Medical District Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to CA $1,096 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Top Holiday Package Deals in Medical District

Price found within the past 48 hours. Click for updated prices.
Hotel Napoleon Memphis

Hotel Napoleon Memphis

4 out of 5
Downtown Memphis
per person
Sep 22 - Sep 26
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to Memphis (MEM)
8.6/10 Excellent! (915 reviews)
The pictures of this hotel are significantly better than how the hotel actually looks. It’s a nice hotel overall but some areas are dated and need fresh paint. When I stayed here I was told the bar/restaurant was being renovated so it would be only open for the continental breakfast. The “breakfast” consisted of stale danishes, muffins, juice, granola and yogurt. No serving utensils and an extremely limited amount. Once the single platefuls were gone, they stated that was all they had, regardless of how many guests they had. Parking was in a deck next door and was an inconvenience because you have to call or text the company to be let out of the gate each time you had to exit. Overall it’s a decent hotel and I would stay here again only for 1 or 2 days.

Reviewed on Jun. 28, 2025

Hilton Garden Inn Memphis East Germantown, TN

Hilton Garden Inn Memphis East Germantown, TN

3 out of 5
per person
Sep 22 - Sep 26
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to Memphis (MEM)
8.8/10 Excellent! (413 reviews)
We liked the hotel except for the moldy shower. The pool was green but obviously out of service. The stay was ok, just not worth the price. Hiltons are usually much better. Conveniently located.

Reviewed on Jun. 1, 2025

River Inn of Harbor Town

River Inn of Harbor Town

4 out of 5
Mud Island
per person
Sep 22 - Sep 26
found 3 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to Memphis (MEM)
9.6/10 Exceptional! (769 reviews)
Beautiful hotel and surrounding area. Staff were great. The food was delicious.

Reviewed on Jun. 30, 2025

Barsala At The Nine @ Memphis

Barsala At The Nine @ Memphis

4 out of 5
East Memphis
per person
Sep 2 - Sep 5
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to Memphis (MEM)
No reviews
Embassy Suites by Hilton Memphis East Germantown Area

Embassy Suites by Hilton Memphis East Germantown Area

3.5 out of 5
per person
Sep 22 - Sep 26
found 3 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to Memphis (MEM)
8.6/10 Excellent! (261 reviews)
Was nice exactly as expected

Reviewed on Jul. 15, 2025

Where to stay in Medical District

Find the best Medical District areas and neighborhoods for the activities you enjoy most. Learn more about Medical District
Default Image

Downtown Memphis

4 out of top 10 points of interest in this area
4/5(87 area reviews)

Home to the Memphis Redbirds and Grizzlies NBA team, this central business district offers entertainment, dining, and attractions like Beale Street, FedExForum, and AutoZone Park. Easily accessible via major highways and public transit options.

Find hotels in Downtown Memphis

Medical District Hotel Deals

Motel 6 Memphis, TN - Downtown

Motel 6 Memphis, TN - Downtown

2 out of 5
210 S Pauline St, Memphis, TN
Fully refundableReserve now, pay when you stay
The price is CA $79 per night from Jul 17 to Jul 18
CA $79
CA $96 total
Jul 17 - Jul 18
includes taxes & fees
5.6/10 (1,010 reviews)
Oasis in the middle of an urban jungle…
"It’s in a bad part of town but it’s the rooms are immaculate and well taken care of…"

Reviewed on Jul. 12, 2025

Motel 6 Memphis, TN - Downtown
Memphis Vitality Hotel

Memphis Vitality Hotel

4 out of 5
2625 Thousand Oaks Blvd, Memphis, TN
Fully refundableReserve now, pay when you stay
The price is CA $123 per night from Jul 23 to Jul 24
CA $123
CA $162 total
Jul 23 - Jul 24
includes taxes & fees
8.6/10 Excellent! (803 reviews)
"Great stay"

Reviewed on Jul. 13, 2025

Memphis Vitality Hotel
Hu. Hotel

Hu. Hotel

3.5 out of 5
79 Madison Avenue, Memphis, TN
Fully refundableReserve now, pay when you stay
The price is CA $138 per night from Aug 2 to Aug 3
CA $138
CA $170 total
Aug 2 - Aug 3
includes taxes & fees
8.2/10 Very Good! (1,282 reviews)
"Staff was exceptionally attentive and the area was super convenient to walk. Great views of the river as well! As a solo traveler, I felt cared for and safe."

Reviewed on Jul. 16, 2025

Hu. Hotel
See all 1,558 properties in Medical District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Frequently asked questions

How much does a Medical District vacation package cost?
Our Medical District packages, which start from just CA $914, are an easy way to save big bucks. All you have to do is choose your preferred hotels, flights and more to create your ideal trip.
How do I get a cheap travel package to Medical District?
Combine your bookings with Expedia to save big on your next adventure. With over 550 partner airlines and 1,000,000 hotel options worldwide, your Medical District vacation package can be customized exactly to suit your travel style. With all those extra dollars, why not include a few awesome experiences and tours? It's an easy way to unlock even more savings. That dream vacation to Medical District is much closer than you thought!
Where should I stay in Medical District?
Visitors come from near and far to experience Graceland and Memphis Zoo in Medical District. Book a hotel within walking distance of these popular attractions and visit them whenever you want.
What are the top hotels in Medical District?
Secure a room at Motel 6 Memphis, TN - Downtown. It's one of the area's most sought-after hotels. Another great option in Medical District is Downtown Memphis Shellcrest Apartments.
How far in advance should I book my Medical District vacation?
It's hard to pick the perfect time for airfares, but we generally suggest the earlier, the better. Most international journeys on Expedia become available to compare up to a year in advance. If you're unable to do so, don't fret. Cheap prices occasionally appear just weeks before departure dates.
What does an Expedia Medical District travel package include?
Hotels, flights and rental cars --- you'll discover them all here. With Expedia, you can create your Medical District travel package just how you like it. All you have to do is figure out just what you need. Once you've made your booking, you can add extras like activities and experiences. The more you bundle, the bigger the savings!
What should I know before booking a Medical District travel package?
You'll score amazing savings when you combine your hotels, flights and rental cars into a package. Plus, booking everything in one spot makes trip planning much easier. So why waste your money or time? Whether you're organizing a luxury romantic escape or a low-cost family road trip, explore our package deals today.
Can I choose my airline with a Medical District Expedia vacation package?
Yes, the choice is all yours. We offer more than 550 airlines all over the world, so you can tailor your Medical District adventure according to your budget and needs.
If I'm not able to travel, can I cancel my Medical District vacation package?
It's difficult to predict what tomorrow might bring, so it's comforting to know that you can change or cancel your Medical District vacation package. If you made your booking in the last 24 hours, you may be eligible for a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Check our Customer Service Portal to learn more.

Things to do

Memphis Hop On and Hop Off Tour

Memphis Hop On and Hop Off Tour

CA $68
per adult
Memphis Hop On and Hop Off Tour
1.5-Hour Public Party Bike Ride in Downtown Memphis

1.5-Hour Public Party Bike Ride in Downtown Memphis

CA $55
per adult
1.5-Hour Public Party Bike Ride in Downtown Memphis
Memphis: Guided Bar Crawl on a Pedal Bike

Memphis: Guided Bar Crawl on a Pedal Bike

CA $55
per adult
Memphis: Guided Bar Crawl on a Pedal Bike
See all activities in Memphis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.