
Medical Center District Vacation Packages
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Top Holiday Package Deals in Medical Center District
Price found within the past 48 hours. Click for updated prices.

Tx Home Group- San Antonio
Midtown
Price was CA $1,410, price is now CA $1,000 per person
CA $1,000
per person
May 24 - May 28
found 3 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to San Antonio (SAT)
9.8/10 Exceptional! (7 reviews)
Nightclub area; noisy at night at times; no close shopping; highway driving across town.
Initial instructions were confusing but host was great. Pool and gym access; good for active people.
Reviewed on Mar 14, 2026

Hyatt Regency Hill Country Resort and Villas
Far West Side
Price was CA $1,814, price is now CA $1,340 per person
CA $1,340
per person
May 24 - May 28
found 3 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to San Antonio (SAT)
8.8/10 Excellent! (1,000 reviews)
We had a great 3 nights of vacation at this property. My 5yr old daughter had a blast enjoying the lazy river and the warm pool, and so did I! It was great to have the pool set in a natural setting under trees, etc - beautiful experience. The lagoon was great too. I liked that they put together so many activities, especially for kids, and shared an itinerary of events for the whole week - it made it so much easier for us to plan our days. The room itself was very comfortable…we enjoyed the balcony with views of the greenery around. We had a wonderful lunch at the Springhouse Cafe one of the days. Since we were vegetarians we didn’t bother much with the other restaurants. But within 10-15 mins driving distance there were a few good options. I loved that all the staff badges show where they were from. I thought that was a great touch and allowed for warm conversations and made the interactions personable!
Overall, it is an excellent property. It is a no-brainer to stay here especially if you have kids. We would gladly recommend this to anyone, amd would love to come back here!
Reviewed on Apr 7, 2026

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Far West Side
Price was CA $1,420, price is now CA $1,058 per person
CA $1,058
per person
Jun 23 - Jun 27
found 23 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to San Antonio (SAT)
9/10 Wonderful! (1,541 reviews)
The home was clean and completely ready for guests. Beautiful,
Reviewed on Apr 19, 2026

Signia by Hilton La Cantera Resort & Spa
La Cantera District
Price was CA $1,962, price is now CA $1,503 per person
CA $1,503
per person
May 30 - Jun 4
found 24 hours ago
Roundtrip non-stop flight included
Calgary (YYC) to San Antonio (SAT)
9/10 Wonderful! (1,024 reviews)
Clean room and friendly staff. Everyone on the property always has a big smile!
Reviewed on Apr 12, 2026

Thompson San Antonio - Riverwalk, by Hyatt
Downtown San Antonio
Price was CA $1,486, price is now CA $1,162 per person
CA $1,162
per person
Jun 23 - Jun 25
found 21 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to San Antonio (SAT)
9/10 Wonderful! (972 reviews)
Everything about this place was amazing!
Reviewed on Apr 12, 2026
Where to stay in Medical Center District
Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District

Downtown San Antonio
4 out of top 10 points of interest in this area
4/5(212 area reviews)
Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.
Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $122 per night from Apr 21 to Apr 22
CA $122
CA $144 total
Apr 21 - Apr 22
includes taxes & fees
8.4/10 Very Good! (3,295 reviews)
We didn't stay there. We got confused on the freeway during rain and ended up at a different LaQuinta in San Antonio where we spent the night. It was very nice and the staff was professional. The desk clerk did point out that we were at the wrong hotel but it was too late. We had already gone to ...
Reviewed on Apr 19, 2026

San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $162 per night from May 2 to May 3
CA $162
CA $192 total
May 2 - May 3
includes taxes & fees
8.6/10 Excellent! (1,023 reviews)
We paid for king room and when we got there they placed us in 2 double bed room wasn’t too happy about that. Other than that there was old chips behind our bed and old food left under the cabinet by the tv- a little gross. Staff was friendly.
Reviewed on Apr 19, 2026

Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $134 per night from Apr 27 to Apr 28
CA $134
CA $159 total
Apr 27 - Apr 28
includes taxes & fees
8.8/10 Excellent! (1,000 reviews)
It was good ! The mattress was a little soft! But everything else was good!
Reviewed on Apr 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Medical Center District
USAA Corporate Office Headquarters
USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.
Things to do

San Antonio Zoo Any Day Ticket
CA $41
per adult
96% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.











