Title: The 10 Best Hotels Near National Medical Center, Mexico City from CA $76 | Expedia.ca

[Cuauhtémoc Travel Guide](https://expedia.ca/Mexico-City-Cuauhtemoc.dx179289)[National Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-National-Medical-Center.d6266105.Car-Rental-Guide)[National Medical Center Vacations](https://expedia.ca/National-Medical-Center-Cuauhtemoc.d6266105.Vacation-Attraction)

![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)  
###  
Change your mind  
Book hotels with free cancellation
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)  
###  
Treat yourself  
Sign in to save 10% or more on thousands of hotels  
[Sign in](https://www.expedia.ca/login)
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)  
###  
Be picky  
Search almost a million properties worldwide

## Check prices for these dates

Tonight

[Apr 6 - Apr 7](https://www.expedia.ca/Hotel-Search?regionId=6266105&startDate=2026-04-06&endDate=2026-04-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Apr 7 - Apr 8](https://www.expedia.ca/Hotel-Search?regionId=6266105&startDate=2026-04-07&endDate=2026-04-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6266105&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=6266105&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for National Medical Center (Siglo XXI) hotels

![Deluxe Double Room](https://images.trvl-media.com/lodging/84000000/84000000/83993200/83993143/710ee081.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Double Room](https://images.trvl-media.com/lodging/84000000/84000000/83993200/83993143/c3869e51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/84000000/84000000/83993200/83993143/0939689a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Double Room](https://images.trvl-media.com/lodging/84000000/84000000/83993200/83993143/b8084e8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### NaNa Vida CDMX

[](https://www.expedia.ca/Mexico-City-Hotels-NaNa-Vida-Hotel-CDMX.h83993143.Hotel-Information)

Roma Norte, 0.9 km from National Medical Center (Siglo XXI)

9.8/10

Exceptional

(428 reviews)

"This was an absolute gem, such friendly staff, beautiful accommodations, and great location! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lisa

CA $138

CA $165 total

includes taxes & fees

Apr 9 - Apr 10

[](https://www.expedia.ca/Mexico-City-Hotels-NaNa-Vida-Hotel-CDMX.h83993143.Hotel-Information)

![Premium Apartment, Non Smoking, City View | Living area](https://images.trvl-media.com/lodging/104000000/103310000/103307200/103307165/627336f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Apartment, Non Smoking, City View | Living area](https://images.trvl-media.com/lodging/104000000/103310000/103307200/103307165/11c9eab0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, Non Smoking, City View](https://images.trvl-media.com/lodging/104000000/103310000/103307200/103307165/88edf63a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Apartment, Non Smoking, City View | Living area](https://images.trvl-media.com/lodging/104000000/103310000/103307200/103307165/6ea2d169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Serenos

[](https://www.expedia.ca/Mexico-City-Hotels-Casa-Serenos.h103307165.Hotel-Information)

Roma Sur, 1.3 km from National Medical Center (Siglo XXI)

10/10

Exceptional

(10 reviews)

"Beautiful hotel in great location..kind and attentive staff. Felt very safe. Beautiful rooms!!"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Amrita

CA $202

CA $241 total

includes taxes & fees

Apr 18 - Apr 19

[](https://www.expedia.ca/Mexico-City-Hotels-Casa-Serenos.h103307165.Hotel-Information)

![Hallway](https://images.trvl-media.com/lodging/106000000/105990000/105981300/105981258/80c1e0cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Room](https://images.trvl-media.com/lodging/106000000/105990000/105981300/105981258/4ce62815.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/106000000/105990000/105981300/105981258/5a93de12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/106000000/105990000/105981300/105981258/ac867fe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Escala Colonia Roma

[](https://www.expedia.ca/Mexico-City-Hotels-Hotel-Cervantes.h105981258.Hotel-Information)

Roma Norte, 0.6 km from National Medical Center (Siglo XXI)

9.2/10

Wonderful

(415 reviews)

"Great location, clean room, friendly staff. Definitely a no frills type of stay but would stay again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maura

CA $62

CA $76 total

includes taxes & fees

Apr 9 - Apr 10

[](https://www.expedia.ca/Mexico-City-Hotels-Hotel-Cervantes.h105981258.Hotel-Information)

![Interior detail](https://images.trvl-media.com/lodging/111000000/110930000/110923600/110923528/c00a3bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, in-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/111000000/110930000/110923600/110923528/9316d84b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/111000000/110930000/110923600/110923528/afec6188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/111000000/110930000/110923600/110923528/ee680827.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lasai Casa Tonala

[](https://www.expedia.ca/Mexico-City-Hotels-Lasai-Casa-Tonala.h110923528.Hotel-Information)

Roma Norte, 1 km from National Medical Center (Siglo XXI)

9.6/10

Exceptional

(27 reviews)

"It's a great place to stay and it's affordable. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Vismaya

CA $91

CA $155 total

includes taxes & fees

Apr 13 - Apr 14

[](https://www.expedia.ca/Mexico-City-Hotels-Lasai-Casa-Tonala.h110923528.Hotel-Information)

![Penthouse with a Private Terrace | Terrace/patio](https://images.trvl-media.com/lodging/97000000/96500000/96490800/96490754/b4fd9404.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Penthouse with a Private Terrace | Private kitchen](https://images.trvl-media.com/lodging/97000000/96500000/96490800/96490754/cc15c546.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Penthouse with a Private Terrace | Living area](https://images.trvl-media.com/lodging/97000000/96500000/96490800/96490754/57eba2b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/97000000/96500000/96490800/96490754/53f46e94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ULIV Roma Norte

[](https://www.expedia.ca/Mexico-City-Hotels-ULIV-Roma-Norte.h96490754.Hotel-Information)

Roma Norte, 0.8 km from National Medical Center (Siglo XXI)

9.4/10

Exceptional

(373 reviews)

"Staff was super helpful. Great stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Wilhelm

CA $125

CA $149 total

includes taxes & fees

Apr 7 - Apr 8

[](https://www.expedia.ca/Mexico-City-Hotels-ULIV-Roma-Norte.h96490754.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95330000/95322400/95322391/aa7bae7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Studio Suite](https://images.trvl-media.com/lodging/96000000/95330000/95322400/95322391/f349d35f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Room](https://images.trvl-media.com/lodging/96000000/95330000/95322400/95322391/74d04a96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Studio Suite](https://images.trvl-media.com/lodging/96000000/95330000/95322400/95322391/01b1fa16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Seis Siete

[](https://www.expedia.ca/Mexico-City-Hotels-Casa-Seis-Siete.h95322391.Hotel-Information)

Roma Norte, 1.3 km from National Medical Center (Siglo XXI)

10/10

Exceptional

(58 reviews)

"Beautiful property, amazing location, very friendly and helpful staff. Highly recommend!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cassio

CA $466

CA $557 total

includes taxes & fees

Apr 26 - Apr 27

[](https://www.expedia.ca/Mexico-City-Hotels-Casa-Seis-Siete.h95322391.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/10000000/9070000/9061700/9061610/12c19126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9070000/9061700/9061610/179170cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/10000000/9070000/9061700/9061610/a99a15aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/10000000/9070000/9061700/9061610/2e473752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Marbella

[](https://www.expedia.ca/Mexico-City-Hotels-Hotel-Marbella.h9061610.Hotel-Information)

Roma Norte, 0.7 km from National Medical Center (Siglo XXI)

9.0/10

Wonderful

(1,001 reviews)

"Nice staff, clean room and good location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ana

CA $104

CA $128 total

includes taxes & fees

Apr 7 - Apr 8

[](https://www.expedia.ca/Mexico-City-Hotels-Hotel-Marbella.h9061610.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/109000000/108760000/108751700/108751638/ef44681e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 1 Bedroom, Balcony | Living area](https://images.trvl-media.com/lodging/109000000/108760000/108751700/108751638/f405ba56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Loft, 1 Bedroom](https://images.trvl-media.com/lodging/109000000/108760000/108751700/108751638/ad4cb581.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/109000000/108760000/108751700/108751638/19eafbbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cuadra 134 Residencial Condesa

[](https://www.expedia.ca/Mexico-City-Hotels-Cuadra-134-Residencial.h108751638.Hotel-Information)

Roma Norte, 1 km from National Medical Center (Siglo XXI)

9.4/10

Exceptional

(326 reviews)

"Nice are to stay at will stay again "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Adan

CA $161

CA $196 total

includes taxes & fees

May 3 - May 4

[](https://www.expedia.ca/Mexico-City-Hotels-Cuadra-134-Residencial.h108751638.Hotel-Information)

![Luxury Suite, 1 King Bed, City View](https://images.trvl-media.com/lodging/92000000/91380000/91374000/91373978/858366d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Studio Suite | Living area](https://images.trvl-media.com/lodging/92000000/91380000/91374000/91373978/8431051c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/92000000/91380000/91374000/91373978/eabbff75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/92000000/91380000/91374000/91373978/eb28b4a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Colima 71 Casa de Arte Hotel

[](https://www.expedia.ca/Mexico-City-Hotels-Colima-71-Art-Community-Hotel.h91373978.Hotel-Information)

Roma Norte, 1.4 km from National Medical Center (Siglo XXI)

10/10

Exceptional

(46 reviews)

"Perfect Roma Norte location, everything is close and in walking distance, the hotel is so pleasant, smiling faces all around, cute breakfast, very friendly staff, we have nothing but good things to say and great memories to cherish. Will we be back? You bet we will!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amir

CA $734

CA $948 total

includes taxes & fees

Apr 12 - Apr 13

[](https://www.expedia.ca/Mexico-City-Hotels-Colima-71-Art-Community-Hotel.h91373978.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/97000000/96740000/96730700/96730682/a3d95e1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![43-inch Smart TV with digital channels, books](https://images.trvl-media.com/lodging/97000000/96740000/96730700/96730682/5aef643d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/97000000/96740000/96730700/96730682/89785662.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Room | Bathroom](https://images.trvl-media.com/lodging/97000000/96740000/96730700/96730682/f022b867.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Izeba

[](https://www.expedia.ca/Mexico-City-Hotels-Casa-Izeba.h96730682.Hotel-Information)

Roma Norte, 1.5 km from National Medical Center (Siglo XXI)

10/10

Exceptional

(86 reviews)

"This place was amazing! Really made the trip! The staff is very attentive. The hotel is beautiful and elegant. Highly recommend. Well worth the splurge. The complimentary pastries from panadería Rossetta were delicious!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Monica

CA $614

CA $734 total

includes taxes & fees

Apr 12 - Apr 13

[](https://www.expedia.ca/Mexico-City-Hotels-Casa-Izeba.h96730682.Hotel-Information)

![Loft, Terrace](https://images.trvl-media.com/lodging/20000000/19750000/19741900/19741862/57fb78d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Loft, Terrace | Private kitchen](https://images.trvl-media.com/lodging/20000000/19750000/19741900/19741862/6762895c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch Smart TV with cable channels, TV](https://images.trvl-media.com/lodging/20000000/19750000/19741900/19741862/e121e153.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, coffee/tea maker](https://images.trvl-media.com/lodging/20000000/19750000/19741900/19741862/5f7b55ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### OM686 Urban Lofts Short-Long Stays

[](https://www.expedia.ca/Mexico-City-Hotels-OM-686-Urban-Lofts.h19741862.Hotel-Information)

1 km from National Medical Center (Siglo XXI)

9.4/10

Exceptional

(258 reviews)

"Cute place, the staff were amazing. Loved the beautiful outside sitting area."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Rebecca

CA $82

CA $98 total

includes taxes & fees

May 3 - May 4

[](https://www.expedia.ca/Mexico-City-Hotels-OM-686-Urban-Lofts.h19741862.Hotel-Information)

![Smart TV, streaming services](https://images.trvl-media.com/lodging/102000000/101340000/101333500/101333489/3aecdb2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Suite, 1 Queen Bed with Sofa bed](https://images.trvl-media.com/lodging/102000000/101340000/101333500/101333489/3cf3a4c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/102000000/101340000/101333500/101333489/90cb7172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, coffee/tea maker, blender](https://images.trvl-media.com/lodging/102000000/101340000/101333500/101333489/47728f56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tanat Art Hotel

[](https://www.expedia.ca/Mexico-City-Hotels-Tanat.h101333489.Hotel-Information)

Roma Sur, 1.4 km from National Medical Center (Siglo XXI)

9.6/10

Exceptional

(146 reviews)

"This is a terrific location, a bit off the beaten path, but close to Condessa and Roma Norte. The staff were very courteous. The room is really a small apartment, and one could stay here comfortably and cook if needed."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Kyra Antoinette

CA $98

CA $146 total

includes taxes & fees

Apr 7 - Apr 8

[](https://www.expedia.ca/Mexico-City-Hotels-Tanat.h101333489.Hotel-Information)

![Deluxe Room](https://images.trvl-media.com/lodging/113000000/112880000/112870900/112870886/52f311f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Room | Bathroom](https://images.trvl-media.com/lodging/113000000/112880000/112870900/112870886/0ea875fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room](https://images.trvl-media.com/lodging/113000000/112880000/112870900/112870886/734249c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Suite, Balcony, City View | Terrace/patio](https://images.trvl-media.com/lodging/113000000/112880000/112870900/112870886/b7bcdd80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Tenue

[](https://www.expedia.ca/Mexico-City-Hotels-Casa-Tenue.h112870886.Hotel-Information)

Roma Norte, 1.6 km from National Medical Center (Siglo XXI)

10/10

Exceptional

(16 reviews)

"Cutest place, excellent location and phenomenal service! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nehal

CA $428

CA $511 total

includes taxes & fees

Apr 9 - Apr 10

[](https://www.expedia.ca/Mexico-City-Hotels-Casa-Tenue.h112870886.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/118000000/117740000/117737400/117737383/6a66151a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/118000000/117740000/117737400/117737383/dc585a1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/118000000/117740000/117737400/117737383/40b9bcc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Apartment](https://images.trvl-media.com/lodging/118000000/117740000/117737400/117737383/w2518h1620x0y0-7871811a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Kukun Tonalá 121 Roma 

[](https://www.expedia.ca/Mexico-City-Hotels-Kukun-Roma.h117737383.Hotel-Information)

Roma Norte, 1.3 km from National Medical Center (Siglo XXI)

9.4/10

Exceptional

(58 reviews)

"Wonderful stay here. Rooms were spacious for two adults and clean. Location is excellent. As others have noted, can be loud at night especially if the room is facing the street, so using ear plugs was necessary for us. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Natasha

CA $150

CA $179 total

includes taxes & fees

Apr 7 - Apr 8

[](https://www.expedia.ca/Mexico-City-Hotels-Kukun-Roma.h117737383.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/126000000/125340000/125340000/125339942/26c35b07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/126000000/125340000/125340000/125339942/2da624a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Design Studio Suite, 1 King Bed, City View](https://images.trvl-media.com/lodging/126000000/125340000/125340000/125339942/6ffc708d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, 1 King Bed | Living area](https://images.trvl-media.com/lodging/126000000/125340000/125340000/125339942/acb38222.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Maximo Mexico Hotel

[](https://www.expedia.ca/Mexico-City-Hotels-Maximo-Roma.h125339942.Hotel-Information)

Roma Sur, 1.3 km from National Medical Center (Siglo XXI)

9.4/10

Exceptional

(8 reviews)

"The Hotel is not ready at 100% , the need experience and finishing all installation, Also elevator was stocked not good experience."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Yadira

CA $189

CA $226 total

includes taxes & fees

Apr 18 - Apr 19

[](https://www.expedia.ca/Mexico-City-Hotels-Maximo-Roma.h125339942.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/90000000/89010000/89003100/89003031/02f353d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Room](https://images.trvl-media.com/lodging/90000000/89010000/89003100/89003031/436ea766.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/90000000/89010000/89003100/89003031/029ba232.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily cooked-to-order breakfast (USD 13 per person)](https://images.trvl-media.com/lodging/90000000/89010000/89003100/89003031/1c46fd66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Roso Guest House

[](https://www.expedia.ca/Mexico-City-Hotels-Roso-Guest-House.h89003031.Hotel-Information)

Roma Norte, 1.3 km from National Medical Center (Siglo XXI)

9.6/10

Exceptional

(63 reviews)

"Room spotless, very friendly staff. Loved the breakfast area patio. Glad we had a/c. Perfect location in Roma Norte. Great place to stay, highly recommend staying here. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Irene

CA $377

CA $451 total

includes taxes & fees

Apr 22 - Apr 23

[](https://www.expedia.ca/Mexico-City-Hotels-Roso-Guest-House.h89003031.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/105000000/104150000/104143500/104143489/89ca76d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/105000000/104150000/104143500/104143489/5445a46e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/105000000/104150000/104143500/104143489/2772dacd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment, 2 Bedrooms, Non Smoking, Kitchen](https://images.trvl-media.com/lodging/105000000/104150000/104143500/104143489/308f1486.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TONALA by Mr. W

[](https://www.expedia.ca/Mexico-City-Hotels-TONALA-By-Mr-W.h104143489.Hotel-Information)

Roma Norte, 1.2 km from National Medical Center (Siglo XXI)

9.4/10

Exceptional

(35 reviews)

"We were greeted by Paulina. She was so helpful and had great recommendations. Rooms were clean and each room had its own bathroom. Great location. We walked to amazing restaurants and shops. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

sherrie

CA $155

CA $185 total

includes taxes & fees

Apr 8 - Apr 9

[](https://www.expedia.ca/Mexico-City-Hotels-TONALA-By-Mr-W.h104143489.Hotel-Information)

![Terrace Suite](https://images.trvl-media.com/lodging/77000000/76260000/76254900/76254803/f2bc2b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/77000000/76260000/76254900/76254803/111222e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/77000000/76260000/76254900/76254803/743672f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Park View Balcony Suite](https://images.trvl-media.com/lodging/77000000/76260000/76254900/76254803/090e7a60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### HOTEL LUCA

[](https://www.expedia.ca/Mexico-City-Hotels-HOTEL-LUCA.h76254803.Hotel-Information)

Roma Norte, 1.1 km from National Medical Center (Siglo XXI)

9.2/10

Wonderful

(358 reviews)

"Love the location and the style of this hotel, nice small friendly cosy."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lethia

CA $336

CA $402 total

includes taxes & fees

Apr 7 - Apr 8

[](https://www.expedia.ca/Mexico-City-Hotels-HOTEL-LUCA.h76254803.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355956/4263d2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Ocre | Bathroom](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355956/1334a356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Alba | Living area](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355956/779a4f68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Alba | Living area](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355956/60b56e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Maison Celeste

[](https://www.expedia.ca/Mexico-City-Hotels-Maison-Celeste.h95355956.Hotel-Information)

Roma Norte, 1.1 km from National Medical Center (Siglo XXI)

9.4/10

Exceptional

(28 reviews)

"Great location! Welcoming staff. We really enjoyed our visit. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

William

CA $436

CA $521 total

includes taxes & fees

Apr 13 - Apr 14

[](https://www.expedia.ca/Mexico-City-Hotels-Maison-Celeste.h95355956.Hotel-Information)

![Grand Apartment | Living area](https://images.trvl-media.com/lodging/105000000/104150000/104143200/104143113/14218395.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Grand Apartment](https://images.trvl-media.com/lodging/105000000/104150000/104143200/104143113/ac4ff660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Elite Apartment](https://images.trvl-media.com/lodging/105000000/104150000/104143200/104143113/b7714bab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment | Living area](https://images.trvl-media.com/lodging/105000000/104150000/104143200/104143113/bc1c1d7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SAN LUIS POTOSI by Mr. W

[](https://www.expedia.ca/Mexico-City-Hotels-SAN-LUIS-POTOSI-By-Mr-W.h104143113.Hotel-Information)

Roma Norte, 0.8 km from National Medical Center (Siglo XXI)

9.0/10

Wonderful

(7 reviews)

"Excellent, highly recommend, very friendly and communicative staff and great location. Will be back!"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

David

CA $115

CA $160 total

includes taxes & fees

Apr 7 - Apr 8

[](https://www.expedia.ca/Mexico-City-Hotels-SAN-LUIS-POTOSI-By-Mr-W.h104143113.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-20&endDate=2026-04-21&regionId=6266105&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Compare popular hotels close to National Medical Center (Siglo XXI)

| Property                                                                                                                                                                                                    | Star rating       | Guest rating              | Breakfast included | Pool | Spa | Pet-friendly | WiFi included |  |
| ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- |  |
| ![Deluxe Double Room](https://images.trvl-media.com/lodging/84000000/84000000/83993200/83993143/710ee081.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)NaNa Vida CDMX                                         | 4.0 star property | 9.8Exceptional428 reviews | View               |      |     |              |               |  |
| ![Premium Apartment, Non Smoking, City View \| Living area](https://images.trvl-media.com/lodging/104000000/103310000/103307200/103307165/627336f1.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Casa Serenos | 3.0 star property | 10.0Exceptional10 reviews | View               |      |     |              |               |  |
| ![Hallway](https://images.trvl-media.com/lodging/106000000/105990000/105981300/105981258/80c1e0cd.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel Escala Colonia Roma                                     | 2.0 star property | 9.2Wonderful415 reviews   | View               |      |     |              |               |  |
| ![Interior detail](https://images.trvl-media.com/lodging/111000000/110930000/110923600/110923528/c00a3bed.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Lasai Casa Tonala                                     | 3.5 star property | 9.6Exceptional27 reviews  | View               |      |     |              |               |  |
| ![Penthouse with a Private Terrace \| Terrace/patio](https://images.trvl-media.com/lodging/97000000/96500000/96490800/96490754/b4fd9404.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)ULIV Roma Norte         | 4.0 star property | 9.4Exceptional373 reviews | View               |      |     |              |               |  |

## Top National Medical Center Hotel Reviews

![ULIV Mexico City](https://images.trvl-media.com/lodging/111000000/110130000/110122500/110122446/54f1273a_y.jpg)

### ULIV Mexico City

10/10 Excellent

"Easy check-in, clean and beautiful views from rooftop "

[](https://expedia.ca/Mexico-City-Hotels-ULIV-Mexico-City.h110122446.Hotel-Information)

![Cuadra 134 Residencial Condesa](https://images.trvl-media.com/lodging/109000000/108760000/108751700/108751638/ef44681e_y.jpg)

### Cuadra 134 Residencial Condesa

10/10 Excellent

"Clean apartment style room with everything we needed for a short stay. Comfortable bed and easy to navigate the area from this location "

[](https://expedia.ca/Mexico-City-Hotels-Cuadra-134-Residencial.h108751638.Hotel-Information)

![Fiesta Americana Reforma](https://images.trvl-media.com/lodging/1000000/10000/4400/4366/934444df_y.jpg)

### Fiesta Americana Reforma

10/10 Excellent

"The staff was very nice. The hotel was very generous and offered us a nice breakfast and a snack in the afternoon. "

[](https://expedia.ca/Mexico-City-Hotels-Fiesta-Americana-Reforma.h4366.Hotel-Information)

![Hotel Embassy](https://images.trvl-media.com/lodging/36000000/35200000/35191700/35191695/fe30d475_y.jpg)

### Hotel Embassy

2/10 Terrible

"We arrived at 5:00 PM to check in and were directed by reception to Room 302, only to be told by a cleaner that the room wasn’t ready and that we would need to wait. Check in begins at 3:00 PM. Eventually, reception assigned us a different room, but when we got there, the door was already open, which felt unusual and concerning. Unfortunately, the condition of the room was unacceptable: The bed frame was broken at both ends, with pieces lying on the floor. There were puddles of water next to the bed, along with long hairs on the floor and even on the shower wall. The sink counter also had a noticeable hole in it. To make matters worse, the room was advertised on Expedia as having air conditioning, which was a key reason we booked it...but it did not work. No remote or function to turn it on. We had booked this room simply to store our luggage, rest, and take a shower before our flight. However, given the state of the room and bathroom, we didn’t feel comfortable doing any of those things. We ended up leaving early and spending our time elsewhere until our flight. Overall, a very disappointing experience. Would not recommend"

[](https://expedia.ca/Mexico-City-Hotels-Hotel-Embassy.h35191695.Hotel-Information)

![Galeria Plaza Reforma](https://images.trvl-media.com/lodging/1000000/590000/582800/582712/3c7cdb37_y.jpg)

### Galeria Plaza Reforma

2/10 Terrible

"No good "

[](https://expedia.ca/Mexico-City-Hotels-Galeria-Plaza-Reforma.h582712.Hotel-Information)

![Ignacia Guest House](https://images.trvl-media.com/lodging/18000000/17810000/17809100/17809084/51291bbf_y.jpg)

### Ignacia Guest House

10/10 Excellent

"What an unusual treat this was! Very artsy and fun place to stay. The service was outstanding along with breakfast and happy hour! My only complaint would be our very tiny room."

[](https://expedia.ca/Mexico-City-Hotels-Ignacia-Guest-House.h17809084.Hotel-Information)

![ULIV Cibeles](https://images.trvl-media.com/lodging/103000000/102370000/102366400/102366308/e7d63458_y.jpg)

### ULIV Cibeles

10/10 Excellent

"Beautiful property in an excellent location; you can walk anywhere! The room had a spectacular view of the city and had a fully stocked kitchen. The ameneties included a beautiful terrace with room to relax, a large gym with real equipment, and a game room for the family. Highly recommend!"

[](https://expedia.ca/Mexico-City-Hotels-ULIV-Cibeles.h102366308.Hotel-Information)

![HOTEL LUCA](https://images.trvl-media.com/lodging/77000000/76260000/76254900/76254803/f2bc2b19_y.jpg)

### HOTEL LUCA

10/10 Excellent

"Great location and really clean property!"

[](https://expedia.ca/Mexico-City-Hotels-HOTEL-LUCA.h76254803.Hotel-Information)

![Colony Residences & Suites](https://images.trvl-media.com/lodging/118000000/117730000/117723900/117723862/93cd0d66_y.jpg)

### Colony Residences & Suites

10/10 Excellent

"The room seemed clean but my husband told me he had found some hairs on his bed sheets. The location was excellent, very close to a lot of attractions. The price was reasonable for what we got. The staff was amazing, very helpful. Would definitely stay there again. "

[](https://expedia.ca/Mexico-City-Hotels-HIVE-ROMA-BY-G-HOTELS.h117723862.Hotel-Information)

## Hotels near other National Medical Center attractions

### Abelardo L. Rodriguez Murals

Enjoy an outing to Abelardo L. Rodriguez Murals during your stay in Mexico City. Experience the great live music and fascinating museums in this culturally rich area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532630551)

### Parque Delta

During your visit to Mexico City, you can find the perfect gifts to bring home at Parque Delta. Experience the great live music and fascinating museums in this culturally rich area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6199448)

### Medellín Market

You can do some window-shopping at Medellín Market during your visit to Mexico City. Discover the charming cafes and fascinating museums in this vibrant area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=797057513001803776)

### Antique Toy Museum

You can browse the exhibits at Antique Toy Museum, a museum with a storied past, during your trip to Mexico City. Visit the stunning cathedral and shops in this vibrant area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532630555)

### Casa Lamm Cultural Center

Enjoy an outing to Casa Lamm Cultural Center during your stay in Mexico City. Discover the great live music and notable monuments in this culturally rich area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=889815122372354048)

### Multum Ha Cenote

Learn about the local history of Mexico City with a stop at Multum Ha Cenote. Discover the great live music and notable monuments in this vibrant area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621558114865)

### Plaza Insurgentes Shopping Center

During your trip to Mexico City, you can enjoy retail therapy at Plaza Insurgentes Shopping Center. Experience the acclaimed art scene and great live music in this culturally rich area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621575904539)

### Plaza Río de Janeiro

Find out about the history of Mexico City when you take a trip to Plaza Río de Janeiro. Visit the shops and notable monuments in this culturally rich area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=889814907963711488)

## Frequently asked questions

### What's the area like around National Medical Center (Siglo XXI)?

### What's the best place to stay close to National Medical Center (Siglo XXI)?

### How many hotels will I be able to find close to National Medical Center (Siglo XXI)?

### If I need to cancel the hotel reservation for my stay near National Medical Center (Siglo XXI), will I receive a refund?

### What can I see and do near National Medical Center (Siglo XXI)?

### How can I get to National Medical Center (Siglo XXI)?