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Check prices for these dates

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Sep 5 - Sep 7
In two weeks
Sep 12 - Sep 14
In one month
Sep 26 - Sep 28
In two months
Oct 24 - Oct 26

Browse Select Panacea Guest Houses

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Recommended hotels in Panacea

The Lodge at Wakulla Springs
Reception

The Lodge at Wakulla Springs

3.0 star property
9.4 out of 10, Exceptional, (977)
"We love staying here!!"
The price is CA $140
CA $157 total
includes taxes & fees
Oct 1 - Oct 2
The Lodge at Wakulla Springs
The Panacea Motel
Exterior

The Panacea Motel

2.0 star property
9.0 out of 10, Wonderful, (112)
"Needed a place for overnight on our journey. Small & quaint. Rooms are clean & have coffee, fridge & microwave . No one on property but there is an available #to call if needed. Would stay again."
The price is CA $147
CA $164 total
includes taxes & fees
Sep 1 - Sep 2
The Panacea Motel
Wildwood Inn
1 bedroom, in-room safe, desk, iron/ironing board

Wildwood Inn

3.0 star property
8.6 out of 10, Excellent, (1003)
"An enjoyable stay. Thank you."
The price is CA $160
CA $184 total
includes taxes & fees
Sep 22 - Sep 23
Wildwood Inn
Best Western Wakulla Inn & Suites
Dining

Best Western Wakulla Inn & Suites

2.5 star property
8.8 out of 10, Excellent, (917)
"We absolutely love this venue and stay here when we visit our family every year! "
The price is CA $159
CA $178 total
includes taxes & fees
Sep 16 - Sep 17
Best Western Wakulla Inn & Suites
The Anglers Basecamp! Newly remodeled 2-bedroom house in Panacea
Private kitchen

The Anglers Basecamp! Newly remodeled 2-bedroom house in Panacea

The Anglers Basecamp! Newly remodeled 2-bedroom house in Panacea
BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.
Outdoor dining

BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.

9.8 out of 10, Exceptional, (82)
"We enjoyed our stay. The house was beautiful. Very relaxing. Would stay here again."
The price is CA $369
CA $974 total
includes taxes & fees
Sep 1 - Sep 2
BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.
Bill's Bay Breeze is the perfect spot for a family vacation or a weekend getaway
Interior

Bill's Bay Breeze is the perfect spot for a family vacation or a weekend getaway

9.2 out of 10, Wonderful, (7)
"We loved our trip! Home was very cozy and the huge screened in porch was amazing! Highly recommend!"
The price is CA $217
CA $601 total
includes taxes & fees
Sep 1 - Sep 2
Bill's Bay Breeze is the perfect spot for a family vacation or a weekend getaway
Charming 2-bedroom apartment in fabulous Panacea with AC
Property grounds

Charming 2-bedroom apartment in fabulous Panacea with AC

The price is CA $157
CA $283 total
includes taxes & fees
Sep 8 - Sep 9
Charming 2-bedroom apartment in fabulous Panacea with AC
Cozy Panacea Retreat #3 (King)
Beach

Cozy Panacea Retreat #3 (King)

The price is CA $209
CA $260 total
includes taxes & fees
Sep 1 - Sep 2
Cozy Panacea Retreat #3 (King)
NEW - St. Teresa Beach Escape w/ Private Beach Acc
Fridge, microwave, oven, stovetop

NEW - St. Teresa Beach Escape w/ Private Beach Acc

The price is CA $317
CA $825 total
includes taxes & fees
Sep 2 - Sep 3
NEW - St. Teresa Beach Escape w/ Private Beach Acc
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
On the beach

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

10.0 out of 10, Exceptional, (119)
"After 29 years of Girl's trips, we have found the best equipped house ever. The kitchen had everything you needed, the games were plentiful, the bathroom and bedrooms were beautiful and fully supplied. The pool and beach equipment were all we needed. Lisa, property manager was super sweet. We had an awesome time! We will be back, God willing."
The price is CA $962
CA $2,699 total
includes taxes & fees
Sep 1 - Sep 2
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
Gulf Coast Getaway: 5BR Home with Private Dock – Keep Your Boat in the Water!
Property grounds

Gulf Coast Getaway: 5BR Home with Private Dock – Keep Your Boat in the Water!

10.0 out of 10, Exceptional, (3)
"Great house and location."
The price is CA $874
CA $1,594 total
includes taxes & fees
Sep 2 - Sep 3
Gulf Coast Getaway: 5BR Home with Private Dock – Keep Your Boat in the Water!
Panacea Cozy Retreat #4 (DQ)
1 bedroom, desk, WiFi, bed sheets

Panacea Cozy Retreat #4 (DQ)

The price is CA $242
CA $300 total
includes taxes & fees
Sep 1 - Sep 2
Panacea Cozy Retreat #4 (DQ)
Perfect Panacea 1 Bedroom Apt, #2
Property grounds

Perfect Panacea 1 Bedroom Apt, #2

The price is CA $258
CA $323 total
includes taxes & fees
Sep 1 - Sep 2
Perfect Panacea 1 Bedroom Apt, #2
Franklin Inn
1 bedroom, free WiFi, bed sheets

Franklin Inn

2.0 star property
7.8 out of 10, Good, (433)
"Food options are close and very good"
The price is CA $124
CA $138 total
includes taxes & fees
Sep 9 - Sep 10
Franklin Inn
Dragonfly on the Canal
Beach

Dragonfly on the Canal

2.0 star property
10.0 out of 10, Exceptional, (29)
"Great Place, awesome location and very clean"
The price is CA $161
CA $417 total
includes taxes & fees
Sep 1 - Sep 2
Dragonfly on the Canal
St James Bay Golf & Pickleball Resort
Outdoor pool

St James Bay Golf & Pickleball Resort

3.5 star property
9.0 out of 10, Wonderful, (352)
"The area around the resort is beautiful. it was Sunday, was supposed to have breakfast in the restaurant per its menu in the room, but it was not available. The room was not clean, but the sheets and towels were good. "
The price is CA $218
CA $241 total
includes taxes & fees
Sep 7 - Sep 8
St James Bay Golf & Pickleball Resort
The Sea Turtle at Riverwalk Cottages Unit 202A
Exterior

The Sea Turtle at Riverwalk Cottages Unit 202A

9.6 out of 10, Exceptional, (60)
"As a return guest we have always enjoyed our stay in the cottages. A for us."
The price is CA $158
CA $326 total
includes taxes & fees
Sep 1 - Sep 2
The Sea Turtle at Riverwalk Cottages Unit 202A
Enjoy Crawfordville at the Courtyard’s Oyster Cottage
Exterior

Enjoy Crawfordville at the Courtyard’s Oyster Cottage

10.0 out of 10, Exceptional, (49)
"Very clean and comfortable right in downtown Crawfordville. Close to everything. "
The price is CA $122
CA $280 total
includes taxes & fees
Sep 9 - Sep 10
Enjoy Crawfordville at the Courtyard’s Oyster Cottage
The Moorings Hotel and Marina
Exterior

The Moorings Hotel and Marina

2.5 star property
8.4 out of 10, Very good, (34)
"Nice room overlooking the water, had issues with the A/C when we first arrived but the staff took excellent care of getting it resolved and made our stay very inviting. We Will be staying here again for sure!! "
The price is CA $190
CA $210 total
includes taxes & fees
Oct 1 - Oct 2
The Moorings Hotel and Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panacea Hotel Reviews

Find out more about Panacea

Find out more about Panacea

Panacea Guest Houses information

Number of reviews
Accommodation
3 Guest Houses
Lowest Price
Highest Price

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Frequently asked questions

What is the nightly rate for a guest house in Panacea?
Rates for Panacea guest houses vary, but travelers can find great-value prices with Expedia. A range of factors can affect nightly rates, such as the location, the breakfast offering, and the range of amenities. Travelers looking for a good deal should consider looking for a midweek stay, as weekend rates at Panacea guest houses tend to be higher. Remember to also use our filters to sort prices from low to high.
What's the difference between a Panacea guest house and a B&B?
A guest house in Panacea is typically a larger establishment with more rooms, offering a more hotel-like experience, and may provide additional amenities including luxury bedding. In contrast, a B&B is usually a smaller property that focuses primarily on providing a room and breakfast. A B&B is often more personal, and breakfast is typically included as part of the stay, but other services might be more limited compared to a guest house.