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Our top choices for Panacea vacation homes
1. Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat
Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing RetreatPanacea
9.8 out of 10, Exceptional, (28 reviews)
"Great place to stay while fishing"
Benjamin S.
The price is CA $185
CA $429 total
includes taxes & fees
Nov 16 - Nov 17
2. Tiny Tides Waterfront Cottage
Tiny Tides Waterfront CottagePanacea
10.0 out of 10, Exceptional, (15 reviews)
"What a perfect escape! We thoroughly enjoyed our stay at Tiny Tides. The cozy, comfortable vibe, the peaceful location, and the easy access to everything made our trip truly special. We had a fantastic time and will definitely be back soon!"
Jason W.
The price is CA $225
CA $518 total
includes taxes & fees
Nov 17 - Nov 18
3. Private beach winter escape on the bay with fishing and kayaks
Private beach winter escape on the bay with fishing and kayaksPanacea
10.0 out of 10, Exceptional, (5 reviews)
"Had a great stay! We would book here again."
Ashley D.
The price is CA $287
CA $662 total
includes taxes & fees
Nov 15 - Nov 16
4. Point & Paddle Waterfront Retreat @Alligator Point
Point & Paddle Waterfront Retreat @Alligator PointAlligator Point
10.0 out of 10, Exceptional, (2 reviews)
"We really enjoyed the place. It was quiet, cozy, and perfect for a quick getaway with our family. I would highly recommend others checking this place out and tho we don’t visit the area much we would love staying here again!"
Scott A.
The price is CA $271
CA $635 total
includes taxes & fees
Nov 15 - Nov 16
5. Breezy Home w/ Grills, Pool & Beach Access!
Breezy Home w/ Grills, Pool & Beach Access!Sopchoppy
10.0 out of 10, Exceptional, (28 reviews)
"Great property. House was very clean and well stocked. Neighborhood was very quiet and peaceful. Enjoyed our stay and would love to stay again. "
Lisa M.
The price is CA $313
CA $787 total
includes taxes & fees
Nov 24 - Nov 25
6. The Best Beach-Front House “Get-A-Way” in Florida
The Best Beach-Front House “Get-A-Way” in FloridaPanacea
10.0 out of 10, Exceptional, (101 reviews)
"Wonderful place on the beach. My sister and I had a great time here. I especially love that the beach is dog-friendly!"
Lisa R.
The price is CA $410
CA $912 total
includes taxes & fees
Nov 15 - Nov 16
7. Dock, Boat Lift & Golf Cart on Alligator Point
Dock, Boat Lift & Golf Cart on Alligator PointAlligator Point
10.0 out of 10, Exceptional, (2 reviews)
"Lovely place! Interesting area and wished we had more time there."
Ann G.
The price is CA $473
CA $1,068 total
includes taxes & fees
Nov 28 - Nov 29
8. NEW - St. Teresa Beach Escape w/ Private Beach Acc
NEW - St. Teresa Beach Escape w/ Private Beach AccLanark Village
10.0 out of 10, Exceptional, (2 reviews)
"This house was very comfortable, beds, pillows, towels, sofa, etc. Quiet, peaceful, serene setting. Close proximity to beach and the pool was an added bonus!Thank you for a very enjoyable stay!"
Debra M.
The price is CA $448
CA $1,081 total
includes taxes & fees
Nov 15 - Nov 16
9. BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.
BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.Panacea
9.6 out of 10, Exceptional, (95 reviews)
"Charming beach house just steps away from the beach. The beach was quiet which is a great alternative to crowded beaches. Robin was very responsive and helpful. Would love to come back!"
cyle w.
The price is CA $511
CA $1,126 total
includes taxes & fees
Nov 23 - Nov 24
10. 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
7 Bedroom Beach House with POOL!! Gulf Front and Bay FrontAlligator Point
10.0 out of 10, Exceptional, (131 reviews)
"We had an amazing week. Best equipped home we have ever stayed. The privacy and peacefulness was just want we needed. Host was very responsive."
Tracy G.
The price is CA $1,284
CA $3,202 total
includes taxes & fees
Nov 21 - Nov 22
11. Dragonfly on the Canal Golf cart included!
Dragonfly on the Canal Golf cart included!Crawfordville
10.0 out of 10, Exceptional, (65 reviews)
"Very welcoming community and lived up to its name with being fully dragonfly & beach themed. Wish we could have fully enjoyed the outside amenities, but the weather had other plans."
Allison
The price is CA $207
CA $444 total
includes taxes & fees
Nov 15 - Nov 16
12. Waterfront -Beautiful sunsets, great fishing, scalloping & bird watching
Waterfront -Beautiful sunsets, great fishing, scalloping & bird watchingCrawfordville
10.0 out of 10, Exceptional, (58 reviews)
"Nice and relaxing"
chad c.
The price is CA $250
CA $395 total
includes taxes & fees
Nov 15 - Nov 16
13. Relax at Shell Point Beach! Bring your boat to park at the dock.
Relax at Shell Point Beach! Bring your boat to park at the dock.Crawfordville
9.2 out of 10, Wonderful, (11 reviews)
"We have rented this place several times and the place is always spotless and the communication with the host is excellent! Will stay here again!"
Anonymous traveller
The price is CA $256
CA $699 total
includes taxes & fees
Nov 22 - Nov 23
14. Wedding & Event Residence Sopchoppy 5 bedrooms/Honeymoon Suite
Wedding & Event Residence Sopchoppy 5 bedrooms/Honeymoon SuiteSopchoppy
The price is CA $7,061
CA $8,213 total
includes taxes & fees
Nov 18 - Nov 19
15. The Oyster Bed- Riverwalk Cottages Unit 204 B
The Oyster Bed- Riverwalk Cottages Unit 204 BCarrabelle
9.8 out of 10, Exceptional, (51 reviews)
"Loved that the property was pet friendly! Enjoyed the stay here as it is close proximity to shopping,dining and sight-seeing!"
Tom K.
The price is CA $164
CA $321 total
includes taxes & fees
Nov 16 - Nov 17
16. The Sand Dollar - Riverwalk Cottages Unit 204 A
The Sand Dollar - Riverwalk Cottages Unit 204 ACarrabelle
10.0 out of 10, Exceptional, (31 reviews)
"Great location, clean cute cottage. Very comfortable."
Debi P.
The price is CA $164
CA $321 total
includes taxes & fees
Nov 16 - Nov 17
17. FISHERMAN'S PARADISE!! Cozy home 2 minutes to the Gulf
FISHERMAN'S PARADISE!! Cozy home 2 minutes to the GulfCarrabelle
9.4 out of 10, Exceptional, (3 reviews)
"Everything was as described. We had a great stay."
Jared R.
The price is CA $371
CA $586 total
includes taxes & fees
Nov 15 - Nov 16
18. Beach/Marina/Walking trails and more…
Beach/Marina/Walking trails and more…Carrabelle
10.0 out of 10, Exceptional, (4 reviews)
"Nice house, pet friendly, easy parking highly recommend. Thanks for a great vacation!"
Edward H.
The price is CA $193
CA $627 total
includes taxes & fees
Dec 11 - Dec 12
19. The Blue Crab at Riverwalk Cottages Unit 202B
The Blue Crab at Riverwalk Cottages Unit 202BCarrabelle
9.6 out of 10, Exceptional, (15 reviews)
"We enjoyed staying here."
Tammy P.
The price is CA $164
CA $324 total
includes taxes & fees
Nov 27 - Nov 28
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Panacea
Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.
Top reviews in Panacea
Best Western Wakulla Inn & Suites
Best Western Wakulla Inn & SuitesCrawfordville
10/10 Excellent
Clean room, good choice in the middle of nowhere
Detlev
