Title: Book the Best Mexico SPA Resorts from CA $112 - Spa Hotels in Mexico, MO | Expedia.ca [Mexico Travel Guide](https://expedia.ca/Mexico.dx8832)[Hotels in Mexico](https://expedia.ca/Mexico-Hotels.d8832.Travel-Guide-Hotels)[Vacation Rentals in Mexico](https://expedia.ca/Mexico-Vacation-Rentals.d8832.Travel-Guide-VacationRentals)[Flights to Mexico](https://expedia.ca/Cheap-Flights-To-Mexico.d8832.Travel-Guide-Flights)[Mexico Car Rentals](https://expedia.ca/Car-Rentals-In-Mexico.d8832.Car-Rental-Guide)[Mexico Vacation Packages](https://expedia.ca/Mexico.d8832.Destination-Travel-Guides) ![An old historic schoolhouse in Mexico, Missouri](https://images.trvl-media.com/place/8832/e1361911-161d-4582-a125-73ebc2a9a18c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Mexico, MO from CA $112 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mexico Spa Hotels Tonight [Dec 21 - Dec 22](https://www.expedia.ca/Hotel-Search?regionId=8832&startDate=2025-12-21&endDate=2025-12-22&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 22 - Dec 23](https://www.expedia.ca/Hotel-Search?regionId=8832&startDate=2025-12-22&endDate=2025-12-23&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=8832&startDate=2025-12-26&endDate=2025-12-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=8832&startDate=2026-01-02&endDate=2026-01-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in Mexico ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/67500/67443/w3837h2557x3y3-b93b14e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Refrigerator](https://images.trvl-media.com/lodging/1000000/70000/67500/67443/f44b6913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/67500/67443/7cf51208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/70000/67500/67443/b544036f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Teal Lake Inn [](https://www.expedia.ca/Columbia-Hotels-Best-Western-Teal-Lake-Inn.h67443.Hotel-Information) Mexico 8.4/10 Very good (485) "Very clean, well ran hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie CA $130 CA $145 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Columbia-Hotels-Best-Western-Teal-Lake-Inn.h67443.Hotel-Information) ![Iron/ironing board, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/161b0a31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/fcdb510e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/d033dcd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/4ac397d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Mexico [](https://www.expedia.ca/Columbia-Hotels-Days-Inn-By-Wyndham-Mexico.h151247.Hotel-Information) Mexico 7.0/10 Good (296) "Comfortable bed... Didn't like stool loose on base." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marvin CA $106 CA $118 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Columbia-Hotels-Days-Inn-By-Wyndham-Mexico.h151247.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107120000/107112700/107112670/9e78173a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107120000/107112700/107112670/9ec2663d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, DVD player, foosball](https://images.trvl-media.com/lodging/108000000/107120000/107112700/107112670/3924473b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107120000/107112700/107112670/c037918f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rustic 2-bedroom cabin next to 1000+ acre Conservation area near Mark Twain Lake [](https://www.expedia.ca/Mexico-Hotels-Rustic-2-Bedroom-Cabin-Next-To-1000-Acre-Conservation-Area-Near-Mark-Twain-Lake.h107112670.Hotel-Information) Paris 8.8/10 Excellent (5) "The cabin was very clean and the Host was very nice and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) TREY CA $155 CA $328 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Mexico-Hotels-Rustic-2-Bedroom-Cabin-Next-To-1000-Acre-Conservation-Area-Near-Mark-Twain-Lake.h107112670.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/24000/23979/ecac62d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/24000/23979/804413f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/24000/23979/05dc8db5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/24000/23979/463c94ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Budget Inn Mexico MO on US 54 [](https://www.expedia.ca/Columbia-Hotels-Budget-Inn.h23979.Hotel-Information) Mexico 7.0/10 Good (110) "Great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jedrzej CA $117 CA $131 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Columbia-Hotels-Budget-Inn.h23979.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17970000/17969900/17969823/w2876h1920x0y0-0813656b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/18000000/17970000/17969900/17969823/w2876h1920x4y0-27792906.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/18000000/17970000/17969900/17969823/w2870h1920x5y0-c53bab77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17970000/17969900/17969823/w2872h1920x3y0-f170820a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Capital O Amerihost Inn and Suites Mexico Hwy 54 MO [](https://www.expedia.ca/Columbia-Hotels-Amerihost-Inn-Suites-Mexico.h17969823.Hotel-Information) Mexico 5.6/10 (384) "Staff were very friendly and accommodating. Room was very clean and comfortable!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rusty [](https://www.expedia.ca/Columbia-Hotels-Amerihost-Inn-Suites-Mexico.h17969823.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/3f71cbd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/4d96f21b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/w6000h3998x0y0-b5960fdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/83e9f93b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG [](https://www.expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Hotel-Suites-Columbia-Univ-Area-Hwy-63.h7677926.Hotel-Information) Columbia 8.8/10 Excellent (1001) "Breakfast hostess was so friendly! Room was clean & comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sue CA $137 CA $155 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Hotel-Suites-Columbia-Univ-Area-Hwy-63.h7677926.Hotel-Information) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/4000000/3490000/3483600/3483569/99c31ff5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/4000000/3490000/3483600/3483569/988f8b5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/4000000/3490000/3483600/3483569/965abaf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/4000000/3490000/3483600/3483569/f7813df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Columbia East by IHG [](https://www.expedia.ca/Columbia-Hotels-Holiday-Inn-Columbia-East.h3483569.Hotel-Information) Columbia 8.4/10 Very good (1003) "Bad place " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Kareem CA $155 CA $176 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Columbia-Hotels-Holiday-Inn-Columbia-East.h3483569.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/c8809092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/w2870h1920x0y0-23ef12fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/4cbd87ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/ebcde04c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Columbia, MO [](https://www.expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) Columbia 9.0/10 Wonderful (1714) "A repeat visit staying in this hotel. Comfortable, convenient location, good breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MaryBeth CA $108 CA $122 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1090000/1085800/1085736/e3e94e62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/2000000/1090000/1085800/1085736/91b8bb32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking | Living room](https://images.trvl-media.com/lodging/2000000/1090000/1085800/1085736/b72ac7ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1090000/1085800/1085736/aae4a850.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Fulton [](https://www.expedia.ca/Columbia-Hotels-Baymont-By-Wyndham-Fulton.h1085736.Hotel-Information) Fulton 8.2/10 Very good (971) "Room was ok...staff was friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda CA $116 CA $130 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Columbia-Hotels-Baymont-By-Wyndham-Fulton.h1085736.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/fd258818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/c428cb4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/805c2520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Columbia Inn [](https://www.expedia.ca/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) Columbia 8.8/10 Excellent (1209) "Stayed here several times and was very happy with our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reynaldo CA $99 CA $112 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-04&endDate=2026-01-05®ionId=8832&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Mexico Hotel Reviews ![Country Inn & Suites by Radisson, Columbia, MO](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/c8809092_y.jpg) ### Country Inn & Suites by Radisson, Columbia, MO 10/10 Excellent "Everything was great" [](https://expedia.ca/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) ![Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG](https://images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/8a05cd33_y.jpg) ### Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG 10/10 Excellent "Breakfast hostess was so friendly! Room was clean & comfortable." [](https://expedia.ca/Columbia-Hotels-Holiday-Inn-Express-Hotel-Suites-Columbia-Univ-Area-Hwy-63.h7677926.Hotel-Information) ![Best Western Teal Lake Inn](https://images.trvl-media.com/lodging/1000000/70000/67500/67443/w3837h2557x3y3-b93b14e5_y.jpg) ### Best Western Teal Lake Inn 10/10 Excellent "Very clean, well ran hotel" [](https://expedia.ca/Columbia-Hotels-Best-Western-Teal-Lake-Inn.h67443.Hotel-Information) ![Wingate by Wyndham - Columbia](https://images.trvl-media.com/lodging/1000000/990000/986100/986086/a16387a6_y.jpg) ### Wingate by Wyndham - Columbia 10/10 Excellent "The breakfast was very tasty and had a variety of items to choose. I especially liked the pancake maker. " [](https://expedia.ca/Columbia-Hotels-Wingate-By-Wyndham-Columbia.h986086.Hotel-Information) ![Staybridge Suites Columbia by IHG](https://images.trvl-media.com/lodging/1000000/460000/454900/454853/095bb42f_y.jpg) ### Staybridge Suites Columbia by IHG 10/10 Excellent "Staff was nice & friendly. Convenient location next to the highway. Near plenty of stores & restaurants. Our room was nice a spacious. Vanity light needs to be brighter. The people above us had a child that was running back & forth. The water in our shower was not hot enough esp during a very cold weekend. Other than that our stay was fine." [](https://expedia.ca/Columbia-Hotels-Staybridge-Suites-Columbia.h454853.Hotel-Information) ![Courtyard by Marriott Columbia Missouri](https://images.trvl-media.com/lodging/2000000/1210000/1206800/1206789/82c51b2f_y.jpg) ### Courtyard by Marriott Columbia Missouri 10/10 Excellent "Very nice! Great location close to The American Royal" [](https://expedia.ca/Columbia-Hotels-Courtyard-By-Marriott-Columbia-Missouri.h1206789.Hotel-Information) ![Days Inn by Wyndham Mexico](https://images.trvl-media.com/lodging/1000000/160000/151300/151247/d033dcd0_y.jpg) ### Days Inn by Wyndham Mexico 10/10 Excellent "Comfortable bed... Didn't like stool loose on base." 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