Prairie City Vacation Packages

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Your Prairie City Vacation

Take the hassle out of planning your next great adventure with a Prairie City vacation package. Whether you've come for its history, food or something else, there's an inexhaustible array of experiences to be had. Neal Smith National Wildlife Refuge is one of the famous attractions to include on your itinerary during a trip to Prairie City. Whoever you're escaping with and whatever your bank balance, your dream Prairie City vacation is just a few clicks away with Expedia.

Top Prairie City Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Qube Hotel
Hyatt Place West Des Moines Jordan Creek
Hotel Fort Des Moines, Curio Collection by Hilton
Hilton Des Moines Downtown
Hampton Inn West Des Moines Lake Drive

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Prairie City Hotel Deals

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
The price is CA $204 per night from Apr 15 to Apr 16
CA $204
CA $229 total
Apr 15 - Apr 16
includes taxes & fees
9.6/10 Exceptional! (1,112 reviews)
Staff, vallet, and room service was amazing!

Reviewed on Apr 1, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
The price is CA $147 per night from Apr 15 to Apr 16
CA $147
CA $165 total
Apr 15 - Apr 16
includes taxes & fees
9.4/10 Exceptional! (1,001 reviews)
The breakfast menu was awesome! Waffles, fresh fruit, eggs-small scrambled and hard boiled, bacon, toast, juices, coffee and more! Best continental I’ve seen in awhile! The hotel was spotless, as was our room! Excellent and all staff was very cheerful and helpful!! Our dog loved it there too!!

Reviewed on Mar 30, 2026

Home2 Suites by Hilton Des Moines at Drake University
Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
The price is CA $212 per night from Apr 4 to Apr 5
CA $212
CA $237 total
Apr 4 - Apr 5
includes taxes & fees
9.8/10 Exceptional! (1,057 reviews)
The staff was friendly. The hotel was clean. Breakfast was great. Beautiful lobby. Would definitely go again!

Reviewed on Apr 1, 2026

Des Lux Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.