A calm river surrounded by trees with Spanish moss, reflecting the clear blue sky.

Find Family Hotels in Mayo, FL from CA $114

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Check availability on Mayo Family Hotels

Tonight
Sep 25 - Sep 26
Tomorrow
Sep 26 - Sep 27
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Mayo family-friendly hotels

An aerial view of a campground with RVs, a swimming pool, and tennis courts.
A wooden cabin with a porch, a front door, and a small window.
A serene lakeside campsite with picnic tables and chairs.
A covered outdoor dining area with a table and chairs, large windows, and a view of greenery.

1. Suwannee River Rendezvous

Suwannee River Rendezvous
Mayo
CA $127
CA $170 total
includes taxes & fees
Oct 4 - Oct 5
Suwannee River Rendezvous
A commercial kitchen with coffee machines, a beverage dispenser, and various kitchen appliances.
A hotel room with a desk, chair, TV, microwave, and refrigerator.
A spacious living area with a coffee station, teal sofas, and a ceiling fan.
A modern bathroom with a double sink, a mirror with integrated lighting, a towel rack, and a shelf with neatly folded towels.

2. Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
Live Oak
  • Florida getaway offers outdoor pool, free breakfast, and music park access for memorable family trips.
CA $120
CA $132 total
includes taxes & fees
Oct 4 - Oct 5
Quality Inn & Suites Live Oak I-10 Exit 283
A hotel reception area with a reception desk, seating area, and a view of the parking lot.
A modern bathroom with a glass shower enclosure, a white vanity with a sink, and a large mirror above the vanity.
A reception area with a wooden floor, a reception desk, a seating area with chairs, and a view through the glass doors to the outside.
A hotel room with two beds, a bedside table with a lamp, a phone, and a window with curtains.

3. Econo Lodge Live Oak

Econo Lodge Live Oak
Live Oak
CA $103
CA $114 total
includes taxes & fees
Sep 28 - Sep 29
Econo Lodge Live Oak
A modern hotel with a swimming pool, outdoor seating, and a covered area.
A gym with treadmills, elliptical machines, and stationary bikes, equipped with mirrors and exercise mats.
A hotel room with a bed, a desk, a chair, a TV, a lamp, and a minibar.
A modern kitchen with a white countertop, dark cabinets, and a glass backsplash.

4. Best Western Plus Madison

Best Western Plus Madison
Madison
CA $185
CA $208 total
includes taxes & fees
Oct 6 - Oct 7
Best Western Plus Madison
A small wooden house with a green exterior, a wooden deck, and a staircase leading to the entrance.

5. Nook at the Springs | Tiny Home • Full Kitchen

Nook at the Springs | Tiny Home • Full Kitchen
Fort White
CA $93
CA $234 total
includes taxes & fees
Sep 27 - Sep 28
Nook at the Springs | Tiny Home • Full Kitchen
A room with a ceiling fan, a chessboard, a striped curtain, and a chair.
A living room with a sofa, armchair, coffee table, and a television.
A calm lake with clear water, surrounded by trees and a sandy shore.
An outdoor seating area with a fire pit, surrounded by string lights and potted plants.

6. Peaceful 3BR/2BA Near Suwannee River & Springs

Peaceful 3BR/2BA Near Suwannee River & Springs
Live Oak
CA $108
CA $225 total
includes taxes & fees
Oct 6 - Oct 7
Peaceful 3BR/2BA Near Suwannee River & Springs
A wooden swing set in a park with a fenced area, a wooden structure, and a large tree.
A swimming pool with a covered area, surrounded by trees and a fence.
An outdoor bar area with wooden tables and chairs, umbrellas, and a bar counter.
A marina with docks, boats, and a water tower in the background.

7. Steinhatchee River Inn

Steinhatchee River Inn
Steinhatchee
CA $162
CA $224 total
includes taxes & fees
Oct 5 - Oct 6
Steinhatchee River Inn
A two-story house with a covered porch, a staircase, and a large lawn.
A wooden bar area with a ceiling fan, concrete pillars, and a view of the outdoors.

8. Suwannee River Retreat: Pet Friendly, Private Dock

Suwannee River Retreat: Pet Friendly, Private Dock
Branford
CA $372
CA $869 total
includes taxes & fees
Sep 28 - Sep 29
Suwannee River Retreat: Pet Friendly, Private Dock
A two-story house with a covered porch, a staircase, and a large lawn.
A wooden bar area with a ceiling fan, concrete pillars, and a view of the outdoors.

9. Suwannee River Retreat: Pet Friendly, Private Dock

Suwannee River Retreat: Pet Friendly, Private Dock
Branford
CA $455
CA $857 total
includes taxes & fees
Sep 28 - Sep 29
Suwannee River Retreat: Pet Friendly, Private Dock

10. Coastal Cottage 526 Steinhatchee Florida

Coastal Cottage 526 Steinhatchee Florida
Steinhatchee
CA $212
CA $372 total
includes taxes & fees
Sep 27 - Sep 28
Coastal Cottage 526 Steinhatchee Florida
View all properties

Choose what matters most at family-friendly hotels in Mayo

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Top Mayo Hotel Reviews

Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283

10/10 Excellent
"Okey"
Rolando 1-night trip
Posted 3 days ago
Quality Inn & Suites Live Oak I-10 Exit 283
Days Inn by Wyndham Madison

Days Inn by Wyndham Madison

8/10 Good
"I chose this hotel because it was close to the highway and the pictures looked good. I did find my room to be fairly well appointed, although there was a space for a microwave, but none there. There is a microwave in the lobby. I was comfortable and enjoyed the bagel and juice and coffee for breakfast. It was kind of strange that the first room I was assigned to was not vacated. The lobby host was very apologetic and gave me a different room. Also, there were highway construction workers staying there, and they were hanging out on the stairs right outside my room, joking around and some smoking pot. That made me feel a little uncomfortable, but I just happened to get the room right by where they were. I could’ve easily landed somewhere where I felt more comfortable."
Paige 1-night trip
Posted 6 days ago
Days Inn by Wyndham Madison

Frequently asked questions

What's Mayo like for family-friendly vacations?
The destination of Mayo is a great choice if you've been thinking about a vacation with your kids. The parks here makes this a great vacation spot for families.
When's the best time to book a family-friendly vacation in Mayo?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for Mayo is 51 inches.
What's there to see and do with your family in Mayo?
While you and the family are vacationing in Mayo, you might want to check out some of the attractions here such as Lafayette County Library, Suwannee River, and Veteran's Memorial Park of Mayo. Make sure you have lots of time for activities like Steinhatchee Falls and Suwannee River State Park.

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