Name: 21C Museum Hotel St Louis
Price range: CA $231
Rating: 9

Your Manchester Vacation

The stress-free way to experience this lively city is with a custom-made Manchester vacation package. Base yourself in the neighborhood of Maplewood, which is great for bars and pubs, gift and craft shops and dining or go someplace else — our packages are all about you. Any trip to Manchester needs a well-designed itinerary. Fill yours with famous sights like Magic House - St. Louis Childrens Museum, Museum of Transportation and Westfield Chesterfield Mall. Browse Expedia's wide range of travel options and start organizing your ideal vacation to Manchester now.

Top Manchester Vacation Deals

Price found within the past 48 hours. Click for updated prices.

The Cheshire

CA $938

per person

Jun 21 - Jun 24

found 1 day ago

Roundtrip non-stop flight included

Vancouver (YVR) to St. Louis (STL)

8.8/10 Excellent! (1,006 reviews)

It has a very quaintly English theme. Very unique and fun.

Reviewed on May 8, 2026

The Royal Sonesta Chase Park Plaza St. Louis

Central West End

CA $1,001

per person

Jun 21 - Jun 24

found 1 day ago

Roundtrip non-stop flight included

Vancouver (YVR) to St. Louis (STL)

9/10 Wonderful! (1,011 reviews)

This was a weekend staycation for my wife and I and as usual we were not disappointed. Very helpful staff and excellent accommodations.

Reviewed on May 4, 2026

Tru By Hilton St. Louis Downtown

Downtown West

CA $1,006

per person

Jun 21 - Jun 24

found 1 day ago

Roundtrip non-stop flight included

Vancouver (YVR) to St. Louis (STL)

7.6/10 Good! (723 reviews)

We loved our stay here! Will definitely be back. The rooms were clean and the beds were comfy. It was a great price, too!!

Reviewed on May 7, 2026

Hilton St. Louis at the Ballpark

Downtown St. Louis

CA $1,270

per person

Jun 21 - Jun 24

found 1 day ago

Roundtrip non-stop flight included

Vancouver (YVR) to St. Louis (STL)

7.6/10 Good! (1,125 reviews)

The staff was incredible. They helped get our bags in and out of the room

Reviewed on May 5, 2026

Home2 Suites by Hilton St. Louis Downtown

Downtown West

CA $1,020

per person

Jun 21 - Jun 24

found 1 day ago

Roundtrip non-stop flight included

Vancouver (YVR) to St. Louis (STL)

8/10 Very Good! (750 reviews)

The rooms were clean. The breakfast was very good with a nice selection of food to choose from. The staff was very helpful and friendly.

Reviewed on May 7, 2026

Ready to book your vacation to Manchester?

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Manchester Hotel Deals

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO

Fully refundableReserve now, pay when you stay

CA $173

CA $204 total

May 25 - May 26

includes taxes & fees

8.6/10 Excellent! (4,060 reviews)

Very clean

Reviewed on May 8, 2026

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO

Fully refundableReserve now, pay when you stay

CA $136

CA $158 total

May 17 - May 18

includes taxes & fees

8.8/10 Excellent! (3,194 reviews)

None

Reviewed on May 8, 2026

21C Museum Hotel St Louis

1528 Locust street St. Louis MO

Fully refundableReserve now, pay when you stay

CA $231

CA $277 total

May 10 - May 11

includes taxes & fees

9/10 Wonderful! (1,823 reviews)

Really cool hotel with great onsite bar/restaurant, gym, pool and art gallery.

Reviewed on May 6, 2026

See all 1,925 properties in Manchester

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.