Title: Panama Vacation Packages & Trips 2026 | Expedia.ca [Hotels in Panama](https://expedia.ca/Panama-Hotels.d553248634983330837.Travel-Guide-Hotels)[Vacation Rentals in Panama](https://expedia.ca/Panama-Vacation-Rentals.d553248634983330837.Travel-Guide-VacationRentals)[Panama Car Rentals](https://expedia.ca/Car-Rentals-In-Panama.d553248634983330837.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Panama Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Ready to book your vacation to Panama? Choose your dates ## Panama Hotel Deals ![Cobblestone Inn & Suites - Avoca](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474954/0ad7aa10_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cobblestone Inn & Suites - Avoca 7013 N Chestnut St Avoca IA Fully refundableReserve now, pay when you stay 8.6/10 Excellent! (665 reviews) Room was clean. Quiet stay. Breakfast options were good for the price. Reviewed on Jan 30, 2026 [Get rates](https://expedia.ca/Hotel-Search?startDate=21%2F02%2F2026&endDate=22%2F02%2F2026&selected=8474954&PinnedHotelID=8474954&HadPinnedHotel=true®ionId=553248634983330837) [](https://expedia.ca/Hotel-Search?startDate=21%2F02%2F2026&endDate=22%2F02%2F2026&selected=8474954&PinnedHotelID=8474954&HadPinnedHotel=true®ionId=553248634983330837) ![Cobblestone Inn & Suites - Denison Majestic Hills](https://images.trvl-media.com/lodging/8000000/7770000/7765700/7765653/d9a21b2e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cobblestone Inn & Suites - Denison Majestic Hills 2511 Boulders Drive Denison IA Fully refundableReserve now, pay when you stay 9.4/10 Exceptional! (256 reviews) Room was clean and comfy Reviewed on Jan 16, 2026 [Get rates](https://expedia.ca/Hotel-Search?startDate=21%2F02%2F2026&endDate=22%2F02%2F2026&selected=7765653&PinnedHotelID=7765653&HadPinnedHotel=true®ionId=553248634983330837) [](https://expedia.ca/Hotel-Search?startDate=21%2F02%2F2026&endDate=22%2F02%2F2026&selected=7765653&PinnedHotelID=7765653&HadPinnedHotel=true®ionId=553248634983330837) ![Econo Lodge Inn & Suites Walnut](https://images.trvl-media.com/lodging/1000000/870000/869100/869015/dab41584_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Econo Lodge Inn & Suites Walnut 1614 Antique City Drivie Walnut IA Fully refundableReserve now, pay when you stay CA $87 CA $98 total Feb 21 - Feb 22 includes taxes & fees 7.2/10 Good! (320 reviews) Convenient location for an overnight stop. Limited selection at breakfast. No one at the front desk, just a card drop-box. Reviewed on Nov 22, 2025 [](https://expedia.ca/Hotel-Search?startDate=21%2F02%2F2026&endDate=22%2F02%2F2026&selected=869015&PinnedHotelID=869015&HadPinnedHotel=true®ionId=553248634983330837) [See all 23 properties in Panama](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=08%2F02%2F2026&endDate=09%2F02%2F2026®ionId=553248634983330837) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app