Title: Best Hotels Near Mercy Hospital Jefferson, from CA $126 | Expedia.ca [Missouri Travel Guide](https://expedia.ca/Missouri.dx227)[Vacation Rentals in Missouri](https://expedia.ca/Destinations-In-Missouri.d227.Vacation-Rental-Destinations)[Flights to Missouri](https://expedia.ca/Destinations-In-Missouri.d227.Flight-Destinations)[Things to do in Missouri](https://expedia.ca/Things-To-Do-In-Missouri.d227.Travel-Guide-Activities)[Mercy Hospital Jefferson Car Rentals](https://expedia.ca/Car-Rentals-In-Mercy-Hospital-Jefferson.d553248635997986709.Car-Rental-Guide)[Mercy Hospital Jefferson Vacations](https://expedia.ca/Mercy-Hospital-Jefferson-Missouri.d553248635997986709.Vacation-Attraction) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near Mercy Hospital Jefferson, from CA $126 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Sep 26 - Sep 27](https://www.expedia.ca/Hotel-Search?regionId=553248635997986709&startDate=2025-09-26&endDate=2025-09-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248635997986709&startDate=2025-09-27&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248635997986709&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635997986709&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Top Hotels Close to Mercy Hospital Jefferson ![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/720261dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/6d872386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/w7137h4758x0y0-7ae60078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2700000/2699400/2699317/77434452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG 2.1 km from Mercy Hospital Jefferson 9.4/10 Exceptional (683) "Great place to stay!" CA $194 CA $222 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Farmington-Hotels-Holiday-Inn-Express-Hotel-Suites-FESTUS-SOUTH-ST-LOUIS.h2699317.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/1887aa70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/a1c40704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/e66aa4eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/6e70629c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Festus - St. Louis South 2.1 km from Mercy Hospital Jefferson 8.0/10 Very good (857) "Great easy place to stay. Good location." CA $153 CA $175 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/3ea7ebcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/fc42ec39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/70be7941.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/40200/40138/4d9ecdd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Festus - St Louis South 2.3 km from Mercy Hospital Jefferson 8.0/10 Very good (880) "The stay and food " CA $108 CA $126 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information) ![Gift shop](https://images.trvl-media.com/lodging/7000000/6060000/6058000/6057984/c29b94f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Roever Room](https://images.trvl-media.com/lodging/7000000/6060000/6058000/6057984/b0233202.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Loft Suite](https://images.trvl-media.com/lodging/7000000/6060000/6058000/6057984/bfc4ab94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![McRoberts Room](https://images.trvl-media.com/lodging/7000000/6060000/6058000/6057984/f44f88b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Corner George Inn Bed & Breakfast 14.3 km from Mercy Hospital Jefferson 9.0/10 Wonderful (153) "Hosts were excellent, very quiet and the breakfast was wonderful" CA $158 CA $176 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Maeystown-Hotels-Corner-George-Inn-Bed-Breakfast.h6057984.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-10&endDate=2025-10-11®ionId=553248635997986709&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMercy-Hospital-Jefferson-Hotels.0-l553248635997986709-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMercy-Hospital-Jefferson-Hotels.0-l553248635997986709-0.Travel-Guide-Filter-Hotels) ## Top Mercy Hospital Jefferson Hotel Reviews ![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](//images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c_y.jpg) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham 10/10 Excellent "Was very happy with our stay. Our suite was well worth the very reasonable price. King Bed was very comfortable. AC was a little noisy but no issues." [](https://expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ![Pear Tree Inn St. Louis Arnold](//images.trvl-media.com/lodging/1000000/50000/40200/40112/d33a8d98_y.jpg) ### Pear Tree Inn St. Louis Arnold 10/10 Excellent "Friendly and clean." [](https://expedia.ca/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Arnold.h40112.Hotel-Information) ![River City Casino & Hotel](//images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/33f9207d_y.jpg) ### River City Casino & Hotel 10/10 Excellent "Very nice, clean. Good casino" [](https://expedia.ca/St-Louis-Hotels-River-City-Casino-Hotel.h6456459.Hotel-Information) ![Holiday Inn Express & Suites St. Louis South - I-55 by IHG](//images.trvl-media.com/lodging/19000000/18060000/18057900/18057879/24d3d68a_y.jpg) ### Holiday Inn Express & Suites St. Louis South - I-55 by IHG 10/10 Excellent "My stay was awesome! Everything was great! Staff so awesome! Friendliest hotel I’ve ever stayed at! A+" [](https://expedia.ca/St-Louis-Hotels-Holiday-Inn-Express-Suites-St-Louis-South-I-55.h18057879.Hotel-Information) ![Postcard Cabins St. Francois](//images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/3b6f469d_y.jpg) ### Postcard Cabins St. Francois 10/10 Excellent "This is the perfect getaway to disconnect from the real world and reconnect to your love ones. We loved our cabin and will definitely be coming back! " [](https://expedia.ca/French-Village-Hotels-Postcard-Cabins-St-Francois.h110550817.Hotel-Information) ![Comfort Inn Festus - St Louis South](//images.trvl-media.com/lodging/1000000/50000/40200/40138/3ea7ebcc_y.jpg) ### Comfort Inn Festus - St Louis South 10/10 Excellent "This hotel was a good place to stay and will be coming back. The staff were really friendly and polite. Convenient to restaurants and other stores. The only thing that we didn’t like was how there is no pool. What happened to every hotel having a pool lol. " [](https://expedia.ca/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information) ![Fairfield Inn & Suites by Marriott St. Louis South](//images.trvl-media.com/lodging/58000000/57110000/57104000/57103908/79ccdde7_y.jpg) ### Fairfield Inn & Suites by Marriott St. Louis South 10/10 Excellent "Everything was perfect except the bed. (But I just prefer softer like my bed at home). Superb service from check in to check out! I believe the gentlemans name was Brad. Sharp dressed and very friendly and accommodated us since we arrived a few minutes early. We were in town for a cardinals ballgame, and we will definitely stay here again. Nice breakfast area and many options. " [](https://expedia.ca/St-Louis-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Louis-South.h57103908.Hotel-Information) ![Hampton Inn & Suites St. Louis/South I-55](//images.trvl-media.com/lodging/4000000/3790000/3787100/3787094/8b6f2fed_y.jpg) ### Hampton Inn & Suites St. Louis/South I-55 10/10 Excellent "Really nice rooms and staff , good breakfast!" [](https://expedia.ca/St-Louis-Hotels-Hampton-Inn-Suites-StLouis-South-At-I-55.h3787094.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Festus - St. Louis South](//images.trvl-media.com/lodging/1000000/50000/42200/42120/1887aa70_y.jpg) ### La Quinta Inn & Suites by Wyndham Festus - St. Louis South 10/10 Excellent "Great easy place to stay. Good location." [](https://expedia.ca/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information) ### Hotels near Other Attractions [](https://expedia.ca/Villa-Antonio-Winery-Hotels.0-l553248621532648571-0.Travel-Guide-Filter-Hotels) #### Villa Antonio Winery You can enjoy a tasting or tour at Villa Antonio Winery during your travels to Hillsboro. Discover the area's countryside and churches. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532648571) ## Frequently asked questions ### What's the area like around Mercy Hospital Jefferson? > Mercy Hospital Jefferson is located in Crystal City. You'll find 12 hotels and other accommodations within a few miles for a convenient home base. ### Where is the best place to stay near Mercy Hospital Jefferson? > [La Quinta Inn & Suites by Wyndham Festus - St. Louis South](https://www.expedia.ca/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 1.3 mi (2.1 km) from Mercy Hospital Jefferson. Other good choices within 5 miles include [Comfort Inn Festus - St Louis South](https://www.expedia.ca/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information) and [Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG](https://www.expedia.ca/Farmington-Hotels-Holiday-Inn-Express-Hotel-Suites-FESTUS-SOUTH-ST-LOUIS.h2699317.Hotel-Information). ### How many hotels will I be able to find close to Mercy Hospital Jefferson? > Expedia has 12 hotels and other accommodations a few miles from Mercy Hospital Jefferson. ### If I need to cancel the hotel reservation for my stay near Mercy Hospital Jefferson, will I receive a refund? > Yes! Most hotel bookings are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the best options available near Mercy Hospital Jefferson. ### Where can I learn more about changing or cancelling my trip in the area near Mercy Hospital Jefferson? > To access more information about picking new dates or cancelling your stay near Mercy Hospital Jefferson, head over to [our customer service page](https://www.expedia.com/service/). ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [5 Star Hotels in Herculaneum](https://www.expedia.ca/5Star-Herculaneum-Hotels.s50-0-d3000349395.Travel-Guide-Filter-Hotels) - [Aparthotels in Arnold](https://www.expedia.ca/Arnold-Apart-Hotels.d177608-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Arnold](https://www.expedia.ca/Arnold-Bed-And-Breakfast.d177608-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Chalets in Arnold](https://www.expedia.ca/Arnold-Chalets.d177608-aaChalets.Travel-Guide-Accommodation) - [Cheap Hotels in Arnold](https://www.expedia.ca/Arnold-Hotels-Cheap-Hotels.0-0-d177608-tCheapHotels.Travel-Guide-Filter-Hotels) - 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