Title: Best Hotels Near Main Street Hyannis, Hyannis from CA $110 | Expedia.ca

  

[Hyannis Travel Guide](https://expedia.ca/Hyannis.dx1544)[Vacation Rentals in Hyannis](https://expedia.ca/Hyannis-Vacation-Rentals.d1544.Travel-Guide-VacationRentals)[Flights to Hyannis](https://expedia.ca/Cheap-Flights-To-Hyannis.d1544.Travel-Guide-Flights)[Things to do in Hyannis](https://expedia.ca/Things-To-Do-In-Hyannis.d1544.Travel-Guide-Activities)[Main Street Hyannis Car Rentals](https://expedia.ca/Car-Rentals-In-Main-Street-Hyannis.d6287458.Car-Rental-Guide)[Main Street Hyannis Vacations](https://expedia.ca/Main-Street-Hyannis-Hyannis.d6287458.Vacation-Attraction)

![Main Street Hyannis featuring street scenes as well as a couple](https://images.trvl-media.com/place/6287458/f083813a-eac6-4b18-a763-a901fa1ed4e5.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find hotels near Main Street Hyannis, Hyannis from CA $110

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## Check prices for these dates

Tonight

[Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=6287458&startDate=2025-10-24&endDate=2025-10-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6287458&startDate=2025-10-25&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6287458&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6287458&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Top Hotels Close to Main Street Hyannis

![Exterior](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/fe11d49f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/8b9d0245.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, Multiple Beds](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/2c353cdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/3ac160a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyannis Travel Inn

0.2 km from Main Street Hyannis

9.6/10

Exceptional

(1005)

"Wonderful stay. Looking forward to our next visit!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Thomas

CA $139

CA $159 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/Hyannis-Hotels-Hyannis-Travel-Inn.h1379109.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/7438dff7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/6d244f7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Studio Suite, 2 Queen Beds, Harbour View | Living area](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/c85afb09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Porch](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/82e4c2e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Anchor In Distinctive Waterfront Lodging

0.6 km from Main Street Hyannis

9.4/10

Exceptional

(1015)

"Beautiful quaint hotel, with a nice view of the water. The place has a pool, a fire pit and nice spacious rooms. Would stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alberto

CA $208

CA $310 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information)

![View from room](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/76dbfadf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/10f6fac9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![VISIONARY KING ELITE](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/82541975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gift shop](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/ff5be5db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Uncommoner Hotel by Reverie Boutique Collection

1.9 km from Main Street Hyannis

9.2/10

Wonderful

(80)

"Great staff, beautiful property"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Margaret

CA $184

CA $210 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/West-Yarmouth-Hotels-Tidewater-Inn.h480770.Hotel-Information)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/dc2c7156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/f6ec329c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/b2eb67f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/f33d73c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Cape Cod-West Yarmouth

1.7 km from Main Street Hyannis

8.8/10

Excellent

(1001)

"Excellent stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Patricia

CA $145

CA $166 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/West-Yarmouth-Hotels-Hampton-Inn-Suites-Cape-Cod-West-Yarmouth.h2558618.Hotel-Information)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/85f07916.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, pub, pub](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/37259fda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/a80381e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/557f1a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bayside Resort Hotel

2.3 km from Main Street Hyannis

8.8/10

Excellent

(1516)

"Perfect location, clean rooms, lots of nice amenities, great parking Highly recommend "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

NANCY

CA $138

CA $175 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/West-Yarmouth-Hotels-Bayside-Resort-Hotel.h896697.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/9f940314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/ce103da5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Two Double Beds](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/85ee8ddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/cddd593a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Doubletree by Hilton Cape Cod - Hyannis

1 km from Main Street Hyannis

8.4/10

Very good

(867)

"Great location, awesome area for amenities, delicious cookies, as usual!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

CA $155

CA $177 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/f7a87ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/d4c5b048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/0231de53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/a26c3d28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn Hyannis - Cape Cod

0.3 km from Main Street Hyannis

8.0/10

Very good

(1001)

"Clean rooms; free parking on site"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Reu Siega

CA $137

CA $157 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/a974137b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/df083265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/dd4b8ad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/9db04da3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Cape Cod Hyannis

2.3 km from Main Street Hyannis

8.8/10

Excellent

(626)

"Nice hotel good breakfast options the mqll is in the back yard and lots of close by food"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lawrence

CA $141

CA $162 total

includes taxes & fees

Nov 16 - Nov 17

[](https://www.expedia.ca/Hyannis-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Cod-Hyannis.h7660.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/741b5772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/35291799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/3225f1fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/0271fbcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyannis Harbor Hotel

0.6 km from Main Street Hyannis

8.0/10

Very good

(1026)

"This property was perfect for our fall weekend visit. We're looking forward to staying during the summer when the Bluewater Grill is open!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer

CA $171

CA $253 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/aa954682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/d3887aa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/efa49ff6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/6cc9c6b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cape Sands Inn

1.9 km from Main Street Hyannis

8.2/10

Very good

(1004)

"I love this hotel clean good up keep "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jerome

CA $109

CA $124 total

includes taxes & fees

Nov 14 - Nov 15

[](https://www.expedia.ca/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/5d7ebe6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/e4d68938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/9d421872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/0a9fa15c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard Resort

0.3 km from Main Street Hyannis

7.6/10

Good

(31)

"Excellent location. Nicely equipped kitchenette."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Daniel

CA $151

CA $173 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information)

![Room, 1 King Bed](https://images.trvl-media.com/lodging/10000000/9720000/9717400/9717349/93894fd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9720000/9717400/9717349/b7b0921f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/10000000/9720000/9717400/9717349/56fb3cfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/10000000/9720000/9717400/9717349/fd5c5eaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyannis Host Inn

1.6 km from Main Street Hyannis

7.8/10

Good

(455)

"Was a very nice stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Luis

CA $148

CA $170 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/Hyannis-Hotels-Hyannis-Host-Inn.h9717349.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/6128ed99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/5c644d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/c18bcef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/99f74591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Hyannis by IHG

2.9 km from Main Street Hyannis

8.2/10

Very good

(961)

"Great place to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lilian

CA $122

CA $139 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Hyannis-Hotels-Holiday-Inn-Hyannis-By-IHG.h12477.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/f7fc1d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/9afdfb4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/ef69e045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/786ccd3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyannis Plaza Hotel

0.9 km from Main Street Hyannis

7.0/10

Good

(939)

"Great place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

mirza

CA $95

CA $123 total

includes taxes & fees

Nov 22 - Nov 23

[](https://www.expedia.ca/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/900000/895300/895210/ef8e0c34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/900000/895300/895210/c720208e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/900000/895300/895210/103e9cdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/895300/895210/929a854e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area

1.5 km from Main Street Hyannis

7.0/10

Good

(1008)

"lots of things nearby easy to get to where you wanted to be "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

june

CA $97

CA $110 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/West-Yarmouth-Hotels-Days-Inn-By-Wyndham-West-YarmouthHyannis-Cape-Cod-Area.h895210.Hotel-Information)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/8200/8135/53ed8649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/8200/8135/1b122287.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/8200/8135/ed873d9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 King Bed, Golf View | View from room](https://images.trvl-media.com/lodging/1000000/10000/8200/8135/1d638eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cape Cod Irish Village

1.4 km from Main Street Hyannis

6.4/10

(1007)

"We go on a September Cape cod golf trip every year and always stay at the Irish village. Great prices, food, and entertainment. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael

CA $160

CA $184 total

includes taxes & fees

Oct 27 - Oct 28

[](https://www.expedia.ca/Hyannis-Hotels-Resort-Conference-Center-At-Hyannis.h8135.Hotel-Information)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/540000/533000/532969/9bb322af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/540000/533000/532969/ac9508eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/540000/533000/532969/6a90b735.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/540000/533000/532969/3b60e727.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Econo Lodge by Choice - Cape Cod

1.5 km from Main Street Hyannis

6.2/10

(493)

"Rooms were dated but very clean. We would definitely stay there again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paul

CA $105

CA $120 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/West-Yarmouth-Hotels-Econo-Lodge.h532969.Hotel-Information)

![House](https://images.trvl-media.com/lodging/116000000/115550000/115540200/115540151/44ad2736.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House](https://images.trvl-media.com/lodging/116000000/115550000/115540200/115540151/19663ef7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House](https://images.trvl-media.com/lodging/116000000/115550000/115540200/115540151/92dddeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House](https://images.trvl-media.com/lodging/116000000/115550000/115540200/115540151/w3000h2101x0y149-a7097f10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Water Access 5-bed 2-bath Retreat

0.6 km from Main Street Hyannis

CA $490

CA $1,292 total

includes taxes & fees

Oct 30 - Oct 31

[](https://www.expedia.ca/Hyannis-Hotels-Water-Access-5-Bed-2-Bath-Retreat.h115540151.Hotel-Information)

![Family House, Private Bathroom, Pool View | Shared kitchen](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/1de4e978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Private Bathroom, Pool View | Terrace/patio](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/4ede3fc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Private Bathroom, Pool View | Shared kitchen](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/4a3b4c38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Private Bathroom, Pool View | Restaurant](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/6936f2b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sal's Place

2.5 km from Main Street Hyannis

CA $560

CA $808 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/Hyannis-Hotels-Sals-Place.h119373964.Hotel-Information)

![Garden](https://images.trvl-media.com/lodging/13000000/12430000/12426900/12426891/00d26354.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 Queen Bed](https://images.trvl-media.com/lodging/13000000/12430000/12426900/12426891/1c660188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/13000000/12430000/12426900/12426891/2b1f0d40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/13000000/12430000/12426900/12426891/6a955bb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Village Inn Cape Cod

6.1 km from Main Street Hyannis

10/10

Exceptional

(221)

"It was so charming, would definitely stay there again! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kyle

CA $236

CA $271 total

includes taxes & fees

Nov 10 - Nov 11

[](https://www.expedia.ca/Yarmouth-Port-Hotels-The-Village-Inn-Cape-Cod.h12426891.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-08&endDate=2025-11-09&regionId=6287458&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Top Main Street Hyannis Hotel Reviews

![Comfort Inn Hyannis - Cape Cod](//images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/f7a87ca8_y.jpg)

### Comfort Inn Hyannis - Cape Cod

10/10 Excellent

"Their continental breakfast had more options than other hotels I’ve booked! Loved the breakfast choices! We enjoyed the food and our stay. Cozy and clean beds and our room ac worked perfectly! "

[](https://expedia.ca/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information)

![Cape Sands Inn](//images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/aa954682_y.jpg)

### Cape Sands Inn

10/10 Excellent

"Clean room nice view"

[](https://expedia.ca/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information)

![SeaCoast Inn](//images.trvl-media.com/lodging/10000000/9410000/9400300/9400206/90-92aafafd_y.jpg)

### SeaCoast Inn

10/10 Excellent

"It was a 2 day stay as we traveled New England for our 25th Anniversary. The hotel was ideally situated for the town of Hyannis! 1 1/2 blocks from the waterfront harbor and 1/2 block from Main Street and the the shops, restaurants, museums, etc. that are based there! Great location! The hotel itself was older but still clean, well kept, and we had nothing bad to say about it, it was just older but was still attractive!"

[](https://expedia.ca/Hyannis-Hotels-SeaCoast-Inn.h9400206.Hotel-Information)

![Hyannis Travel Inn](//images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/fe11d49f_y.jpg)

### Hyannis Travel Inn

10/10 Excellent

"The hotel staff was great! Friendly and helpful. Really near the dock to catch the ferry to Nantucket. "

[](https://expedia.ca/Hyannis-Hotels-Hyannis-Travel-Inn.h1379109.Hotel-Information)

![Fairfield Inn & Suites by Marriott Cape Cod Hyannis](//images.trvl-media.com/lodging/1000000/10000/7700/7660/a974137b_y.jpg)

### Fairfield Inn & Suites by Marriott Cape Cod Hyannis

10/10 Excellent

"We stayed 6 nights. The hotel is very clean,quiet and has a great breakfast! It saves so much time to be able to have breakfast before we leave for the day. Coffee was always ready any time of day. And parking was so easy. They’ve got plenty of parking. It’s a place I’ll stay again for sure "

[](https://expedia.ca/Hyannis-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Cod-Hyannis.h7660.Hotel-Information)

![Margaritaville Resort Cape Cod](//images.trvl-media.com/lodging/1000000/20000/12900/12897/b57e0b1f_y.jpg)

### Margaritaville Resort Cape Cod

10/10 Excellent

"Resort was everything we wanted."

[](https://expedia.ca/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information)

![Hyannis Plaza Hotel](//images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/f7fc1d07_y.jpg)

### Hyannis Plaza Hotel

10/10 Excellent

"Thank you, was good experience. Will stay again and will advise your hotel to my friend and family. "

[](https://expedia.ca/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information)

![Ocean Street Inn on Hyannis Harbor](//images.trvl-media.com/lodging/5000000/4170000/4165800/4165795/cbe333f0_y.jpg)

### Ocean Street Inn on Hyannis Harbor

10/10 Excellent

"When we arrived the hotel looked deserted so I called and found out they seem to have a few properties connected on the street. Mid October is off season so we were moved to the harbor hotel a block away. I was very grateful for this since the other one was a ghost town. Out stay at the harbor hotel was fabulous. Very large rooms, very clean, and all staff were great. This is also located across from the ferry so the location was perfect. We also enjoyed all of the restaurants on the street with Spanky’s being fabulous for their lobster roll. "

[](https://expedia.ca/Hyannis-Hotels-Ocean-Street-Inn-On-Hyannis-Harbor.h4165795.Hotel-Information)

![Hampton Inn & Suites Cape Cod-West Yarmouth](//images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/dc2c7156_y.jpg)

### Hampton Inn & Suites Cape Cod-West Yarmouth

10/10 Excellent

"Excellent stay."

[](https://expedia.ca/West-Yarmouth-Hotels-Hampton-Inn-Suites-Cape-Cod-West-Yarmouth.h2558618.Hotel-Information)

## Hotels near other Main Street Hyannis attractions

[](https://www.expedia.ca/John-F-Kennedy-Hyannis-Museum-Hotels.0-l6070185-0.Travel-Guide-Filter-Hotels)

![John F. Kennedy Hyannis Museum which includes a statue or sculpture](https://images.trvl-media.com/place/6070185/7e9e6a58-eb55-48ff-bc35-a3283de6db0c.jpg)

### John F. Kennedy Hyannis Museum

4.4/5 (259 reviews)

Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6070185)

[](https://www.expedia.ca/Cape-Cod-Maritime-Museum-Hotels.0-l553248635146342095-0.Travel-Guide-Filter-Hotels)

![Hyannis](https://images.trvl-media.com/place/553248635146342095/f4f9f2be-5681-4d82-8f2a-a01d46fc93fc.jpg)

### Cape Cod Maritime Museum

You can spend an afternoon exploring the galleries in Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the seaside in this family-friendly area, or check out its seafood restaurants.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248635146342095)

[](https://www.expedia.ca/St-Francis-Xavier-Church-Hotels.0-l6286986-0.Travel-Guide-Filter-Hotels)

![Hyannis](https://images.trvl-media.com/place/6286986/68f1113f-193c-4991-a964-5912a97a8e48.jpg)

### St. Francis Xavier Church

4.4/5 (45 reviews)

After visiting St. Francis Xavier Church, make a plan to see the other sights and activities in Hyannis. Wander the beautiful beaches and waterfront in this family-friendly area.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6286986)

[](https://www.expedia.ca/John-F-Kennedy-Memorial-Hotels.0-l6286978-0.Travel-Guide-Filter-Hotels)

![John F. Kennedy Memorial which includes flowers](https://images.trvl-media.com/place/6286978/9b85082f-75c6-4ae3-ac16-7a3f1c71a2a9.jpg)

### John F. Kennedy Memorial

4.5/5 (110 reviews)

Take a moment to reflect on John F. Kennedy’s defining role in American politics, as well as his untimely death, at this poignant memorial.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6286978)

[](https://www.expedia.ca/Hyannis-Armory-Hotels.0-l950930054190297088-0.Travel-Guide-Filter-Hotels)

### Hyannis Armory

Learn about the local history of Hyannis when you take a trip to Hyannis Armory. Wander the waterfront and beautiful beaches in the area.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=950930054190297088)

[](https://www.expedia.ca/Hyannis-Youth-Community-Center-Hotels.0-l553248635976357139-0.Travel-Guide-Filter-Hotels)

### Hyannis Youth & Community Center

You can take time to visit Hyannis Youth & Community Center during your travels to Hyannis. Stroll along the beautiful beaches or visit the shops in the area.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248635976357139)

[](https://www.expedia.ca/Zion-Union-Heritage-Museum-Hotels.0-l724958852913086464-0.Travel-Guide-Filter-Hotels)

### Zion Union Heritage Museum

You can spend an afternoon exploring the galleries in Zion Union Heritage Museum during your travels in Hyannis. Make time to visit the area's shops, or simply enjoy its seafood restaurants.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=724958852913086464)

[](https://www.expedia.ca/Commotion-Charters-Hotels.0-l553248621532666521-0.Travel-Guide-Filter-Hotels)

### Commotion Charters

Enjoy an outing to Commotion Charters during your stay in Hyannis. Attend a sporting event or simply enjoy the seafood restaurants while you're in the area.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532666521)

## Frequently asked questions

### What's the area like around Main Street Hyannis?

> Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, check out the 179 hotels and other accommodations you'll find within a mile.

### What's the best hotel to stay near Main Street Hyannis?

> Adjacent to Main Street Hyannis, [Hyannis Travel Inn](https://www.expedia.ca/Hyannis-Hotels-Hyannis-Travel-Inn.h1379109.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include [Hyannis Harbor Hotel](https://www.expedia.ca/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information) and [Comfort Inn Hyannis - Cape Cod](https://www.expedia.ca/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information).

### How many hotels can I expect to find close to Main Street Hyannis?

> Expedia has 179 hotels and other accommodations within a mile from Main Street Hyannis.

### If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?

> Yes, you'll find most hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view top deals close to Main Street Hyannis.

### What can I see and do near Main Street Hyannis?

> John F. Kennedy Hyannis Museum, Cape Cod Maritime Museum, and Whydah Pirate Museum feature captivating exhibits. Hyannis Harbor, Edward Gorey House, and Sandy Neck Lighthouse are landmarks that you won't want to miss. You can enjoy live performances at Cape Cod Melody Tent and Barnstable Performing Arts Center.

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-   [Hotels near Pirate's Cove Mini Golf](https://www.expedia.ca/Pirates-Cove-Mini-Golf-Hotels.0-l6127099-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Seagull Beach](https://www.expedia.ca/Seagull-Beach-Hotels.0-l6127074-0.Travel-Guide-Filter-Hotels)
-   [South Yarmouth Hotels](https://www.expedia.ca/South-Yarmouth-Hotels.d7627.Travel-Guide-Hotels)
-   [Hotels near Veterans Memorial Park](https://www.expedia.ca/Veterans-Memorial-Park-Hotels.0-l553248621532666520-0.Travel-Guide-Filter-Hotels)
-   [West Yarmouth Hotels](https://www.expedia.ca/West-Yarmouth-Hotels.d10485.Travel-Guide-Hotels)
-   [Hotels near Whydah Pirate Museum](https://www.expedia.ca/Whydah-Pirate-Museum-Hotels.0-l553248621533117085-0.Travel-Guide-Filter-Hotels)
-   [Yarmouth Port Hotels](https://www.expedia.ca/Yarmouth-Port-Hotels.d183353.Travel-Guide-Hotels)

-   [Flights to Hyannis](https://www.expedia.ca/Cheap-Flights-To-Hyannis.d1544.Travel-Guide-Flights)
-   [Flights from Flint to Hyannis](https://www.expedia.ca/lp/flights/1238/1544/flint-to-hyannis)
-   [Flights from Winston-Salem to Hyannis](https://www.expedia.ca/lp/flights/1605/1544/winston-salem-to-hyannis)
-   [Flights from Montreal to Hyannis](https://www.expedia.ca/lp/flights/178288/1544/montreal-to-hyannis)
-   [Flights from Toronto to Hyannis](https://www.expedia.ca/lp/flights/178314/1544/toronto-to-hyannis)
-   [Flights from Acapulco to Hyannis](https://www.expedia.ca/lp/flights/179991/1544/acapulco-to-hyannis)
-   [Flights from Monroe to Hyannis](https://www.expedia.ca/lp/flights/2352/1544/monroe-to-hyannis)
-   [Flights from Saskatoon to Hyannis](https://www.expedia.ca/lp/flights/4117/1544/saskatoon-to-hyannis)
-   [Flights from Scranton to Hyannis](https://www.expedia.ca/lp/flights/6023532/1544/scranton-to-hyannis)
-   [Flights from Buffalo to Hyannis](https://www.expedia.ca/lp/flights/602674/1544/buffalo-to-hyannis)
-   [Flights from Niagara Falls to Hyannis](https://www.expedia.ca/lp/flights/602721/1544/niagara-falls-to-hyannis)
-   [Flights from Sierra Vista to Hyannis](https://www.expedia.ca/lp/flights/6054720/1544/sierra-vista-to-hyannis)
-   [Flights from Deer Lake - Corner Brook to Hyannis](https://www.expedia.ca/lp/flights/6057678/1544/deer-lake-corner-brook-to-hyannis)
-   [Flights from Latham to Hyannis](https://www.expedia.ca/lp/flights/9553/1544/latham-to-hyannis)

-   [Hyannis Vacations](https://www.expedia.ca/Hyannis.d1544.Destination-Travel-Guides)
-   [Visit Hyannis](https://www.expedia.ca/Hyannis.dx1544)
-   [John F. Kennedy Hyannis Museum](https://www.expedia.ca/John-F-Kennedy-Hyannis-Museum-Hyannis.d6070185.Vacation-Attraction)

-   [Avis Rental Cars in Hyannis](https://www.expedia.ca/Avis-Car-Rentals-In-Hyannis.d1544-c41.Car-Rental-Guide-Suppliers)
-   [Budget Rental Cars in Hyannis](https://www.expedia.ca/Budget-Car-Rentals-In-Hyannis.d1544-c39.Car-Rental-Guide-Suppliers)
-   [Car rental Hyannis](https://www.expedia.ca/Car-Rentals-In-Hyannis.d1544.Car-Rental-Guide)
-   [Dollar Rent A Car Rental Cars in Hyannis](https://www.expedia.ca/Dollar-Rent-A-Car-Car-Rentals-In-Hyannis.d1544-c43.Car-Rental-Guide-Suppliers)
-   [Enterprise Rental Cars in Hyannis](https://www.expedia.ca/Enterprise-Car-Rentals-In-Hyannis.d1544-c15.Car-Rental-Guide-Suppliers)
-   [Full-Size Car Rentals in Hyannis](https://www.expedia.ca/Fullsize-Car-Rentals-In-Hyannis.d1544-tFullsize.Car-Rental-Guide-Class)
-   [Hertz Rental Cars in Hyannis](https://www.expedia.ca/Hertz-Car-Rentals-In-Hyannis.d1544-c40.Car-Rental-Guide-Suppliers)
-   [National Car Rental Rental Cars in Hyannis](https://www.expedia.ca/National-Car-Rental-Car-Rentals-In-Hyannis.d1544-c42.Car-Rental-Guide-Suppliers)
-   [Payless Rental Cars in Hyannis](https://www.expedia.ca/Payless-Car-Rentals-In-Hyannis.d1544-c38.Car-Rental-Guide-Suppliers)
-   [Rent A Wreck Rental Cars in Hyannis](https://www.expedia.ca/Rent-A-Wreck-Car-Rentals-In-Hyannis.d1544-c33.Car-Rental-Guide-Suppliers)
-   [Sixt Rental Cars in Hyannis](https://www.expedia.ca/Sixt-Car-Rentals-In-Hyannis.d1544-c35.Car-Rental-Guide-Suppliers)

-   [Hyannis Vacation Rentals](https://www.expedia.ca/Hyannis-Vacation-Rentals.d1544.Travel-Guide-VacationRentals)

-   [Things to do in Hyannis](https://www.expedia.ca/Things-To-Do-In-Hyannis.d1544.Travel-Guide-Activities)