Title: Best Hotels Near Main Street Hyannis, Hyannis from CA $94 | Expedia.ca [Hyannis Travel Guide](https://expedia.ca/Hyannis.dx1544)[Vacation Rentals in Hyannis](https://expedia.ca/Hyannis-Vacation-Rentals.d1544.Travel-Guide-VacationRentals)[Flights to Hyannis](https://expedia.ca/Cheap-Flights-To-Hyannis.d1544.Travel-Guide-Flights)[Things to do in Hyannis](https://expedia.ca/Things-To-Do-In-Hyannis.d1544.Travel-Guide-Activities)[Main Street Hyannis Car Rentals](https://expedia.ca/Car-Rentals-In-Main-Street-Hyannis.d6287458.Car-Rental-Guide)[Main Street Hyannis Vacations](https://expedia.ca/Main-Street-Hyannis-Hyannis.d6287458.Vacation-Attraction) ![Main Street Hyannis featuring street scenes as well as a couple](https://images.trvl-media.com/place/6287458/f083813a-eac6-4b18-a763-a901fa1ed4e5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near Main Street Hyannis, Hyannis from CA $94 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 10 - Dec 11](https://www.expedia.ca/Hotel-Search?regionId=6287458&startDate=2025-12-10&endDate=2025-12-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 11 - Dec 12](https://www.expedia.ca/Hotel-Search?regionId=6287458&startDate=2025-12-11&endDate=2025-12-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6287458&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6287458&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Main Street Hyannis hotels ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/7438dff7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/6d244f7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/0c3650ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 2 Queen Beds, Harbour View | Living area](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/c85afb09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Anchor In Distinctive Waterfront Lodging [](https://www.expedia.ca/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information) 0.6 km from Main Street Hyannis 9.4/10 Exceptional (1003) "Beautiful quaint hotel, with a nice view of the water. The place has a pool, a fire pit and nice spacious rooms. Would stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberto CA $193 CA $261 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/76dbfadf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/10f6fac9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![VISIONARY KING ELITE](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/82541975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/75730e05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Uncommoner Hotel by Reverie Boutique Collection [](https://www.expedia.ca/West-Yarmouth-Hotels-Tidewater-Inn.h480770.Hotel-Information) 1.9 km from Main Street Hyannis 9.4/10 Exceptional (97) "Hotel was quiet and very clean , pool water was cool" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robyn CA $147 CA $168 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/West-Yarmouth-Hotels-Tidewater-Inn.h480770.Hotel-Information) ![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/85f07916.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/557f1a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, 2 poolside bars](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/37259fda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/a80381e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bayside Resort Hotel [](https://www.expedia.ca/West-Yarmouth-Hotels-Bayside-Resort-Hotel.h896697.Hotel-Information) 2.3 km from Main Street Hyannis 8.8/10 Excellent (1520) "excellent quality of food. Pool and hot tub fabulous" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah CA $125 CA $159 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/West-Yarmouth-Hotels-Bayside-Resort-Hotel.h896697.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/a974137b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/8c1d510e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/dd4b8ad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/9db04da3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Cod Hyannis [](https://www.expedia.ca/Hyannis-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Cod-Hyannis.h7660.Hotel-Information) 2.3 km from Main Street Hyannis 8.8/10 Excellent (656) "Great people, nice breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lorri CA $140 CA $160 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Hyannis-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Cod-Hyannis.h7660.Hotel-Information) ![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/dc2c7156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Non Smoking | Living area](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/667d7c08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/f33d73c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/f6ec329c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Cape Cod-West Yarmouth [](https://www.expedia.ca/West-Yarmouth-Hotels-Hampton-Inn-Suites-Cape-Cod-West-Yarmouth.h2558618.Hotel-Information) 1.7 km from Main Street Hyannis 8.8/10 Excellent (1000) "Excellent stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $143 CA $164 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/West-Yarmouth-Hotels-Hampton-Inn-Suites-Cape-Cod-West-Yarmouth.h2558618.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/ba128f08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/b801373a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/3168dc41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/1a19fbd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard By Marriott Cape Cod Hyannis [](https://www.expedia.ca/Hyannis-Hotels-Courtyard-By-Marriott-Cape-Cod-Hyannis.h1517.Hotel-Information) 1.7 km from Main Street Hyannis 8.8/10 Excellent (486) "Pretty nice location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Saulius CA $169 CA $194 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Hyannis-Hotels-Courtyard-By-Marriott-Cape-Cod-Hyannis.h1517.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/9f940314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/2de66a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/ce103da5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two Double Beds](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/85ee8ddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doubletree by Hilton Cape Cod - Hyannis [](https://www.expedia.ca/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information) 1 km from Main Street Hyannis 8.4/10 Very good (877) "Nice room, freindly staff. The downside is the food was pricey. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steffanie CA $158 CA $181 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/f7a87ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/b13a9f06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/d4c5b048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/0231de53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Hyannis - Cape Cod [](https://www.expedia.ca/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information) 0.3 km from Main Street Hyannis 8.0/10 Very good (1000) "Well appointed lodging with very friendly and attentive staff. Perfect central location with easy walk to many local sights as well as convenient access to ferry terminal. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kerri CA $136 CA $155 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/5d7ebe6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/9d421872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/e4d68938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/e9405833.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Resort [](https://www.expedia.ca/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information) 0.3 km from Main Street Hyannis 8.2/10 Very good (43) "Room was very clean. Staff were courteous!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy CA $151 CA $173 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/aa954682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/efa49ff6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/6cc9c6b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/3bffd99c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cape Sands Inn [](https://www.expedia.ca/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information) 1.9 km from Main Street Hyannis 8.2/10 Very good (1013) "I love this hotel clean good up keep " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerome CA $82 CA $94 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/741b5772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/0271fbcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/b017dd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/3225f1fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyannis Harbor Hotel [](https://www.expedia.ca/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information) 0.6 km from Main Street Hyannis 8.0/10 Very good (1003) "Amazing place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mounir CA $161 CA $241 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/6128ed99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/5c644d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/99f74591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/c18bcef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Hyannis by IHG [](https://www.expedia.ca/Hyannis-Hotels-Holiday-Inn-Hyannis-By-IHG.h12477.Hotel-Information) 2.9 km from Main Street Hyannis 8.2/10 Very good (976) "Check in was easy and the front desk person was wonderful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anastasios CA $148 CA $170 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Hyannis-Hotels-Holiday-Inn-Hyannis-By-IHG.h12477.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/f7fc1d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/ef69e045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/9afdfb4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/786ccd3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyannis Plaza Hotel [](https://www.expedia.ca/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information) 0.9 km from Main Street Hyannis 7.0/10 Good (966) "good stay for night" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $90 CA $117 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information) ![Family House, Private Bathroom, Pool View | Shared kitchen](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/1de4e978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Private Bathroom, Pool View | Restaurant](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/6936f2b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Private Bathroom, Pool View](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/fa76fd07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Private Bathroom, Pool View | Shared kitchen](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/4a3b4c38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sal's Place [](https://www.expedia.ca/Hyannis-Hotels-Sals-Place.h119373964.Hotel-Information) 2.5 km from Main Street Hyannis CA $388 CA $610 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Hyannis-Hotels-Sals-Place.h119373964.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/37000000/36050000/36043300/36043240/79d06d8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/37000000/36050000/36043300/36043240/8cac69f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/37000000/36050000/36043300/36043240/3c6038a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily cooked-to-order breakfast](https://images.trvl-media.com/lodging/37000000/36050000/36043300/36043240/2136ce97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn on Main [](https://www.expedia.ca/Yarmouth-Port-Hotels-Inn-On-Main.h36043240.Hotel-Information) 6.4 km from Main Street Hyannis 10/10 Exceptional (73) "We love staying here! Best dog B&B in America!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara CA $378 CA $432 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Yarmouth-Port-Hotels-Inn-On-Main.h36043240.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b57e0b1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/389ef6aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/e05c3d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b82acf26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Resort Cape Cod [](https://www.expedia.ca/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) 3.3 km from Main Street Hyannis 8.8/10 Excellent (412) "The entire place was spotless and rooom beet pleasant. Staff was super friendly and the Landshark Bar was excellent. Highly recommend a stay here ! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen CA $194 CA $301 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/7000000/6700000/6697800/6697712/32aabc06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Cottage, 2 Bedrooms, Garden View | Private kitchen](https://images.trvl-media.com/lodging/7000000/6700000/6697800/6697712/d5121e24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/7000000/6700000/6697800/6697712/b61b6541.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6700000/6697800/6697712/9440495d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Escape Inn [](https://www.expedia.ca/South-Yarmouth-Hotels-The-Escape-Inn.h6697712.Hotel-Information) 7.6 km from Main Street Hyannis 9.4/10 Exceptional (653) "One of the best hotels I stayed at " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $124 CA $142 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/South-Yarmouth-Hotels-The-Escape-Inn.h6697712.Hotel-Information) ![Deluxe Suite, Oceanfront, 2 Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/1000000/800000/792100/792097/369d6210.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/792100/792097/e7706171.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio, Oceanfront, 1 Bedroom | Terrace/patio](https://images.trvl-media.com/lodging/1000000/800000/792100/792097/adb3fb01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/800000/792100/792097/65a756bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ocean Club on Smuggler's Beach [](https://www.expedia.ca/South-Yarmouth-Hotels-Ocean-Club-On-Smugglers-Beach.h792097.Hotel-Information) 6.9 km from Main Street Hyannis 9.2/10 Wonderful (1000) "The Ocean Club is always a great place to stay. Very convenient location and a great place for a walk on the beach. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve CA $206 CA $251 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/South-Yarmouth-Hotels-Ocean-Club-On-Smugglers-Beach.h792097.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/39000000/38360000/38357900/38357891/03e2a40a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/39000000/38360000/38357900/38357891/703e14aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/39000000/38360000/38357900/38357891/bc79e1a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/39000000/38360000/38357900/38357891/acdc0987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aiden by Best Western Cape Cod - West Yarmouth [](https://www.expedia.ca/West-Yarmouth-Hotels-Aiden-By-Best-Western-Cape-Point.h38357891.Hotel-Information) 3.7 km from Main Street Hyannis 8.0/10 Very good (1001) "Nice place and good options for breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer CA $134 CA $154 total includes taxes & fees Dec 18 - Dec 19 [](https://www.expedia.ca/West-Yarmouth-Hotels-Aiden-By-Best-Western-Cape-Point.h38357891.Hotel-Information) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1150000/1143500/1143483/dbe1f5fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1150000/1143500/1143483/c39a524d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's play area - outdoor](https://images.trvl-media.com/lodging/2000000/1150000/1143500/1143483/2726cfb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1150000/1143500/1143483/442db5c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mariner Resort Cape Cod by The Red Collection [](https://www.expedia.ca/West-Yarmouth-Hotels-The-Mariner-Resort.h1143483.Hotel-Information) 4.3 km from Main Street Hyannis 8.0/10 Very good (432) "Great proximity to quick shopping and restaurants/coffee" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theodore CA $109 CA $138 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/West-Yarmouth-Hotels-The-Mariner-Resort.h1143483.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-24&endDate=2025-12-25®ionId=6287458&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Main Street Hyannis Hotel Reviews ![Courtyard Resort](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/5d7ebe6e_y.jpg) ### Courtyard Resort 10/10 Excellent "Room was very clean. Staff were courteous!" [](https://expedia.ca/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information) ![Doubletree by Hilton Cape Cod - Hyannis](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/9f940314_y.jpg) ### Doubletree by Hilton Cape Cod - Hyannis 10/10 Excellent "Everything was great . One comforter on the bed was a little dirty. We liked everything else." [](https://expedia.ca/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information) ![Hyannis Travel Inn](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/fe11d49f_y.jpg) ### Hyannis Travel Inn 10/10 Excellent "Very kind staff. Functional, clean room. Had an early bus and they let me take a few things for breakfast the night before." [](https://expedia.ca/Hyannis-Hotels-Hyannis-Travel-Inn.h1379109.Hotel-Information) ![Hyannis Harbor Hotel](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/741b5772_y.jpg) ### Hyannis Harbor Hotel 10/10 Excellent "Perfect hotel" [](https://expedia.ca/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information) ![Anchor In Distinctive Waterfront Lodging](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/7438dff7_y.jpg) ### Anchor In Distinctive Waterfront Lodging 10/10 Excellent "I believe Sandi at the desk gave me the best greeting and welcome I have ever received from a hotel. She wasn't 'corporate' but very personable. She didn't just tell us about the breakfast, the pool, etc...she took us in a small tour to show us. The room where we had breakfast was very homey with a roaring fire in the fireplace. " [](https://expedia.ca/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information) ![Margaritaville Resort Cape Cod](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b57e0b1f_y.jpg) ### Margaritaville Resort Cape Cod 10/10 Excellent "The entire place was spotless and rooom beet pleasant. Staff was super friendly and the Landshark Bar was excellent. Highly recommend a stay here ! " [](https://expedia.ca/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) ![Bayside Resort Hotel](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/85f07916_y.jpg) ### Bayside Resort Hotel 10/10 Excellent "Nice and clean, friendly receptionist. Pool is great, amusement arcade good for kids. Reasonable rates and location on the main road through West Yarmouth. Nicely lit up for Christmas. Back area looks on to lagoon and has a fire pit and sand" [](https://expedia.ca/West-Yarmouth-Hotels-Bayside-Resort-Hotel.h896697.Hotel-Information) ![Cape Sands Inn](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/aa954682_y.jpg) ### Cape Sands Inn 10/10 Excellent "Clean room, great rate easy checkin and easy checkout. Will stay again. " [](https://expedia.ca/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Cod Hyannis](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/a974137b_y.jpg) ### Fairfield Inn & Suites by Marriott Cape Cod Hyannis 10/10 Excellent "Beautiful hotel great room" [](https://expedia.ca/Hyannis-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Cod-Hyannis.h7660.Hotel-Information) ## Hotels near other Main Street Hyannis attractions ![John F. Kennedy Hyannis Museum showcases bronze statue and historic architecture in Hyannis Massachusetts](https://images.trvl-media.com/place/6070185/b92268d1-27eb-4055-a07b-800040c40061.jpg) ### John F. Kennedy Hyannis Museum 4.4/5 (259 reviews) Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6070185) ![Cape Cod Maritime Museum which includes a bay or harbor and signage](https://images.trvl-media.com/place/553248635146342095/6c8cea24-96a8-41da-86a8-64397b473956.jpg) ### Cape Cod Maritime Museum You can spend an afternoon exploring the galleries in Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the seaside in this family-friendly area, or check out its seafood restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635146342095) ![St. Francis Xavier Church featuring signage and a church or cathedral](https://images.trvl-media.com/place/6286986/d75d0252-a6d7-4bb9-9dd9-82f6c06a49ac.jpg) ### St. Francis Xavier Church 4.4/5 (45 reviews) After visiting St. Francis Xavier Church, make a plan to see the other sights and activities in Hyannis. Wander the beautiful beaches and waterfront in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6286986) ![John F. Kennedy Memorial which includes flowers](https://images.trvl-media.com/place/6286978/9b85082f-75c6-4ae3-ac16-7a3f1c71a2a9.jpg) ### John F. Kennedy Memorial 4.5/5 (110 reviews) Take a moment to reflect on John F. Kennedy’s defining role in American politics, as well as his untimely death, at this poignant memorial. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6286978) ### Hyannis Armory Learn about the local history of Hyannis when you take a trip to Hyannis Armory. Wander the waterfront and beautiful beaches in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=950930054190297088) ### Hyannis Youth & Community Center You can take time to visit Hyannis Youth & Community Center during your travels to Hyannis. Stroll along the beautiful beaches or visit the shops in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635976357139) ### Zion Union Heritage Museum You can spend an afternoon exploring the galleries in Zion Union Heritage Museum during your travels in Hyannis. Make time to visit the area's shops, or simply enjoy its seafood restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=724958852913086464) ### Commotion Charters Enjoy an outing to Commotion Charters during your stay in Hyannis. Attend a sporting event or simply enjoy the seafood restaurants while you're in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532666521) ## Frequently asked questions ### What's the area like around Main Street Hyannis? ### What's the best hotel to stay near Main Street Hyannis? ### How many hotels can I expect to find close to Main Street Hyannis? ### If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund? ### What can I see and do near Main Street Hyannis? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [4 Star Hotels in Hyannis ](https://www.expedia.ca/4Star-Hyannis-Hotels.s40-0-d1544.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Hyannis ](https://www.expedia.ca/5Star-Hyannis-Hotels.s50-0-d1544.Travel-Guide-Filter-Hotels) - [B&B in Barnstable County ](https://www.expedia.ca/Barnstable-County-Bed-And-Breakfast.d553248635976434260-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Barnstable Hotels ](https://www.expedia.ca/Barnstable-Hotels.d9658.Travel-Guide-Hotels) - 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