Panacea Guest Houses from CA $174

A coastal resort with beachfront villas and a clear blue sky.

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Recommended hotels in Panacea

A pink door with a window, set in a corrugated metal exterior with wooden trim.

1. The Panacea Motel

Panacea

Dashawn

CA $174 total

includes taxes & fees

Oct 25 - Oct 26

A tree silhouetted against a sunset sky, a body of water, and a snowy landscape.

2. Cozy Panacea Retreat #3 (King)

Panacea

Faith V.

CA $254 total

includes taxes & fees

Oct 21 - Oct 22

A cozy living room with a brown leather sofa, a dining table set with plates, and a view of the sea through large windows.

3. romantic get away for 2 right on the Ochlockonee river

Panacea

Laurie K.

CA $450 total

includes taxes & fees

Oct 19 - Oct 20

A covered outdoor area with a wooden deck, white furniture, and a view of the water.

4. Tiny Tides Waterfront Cottage

Panacea

Jason W.

CA $555 total

includes taxes & fees

Oct 14 - Oct 15

A modern kitchen with a wooden countertop, a built-in sink, and a dining area with a table and chairs.

5. Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat

Panacea

Benjamin S.

A wooden bench in a natural setting with a lake and trees in the background.

6. Queen Kitchenette by the Bay #16

Panacea

CA $254 total

includes taxes & fees

Oct 25 - Oct 26

7. Queen Kitchenette by the Bay #15

Panacea

CA $254 total

includes taxes & fees

Oct 25 - Oct 26

8. Queen Kitchenette by the Bay #14

Panacea

CA $254 total

includes taxes & fees

Oct 28 - Oct 29

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Top Panacea Hotel Reviews

The Best Beach-Front House “Get-A-Way” in Florida

10/10 Excellent

"Wonderful property! I was looking for a quiet, dog-friendly beach vacation rental and this was the perfect spot! Perfect for long beach walks and our dog had a blast on the beach…true water dog. Owners were very responsive and accommodating. Ate at Angelo’s and 10/10 recommend!The beach was literally in the back yard. It was so easy to just walk out back and go down to the water."

Hideaway Beach Cottage on waterfront with amazing views.

10/10 Excellent

"Booking this stay was incredibly easy. Hosts are responsive and very accommodating. Price was great, especially considering that we thought the property was even better in person. Pictures truly don’t do it justice. The small town of Panacea is a breath of fresh air. Not your typical touristy beach town. We wanted to have a slow, low stim vacation with our young kids and that’s exactly what we got. There are still enough restaurants to choose from if you want to eat out every night in the town and even more within a 20 minute drive. If you want to stay in and cook, the kitchen has plenty of room and is stocked well. Large dining table with more than enough room. The living area large and comfy. We didn’t use the second bedroom beds because our kids are still in pack and plays. Two fit in the room just fine. The master bedroom mattress was genuinely one of the most comfortable beds I’ve slept in. Screened in porch was amazing to relax in and let in 0 bugs somehow. So impressed. Our absolute favorite part though was the yard and little beach on the bay. Our kids can’t stand to be inside and they played for HOURS in the good sized yard. We watched stingrays, fish, and birds in the bay. The only thing I’d tell people to consider is that the beach can be a drive. The closest beach, Mashes Sands, had almost no shoreline so you’ll need to drive \- 20 minutes for a beach. This didn’t bother us at all. There is virtually no traffic and tons of options."

Coastal Getaway on canal-steps to the beach

10/10 Excellent

"Awesome weekend staying at this location. We was within walking distance to the beach and fishing. Loved that it had a complete bathroom downstairs when we came in from fishing all day and night. Great communication with the host. Very prompt responding to questions. Will recommend to family and friends!!"

"Somewhere In The Sun" Beachfront Cottage - Old Florida Style Hideaway

10/10 Excellent

"Great beach bungalow. Pictures don’t do it justice. Much more spacious than we anticipated. Had everything we needed. Very cute and wonderful views of the beach. Area was great for us, quiet, private, not touristy at all. We saw so many stars at night, even saw the Milky Way the first night there. Definitely recommend if you are looking for that old school small Florida beach house vibe."

Find out more about Panacea

Panacea Guest Houses information

Number of reviews	144
Accommodation	0 Guest Houses
Lowest Price	CA $174
Highest Price	CA $1,010

Frequently asked questions

What is the nightly rate for a guest house in Panacea?

Rates for Panacea guest houses vary, but travelers can find great-value prices from CA $174 with Expedia. A range of factors can affect nightly rates, such as the location, the breakfast offering, and the range of amenities. Travelers looking for a good deal should consider looking for a midweek stay, as weekend rates at Panacea guest houses tend to be higher. Remember to also use our filters to sort prices from low to high.

What's the difference between a Panacea guest house and a B&B?

A guest house in Panacea is typically a larger establishment with more rooms, offering a more hotel-like experience, and may provide additional amenities including luxury bedding. In contrast, a B&B is usually a smaller property that focuses primarily on providing a room and breakfast. A B&B is often more personal, and breakfast is typically included as part of the stay, but other services might be more limited compared to a guest house.

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Book Guest Houses in Panacea on Expedia.com

Room 1

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Treat yourself

Be picky

Check prices for these dates

Recommended hotels in Panacea

1. The Panacea Motel

2. Cozy Panacea Retreat #3 (King)

3. romantic get away for 2 right on the Ochlockonee river

4. Tiny Tides Waterfront Cottage

5. Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat

6. Queen Kitchenette by the Bay #16

7. Queen Kitchenette by the Bay #15

8. Queen Kitchenette by the Bay #14

9. Cozy Panacea Retreat #3 (King)

10. Cozy Panacea Retreat #7 (King)

11. Queen Kitchenette by the Bay #13

12. Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

13. Perfect Panacea 1 Bedroom Apt, #2

14. 09) Queen Kitchenette by the Bay

15. Queen Kitchenette by the Bay #11

16. Queen Kitchenette by the Bay #10

17. Queen Kitchenette by the Bay #8

18. Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

19. Queen Kitchenette by the Bay #17

20. The Best Beach-Front House “Get-A-Way” in Florida

Top Panacea Hotel Reviews

The Best Beach-Front House “Get-A-Way” in Florida

Great sunrise view from dining area and decks. Easy beach access.

Cozy bayfront farmhouse!

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

Lighthouse- enjoy the water, bask in the view

Hideaway Beach Cottage on waterfront with amazing views.

Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +

Coastal Getaway on canal-steps to the beach

"Somewhere In The Sun" Beachfront Cottage - Old Florida Style Hideaway

Find out more about Panacea

Panacea Guest Houses information

Frequently asked questions

Explore a world of travel with Expedia

Search Guest Houses in Panacea from CA $174

Change your mind

Treat yourself

Be picky

Check prices for these dates

Recommended hotels in Panacea

1. The Panacea Motel

2. Cozy Panacea Retreat #3 (King)

3. romantic get away for 2 right on the Ochlockonee river

4. Tiny Tides Waterfront Cottage

5. Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat

6. Queen Kitchenette by the Bay #16

7. Queen Kitchenette by the Bay #15

8. Queen Kitchenette by the Bay #14

9. Cozy Panacea Retreat #3 (King)

10. Cozy Panacea Retreat #7 (King)

11. Queen Kitchenette by the Bay #13

12. Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

13. Perfect Panacea 1 Bedroom Apt, #2

14. 09) Queen Kitchenette by the Bay

15. Queen Kitchenette by the Bay #11

16. Queen Kitchenette by the Bay #10

17. Queen Kitchenette by the Bay #8

18. Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

19. Queen Kitchenette by the Bay #17

20. The Best Beach-Front House “Get-A-Way” in Florida

Top Panacea Hotel Reviews

The Best Beach-Front House “Get-A-Way” in Florida

Find out more about Panacea

Panacea Guest Houses information

Frequently asked questions

Explore a world of travel with Expedia