Title: Pythagorio Vacation Packages & Trips 2026 from CA $2,003 | Expedia.ca [Hotels in Pythagorio](https://expedia.ca/Pythagorio-Hotels.d6143006.Travel-Guide-Hotels)[Vacation Rentals in Pythagorio](https://expedia.ca/Pythagorio-Vacation-Rentals.d6143006.Travel-Guide-VacationRentals)[Flights to Pythagorio](https://expedia.ca/Cheap-Flights-To-Pythagorio.d6143006.Travel-Guide-Flights)[Things to do in Pythagorio](https://expedia.ca/Things-To-Do-In-Pythagorio.d6143006.Travel-Guide-Activities)[Pythagorio Car Rentals](https://expedia.ca/Car-Rentals-In-Pythagorio.d6143006.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Pythagorio Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place #### Your Pythagorio Vacation Book a Pythagorio vacation package and focus on what counts — having some fun. This means no more planning stresses, just lots more time to uncover the best parts of this interesting city, such as its ancient history and coastal scenery. Make your trip to Pythagorio even more fun by going sightseeing. [Pythagoreion](https://www.expedia.ca/Pythagoreion-Greece.d6107186.Vacation-Attraction), [Samos Pythagorion Archaeological Museum](https://www.expedia.ca/Samos-Pythagorion-Archaeological-Museum-Greece.d6324619.Vacation-Attraction) and [Glicorisa Beach](https://www.expedia.ca/Glicorisa-Beach-Samos.d6231185.Vacation-Attraction) are among the most popular attractions worth exploring. Don't put off exploring this city any longer. Your perfect Pythagorio vacation is just a few clicks away with Expedia. ## Top Pythagorio Vacation Deals Price found within the past 48 hours. Click for updated prices. ![Anthemis Hotel](https://images.trvl-media.com/lodging/7000000/6850000/6846400/6846359/f9fdf73e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Anthemis Hotel CA $2,003 per person Mar 15 - Mar 21 found 1 day ago Roundtrip non-stop flight included Toronto (YYZ) to Samos (SMI) 9/10 Wonderful! (34 reviews) The room was cheap because it was off season. It was clean. I was one of only few guests. Close to hit springs. But no coffee, breakfast available except one restaurant in Therma. Pretty good value overall. Reviewed on Nov 16, 2025 ## Pythagorio Beach Vacation Listen to the sound of waves crashing onto the shore and look out over the shimmering waters during your Pythagorio vacation. If you need a break from everyday life, a trip to Pythagorio will work wonders. We have a great range of Pythagorio vacation packages to pick from. Lock in one near Glicorisa Beach, just 2 kilometres from the downtown area, and live out your vacation fantasies without hurting your budget. ## Things You Should Know About Pythagorio - Book one of our [Pythagorio beach hotels](https://www.expedia.ca/d6143006-tBeachHotel.Travel-Guide-Filter-Hotels?lang=en&rfrr=ATG.LP.BodyContent) to appreciate this destination at its very best. Dip a toe in the water and watch some gorgeous sunsets just steps from your front door. - Take a look at [Hotel Katerina - Top Seaview Studio Potokaki](https://www.expedia.ca/Samos-Hotels-Hotel-Katerina-Top-Seaview-Studio-Potokaki.h57518729.Hotel-Information) and [Nisea Hotel Samos](https://www.expedia.ca/Samos-Hotels-Nisea-Hotel-Samos.h74898295.Hotel-Information). These quality hotels could just be ideal for your stay in Pythagorio. - Approximately 1,250 people live in Pythagorio. If you want advice about things to see and do, why not strike up a conversation with some of the friendly locals? Our [Pythagorio things to do page](null) is also a great source of info. - Glicorisa Beach, Panagia Spiliani Monastery and Monastery of Panagia Spiliani are some great attractions that should be on your travel agenda. With our Pythagorio vacation deals, you'll have more money in your back pocket to explore. ## Ready to book your vacation to Pythagorio? Choose your dates ## Pythagorio Hotel Deals ![Casa Cook Samos](https://images.trvl-media.com/lodging/73000000/72990000/72988800/72988785/d2773c4f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Casa Cook Samos Potokaki, Pythagorion Samos 9.4/10 Exceptional! (95 reviews) Clean and modernly decorated rooms with all the facilities Reviewed on Oct 31, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=20%2F02%2F2026&endDate=21%2F02%2F2026&selected=72988785&PinnedHotelID=72988785&HadPinnedHotel=true®ionId=6143006) [](https://expedia.ca/Hotel-Search?startDate=20%2F02%2F2026&endDate=21%2F02%2F2026&selected=72988785&PinnedHotelID=72988785&HadPinnedHotel=true®ionId=6143006) ![ Doryssa Lithos Hotel](https://images.trvl-media.com/lodging/42000000/41460000/41452800/41452789/5cb3ffd2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Doryssa Lithos Hotel Pythagorion Samos 9.6/10 Exceptional! (25 reviews) This property was ideally located above the port of pythagorion. Service was super friendly, staff charming with wonderful breakfasts by the pool included. They work hard to keep the property spotless and we'll maintained. Highly recommend. Reviewed on Oct 13, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=20%2F02%2F2026&endDate=21%2F02%2F2026&selected=41452789&PinnedHotelID=41452789&HadPinnedHotel=true®ionId=6143006) [](https://expedia.ca/Hotel-Search?startDate=20%2F02%2F2026&endDate=21%2F02%2F2026&selected=41452789&PinnedHotelID=41452789&HadPinnedHotel=true®ionId=6143006) ![Doryssa Theorem Hotel](https://images.trvl-media.com/lodging/91000000/90870000/90861800/90861756/fb6ac4e4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Doryssa Theorem Hotel Pythagoreio Samos Samos Island 9.4/10 Exceptional! (81 reviews) Absolutely wonderful hotel - wish we could have stayed longer. Perfect location, beautiful room, breakfast was delicious and staff very helpful. Highly recommend. Reviewed on Oct 8, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=20%2F02%2F2026&endDate=21%2F02%2F2026&selected=90861756&PinnedHotelID=90861756&HadPinnedHotel=true®ionId=6143006) [](https://expedia.ca/Hotel-Search?startDate=20%2F02%2F2026&endDate=21%2F02%2F2026&selected=90861756&PinnedHotelID=90861756&HadPinnedHotel=true®ionId=6143006) [See all 304 properties in Pythagorio](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=07%2F02%2F2026&endDate=08%2F02%2F2026®ionId=6143006) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ### Discover the most popular places to visit in Pythagorio #### Monastery of Panagia Spiliani Find out about the history of Pythagorio when you take a trip to Monastery of Panagia Spiliani. Wander the beaches and seaside in the area. [](https://expedia.ca/Monastery-Of-Panagia-Spiliani-Samos.d6329689.Vacation-Attraction) ### What to do in Pythagorio ![Jeeps](https://mediaim.expedia.com/localexpert/2706454/00eadccb-fe3f-4d6c-a4c1-fff517870346.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Jeep Safari to National Park From Kusadasi Port / Hotels CA $112 per adult [](https://expedia.ca/things-to-do/jeep-safari-to-national-park-from-kusadasi-port-hotels.a2706454.activity-details) ![Stand Up Paddle Boarding Tour in Turkey](https://mediaim.expedia.com/localexpert/49325978/cd14f695-48d5-4978-8308-b46e31ef9bfd.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Stand Up Paddle Boarding Tour in Turkey CA $97 per traveller [](https://expedia.ca/things-to-do/stand-up-paddle-boarding-tour-in-turkey.a49325978.activity-details) [See all activities in Pythagorio](https://expedia.ca/things-to-do/search?rid=6143006) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app