Roxana Vacation Packages

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Your Roxana Vacation

Let our vacation packages to Roxana inspire your next escape. There's tons to love about this exciting city, starting with the neighborhood of Old Jamestown, which is great for nature and walking. Fill your free time with tours of Fast Eddies Bon Air, Robert Wadlow Statue and Lewis and Clark Interpretive Center, some of the top attractions you should see during your trip to Roxana. Your dream Roxana vacation is a few clicks away. Search hotels, airfares and more on Expedia for a getaway that's tailored to suit your travel style.

Top Roxana Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Moonrise Hotel

Moonrise Hotel

4 out of 5
Delmar Loop
Price was CA $915, price is now CA $782 per person
CA $782
per person
Sep 11 - Sep 13
found 9 hours ago
Roundtrip flight included
Detroit (DTW) to St. Louis (STL)
9/10 Wonderful! (1,976 reviews)
We had to leave for a different in the middle of the night as it was so loud at this hotel. Do not stay here. The staff was very rude and unhelpful about the noise. I have never had such a bad experience at a hotel - we were left in a lurch due to the rude staff who had no regard for guests but instead were hanging out with friends in the lobby who were also going up to the rooftop bar that was so loud we could not hear ourselves in our room. Nightmare experience.

Reviewed on Jul 5, 2026

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was CA $1,086, price is now CA $792 per person
CA $792
per person
Sep 11 - Sep 13
found 9 hours ago
Roundtrip flight included
Detroit (DTW) to St. Louis (STL)
9.2/10 Wonderful! (1,661 reviews)
Enjoyed our stay everything was adequate nothing over the top just nice with comfortable beds

Reviewed on Jul 3, 2026

Landing Amazing 1bd, Yoga Studio, Gym

Landing Amazing 1bd, Yoga Studio, Gym

3 out of 5
DeBaliviere Place
Price was CA $1,317, price is now CA $1,144 per person
CA $1,144
per person
Sep 11 - Sep 13
found 9 hours ago
Roundtrip flight included
Detroit (DTW) to St. Louis (STL)
No reviews

Garden House Bed and Breakfast

Garden House Bed and Breakfast

2 out of 5
Price was CA $1,452, price is now CA $1,277 per person
CA $1,277
per person
Sep 7 - Sep 14
found 1 day ago
Roundtrip flight included
Montreal (YUL) to St. Louis (STL)
8.4/10 Very good! (43 reviews)
Chris absolutely made our stay!!!! A great place, wonderful host, breakfast was great. If we go to Hannibal again, this is absolutely the place we will stay!!!!

Reviewed on Jun 22, 2026

Best Western On The River

Best Western On The River

2.5 out of 5
Price was CA $1,557, price is now CA $1,371 per person
CA $1,371
per person
Sep 7 - Sep 14
found 1 day ago
Roundtrip flight included
Montreal (YUL) to St. Louis (STL)
8.6/10 Excellent! (1,011 reviews)
The pool and hot tub was very clean and so was the room! But I didn’t appreciate the housekeeping staff telling me that I needed to get out and that check out was 11:00 and they had to get room ready for next guest! I had already discussed this with check in and I was sick on top of everything! Made me feel like I wasn’t an important paying guest!

Reviewed on Jul 6, 2026

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Roxana Hotel Deals

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $204 per night from Jul 31 to Aug 1
CA $204
CA $241 total
Jul 31 - Aug 1
includes taxes & fees
8.6/10 Excellent! (4,184 reviews)
"good"

Reviewed on Jul 6, 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $134 per night from Jul 12 to Jul 13
CA $134
CA $156 total
Jul 12 - Jul 13
includes taxes & fees
8.8/10 Excellent! (3,268 reviews)
"I absolutely loved my stay at Clayton Plaza Hotel! It was beautiful inside and out. All the staff were very friendly and hospitable plus the breakfast was delicious. Not often do you get a buffet style breakfast with your stay at hotels!! Whenever I come back to St Louis this will be where I’d stay ..."

Reviewed on Jul 6, 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
The price is CA $128 per night from Jul 20 to Jul 21
CA $128
CA $150 total
Jul 20 - Jul 21
includes taxes & fees
9.2/10 Wonderful! (3,067 reviews)
"Great place to stay."

Reviewed on Jul 6, 2026

Pear Tree Inn St. Louis Airport
See all 1,508 properties in Roxana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Roxana attractions

Wood River Refinery History Museum

You can spend an afternoon studying the exhibits at Wood River Refinery History Museum in Roxana.
See properties

Frequently asked questions

How much does a Roxana vacation package cost?
You'll find cheap prices from CA $782 on Expedia for your Roxana break. However, factors like the hotel choice, length of stay and season will determine how much your vacation to Roxana costs.
What are the cheapest months to go to Roxana?
January, February and November are great times to look for cheap Roxana vacation packages. Choosing to travel in less busy months means you'll typically find reduced prices on accommodations and flights.
How many days is enough for Roxana?
For your Roxana vacation, a few days will be enough to see all the highlights. Make sure to check out National Great Rivers Museum — it's one of the leading sights in this destination. If you're looking for more activities, think about basing yourself here and venturing off on some tours from Roxana.
How to find the best Roxana package deals?
Landing a cheap Roxana package deal is easy with Expedia. After you've entered your trip dates and destination under our "Packages" tab, set your budget, apply a few filters and browse what's available. You can fine-tune your search by "Amenities," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to view the most pocket-friendly Roxana package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider travelling on a weekday, when prices are typically lower.
Is it cheaper to book a Roxana vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to booking flights and stays separately. Better still, you can personalize your Roxana getaway to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Roxana?
If you have your Roxana vacation dates finalized, book as soon as you can to bag some terrific deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spontaneous trips? Our last-minute deals are perfect for travelling on a whim.
How to plan a trip to Roxana?

  1. Choose the best time to travel: Your schedule, favourite season and the type of weather you enjoy can all influence your decision on when to travel to Roxana.
  2. Calculate your budget: Make sure you have enough money to pay for everything from transportation and food to activities and airfares. Your accommodations will probably be the biggest expense during your trip to Roxana.
  3. Decide your trip length: Consider how much time you'd like to spend exploring Roxana. Plan your itinerary so you can get to all the activities and attractions you're interested in without rushing.
  4. Bundle your bookings: With your travel dates in order, you can combine your hotels, car rental, flights and more into a personalized Roxana vacation package.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.