As Meekatharra is a small, regional town, the "best" area to stay is generally considered to be within the main township itself, close to the services and amenities available.
The town centre, primarily around High Street and the surrounding blocks, is where you'll find the limited accommodation options, such as the local hotel and motels. This area provides convenient access to the general store, fuel stations, and the Meekatharra Roadhouse, which are essential for travellers passing through.
For those on a road trip, staying within the main township is highly practical. It allows for easy resupply, a comfortable overnight stop, and straightforward access back to the main roads for your onward journey.