Name: 21C Museum Hotel St Louis
Price range: CA $222
Rating: 9

Your Northwoods Vacation

With plenty of highlights as well as hidden gems, this city is best explored with a Northwoods vacation package. Check out places to stay in Downtown St. Louis, which is great for festivals, bars and pubs and dining. A trip to Northwoods is an ideal opportunity to do a bit of sightseeing. Make sure you visit renowned attractions like St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis. Expedia has what you need to escape your daily routine. Tailor your vacation to Northwoods to suit your travel style, whatever that may look like.

Top Northwoods Vacation Deals

Price found within the past 48 hours. Click for updated prices.

Comfort Suites Rolla

CA $1,166

per person

May 23 - May 30

found 23 hours ago

Roundtrip flight included

Toronto (YYZ) to St. Louis (STL)

8.6/10 Excellent! (1,001 reviews)

The breakfast was plenty and satisfactory. The hotel was old, but clean and the rooms were huge, again old but clean

Reviewed on Mar 30, 2026

Quality Inn Rolla

CA $1,419

per person

May 23 - May 30

found 22 hours ago

Roundtrip flight included

Toronto (YYZ) to St. Louis (STL)

8/10 Very Good! (371 reviews)

The room was warm and clean. I mention some things and they were going to fix the problems.Very nice staff member, but the nice warm room was the top of everything. After driving with the cold weather for 7 hours,that room was the best thing anyone could imagine. Thanks to the staff.

Reviewed on Feb 24, 2026

Holiday Inn Express Hotel & Suites Rolla - U of Missouri S&T by IHG

CA $1,341

per person

May 23 - May 30

found 23 hours ago

Roundtrip flight included

Toronto (YYZ) to St. Louis (STL)

8.8/10 Excellent! (904 reviews)

We enjoyed out stay here. The rooms were clean and the bed was comfortable. It was close to a restaurant which also had very good food. We will stay here again whenever we return.

Reviewed on Mar 23, 2026

Hermann Grain Bins BNB

CA $3,382

per person

May 23 - May 30

found 22 hours ago

Roundtrip flight included

Toronto (YYZ) to St. Louis (STL)

2/10 (1 review)

Hampton Inn Rolla

CA $2,173

per person

May 23 - May 30

found 22 hours ago

Roundtrip flight included

Toronto (YYZ) to St. Louis (STL)

9.2/10 Wonderful! (476 reviews)

Didn’t get to try the breakfast, but the staff were nice and the room was great.

Reviewed on Mar 29, 2026

Ready to book your vacation to Northwoods?

Choose your dates

Northwoods Hotel Deals

Pear Tree Inn St. Louis Near Union Station

2211 Market Street St. Louis MO

Fully refundableReserve now, pay when you stay

CA $158

CA $184 total

Apr 16 - Apr 17

includes taxes & fees

8.8/10 Excellent! (1,922 reviews)

There was a big event in town so was very crowded long line for breakfast but what we have was good didnt get to go to the pool or hot tub thier were too many people in there

Reviewed on Apr 5, 2026

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO

CA $234

CA $274 total

Apr 19 - Apr 20

includes taxes & fees

9.4/10 Exceptional! (3,354 reviews)

Clean roon

Reviewed on Apr 4, 2026

21C Museum Hotel St Louis

1528 Locust street St. Louis MO

Fully refundableReserve now, pay when you stay

CA $222

CA $266 total

Apr 6 - Apr 7

includes taxes & fees

9/10 Wonderful! (1,723 reviews)

This is a unique property. Pool and health club are incredible.

Reviewed on Apr 5, 2026

See all 1,878 properties in Northwoods

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.