Guadalupe County Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

Photo by Kate Cadwell

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

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    Plan, book, and manage your trip all in one place

Your Guadalupe County Vacation

Our Guadalupe County vacation packages provide an easy, affordable and immersive way to enjoy all that this unique destination has to offer. If it's nature and culture you're looking for, this is the place to be. Be sure to include Santa Rosa and Vaughn on your list of cities to explore when planning your trip to Guadalupe County. Expedia has flights, hotels and everything else you need to help you organize your own customized Guadalupe County vacation today.

Top vacation destinations in Guadalupe County

Panorama of a severe thunderstorm over the Black Mesa Park at the border of Oklahoma and New Mexico
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Vaughn

Vaughn

Guadalupe County Hotel Deals

La Quinta Inn & Suites by Wyndham Santa Rosa

La Quinta Inn & Suites by Wyndham Santa Rosa

3 out of 5
2277 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
The price is CA $178 per night from May 24 to May 25
CA $178
CA $202 total
May 24 - May 25
includes taxes & fees
9.2/10 Wonderful! (1,500 reviews)
"Clean rooms, helpful staff, pet friendly, good continental breakfast"

Reviewed on May 18, 2026

La Quinta Inn & Suites by Wyndham Santa Rosa
Comfort Inn Santa Rosa on Route 66

Comfort Inn Santa Rosa on Route 66

2.5 out of 5
2524 Historic Route 66 Santa Rosa NM
Fully refundable
The price is CA $135 per night from Jun 15 to Jun 16
CA $135
CA $153 total
Jun 15 - Jun 16
includes taxes & fees
8.4/10 Very Good! (1,010 reviews)
"wifi didnt work. outside door closest to room didnt work."

Reviewed on May 18, 2026

Comfort Inn Santa Rosa on Route 66
Days Inn & Suites by Wyndham Santa Rosa

Days Inn & Suites by Wyndham Santa Rosa

2 out of 5
2255 Historic Route 66 Santa Rosa NM
Fully refundableReserve now, pay when you stay
The price is CA $135 per night from Jun 1 to Jun 2
CA $135
CA $154 total
Jun 1 - Jun 2
includes taxes & fees
8.6/10 Excellent! (641 reviews)
"Clean and user friendly with a good breakfast."

Reviewed on May 19, 2026

Days Inn & Suites by Wyndham Santa Rosa
See all 26 properties in Guadalupe County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does a Guadalupe County vacation package cost?
We make it easy for everyone to travel, with Guadalupe County packages starting from as low as . You'll have the flexibility to combine your favorite airlines, hotels and car rental. For the ultimate escape, why not add a couple of experiences and tours to your travel itinerary?
How do I get a cheap travel package to Guadalupe County?
Track down flights that fit in with your schedule, add a hotel to your booking and watch the savings grow with a Guadalupe County vacation package. It's as easy as that! From flights and hotels to activities and rental cars, Expedia is where your cheap vacation begins. And with over 550 partner airlines and 1,000,000 hotel options all over the world to choose from, you won't be short of choice.
What are the top hotels in Guadalupe County?
If you're headed to Santa Rosa, you can't beat La Quinta Inn & Suites by Wyndham Santa Rosa and Super 8 by Wyndham Santa Rosa. Both are excellent bases for discovering this unique Guadalupe County city.
How far in advance should I book my Guadalupe County vacation?
Reserving your flights early with Expedia means one less thing to have to worry about. Most carriers display prices up to 12 months in advance. This is typically the cheapest time to book. If circumstances have left you booking late, discount tickets to Guadalupe County sometimes become available in the weeks leading up to departure.
What does an Expedia Guadalupe County travel package include?
From hotels and airfares to car rentals, Expedia can help you shape a Guadalupe County package that's ideal for you. Vacationing for a week or longer? Check out a hotel, rental car and flight bundle. If you're taking a quick break, an airfare and hotel deal could suit you better. Experiences can also be added after you've booked. Our packages make it a breeze to save and plan.
What should I know before booking a Guadalupe County travel package?
So many places to wander around, so many things to do. With a package, you can cross more of them off your list. Bundle your flights, rental cars and hotels and score big savings.
Can I choose my airline with a Guadalupe County Expedia vacation package?
Yes, you're in charge. We have access to over 550 partner airlines across the globe, so you can tailor your Guadalupe County adventure according to your travel needs.
If I'm not able to travel, can I cancel my Guadalupe County vacation package?
We understand — life sometimes gets in the way of your plans. If you've locked in a Guadalupe County vacation package and need to change or cancel it, we're here to help. We suggest taking a look at our Customer Service Portal first for information. But generally, if you've taken out your package in the last 24 hours, you may be able to cancel or amend your itinerary at no cost. If it's been more than 24 hours, your airline, hotel or car rental company may impose a charge.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.