A large suspension bridge, industrial cranes, and a calm river.

Panama Canal Zone Vacation Rentals

Dates

November 2026

December 2026

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Our top choices for Panama Canal Zone vacation rentals

An indoor swimming pool with a clear water surface, surrounded by rocks and potted plants.

1. La Palma Experience

Amador

Juan Luis Perez

CA $106 total

includes taxes & fees

Nov 18 - Nov 19

A dining table with wicker chairs, two vases, and a window with blinds.

2. Former Barracks of the U.S. Army

Panamá

Kermit S.

CA $122 total

includes taxes & fees

Nov 9 - Nov 10

A bedroom with a large bed, a nightstand, a lamp, and a view of a balcony with a cityscape.

3. Private 3-Bedroom Apartment at the Golf Course with Pool 301

Cocoli

CA $301 total

includes taxes & fees

Nov 9 - Nov 10

A room with a dark grey sofa, two white chairs, a glass coffee table, and a large potted plant.

4. Casa Randa: 6 Ensuite Bedrooms near the Panama Canal

Panamá

Robin S.

CA $579 total

includes taxes & fees

Nov 9 - Nov 10

A swimming pool adjacent to a building with a balcony and stairs leading to an upper level.

5. Jacuzy, pool and lake at the same house.

Colon

Sandy F.

CA $92 total

includes taxes & fees

Dec 1 - Dec 2

A beachside lounge area with sun loungers and a thatched umbrella, palm trees, and a white fence.

6. Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.

Vacamonte

Cynthia

CA $47 total

includes taxes & fees

Nov 9 - Nov 10

A modern living room with a large sliding glass door leading to a balcony, a flat-screen TV, and a grey sofa.

7. The Hub by Boutique Apartments

San Francisco

CA $243 total

includes taxes & fees

Nov 17 - Nov 18

A rooftop swimming pool with a city skyline view, surrounded by modern buildings.

8. Loom by Boutique Apartments

San Francisco

CA $249 total

includes taxes & fees

Nov 9 - Nov 10

A rooftop pool with a city view, lounge chairs, and a clear sky.

9. Corporate Stays Arcadia | Executive Furnished Apartments

Costa del Este

Howard

CA $197 total

includes taxes & fees

Nov 22 - Nov 23

A modern outdoor swimming pool with a clear view of a tall building in the background.

10. Dovle Residences by HMS-Preferred Member

San Francisco

Patrick

CA $201 total

includes taxes & fees

Nov 9 - Nov 10

A rooftop pool area with lounge chairs and a table, overlooking a cityscape with tall buildings.

11. Boutique Apartments Panama

Bella Vista

Kirwan

CA $198 total

includes taxes & fees

Nov 9 - Nov 10

A modern living room with a sofa, a TV, a small table, and a balcony with a view of the city.

12. Living 73 Panamá by Boutique Apartments

San Francisco

Lorenz

CA $267 total

includes taxes & fees

Nov 10 - Nov 11

A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

13. Boutique Apartments Panamá Coco del Mar

San Francisco

purabi

CA $260 total

includes taxes & fees

Nov 30 - Dec 1

A swimming pool with a city skyline in the background.

14. Modern Design Apartments near Sortis

Bella Vista

Kareem

CA $98 total

includes taxes & fees

Nov 10 - Nov 11

A modern cabin with a sloped roof, surrounded by trees, and a gravel path leading to the entrance.

15. Tiny Cabin

Panamá

CA $208 total

includes taxes & fees

Nov 12 - Nov 13

A rooftop pool with a view of the cityscape, lounge chairs, and potted plants.

16. Casco View Apartments & Rooftop Pool

Santa Ana

CA $132 total

includes taxes & fees

Nov 9 - Nov 10

A rooftop pool with lounge chairs, a modern building with a reflective facade, and a clear blue sky.

17. Yoo Panama Luxury Ocean View Apartment

Bella Vista

Mark

CA $193 total

includes taxes & fees

Nov 11 - Nov 12

A tall, modern skyscraper with a grid-like facade and numerous windows.

18. Luxury City View Apartments at Worldwide

Bella Vista

Denesha

CA $111 total

includes taxes & fees

Nov 24 - Nov 25

A modern hotel lobby with a marble staircase, seating areas, and a large mirror reflecting the space.

19. Torres de Alba Hotel & Suites

Bella Vista

Patricia

CA $137 total

includes taxes & fees

Dec 9 - Dec 10

A bedroom with a bed, two wall-mounted lights, a ceiling fan, and a wooden floor.

20. Refugio Frente al Mar Vista Venao

Veracruz

Joanna

CA $101 total

includes taxes & fees

Nov 9 - Nov 10

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Find vacation rentals that suit your style

Top Panama Canal Zone Hotel Reviews

A hotel courtyard with a central lawn, surrounded by buildings with balconies and outdoor seating areas.

Hotel La Compañía Casco Antiguo

Casco Viejo

10/10 Excellent

Darija

Villa Caprichosa

Taboga

10/10 Excellent

The most romantic hotel I have ever been to. I felt like I stayed at an Italian villa. My husband and I stayed for a week and enjoyed everything about the hotel. The staff were amazing, the gardens were beautiful and the restaurant was top notch. There is not a lot to do on the island And not a lot of shops to buy necessities so make sure that you bring everything you need with you. If you need a break to get away from it all this is your place.

Helen

A balcony with a table, chairs, and a view of a city skyline across a body of water.

Sofitel Legend Casco Viejo, Panama City

Casco Viejo

10/10 Excellent

My stay at Sofitel Legend in Casco Antiguo was exceptional. The property is beautiful, the historic location adds so much to the experience, and the standard of service matches what you expect from a five-star hotel. What made the stay memorable, however, was the staff. Everyone was welcoming and attentive, with a genuine sense of hospitality. A special mention to Roberto, who was outstanding. He was personable, thoughtful and always seemed to know when assistance was needed without being...

Helen

A resort with a pool area, lounge chairs, and a view of a bridge at night.

Radisson Hotel Panama Canal

Amador

10/10 Excellent

GISELA

A swimming pool with a water feature, surrounded by plants and seating areas.

Holiday Inn Panama Canal by IHG

Panama City

10/10 Excellent

I just had to stay there for one night to travel the next morning to Bocas Del Toro. Receptionist was very friendly and helpful. The upper floor was under construction but I did not hear a thing. TV was first not working but within no time an employee showed up, took the remote, came back with different remote and it worked well. Breakfast next morning is dangerous because it is sooo good. You don’t want to stop putting the great food in your mouth ;-) If I have to stay again overnight in...

Karsten

A multi-story hotel with balconies, air conditioning units, and a street in front with parked cars and traffic cones.

La Cubana Colón

Cristobal

8/10 Good

Martin

A poolside area with lounge chairs and a covered seating area, reflecting the pool and surrounding structures.

Summit Rainforest Golf Resort & All Inclusive

Panama City

10/10 Excellent

I first went there in 2012 when the hotel was almost new and it's was just amazing. I came back 3 years after and it had shown a lack of maintenance and I mentioned it in my evaluation, but I still loved the place. So this year was my third time and they have really put some resources in improving the overall comfort of the place. To make it short, there is not a better place in Panama for romance: 1-the location is spectacular if you are nature lover. It is surrounded by a dense tropical...

Raphael

A swimming pool with a tiled deck, surrounded by lush greenery and two white lounge chairs.

Panama Canal Inn

Panama City

8/10 Good

Anonymous traveller

A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.

Hyatt Regency Panama City

Bella Vista

10/10 Excellent

Greg

A rooftop pool area with a modern building, outdoor seating, and a view of high-rise buildings in the background.

Ramada Plaza by Wyndham Panama Punta Pacifica

San Francisco

10/10 Excellent

Praveen

A rooftop terrace with a hot tub, wooden deck, outdoor seating, and a view of a cityscape including a clock tower.

Amarla Boutique Hotel Casco Viejo Adults Only

Casco Viejo

10/10 Excellent

Edward

Find out more about Panama Canal Zone

Everything you need to know about Panama Canal Zone vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panama Canal Zone vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama Canal Zone vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Panama Canal Zone vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panama Canal Zone. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Panama Canal Zone vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Panama Canal Zone vacation rentals we have selected for you start as low as CA $30 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Panama Canal Zone rentals

At Expedia, we put the best Panama Canal Zone vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Panama Canal Zone rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama Canal Zone vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama Canal Zone. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Panama Canal Zone Vacation Rentals

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Panama Canal Zone vacation rentals

1. La Palma Experience

2. Former Barracks of the U.S. Army

3. Private 3-Bedroom Apartment at the Golf Course with Pool 301

4. Casa Randa: 6 Ensuite Bedrooms near the Panama Canal

5. Jacuzy, pool and lake at the same house.

6. Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.

7. The Hub by Boutique Apartments

8. Loom by Boutique Apartments

9. Corporate Stays Arcadia | Executive Furnished Apartments

10. Dovle Residences by HMS-Preferred Member

11. Boutique Apartments Panama

12. Living 73 Panamá by Boutique Apartments

13. Boutique Apartments Panamá Coco del Mar

14. Modern Design Apartments near Sortis

15. Tiny Cabin

16. Casco View Apartments & Rooftop Pool

17. Yoo Panama Luxury Ocean View Apartment

18. Luxury City View Apartments at Worldwide

19. Torres de Alba Hotel & Suites

20. Refugio Frente al Mar Vista Venao

Find vacation rentals that suit your style

Top Panama Canal Zone Hotel Reviews

Hotel La Compañía Casco Antiguo

10/10 Excellent

Find out more about Panama Canal Zone

Panama Canal Zone vacation rentals: An excellent choice for every season

How to find incredible deals on Panama Canal Zone rentals