Book The Best Hotels in Great River Road for 2026 from CA $117 - Fully Refundable Options

A historic downtown street with vintage buildings, a church steeple, and a prominent clock tower.

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Our top choices for Great River Road hotels

An indoor swimming pool with a blue interior, surrounded by a seating area with blue cushions and wicker furniture.

A hotel room with a large bed, two bedside tables with lamps, a TV, a shower area, and a bathroom.

A dining area with multiple tables and chairs, a kitchen area with appliances, and a blue wall.

A patio area with outdoor seating and a covered section, adjacent to a building with large windows.

1. AmericInn by Wyndham Prairie du Chien

Prairie Du Chien

Angie

CA $106

CA $117 total

includes taxes & fees

Oct 26 - Oct 27

A Fairfield by Marriott hotel with a modern design, featuring a covered entrance, multiple floors, and a landscaped area with trees and shrubs.

An indoor swimming pool with a stone wall, seating area, and large windows.

A hotel room with a large window, a TV, a desk, a chair, a sofa, and a lamp.

A modern living room with a stone accent wall, a sofa, a coffee table, and a chair.

2. Fairfield Inn & Suites by Marriott La Crosse Downtown

Historic Downtown La Crosse

michael

CA $143

CA $164 total

includes taxes & fees

Nov 8 - Nov 9

A compact hotel room with a kitchenette, a sofa, a coffee table, and a bed.

A reception area with a wooden counter, a red patterned armchair, and a potted plant with red flowers.

A garden with a central fountain, surrounded by a brick pathway and various plants.

A living room with two beige sofas, a fireplace, and a flat-screen TV mounted on a brick wall.

3. Days Inn by Wyndham Lake Village

Lake Village

Ronitta

CA $114

CA $128 total

includes taxes & fees

Nov 13 - Nov 14

A rooftop terrace with wicker furniture, offering a city view.

A lobby with seating areas, a chandelier, and a large pillar.

A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.

A modern hotel lobby with a bar area, seating arrangements, and a large chandelier.

4. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

Theresa

CA $190

CA $223 total

includes taxes & fees

Oct 25 - Oct 26

An indoor swimming pool with a hot tub, lounge chairs, and a brick wall with artwork.

A hotel room with two beds, a desk, a TV, and a painting on the wall.

5. Pear Tree Inn St. Louis Near Union Station

Downtown West

Larry

CA $147

CA $172 total

includes taxes & fees

Oct 25 - Oct 26

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

A park with a pathway, trees, and a modern sculpture.

A rooftop lounge with large windows, red seating, and a view of the cityscape.

A modern hotel room with a large window, a flat-screen TV mounted on the wall, a round dining table with chairs, and a patterned rug.

6. Hyatt Regency St. Louis at The Arch

Downtown St. Louis

David

CA $189

CA $223 total

includes taxes & fees

Oct 30 - Oct 31

An indoor pool area with a hot tub, seating, and a stone wall.

A hotel room with a large bed, two bedside tables with lamps, a patterned wall, and a framed picture on the wall.

A conference room with a large table, six chairs, a flat-screen TV, and a patterned carpet.

An indoor pool area with a hot tub, lounge chairs, and a towel service station.

7. Drury Plaza Hotel St. Louis Union Station

Downtown West

Andrea

CA $160

CA $190 total

includes taxes & fees

Nov 1 - Nov 2

The Clayton Plaza Hotel sign with a stone wall and plants in front.

A lobby with a chandelier, a round table with a floral arrangement, and a painting on the wall.

A large conference room with rows of tables and chairs, a podium, and a buffet table with plates and napkins.

A hotel lobby with a reception desk, a chandelier, and artwork on the wall.

8. Clayton Plaza Hotel & Extended Stay

Clayton

Sarah

CA $131

CA $153 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

9. Wingate by Wyndham St. Louis Airport

St. Ann

Rachal

CA $136

CA $161 total

includes taxes & fees

Oct 27 - Oct 28

A cozy lounge area with leather sofas, a fireplace, and a bar counter.

An outdoor patio area with a pool, red umbrellas, and seating arrangements.

A restaurant with a central bar area, seating arrangements, and a fireplace.

A modern building with a unique, curved roof structure.

10. The Cheshire

Richmond Heights

Matthew

CA $209

CA $249 total

includes taxes & fees

Oct 27 - Oct 28

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A modern lobby with blue seating, a reception desk, and large windows.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

11. Hyatt Select St. Louis Airport

Woodson Terrace

Daisy

CA $155

CA $192 total

includes taxes & fees

Oct 29 - Oct 30

A rooftop restaurant with round tables, chairs, and a view of the city.

A hotel with a prominent sign reading "MOONRISE."

A modern lobby with a staircase, seating area, and wall-mounted artwork.

A rooftop terrace with seating areas, a decorative moon sculpture, and string lights.

12. Moonrise Hotel

Delmar Loop

Jessie

CA $227

CA $270 total

includes taxes & fees

Oct 27 - Oct 28

A courtyard with outdoor seating, a central fountain, and a view of a tower.

The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

A hotel room with two beds, a desk, and a chair.

A buffet setup with various food items, a coffee station, and a refrigerator with beverages.

13. The Knight Center at Washington University

St. Louis

Rosalyn

CA $204

CA $235 total

includes taxes & fees

Nov 19 - Nov 20

An indoor swimming pool with a curved design, surrounded by palm trees and a white pool ladder.

A modern hotel lobby with a reception desk, a digital information kiosk, and a patterned floor.

A modern interior with a fireplace, a green armchair, and a patterned rug.

A hotel room with a large bed, a desk, a chair, and a view of the outdoors through the window.

14. Treasure Island Resort & Casino

Welch

Kristine

CA $118

CA $147 total

includes taxes & fees

Nov 19 - Nov 20

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A hotel room with a bed, a desk, a television, and a lamp.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

15. Pear Tree Inn St. Louis Airport

St. Ann

Brittany

CA $125

CA $148 total

includes taxes & fees

Nov 2 - Nov 3

A modern lobby with a reception desk, seating area, and a large wall with a unique design.

An indoor swimming pool with a high ceiling, clear signage, and a tiled floor.

A modern hotel lobby with a central wooden reception desk, a large light fixture, and a food display.

A hotel room with a sofa, a bed, a painting on the wall, and a window with curtains.

16. Hyatt Place Minneapolis Airport-South

East Bloomington

Kyle

CA $124

CA $144 total

includes taxes & fees

Nov 15 - Nov 16

An indoor swimming pool area with multiple lanes, lounge chairs, and a small seating area.

A modern hotel lobby with seating areas, including sofas and chairs, and a large window with blinds.

A lobby with patterned sofas, a fireplace, and framed pictures on the wall.

A lobby with two armchairs, a lamp, a framed artwork, and a sign indicating a fitness center.

17. Drury Inn & Suites St. Louis O'Fallon, IL

O'Fallon

Yoav

CA $143

CA $166 total

includes taxes & fees

Nov 15 - Nov 16

A modern bar area with a long counter, seating, and pendant lighting.

A reception area with a marble counter, a potted plant, and a decorative geometric planter.

A modern lounge area with leather armchairs, a round coffee table, and a large wooden pillar.

A modern hotel room with a sofa, armchair, desk, and large windows offering a city view.

18. Cambria Hotel Bloomington Mall of America Minneapolis Airport

East Bloomington

MITCH

CA $131

CA $152 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor dining area with tables and chairs, surrounded by a wooden deck and a railing.

A library with wooden bookshelves, a fireplace, and seating areas.

A library with bookshelves, a blue sofa, and a staircase.

A reception desk with a sign, a coffee machine, and a seating area with blue sofas.

19. Irish Cottage Inn & Suites

Galena

Mark

CA $112

CA $164 total

includes taxes & fees

Oct 21 - Oct 22

A vending machine with various beverages and snacks.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A breakfast buffet area with a bakery section, a coffee station, and a display case with pastries.

A hotel room with a bed, a blue sofa, a small table, and two wall-mounted lamps.

20. Holiday Inn Express & Suites Mall of America - MSP Airport by IHG

East Bloomington

Mary

CA $140

CA $162 total

includes taxes & fees

Nov 17 - Nov 18

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Discover things to see and do in Great River Road as you venture to popular sights like Canal Street.

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A small island surrounded by a calm lake with dense green foliage and a clear blue sky.

Top Great River Road Hotel Reviews

AmericInn by Wyndham Prairie du Chien

10/10 Excellent

"We enjoyed our stay!"

Fairfield Inn & Suites by Marriott La Crosse Downtown

10/10 Excellent

"Very clean and location is great"

Reel Paradise at Shore Slough

10/10 Excellent

"Walking in was a breath of fresh air, the view is amazing, the space is clean, there's plenty of seating, the kitchen is stocked, and the view... I don't know if anything else really mattered, except the view. The beds are comfortable, having that 1/2 bath was a bonus. we were near everything we wanted. Contacted Joan after there was a mix up in dog sitting for our granddog. I was allowed to add Finn's stay through the app! We have been coming to Northeast Iowa 30 years and this was everyone's favorite spot so far!!"

Les Carillons - Arts District Gem Large Groups Welcome! Pool! Elevator!

10/10 Excellent

"Lee Ann is a wonderful host, and my group and I thoroughly enjoyed our stay. The location is ideal with local bars and restaurants in the immediate vicinity, but it's still walkable to Bourbon St and the Superdome. The house is spacious and amenities like towels and shampoo were plentiful. Pool access was easy and the leftover sunscreen and festive hats were much appreciated. We would absolutely stay here again."

More cheap stays in Great River Road

Hotel Moab Downtown

182 S Main St Moab UT

CA $111

CA $130 total

Nov 9 - Nov 10

includes taxes & fees

8.4/10 Very good! (1,406 reviews)

Motel 6 Anaheim Maingate

Anaheim CA

CA $126

CA $148 total

Nov 2 - Nov 3

includes taxes & fees

8/10 Very good! (6,951 reviews)

Two Trees Inn

240 Indiantown Rd Mashantucket CT

CA $144

CA $166 total

Oct 21 - Oct 22

includes taxes & fees

Hampton Inn Chicago Downtown/Magnificent Mile

160 E Huron Street Chicago IL

CA $155

CA $184 total

Nov 2 - Nov 3

includes taxes & fees

8/10 Very good! (1,672 reviews)

Best Western Plus Stovall's Inn

1110 W Katella Ave Anaheim CA

CA $226

CA $265 total

Oct 27 - Oct 28

includes taxes & fees

Grand Canyon Hotel and Suites

226 Hwy 64 Grand Canyon AZ

CA $288

CA $326 total

Nov 15 - Nov 16

includes taxes & fees

Find hotels in Great River Road from CA $117

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Great River Road

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Great River Road hotels

1. AmericInn by Wyndham Prairie du Chien

2. Fairfield Inn & Suites by Marriott La Crosse Downtown

3. Days Inn by Wyndham Lake Village

4. Drury Plaza Hotel St. Louis at the Arch

5. Pear Tree Inn St. Louis Near Union Station

6. Hyatt Regency St. Louis at The Arch

7. Drury Plaza Hotel St. Louis Union Station

8. Clayton Plaza Hotel & Extended Stay

9. Wingate by Wyndham St. Louis Airport

10. The Cheshire

11. Hyatt Select St. Louis Airport

12. Moonrise Hotel

13. The Knight Center at Washington University

14. Treasure Island Resort & Casino

15. Pear Tree Inn St. Louis Airport

16. Hyatt Place Minneapolis Airport-South

17. Drury Inn & Suites St. Louis O'Fallon, IL

18. Cambria Hotel Bloomington Mall of America Minneapolis Airport

19. Irish Cottage Inn & Suites

20. Holiday Inn Express & Suites Mall of America - MSP Airport by IHG

Learn more about Great River Road

Top Great River Road Hotel Reviews

AmericInn by Wyndham Prairie du Chien

Fairfield Inn & Suites by Marriott La Crosse Downtown

Reel Paradise at Shore Slough

Les Carillons - Arts District Gem Large Groups Welcome! Pool! Elevator!

More cheap stays in Great River Road

Hotel Moab Downtown

Motel 6 Anaheim Maingate

Two Trees Inn

Hampton Inn Chicago Downtown/Magnificent Mile

Best Western Plus Stovall's Inn

Grand Canyon Hotel and Suites

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