Medical Center District Vacation Packages
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Top Holiday Package Deals in Medical Center District
Price found within the past 48 hours. Click for updated prices.
Hallmark Inn and Suites
Park Village
Price was CA $793, price is now CA $690 per person
CA $690
per person
Sep 1 - Sep 6
found 24 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to San Antonio (SAT)
8.6/10 Excellent! (167 reviews)
I recommend checking in before 9PM for a better experience, but the staff and property were nice and accommodating.
Reviewed on Jun 20, 2026
Staybridge Suites San Antonio by IHG
Uptown
Price was CA $1,159, price is now CA $981 per person
CA $981
per person
Sep 1 - Sep 6
found 24 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to San Antonio (SAT)
8.4/10 Very Good! (1,005 reviews)
I have to say, the night shift receptionist was the nicest, kindest person ever. In all the hotels we’ve ever stayed at, she treated us the best. She was very professional and made sure we were attended right away and was so sweet. I would stay here again just because of she treated my family and I. I didn’t get her name but she has short hair.
Reviewed on Jun 13, 2026
Hotel Valencia Riverwalk
Downtown San Antonio
Price was CA $1,227, price is now CA $1,050 per person
CA $1,050
per person
Sep 1 - Sep 6
found 24 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to San Antonio (SAT)
9.4/10 Exceptional! (2,810 reviews)
I've stayed on the Riverwalk more times than I can count. But I'll count Valencia as the number one stay. It's beautiful, it smells amazing (not something you typically say about a hotel), and it was my favorite location. Close enough to the Riverwalk fun fun (just a short walk), and far enough away to be really peaceful and quiet. We had the courtyard view, which we LOVED. HIGHLY recommend The Valencia.
Reviewed on Jun 20, 2026
San Antonio Marriott Northwest Medical Center
Medical Center District
Price was CA $1,021, price is now CA $902 per person
CA $902
per person
Sep 1 - Sep 6
found 24 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to San Antonio (SAT)
8.6/10 Excellent! (1,076 reviews)
Solid property that covers the basics very well. Easy checkin/checkout, plenty of parking, and in a central location. The hotel looked like it had event spaces so in general it felt spacious and there was always a steady flow of people.
Reviewed on Jun 15, 2026
Where to stay in Medical Center District
Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Downtown San Antonio
4 out of top 10 points of interest in this area
4/5(212 area reviews)
Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.
Medical Center District Hotel Deals
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $126 per night from Jun 22 to Jun 23
CA $126
CA $149 total
Jun 22 - Jun 23
includes taxes & fees
8.4/10 Very Good! (3,445 reviews)
"We wouldn’t stay here again. The room was just okay :/ The shower had lukewarm water at best, showers were cold and uncomfortable. Breakfast was disgusting. The eggs tasted like the pan they had been cooked in. They were inedible and extremely greasy. The bedroom linens were very obviously stained. ..."
Reviewed on Jun 21, 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $155 per night from Jul 5 to Jul 6
CA $155
CA $184 total
Jul 5 - Jul 6
includes taxes & fees
8.6/10 Excellent! (1,081 reviews)
"The hotel was great, booked the hotel for a family trip and my family loved the hotel. The lounge area is gorgeous. I would definitely recommend this hotel!"
Reviewed on Jun 18, 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $127 per night from Jul 7 to Jul 8
CA $127
CA $151 total
Jul 7 - Jul 8
includes taxes & fees
9.2/10 Wonderful! (1,345 reviews)
"Staff was friendly. I had read reviews about the elevator and not working before arrival so was aware. Thankfully we were only on the second floor so just took the stairs. The pool was so crowded both nights"
Reviewed on Jun 21, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Medical Center District
USAA Corporate Office Headquarters
USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.
Things to do
San Antonio Zoo Any Day Ticket
CA $41
per adult
96% of travellers recommend
San Antonio: Fredericksburg Wineries Day Trip with Tastings
CA $248
per adult
100% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.