Medical Center District Vacation Packages

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Top Holiday Package Deals in Medical Center District

Price found within the past 48 hours. Click for updated prices.
Sonesta ES Suites San Antonio Downtown Alamo Plaza

Sonesta ES Suites San Antonio Downtown Alamo Plaza

3 out of 5
Downtown San Antonio
Price was CA $1,239, price is now CA $934 per person
CA $934
per person
Oct 23 - Oct 27
found 23 hours ago
Roundtrip non-stop flight included
Montreal (YUL) to San Antonio (SAT)
8.4/10 Very Good! (1,732 reviews)
Breakfast was good and the rooms was good and quiet will definitely stay there again

Reviewed on Sep. 6, 2025

La Cantera Resort & Spa

La Cantera Resort & Spa

4 out of 5
La Cantera District
Price was CA $1,557, price is now CA $1,139 per person
CA $1,139
per person
Oct 9 - Oct 12
found 5 hours ago
Roundtrip non-stop flight included
Montreal (YUL) to San Antonio (SAT)
9/10 Wonderful! (1,017 reviews)
Spa and pools were best in Central Texas will stay again soon!

Reviewed on Sep. 3, 2025

Hotel Havana

Hotel Havana

3.5 out of 5
Downtown San Antonio
Price was CA $2,120, price is now CA $1,584 per person
CA $1,584
per person
Oct 30 - Nov 3
found 1 day ago
Roundtrip non-stop flight included
Québec (YQB) to San Antonio (SAT)
9/10 Wonderful! (1,003 reviews)
Beautiful, historic hotel! The staff was super friendly and helpful! It’s in a quiet part of the Riverwalk, limited dining options within walking distance, but I would definitely stay here again!

Reviewed on Aug. 25, 2025

Tapatio Springs Hill Country Resort

Tapatio Springs Hill Country Resort

4 out of 5
Price was CA $1,917, price is now CA $1,439 per person
CA $1,439
per person
Oct 30 - Nov 3
found 1 day ago
Roundtrip non-stop flight included
Québec (YQB) to San Antonio (SAT)
8.6/10 Excellent! (802 reviews)
The new clubhouse is new but the rooms and buildings are old and in bad condition.

Reviewed on Sep. 1, 2025

Hacienda del Rio

Hacienda del Rio

2 out of 5
Price was CA $1,451, price is now CA $1,098 per person
CA $1,098
per person
Nov 23 - Nov 30
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to San Antonio (SAT)
9.2/10 Wonderful! (175 reviews)
Loved our stay. A very chill and relaxing hotel! The hotel is steps from the river. Has all the amenities you need!!

Reviewed on Sep. 7, 2025

Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Downtown - Riverwalk showing heritage architecture, boating and a river or creek

Downtown San Antonio

4 out of top 10 points of interest in this area
4/5(209 area reviews)

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Find hotels in Downtown San Antonio

Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is CA $123 per night from Sep 8 to Sep 9
CA $123
CA $145 total
Sep 8 - Sep 9
includes taxes & fees
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is CA $121 per night from Sep 11 to Sep 12
CA $121
CA $143 total
Sep 11 - Sep 12
includes taxes & fees
San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 out of 5
7203 Wurzbach Road, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is CA $127 per night from Sep 14 to Sep 15
CA $127
CA $149 total
Sep 14 - Sep 15
includes taxes & fees
Fairfield Inn & Suites by Marriott San Antonio Medical Center
See all 4,591 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does a Medical Center District vacation package cost?
Starting from just CA $934, a vacation package is your passport to low-priced travel. Create your own Medical Center District adventure by picking from our huge range of airfares, hotels and rental cars.
How do I get a cheap travel package to Medical Center District?
It's as simple as bundling. Hotels, rental cars and flights — combine whatever you need into a Medical Center District vacation package and save. Score even better deals when you include extras such as activities or tours to your booking. But that's not the only good part. You have the freedom to customize your vacation your own way. We offer over 550 airlines and 1,000,000 properties throughout the world, so that everyone has a chance to travel and fulfill those vacation dreams.
Where should I stay in Medical Center District?
Make a reservation just around the corner from Six Flags Fiesta Texas, one of this area's most well-known attractions. It's the ideal spot for serious sightseers.
What are the top hotels in Medical Center District?
Amazing, Contemporary, Beautiful and Fairfield Inn & Suites by Marriott San Antonio Medical Center are two of the most well-known hotels in Medical Center District. Why not take a look at the amenities and rates at each and then make up your mind?
How far in advance should I book my Medical Center District vacation?
It all depends on the airline, but it's usually possible to look up international fares on Expedia up to 12 months in advance. While it's generally recommended to book ahead of time, lucky customers will sometimes nab a cheaper ticket just weeks before the date of departure.
What does an Expedia Medical Center District travel package include?
Flights, car rentals and hotels — we connect you to the very best deals. All you'll have to do is figure out your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and sightseeing tours. Our travel packages make it easy to customize an exciting Medical Center District vacation.
What should I know before booking a Medical Center District travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fantastic discounts. You're not limited to hotels, however. Book with us and select from island resorts, city apartments and just about everything in between!
Can I choose my airline with a Medical Center District Expedia vacation package?
Yes, you're in charge. We have access to over 550 partner airlines globally, so you can tailor your Medical Center District trip according to your budget and travel needs.
If I'm not able to travel, can I cancel my Medical Center District vacation package?
Whether it's your hotel or flight, you can cancel or change it. Booked your Medical Center District vacation package in the last 24 hours? You may be able to make any changes for free. For bookings made more than 24 hours ago, you may be charged a fee by your airline, hotel or car rental company. For more information, head to our Customer Service Portal. We're here to help you every step of the way.

Discover the most popular places to visit in Medical Center District

USAA Corporate Office Headquarters

USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.

USAA Corporate Office Headquarters

Things to do

San Antonio: Discovery Tour at Natural Bridge Caverns

San Antonio: Discovery Tour at Natural Bridge Caverns

CA $49
per adult
92% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
SEA LIFE San Antonio

SEA LIFE San Antonio

CA $34
per adult
78% of travellers recommend
SEA LIFE San Antonio
San Antonio: Tower of the Americas Entry Ticket

San Antonio: Tower of the Americas Entry Ticket

CA $29
per adult
San Antonio: Tower of the Americas Entry Ticket
See all activities in San Antonio
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.