The best area to stay in Marathon is along the main US-1 Overseas Highway, particularly around the central districts of Marathon and Key Colony Beach.Marathon, the largest city in the Middle Keys, offers a good balance of convenience and access to attractions. The main thoroughfare, US-1 Overseas Highway, runs directly through it, making it easy to get around. You'll find a variety of hotels, holiday rentals, and restaurants dotted along or just off this highway. It's home to the Dolphin Research Centre and the Turtle Hospital, two popular animal rescue centres.For families, staying in Marathon offers excellent access to family-friendly activities. The area around Sombrero Beach is particularly appealing, with its sandy shores and clear waters superb for swimming and building sandcastles. Many holiday rentals here come with private pools and direct access to the water, which is ideal for a relaxed family holiday.Key Colony Beach, a distinct municipality just east of Marathon, is a fantastic option for couples looking for a more relaxed and upscale experience. This small island community is known for its beautiful canals, well-maintained properties, and a more residential feel. It's a quiet area with lovely beaches like Sunset Park, superb for watching the evening sky.