the activities you enjoy most. Learn more about San Isidro
A coastal cityscape with a prominent skyscraper, a marina with boats, and historic buildings with red-tiled roofs.

Cartagena Walled City

3 out of top 10 points of interest in this area

Cartagena Walled City is known for its ample dining options, and you can make a stop by Clock Tower and Bolivar Square while in the area.

Find hotels in Cartagena Walled City
A coastal cityscape with high-rise buildings along a curved shoreline.

Bocagrande

1 out of top 10 points of interest in this area

Boasting the city's most prominent hotels, this upscale area offers shopping at Plaza Bocagrande and Nao Mall, and is close to the popular Ciudad Amurallada. Enjoy various dining options and easy access to the Transcaribe station.

Find hotels in Bocagrande
A coastal town with a prominent church featuring a tall bell tower and a domed roof.

Getsemani

Travelers come to Getsemani for its abundant dining options, and you can see top attractions like Plaza de la Trinidad and Los Pegasos Dock while you're in town.

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A coastal cityscape with historic buildings, a marina, and a prominent church tower.

Cartagena Centro

Unique features of Cartagena Centro include the museums and historic sites. Make a stop by Plaza Santo Domingo or Bolivar Square while you're exploring the area.

Find hotels in Cartagena Centro
A man playing a guitar on a colorful street with yellow, blue, and pink buildings.

San Diego

San Diego is known for its ample dining options, and you can make a stop by House of Gabriel Garcia Marquez and Las Bovedas while in the area.

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San Isidro Hotel Deals

OZ Hotel Collection

OZ Hotel Collection

6-164 Carrera 2 Cartagena
Fully refundableReserve now, pay when you stay
CA $154
CA $154 total
Oct 17 - Oct 18
9.6/10 Exceptional! (816 reviews)
"Awesome place"

Reviewed on Oct 12, 2026

OZ Hotel Collection
Sofitel Barú Cartagena

Sofitel Barú Cartagena

KM 7 Sector, Porto Nao Cartagena Bolívar
Fully refundableReserve now, pay when you stay
CA $475
CA $475 total
Nov 2 - Nov 3
9.4/10 Exceptional! (826 reviews)
"Muy buena opción para descansar en familia o pareja y tener playa bonita"

Reviewed on Oct 12, 2026

Sofitel Barú Cartagena
Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive

Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive

Anillo Vial, Km 12, between Manzanillo Cartagena Bolivar
Fully refundableReserve now, pay when you stay
CA $414
CA $414 total
Nov 12 - Nov 13
Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive
See all 4,092 properties in San Isidro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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All Inclusive Vacations
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Frequently asked questions

How much does a San Isidro vacation package cost?
Our San Isidro vacation packages, which begin at just CA $1,829, are the perfect way to save big. Select your favorite hotels, flights and more to create a personalized escape.
How do I get a cheap travel package to San Isidro?
Booking a flight and hotel together with Expedia won't just save precious time — it'll save you a pretty penny too. A San Isidro vacation package makes it a cinch to organize your ideal trip. With more than 550 airlines throughout the world to select from, finding flights that fit your busy schedule will be no sweat. Not only that, we've got over 1,000,000 hotels globally to pick from. Now that's what you call choice. No matter who you are, Expedia will help show you the world.
Where should I stay in San Isidro?
Most visitors who travel to San Isidro include San Felipe de Barajas Castle and San Pedro Claver Church and Convent on their bucket lists. Why not select a hotel right near these main attractions?
How far in advance should I book my San Isidro vacation?
Be rewarded with the widest variety at the lowest prices by booking your trip to San Isidro early. Air carriers typically release flight tickets anywhere up to 12 months in advance, so start locking things in as soon as you can. That being said, Expedia is constantly working to give you the best deals around, so it's always a good time to book your dream vacation!
What does an Expedia San Isidro travel package include?
It comes down to what sort of escape you have in the works. San Isidro vacation deals can include car rentals, flights and hotels. You can mix and match to find the bundle that suits your style and budget. You can also add on activities and experiences after you've booked to land even bigger discounts.
What should I know before booking a San Isidro travel package?
A travel package can be tailored to your budget and is a terrific way to make your hard-earned dollars stretch further. How much you include is up to you. Hotels, rental cars and flights — come up with a combination that suits your plans.
Can I choose my airline with a San Isidro Expedia vacation package?
With a vacation package, you're the boss. Whether you're hoping to fly to San Isidro in coach or first class, simply select from the available airline options. Expedia has access to more than 550 airline partners throughout the world.
If I'm not able to travel, can I cancel my San Isidro vacation package?
Whether it's your hotel or flight, yes, you can cancel or amend it. Locked in your San Isidro vacation package in the last 24 hours? You may be able to make changes or cancellations at no cost. For older bookings, you may be charged a fee by your airline, hotel or car rental company. For more details, take a look at our Customer Service Portal. We'll help you each step of the way.

Things to do

Cartagena Island Hopping: 5-Stop Rosario Islands Tour with Lunch

Cartagena 5 Island Hop Tour: Lunch, Snorkel, Beach Clubs, & More

CA $98
per adult
84% of travellers recommend
Cartagena 5 Island Hop Tour: Lunch, Snorkel, Beach Clubs, & More
Enjoy a beautiful sunset

Luxury Cartagena Sunset Pirate ship Adventure, Cannon Show&Drinks

CA $66
per adult
88% of travellers recommend
Luxury Cartagena Sunset Pirate ship Adventure, Cannon Show&Drinks
Cartagena: Rosario Islands and Playa Blanca Excursion with Snorkeling or Aquarium

Cartagena: Rosario Islands and Playa Blanca Excursion with Snorkeling or Aquarium

CA $110
per adult
100% of travellers recommend
Cartagena: Rosario Islands and Playa Blanca Excursion with Snorkeling or Aquarium
See all activities in Cartagena
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.