Photo by Michael Schuier

Search Ladys Island Villa Rentals from CA $127

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Find vacation rentals that suit your style

apart-hotel image
Aparthotels
Aparthotels
Apartment image
Apartments
Apartments

Check prices for these dates

Next weekend
Nov 20 - Nov 22
In two weeks
Nov 27 - Nov 29
In one month
Dec 11 - Dec 13
In two months
Jan 8 - Jan 10

Our top choices for Ladys Island villas

A wide sandy beach with gentle waves and a clear blue sky.

1. Relax & Regroup at the Beach- HUGE Fall discounts! Check us out!

Relax & Regroup at the Beach- HUGE Fall discounts! Check us out!
Fripp Island
9.8 out of 10, Exceptional, (118 reviews)
"Perfect spot for a quiet getaway. We loved our stay!"
United States
Jennifer M.
The price is CA $198
CA $575 total
includes taxes & fees
Nov 29 - Nov 30
Relax & Regroup at the Beach- HUGE Fall discounts! Check us out!
A coastal view with a pathway leading to the beach, surrounded by trees and greenery.

2. Tranquility by the Beach 1st Fl Sleeps 6,King Bed

Tranquility by the Beach 1st Fl Sleeps 6,King Bed
Mid Island
9.0 out of 10, Wonderful, (70 reviews)
"We enjoyed the place, checkin in & out was easy, nice short walk to the beach. We loved our stay on HHI"
United States
Thomas G.
The price is CA $141
CA $391 total
includes taxes & fees
Nov 16 - Nov 17
Tranquility by the Beach 1st Fl Sleeps 6,King Bed
A pool area with lounge chairs and a covered seating area, surrounded by palm trees and a building with a balcony.

3. Captain John Fripp Villa Pool side and Ocean View

Captain John Fripp Villa Pool side and Ocean View
Fripp Island
10.0 out of 10, Exceptional, (36 reviews)
"Super clean and the best stocked kitchen we have ever seen. Overall awesome place and we hope to return."
United States
Nick N.
The price is CA $284
CA $881 total
includes taxes & fees
Nov 22 - Nov 23
Captain John Fripp Villa Pool side and Ocean View
A wooden balcony with two green chairs and a view of a residential area with trees and parked cars.

4. Tranquility in Paradise- 2bdr pet-friendly villa w/parking

Tranquility in Paradise- 2bdr pet-friendly villa w/parking
Mid Island
9.6 out of 10, Exceptional, (5 reviews)
"Very good stay"
United States
Ellen W.
The price is CA $231
CA $532 total
includes taxes & fees
Nov 16 - Nov 17
Tranquility in Paradise- 2bdr pet-friendly villa w/parking
A balcony with a red chair and a small round table, a concrete wall, and a door leading to another room.

5. Serenity in Paradise

Serenity in Paradise
Mid Island
9.2 out of 10, Wonderful, (10 reviews)
"Awesome place to stay! We would love to come back!"
United States
Katelynn J.
The price is CA $218
CA $516 total
includes taxes & fees
Nov 25 - Nov 26
Serenity in Paradise
A two-story building with a stone facade, multiple windows, and a central entrance with an archway.

6. Newly Renovated Cozy/Modern Pet-Friendly Villa for the entire family to enjoy.

Newly Renovated Cozy/Modern Pet-Friendly Villa for the entire family to enjoy.
Mid Island
8.6 out of 10, Excellent, (7 reviews)
"We enjoyed our stay!! Starbucks right around the corner:), close bike ride to the beach and so much more"
United States
Olga M.
The price is CA $212
CA $509 total
includes taxes & fees
Nov 17 - Nov 18
Newly Renovated Cozy/Modern Pet-Friendly Villa for the entire family to enjoy.
A house with a green door, a small window, and a welcome mat.

7. Elegant and comfortable 2 bedroom pet-friendly villa w/ 2 parking spaces

Elegant and comfortable 2 bedroom pet-friendly villa w/ 2 parking spaces
Mid Island
9.2 out of 10, Wonderful, (7 reviews)
"Everything was absolutely awesome we will be back Thank you so much"
United States
Nakeida Y.
The price is CA $225
CA $525 total
includes taxes & fees
Nov 25 - Nov 26
Elegant and comfortable 2 bedroom pet-friendly villa w/ 2 parking spaces
A tennis court with a wooden railing and a bench.

8. Oceanside Resort! King Master Suite, Sleeps 6, Walk to the Beach!

Oceanside Resort! King Master Suite, Sleeps 6, Walk to the Beach!
Mid Island
10.0 out of 10, Exceptional, (62 reviews)
"We’ve stayed at this resort several times but this was the best stay we’ve had so far!"
United States
Jennifer V.
The price is CA $154
CA $509 total
includes taxes & fees
Nov 19 - Nov 20
Oceanside Resort! King Master Suite, Sleeps 6, Walk to the Beach!
A beachside restaurant with outdoor seating, red umbrellas, and a view of the ocean.

9. TWO Minute Walk to the Beach-Family Friendly Oceanside Resort-King Bed

TWO Minute Walk to the Beach-Family Friendly Oceanside Resort-King Bed
Mid Island
9.6 out of 10, Exceptional, (4 reviews)
"Cozy space close to the beach. Good food nearby and fun drinks by the pool or beach. A wonderful place to relax."
United States
Lyndon R.
The price is CA $127
CA $433 total
includes taxes & fees
Nov 16 - Nov 17
TWO Minute Walk to the Beach-Family Friendly Oceanside Resort-King Bed
A ceiling with string lights, a window with blinds, and a wicker chair.

10. Experience Luxury at the Beach! Oceanside Resort! Huge Oceanside Pool!

Experience Luxury at the Beach! Oceanside Resort! Huge Oceanside Pool!
Mid Island
10.0 out of 10, Exceptional, (158 reviews)
"Place was amazing! Highly recommend for anyone wanting to come down to HH for the weekend "
United States
Alexander A.
The price is CA $141
CA $491 total
includes taxes & fees
Nov 16 - Nov 17
Experience Luxury at the Beach! Oceanside Resort! Huge Oceanside Pool!
A covered porch with a checkered wooden floor, a black chair, and a view of a landscaped garden with trees and shrubs.

11. Modern Island Serenity!

Modern Island Serenity!
Mid Island
9.8 out of 10, Exceptional, (8 reviews)
"Room was great and host was very attentive "
United States
Todd E.
The price is CA $385
CA $801 total
includes taxes & fees
Nov 17 - Nov 18
Modern Island Serenity!
A balcony with a table and two chairs, overlooking a parking area and buildings.

12. Remodeled 1BR Direct Oceanfront- First Floor- Tennis & Pickleball HHB&T A124

Remodeled 1BR Direct Oceanfront- First Floor- Tennis & Pickleball HHB&T A124
Mid Island
10.0 out of 10, Exceptional, (2 reviews)
"Excellent unit with awesome view. Kitchen so well equipped. Comfortable beds. Host is outstanding and responds quickly to any questions we had. Would definitely book this unit again."
United States
Debra H.
The price is CA $221
CA $564 total
includes taxes & fees
Nov 16 - Nov 17
Remodeled 1BR Direct Oceanfront- First Floor- Tennis & Pickleball HHB&T A124
A pool area with lounge chairs and palm trees.

13. OCEAN VIEW - TOP FLOOR

OCEAN VIEW - TOP FLOOR
Mid Island
8.8 out of 10, Excellent, (126 reviews)
"Wonderful place to stay. We would stay there again"
United States
Connie W.
The price is CA $161
CA $371 total
includes taxes & fees
Nov 16 - Nov 17
OCEAN VIEW - TOP FLOOR
A swimming pool with a fence in the foreground, a building with arched doorways in the background, and trees surrounding the area.

14. Beautiful, Cozy 2022 Renovated Villa is a perfect place for a family vacation.

Beautiful, Cozy 2022 Renovated Villa is a perfect place for a family vacation.
Mid Island
8.0 out of 10, Very good, (25 reviews)
"Clean, quiet place that was perfect for our group for one night."
United States
Tim B.
The price is CA $257
CA $648 total
includes taxes & fees
Nov 16 - Nov 17
Beautiful, Cozy 2022 Renovated Villa is a perfect place for a family vacation.
A balcony with a view of the ocean, a round table, two chairs, and a sofa with a patterned pillow.

15. Luxury Direct Oceanview King Villa • Steps to Beach • Gourmet Kitchen

Luxury Direct Oceanview King Villa • Steps to Beach • Gourmet Kitchen
Mid Island
10.0 out of 10, Exceptional, (6 reviews)
"Very beautifully appointed unit. It was a wonderful trip with relaxation a great food. Owner was easy and a joy to work with!!!!"
United States
Blaise B.
The price is CA $238
CA $842 total
includes taxes & fees
Nov 16 - Nov 17
Luxury Direct Oceanview King Villa • Steps to Beach • Gourmet Kitchen
A two-story house with a front porch, a garage, and a landscaped yard with palm trees.

16. Golf Course Views and Grill Deck in Palmetto Dunes

Golf Course Views and Grill Deck in Palmetto Dunes
Mid Island
The price is CA $146
CA $783 total
includes taxes & fees
Nov 17 - Nov 18
Golf Course Views and Grill Deck in Palmetto Dunes
A building with a covered porch, a staircase leading to the entrance, and a sign indicating it is a general store.

17. Inviting Palmetto Dunes condo w/ pool, private W/D & deck near beach & golf

Inviting Palmetto Dunes condo w/ pool, private W/D & deck near beach & golf
Mid Island
10.0 out of 10, Exceptional, (158 reviews)
"Great place to stay. Fits our needs perfectly!"
United States
Charles P.
The price is CA $225
CA $575 total
includes taxes & fees
Nov 17 - Nov 18
Inviting Palmetto Dunes condo w/ pool, private W/D & deck near beach & golf
A deck with sun loungers overlooking a coastal landscape.

18. Coastal Calm Couples Paradise + KING Bed+ Bikes-#131

Coastal Calm Couples Paradise + KING Bed+ Bikes-#131
South End
10.0 out of 10, Exceptional, (19 reviews)
"Fantastic property. Great owners. Perfect location!"
United States
Walker A.
The price is CA $171
CA $469 total
includes taxes & fees
Nov 17 - Nov 18
Coastal Calm Couples Paradise + KING Bed+ Bikes-#131
A hotel with multiple floors, a swimming pool, and a beach area with umbrellas.

19. Oceanside Resort- 5 Min Walk to Beach-2 Bed 2 Bath-Beach Chairs&Wagon-1st Floor

Oceanside Resort- 5 Min Walk to Beach-2 Bed 2 Bath-Beach Chairs&Wagon-1st Floor
Mid Island
9.8 out of 10, Exceptional, (49 reviews)
"Nice, laid back, down to earth resort. Lots of families. Very welcoming."
United States
Alyssa T.
The price is CA $244
CA $607 total
includes taxes & fees
Nov 16 - Nov 17
Oceanside Resort- 5 Min Walk to Beach-2 Bed 2 Bath-Beach Chairs&Wagon-1st Floor
A pool area with lounge chairs and a view of the beach.

20. Oceanfront Villa with Pool

Oceanfront Villa with Pool
South End
10.0 out of 10, Exceptional, (3 reviews)
"Beautiful view and great hosts! Will be back soon!!"
United States
Bridgett D.
Oceanfront Villa with Pool
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Learn more about Ladys Island

Venture to sights like Coosaw Island and Cat Island Driving Range as you discover Ladys Island.

See all hotels in Ladys Island
A sunset over a water body with a wooden fence and trees with Spanish moss.
Photo by Michael Schuier
Open Photo by Michael Schuier

Top reviews in Ladys Island

A modern hotel with a flat roof, large windows, and a well-lit entrance.
SpringHill Suites by Marriott Beaufort

SpringHill Suites by Marriott Beaufort

SpringHill Suites by Marriott Beaufort
Beaufort

10/10 Excellent

Excellent clean quiet great location
Canada
Ashley
Reviewed April 12, 2026
SpringHill Suites by Marriott Beaufort

Frequently Asked Questions

Why book your villa in Ladys Island with Expedia?

Booking a villa in Ladys Island is as simple as deciding on your travel dates and picking a place that suits your style. Searching for something inexpensive or upscale, or a property that also comes with free WiFi? Use Expedia's search filters to narrow your results and find the perfect fit.

How can I find cheap villas in Ladys Island?

An excellent way to score cheap villas in Ladys Island is with Expedia's user-friendly filter tool. Narrow your search results by budget, amenities and star rating to discover unbeatable rates in just a couple of clicks.

Explore a world of travel with Expedia