Mesi Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Mesi Vacation

Lock in a Mesi vacation package and get set to experience this exciting city the stress-free way. Consider staying in the neighborhood of Myli, which is great for views and hiking. If your trip to Mesi includes a little sightseeing, check out renowned attractions like Rethymnon Town Hall, Rethymnon Lighthouse and Arkadi Monastery. Check out Expedia's wide range of travel options and begin planning your dream vacation to Mesi today.

Top Mesi Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Dimargio Luxury Hotel & Spa
Lagon Life Spirit Design Villas - Adults Only
Galini Palace Resort Hotel - All Inclusive
Amirandes, A Resort to Live
Domus Renier Boutique Hotel, Member of Domus Elegance Collection

Ready to book your vacation to Mesi?

 

Choose your dates

Mesi Hotel Deals

Nautilux Rethymno by Mage Hotels

Nautilux Rethymno by Mage Hotels

5 out of 5
Australon Polemiston 23 Rethymno Crete
The price is CA $259 per night from Nov 7 to Nov 8
CA $259
CA $301 total
Nov 7 - Nov 8
includes taxes & fees
9.6/10 Exceptional! (426 reviews)
"Over all hotel is nice , Everyone working here was nice and kind . Anyhow for 5 star hotel shower enclosure is only 2 stars…. It is no door from living area to the bathroom,so it is crazy cold when you get out from the shower,and enclosure itself is ridiculously uncomfortable, Other thing -guests ..."

Reviewed on Oct 26, 2026

Nautilux Rethymno by Mage Hotels
Grecotel Marine Palace & Aqua Park

Grecotel Marine Palace & Aqua Park

4 out of 5
Panormo Mylopotamos Crete Island
The price is CA $210 per night from Nov 6 to Nov 7
CA $210
CA $244 total
Nov 6 - Nov 7
includes taxes & fees
Grecotel Marine Palace & Aqua Park
The Royal Senses Resort & Spa Crete, Curio Collection Hilton

The Royal Senses Resort & Spa Crete, Curio Collection Hilton

5 out of 5
58 Km Herakliou Mylopotamos Crete
The price is CA $365 per night from Nov 6 to Nov 7
CA $365
CA $422 total
Nov 6 - Nov 7
includes taxes & fees
The Royal Senses Resort & Spa Crete, Curio Collection Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in Mesi

Frequently asked questions

How much does a Mesi vacation package cost?
Offering excellent value package deals from CA $2,691 on Expedia, you'll be surprised at how little a vacation to Mesi costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Mesi?
January, February and November are great times to search for cheap Mesi vacation packages. Travelling in less busy months means you can usually find better prices on flights and hotels.
How many days is enough for Mesi?
We'd recommend booking a Mesi vacation for a minimum of 2 days. This gives you time to check off key attractions such as Rethymnon Cathedral and Horse Park Rethymno, and check out neighbourhoods like Perivolia and Prinedes. You might even be able to make time for one or two day trips outside of Mesi.
How to find the best Mesi package deals?
Start your search for a Mesi package deal by entering your destination and preferred travel dates under our "Packages" tab. Then select some filters, like "Property type" and "Guest rating," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the perfect Mesi package deal straight away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Mesi adventure underway.
Is it cheaper to book a Mesi vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, car rental and flight into one great-value price and enjoy significant savings. You'll usually snag a better deal than booking each component individually. And you'll still get the freedom to create a personalized Mesi vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Mesi?
Enjoy incredible bargains by booking your flights in advance with Expedia. If spontaneity is more your thing, grab one of our last-minute deals for a spur-of-the-moment Mesi adventure.
How to plan a trip to Mesi?

  1. Pick your dates: What you want to do in Mesi and your preferred season will help you decide when to go.
  2. Set a budget: Factor in expenses like flights, transportation and food when working out how much to put aside for your trip to Mesi. Then, choose a property that suits your budget, whether that's an affordable option or a more upscale retreat.
  3. Decide how long to go for: Now that you're up to speed on Mesi, you can figure out the ideal length of your vacation. Put together a rough plan and allocate enough time to cover everything you want to do.
  4. Bundle your bookings: With your travel dates in order, you can combine your car rental, flights, hotels and more into a customized Mesi vacation package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.