Title: Book the Best Odessa SPA Resorts from CA $138 - Spa Hotels in Odessa, FL | Expedia.ca [Odessa Travel Guide](https://expedia.ca/Odessa.dx6341356)[Hotels in Odessa](https://expedia.ca/Odessa-Hotels.d6341356.Travel-Guide-Hotels)[Vacation Rentals in Odessa](https://expedia.ca/Odessa-Vacation-Rentals.d6341356.Travel-Guide-VacationRentals)[Things to do in Odessa](https://expedia.ca/Things-To-Do-In-Odessa.d6341356.Travel-Guide-Activities)[Odessa Car Rentals](https://expedia.ca/Car-Rentals-In-Odessa.d6341356.Car-Rental-Guide)[Odessa Vacation Packages](https://expedia.ca/Odessa.d6341356.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/pool.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Odessa, FL from CA $138 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Odessa Spa Hotels Tonight [Dec 26 - Dec 27](https://www.expedia.ca/Hotel-Search?regionId=6341356&startDate=2025-12-26&endDate=2025-12-27&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 27 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6341356&startDate=2025-12-27&endDate=2025-12-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6341356&startDate=2025-12-26&endDate=2025-12-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6341356&startDate=2026-01-02&endDate=2026-01-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Odessa hotels with a spa ![Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/30000000/29650000/29643000/29642928/a9443a2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/30000000/29650000/29643000/29642928/31dc57a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/30000000/29650000/29643000/29642928/a1b8c4f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/30000000/29650000/29643000/29642928/55c93de1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Tampa South [](https://www.expedia.ca/Tampa-Hotels-Sleep-Inn-Suites-Tampa-South.h29642928.Hotel-Information) Sun Bay South 9.0/10 Wonderful (1003) "The lady that checked us in was wonderful with excellent customer service. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maricel CA $121 CA $138 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/Tampa-Hotels-Sleep-Inn-Suites-Tampa-South.h29642928.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/101000000/100700000/100698900/100698855/5e9ba401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/101000000/100700000/100698900/100698855/2eb32b9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100700000/100698900/100698855/cd18684c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/101000000/100700000/100698900/100698855/2b367b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grant Street Inn, an Ascend Collection Hotel [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Grant-Street-Inn.h100698855.Hotel-Information) Downtown Dunedin 9.6/10 Exceptional (213) "Room and hotel area very clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) maureen CA $154 CA $174 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Grant-Street-Inn.h100698855.Hotel-Information) ![Couples treatment rooms, steam room, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/16000000/15920000/15914400/15914352/83a6903a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/16000000/15920000/15914400/15914352/1907db38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/16000000/15920000/15914400/15914352/3e998290.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/16000000/15920000/15914400/15914352/13b2550b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Grand Clearwater Beach [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Wyndham-Grand-Clearwater-Beach.h15914352.Hotel-Information) Clearwater Beach 9.4/10 Exceptional (2937) "Everything about this stay was AMAZING!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nikki CA $281 CA $372 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Wyndham-Grand-Clearwater-Beach.h15914352.Hotel-Information) ![6 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/16700/16668/363b5cc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/20000/16700/16668/22de563f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/16700/16668/173c1756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/1000000/20000/16700/16668/12e5d1c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Innisbrook Resort [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Innisbrook-Resort.h16668.Hotel-Information) Palm Harbor 8.4/10 Very good (1001) "Beautiful property Loved shuttle service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katherine CA $212 CA $309 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Innisbrook-Resort.h16668.Hotel-Information) ![2 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/8200/8126/3a68ae49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/8200/8126/161d4018.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/8200/8126/d1202de5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sport court](https://images.trvl-media.com/lodging/1000000/10000/8200/8126/3ca9ef49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Saddlebrook Resort [](https://www.expedia.ca/Tampa-Hotels-Saddlebrook-Golf-Resort-And-Spa.h8126.Hotel-Information) Wesley Chapel South 8.0/10 Very good (5) CA $245 CA $315 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Tampa-Hotels-Saddlebrook-Golf-Resort-And-Spa.h8126.Hotel-Information) ![Couples treatment rooms, steam room, body treatments, hydrotherapy](https://images.trvl-media.com/lodging/1000000/30000/28100/28023/a0ebc551.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds (Gulf View)](https://images.trvl-media.com/lodging/1000000/30000/28100/28023/w3839h2744x0y0-89f18d74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28100/28023/da46d3f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/28100/28023/e311c0c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Clearwater Beach Resort & Spa [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Hilton-Clearwater-Beach-Resort-Spa.h28023.Hotel-Information) Clearwater Beach 8.0/10 Very good (2370) "Great hotel, awesome views, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn CA $212 CA $294 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Hilton-Clearwater-Beach-Resort-Spa.h28023.Hotel-Information) ![Sauna, hot tub, steam room, body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/20000/14200/14189/53f0efd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/14200/14189/67b1ebff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/14200/14189/a46aaa05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/14200/14189/c4ab1506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Opal Sands Resort [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Opal-Sands-Resort.h14189.Hotel-Information) Clearwater Beach 9.4/10 Exceptional (1176) "Another great stay at a wonderful hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gerald CA $403 CA $503 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Opal-Sands-Resort.h14189.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, hot springs](https://images.trvl-media.com/lodging/1000000/30000/20400/20378/acfc999c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/30000/20400/20378/6d9b5794.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/20400/20378/2db79476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/20400/20378/e40cafd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Safety Harbor Resort & Spa Trademark Collection by Wyndham [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Safety-Harbor-Resort-Spa-Trademark-Collection-By-Wyndham.h20378.Hotel-Information) Safety Harbor 8.4/10 Very good (1001) "The pool is beautiful and the staff at the Tiki Bar and Grill are great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole CA $301 CA $374 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Safety-Harbor-Resort-Spa-Trademark-Collection-By-Wyndham.h20378.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/122000000/121420000/121418000/121417969/5599cde0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/122000000/121420000/121418000/121417969/313fed8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/122000000/121420000/121418000/121417969/54349357.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/122000000/121420000/121418000/121417969/47fe1ef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blue Wave Suites [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Blue-Wave-Suites.h121417969.Hotel-Information) Clearwater Beach CA $365 CA $412 total includes taxes & fees Jan 6 - Jan 7, 2026 [](https://www.expedia.ca/St-Petersburg-Clearwater-Hotels-Blue-Wave-Suites.h121417969.Hotel-Information) ![Hair salon](https://images.trvl-media.com/lodging/2000000/1050000/1044200/1044188/1c190f08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![9 restaurants, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/2000000/1050000/1044200/1044188/c2674d64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, open 8:00 AM to 8:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/2000000/1050000/1044200/1044188/6efee43c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/2000000/1050000/1044200/1044188/3904862c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Seminole Hard Rock Hotel & Casino Tampa [](https://www.expedia.ca/Tampa-Hotels-Seminole-Hard-Rock-Hotel-Casino-Tampa.h1044188.Hotel-Information) Tampa 8.8/10 Excellent (1325) "Beautiful hotel comfy beds very clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) karen CA $430 CA $526 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Tampa-Hotels-Seminole-Hard-Rock-Hotel-Casino-Tampa.h1044188.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-09&endDate=2026-01-10®ionId=6341356&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Odessa ### Top Odessa attractions for a relaxing vacation Odessa, Florida, offers a tranquil escape for travellers seeking spa hotels with access to rejuvenating experiences. Begin your day at the picturesque Lake Elda, where you can enjoy a peaceful morning walk or a family-friendly picnic amidst the scenic surroundings. For those looking to unwind, the nearby Serenity Spa provides a range of treatments, from massages to facials, ensuring you leave feeling refreshed. Explore the lush trails of the J.B. Starkey Wilderness Park, perfect for both hiking and cycling, where you can connect with nature and breathe in the fresh air. After a day of adventure, indulge in gourmet dining at local restaurants like the popular Tarpon Springs Sponge Docks, offering fresh seafood and a taste of authentic Florida. Consider staying in the charming, boutique-style hotels in the area that not only provide luxurious amenities but also personalised service to enhance your experience. With the perfect blend of relaxation and exploration, Odessa invites you to create unforgettable memories. ## Top Odessa Hotel Reviews ![Wyndham Grand Clearwater Beach](https://images.trvl-media.com/lodging/16000000/15920000/15914400/15914352/3e998290_y.jpg) ### Wyndham Grand Clearwater Beach 10/10 Excellent "Everything was great. I didn’t like the high price for parking. I feel like it should be less. " [](https://expedia.ca/St-Petersburg-Clearwater-Hotels-Wyndham-Grand-Clearwater-Beach.h15914352.Hotel-Information) ![Hyatt Regency Clearwater Beach Resort & Spa](https://images.trvl-media.com/lodging/3000000/2710000/2703500/2703419/c3ff81f1_y.jpg) ### Hyatt Regency Clearwater Beach Resort & Spa 10/10 Excellent "Room and bathroom was pre outdated but clean, bed is really comfortable and bed sheet is very fresh . Pool is very nice but hot tub is outdated. Staffs are amazing very kind .I would come back. Breakfast is a bit disappointed than I expected." [](https://expedia.ca/St-Petersburg-Clearwater-Hotels-Hyatt-Regency-Clearwater-Beach-Resort-Spa.h2703419.Hotel-Information) ![Hilton Clearwater Beach Resort & Spa](https://images.trvl-media.com/lodging/1000000/30000/28100/28023/da46d3f6_y.jpg) ### Hilton Clearwater Beach Resort & Spa 10/10 Excellent "I will definitely be back❤️ it’s centered perfectly for the beach, night life, sport views and food amenities l" [](https://expedia.ca/St-Petersburg-Clearwater-Hotels-Hilton-Clearwater-Beach-Resort-Spa.h28023.Hotel-Information) ![Seminole Hard Rock Hotel & Casino Tampa](https://images.trvl-media.com/lodging/2000000/1050000/1044200/1044188/6efee43c_y.jpg) ### Seminole Hard Rock Hotel & Casino Tampa 10/10 Excellent "Nice spot" [](https://expedia.ca/Tampa-Hotels-Seminole-Hard-Rock-Hotel-Casino-Tampa.h1044188.Hotel-Information) ## Frequently asked questions ### How much does a spa hotel in Odessa cost? ### Is it cheaper to book a spa hotel in Odessa with flights as part of a package deal? ### Are there any unique spa experiences available in Odessa? > Skin NV Odessa Med Spa focuses on cutting-edge aesthetic and skincare treatments, including laser hair removal, IPL laser, Botox, dermal fillers, microneedling, CoolPeel laser, and unique Salmon DNA facials. This med spa combines advanced technology with expert professionals for non-surgical cosmetic rejuvenation. > > > LivingYoung Centre provides holistic and anti-aging wellness therapies that concentrate on mental, physical, and spiritual health. Their services feature non-invasive treatments and cosmetic injectables designed to reverse signs of ageing and promote vitality. > > > Happy Nails & Spa is a local nail salon offering professional nail care services such as liquid gel nails, SNS dipping powder, manicures, pedicures, and waxing, all within a relaxing setting. It prioritises up-to-date nail technology and trends for a unique and affordable experience. > > > Touch Nail Spa III features natural organic nail and beauty services tailored to individual wellness needs, blending beauty with health-focused treatments. > > > While Odessa provides these specialised and modern spa and wellness services, for a more historic and mineral spring-based spa experience, nearby Tampa has the Safety Harbor Resort & Spa, which is Florida's only natural mineral springs spa, known for its restorative mineral water treatments and an extensive wellness environment. ### How can I save on a spa hotel in Odessa with Expedia? ### Can I cancel my spa hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - More ways to book - [Adults Only Resorts & in Central Florida ](https://www.expedia.ca/Central-Florida-Hotels-Adults-Only-Resorts.0-0-d6048177-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Central Florida ](https://www.expedia.ca/Central-Florida-Hotels-Beach-Hotel.0-0-d6048177-tBeachHotel.Travel-Guide-Filter-Hotels) - 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