Title: Lower Matecumbe Key Vacation Rentals from CA $305: Short-Term Rentals for 2026 | Expedia.ca

[Lower Matecumbe Key Travel Guide](https://expedia.ca/Lower-Matecumbe-Key.dx553248635975749077)[Hotels in Lower Matecumbe Key](https://expedia.ca/Lower-Matecumbe-Key-Hotels.d553248635975749077.Travel-Guide-Hotels)[Flights to Lower Matecumbe Key](https://expedia.ca/Cheap-Flights-To-Lower-Matecumbe-Key.d553248635975749077.Travel-Guide-Flights)[Lower Matecumbe Key Car Rentals](https://expedia.ca/Car-Rentals-In-Lower-Matecumbe-Key.d553248635975749077.Car-Rental-Guide)[Lower Matecumbe Key Vacation Packages](https://expedia.ca/Lower-Matecumbe-Key.d553248635975749077.Destination-Travel-Guides)

![Anne\'s Beach featuring general coastal views](https://images.trvl-media.com/place/6282204/470955d9-2a40-4717-96b3-ce871a5e0499.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Lower Matecumbe Key Vacation Rentals

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## Check prices for these dates

In two weeks

[Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248635975749077&startDate=2026-01-09&endDate=2026-01-11&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=553248635975749077&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=553248635975749077&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=553248635975749077&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Find vacation rentals that suit your style

Aparthotels

[](https://www.expedia.ca/Hotel-Search?destination=Lower+Matecumbe+Key%2C+Florida%2C+United+States+of+America&regionId=553248635975749077&latLong=24.86528%2C-80.714508&adults=2&startDate=2026-03-22&d1=2026-03-22&endDate=2026-03-25&d2=2026-03-25&lodging=APART_HOTEL)

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Lower+Matecumbe+Key%2C+Florida%2C+United+States+of+America&regionId=553248635975749077&latLong=24.86528%2C-80.714508&adults=2&startDate=2026-03-22&d1=2026-03-22&endDate=2026-03-25&d2=2026-03-25&lodging=APARTMENT)

Villas

[](https://www.expedia.ca/Hotel-Search?destination=Lower+Matecumbe+Key%2C+Florida%2C+United+States+of+America&regionId=553248635975749077&latLong=24.86528%2C-80.714508&adults=2&startDate=2026-03-22&d1=2026-03-22&endDate=2026-03-25&d2=2026-03-25&lodging=VILLA)

Condos

[](https://www.expedia.ca/Hotel-Search?destination=Lower+Matecumbe+Key%2C+Florida%2C+United+States+of+America&regionId=553248635975749077&latLong=24.86528%2C-80.714508&adults=2&startDate=2026-03-22&d1=2026-03-22&endDate=2026-03-25&d2=2026-03-25&lodging=CONDO)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Lower+Matecumbe+Key%2C+Florida%2C+United+States+of+America&regionId=553248635975749077&latLong=24.86528%2C-80.714508&adults=2&startDate=2026-03-22&d1=2026-03-22&endDate=2026-03-25&d2=2026-03-25&lodging=VACATION_HOME)

Cottages

[](https://www.expedia.ca/Hotel-Search?destination=Lower+Matecumbe+Key%2C+Florida%2C+United+States+of+America&regionId=553248635975749077&latLong=24.86528%2C-80.714508&adults=2&startDate=2026-03-22&d1=2026-03-22&endDate=2026-03-25&d2=2026-03-25&lodging=COTTAGE)

Houseboats

[](https://www.expedia.ca/Hotel-Search?destination=Lower+Matecumbe+Key%2C+Florida%2C+United+States+of+America&regionId=553248635975749077&latLong=24.86528%2C-80.714508&adults=2&startDate=2026-03-22&d1=2026-03-22&endDate=2026-03-25&d2=2026-03-25&lodging=HOUSE_BOAT)

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## Top Lower Matecumbe Key Hotel Reviews

![Cheeca Lodge & Spa](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723_y.jpg)

### Cheeca Lodge & Spa

10/10 Excellent

"Fabulous waterfront, activities, and dining as well as the staff. "

[](https://expedia.ca/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information)

![Drift Hotel](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209518/f3e504e7_y.jpg)

### Drift Hotel

10/10 Excellent

"Beautifully kept grounds and rooms. Very friendly and helpful staff. Peaceful location. Would recommend."

[](https://expedia.ca/Key-Largo-Hotels-Drift-Hotel.h13209518.Hotel-Information)

![Creekside Inn](https://images.trvl-media.com/lodging/2000000/1580000/1576800/1576773/5e43c05b_y.jpg)

### Creekside Inn

10/10 Excellent

"Goo"

[](https://expedia.ca/Tavernier-Hotels-Creekside-Inn-Islamorada.h1576773.Hotel-Information)

![Chesapeake Beach Resort](https://images.trvl-media.com/lodging/1000000/10000/4200/4170/689f4306_y.jpg)

### Chesapeake Beach Resort

10/10 Excellent

"The breakfasts are great "

[](https://expedia.ca/Islamorada-Hotels-Chesapeake-Beach-Resort.h4170.Hotel-Information)

![Baker's Cay Resort Key Largo, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/20000/14100/14042/bbdba544_y.jpg)

### Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent

"Very good "

[](https://expedia.ca/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information)

![Coconut Cove Resort and Marina](https://images.trvl-media.com/lodging/5000000/4190000/4182600/4182524/667446d9_y.jpg)

### Coconut Cove Resort and Marina

10/10 Excellent

"While the facility has some age on it, everything was very clean and well kept."

[](https://expedia.ca/Islamorada-Hotels-Coconut-Cove-Resort-And-Marina.h4182524.Hotel-Information)

![Islander Resort](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/5adae4af_y.jpg)

### Islander Resort

10/10 Excellent

"The resort was perfect Everyone from checking in and during our stay could not have been nicer and helpful"

[](https://expedia.ca/Islamorada-Hotels-Islander-Resort.h475438.Hotel-Information)

![Amara Cay Resort](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/84b50729_y.jpg)

### Amara Cay Resort

10/10 Excellent

"I would give this hotel one the highest ratings for my most recent stays in the area. The views were spectacular. All of the staff were very friendly and helpful. Very very minor thing was the condition of the furniture and electrical sockets weren't the best quality but I just loved everything else so much that it would not deter me from returning."

[](https://expedia.ca/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information)

![Hawks Cay Resort](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/b1845555_y.jpg)

### Hawks Cay Resort

10/10 Excellent

"Outstanding in every wat"

[](https://expedia.ca/Marathon-Hotels-Hawks-Cay-Resort.h6068.Hotel-Information)

## Find out more about Lower Matecumbe Key

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Lower Matecumbe Key. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

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