Title: Hotels by Independent in Dona Ana from CA $80 | Expedia.ca [Dona Ana Travel Guide](https://expedia.ca/Dona-Ana.dx3000350236)[Hotels in Dona Ana](https://expedia.ca/Dona-Ana-Hotels.d3000350236.Travel-Guide-Hotels)[Vacation Rentals in Dona Ana](https://expedia.ca/Dona-Ana-Vacation-Rentals.d3000350236.Travel-Guide-VacationRentals)[Flights to Dona Ana](https://expedia.ca/Cheap-Flights-To-Dona-Ana.d3000350236.Travel-Guide-Flights)[Dona Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Dona-Ana.d3000350236.Car-Rental-Guide)[Dona Ana Vacation Packages](https://expedia.ca/Dona-Ana.d3000350236.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 12 - Feb 13](https://www.expedia.ca/Hotel-Search?regionId=3000350236&startDate=2026-02-12&endDate=2026-02-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 13 - Feb 14](https://www.expedia.ca/Hotel-Search?regionId=3000350236&startDate=2026-02-13&endDate=2026-02-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=3000350236&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=3000350236&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Dona Ana Independent ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/5b5c1a96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/0464c626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/4108dc14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/0b5e48d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Encanto de Las Cruces [](https://www.expedia.ca/Las-Cruces-Hotels-Hotel-Encanto-De-Las-Cruces.h21267.Hotel-Information) Las Cruces 9.0/10 Wonderful (1,633 reviews) "Loved the service at the bar/restaurant" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sonia CA $151 CA $212 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/Las-Cruces-Hotels-Hotel-Encanto-De-Las-Cruces.h21267.Hotel-Information) ![Full-size fridge, microwave, toaster, cookware/dishes/utensils](https://images.trvl-media.com/lodging/60000000/59870000/59861000/59860905/508a0752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/60000000/59870000/59861000/59860905/e146d19f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | Private kitchen](https://images.trvl-media.com/lodging/60000000/59870000/59861000/59860905/18caa7c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/60000000/59870000/59861000/59860905/2c6cb195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 9 Las Cruces [](https://www.expedia.ca/Las-Cruces-Hotels-Motel-9-Las-Cruces.h59860905.Hotel-Information) Las Cruces 6.4/10 (253 reviews) "Was clean and front desk lady was awesome and beautiful! Real nice I loved the coffee " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Minerva CA $67 CA $80 total includes taxes & fees Feb 24 - Feb 25 [](https://www.expedia.ca/Las-Cruces-Hotels-Motel-9-Las-Cruces.h59860905.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/93000000/92190000/92186700/92186674/0ee34930.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/93000000/92190000/92186700/92186674/d73b3e11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92190000/92186700/92186674/84d1ed9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City Studio, Kitchenette](https://images.trvl-media.com/lodging/93000000/92190000/92186700/92186674/592d9aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Big Chile Inn & Suites [](https://www.expedia.ca/Las-Cruces-Hotels-Big-Chile-Inn-Suites.h92186674.Hotel-Information) Las Cruces 6.8/10 (56 reviews) "Clean, affordable and felt safe " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie CA $77 CA $91 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Las-Cruces-Hotels-Big-Chile-Inn-Suites.h92186674.Hotel-Information) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/114000000/113810000/113801900/113801868/e49a0ed4_edited_6fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/114000000/113810000/113801900/113801868/79a24f19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/114000000/113810000/113801900/113801868/d1e7b649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/114000000/113810000/113801900/113801868/f2b9f370.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Relaxing 3-Bdrs, 2-Baths Spacious Backyard – Family-Friendly & Fully Equipped! [](https://www.expedia.ca/Las-Cruces-Hotels-Relaxing-3-Bdrs.h113801868.Hotel-Information) Las Cruces 10/10 Exceptional (9 reviews) "Very cozy home and the hosts were fantastic and very responsive to messages. We will definitely come back! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa J. [](https://www.expedia.ca/Las-Cruces-Hotels-Relaxing-3-Bdrs.h113801868.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/2e3e8863.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/c1e00df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/93854e6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119460000/119453800/119453789/52479f84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis [](https://www.expedia.ca/Las-Cruces-Hotels-Las-Cruces-Modern-3BR-Near-Downtown.h119453789.Hotel-Information) Las Cruces 9.4/10 Exceptional (13 reviews) "Great location, comfortable set up. I’d stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clay C. CA $144 CA $287 total includes taxes & fees Feb 23 - Feb 24 [](https://www.expedia.ca/Las-Cruces-Hotels-Las-Cruces-Modern-3BR-Near-Downtown.h119453789.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/18000000/17520000/17517100/17517011/1be7158a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17520000/17517100/17517011/9f91d875.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17520000/17517100/17517011/cdc70de0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/18000000/17520000/17517100/17517011/347fddf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Century 21 Motel [](https://www.expedia.ca/Las-Cruces-Hotels-Century-21-Motel.h17517011.Hotel-Information) Las Cruces 6.8/10 (171 reviews) "Loved my stay!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ramon CA $80 CA $103 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Las-Cruces-Hotels-Century-21-Motel.h17517011.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/d537f667.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/9523e9e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/d60d42c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, computer monitors](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/490d7bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yucca House | Views, Jetted Bath, Central Retreat [](https://www.expedia.ca/Las-Cruces-Hotels-Yucca-House-Views.h87796251.Hotel-Information) Las Cruces 9.8/10 Exceptional (36 reviews) "We had a great stay!! Perfect home!! SUPER CLEAN!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bobby L. CA $140 CA $444 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Las-Cruces-Hotels-Yucca-House-Views.h87796251.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112300000/112293600/112293584/498ea670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/113000000/112300000/112293600/112293584/3f402121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112300000/112293600/112293584/1f6cf098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112300000/112293600/112293584/5f78ad71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Desert Whisper 3-bedroom home with Xfinity Cable and WiFi, AC, EV charger [](https://www.expedia.ca/Las-Cruces-Hotels-Desert-Whisper-3-Bedroom-Home-With-WiFi.h112293584.Hotel-Information) Las Cruces 10/10 Exceptional (11 reviews) "Wonderful home! Great neighborhood and very quiet! So clean and relaxing!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Allison K. [](https://www.expedia.ca/Las-Cruces-Hotels-Desert-Whisper-3-Bedroom-Home-With-WiFi.h112293584.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/108000000/107490000/107488900/107488849/122cbe77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107490000/107488900/107488849/9fe70933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/108000000/107490000/107488900/107488849/368dd1a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/108000000/107490000/107488900/107488849/d45d0acb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Josefina's King Suite in Historic Old Mesilla Plaza. [](https://www.expedia.ca/Mesilla-Hotels-Josefinas-King-Suite-In-Historic-Old-Mesilla-Plaza.h107488849.Hotel-Information) Mesilla 10/10 Exceptional (24 reviews) "Excellent location near the square!!! Such a cute cozy place! Loved the fireplace! Highly recommend!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy [](https://www.expedia.ca/Mesilla-Hotels-Josefinas-King-Suite-In-Historic-Old-Mesilla-Plaza.h107488849.Hotel-Information) ![Smart TV, video games, books](https://images.trvl-media.com/lodging/80000000/79720000/79712800/79712757/711f264f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/80000000/79720000/79712800/79712757/bcbd9e9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/80000000/79720000/79712800/79712757/88c26e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/80000000/79720000/79712800/79712757/29c3838a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### "Casa de Maíz" centrally located - close to NMSU [](https://www.expedia.ca/Las-Cruces-Hotels-Casa-De-Maiz-Centrally-Located-Close-To-NMSU.h79712757.Hotel-Information) Las Cruces 10/10 Exceptional (47 reviews) "Excellent place for a family to stay without being cramped in a hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel [](https://www.expedia.ca/Las-Cruces-Hotels-Casa-De-Maiz-Centrally-Located-Close-To-NMSU.h79712757.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-26&endDate=2026-02-27®ionId=3000350236&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDona-Ana-Hotels-Independent.0-0-d3000350236--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDona-Ana-Hotels-Independent.0-0-d3000350236--bIndependent.Travel-Guide-Filter-Hotels) ## Top Dona Ana Hotel Reviews ![Hampton Inn & Suites Las Cruces I-25](https://images.trvl-media.com/lodging/2000000/1670000/1665200/1665185/b0473335_y.jpg) ### Hampton Inn & Suites Las Cruces I-25 10/10 Excellent "The staff was friendly, the breakfast was really good, the rooms were clean. " [](https://expedia.ca/Las-Cruces-Hotels-Hampton-Inn-Suites-Las-Cruces-I-25.h1665185.Hotel-Information) ![Hampton Inn & Suites Las Cruces I-10](https://images.trvl-media.com/lodging/13000000/12820000/12817800/12817768/a6b6426a_y.jpg) ### Hampton Inn & Suites Las Cruces I-10 10/10 Excellent "Large clean room. Friendly staff. Good breakfast included." [](https://expedia.ca/Las-Cruces-Hotels-Hampton-Inn-Suites-Las-Cruces-I-10.h12817768.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain](https://images.trvl-media.com/lodging/1000000/80000/75400/75365/62ae9c45_y.jpg) ### La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain 10/10 Excellent "Very welcoming and clean" [](https://expedia.ca/Las-Cruces-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Las-Cruces-Organ-Mountain.h75365.Hotel-Information) ![Comfort Suites University Las Cruces](https://images.trvl-media.com/lodging/1000000/50000/43200/43179/3f986bbe_y.jpg) ### Comfort Suites University Las Cruces 10/10 Excellent "very happy " [](https://expedia.ca/Las-Cruces-Hotels-Comfort-Suites-University-Las-Cruces.h43179.Hotel-Information) ![Hotel Encanto de Las Cruces](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/5b5c1a96_y.jpg) ### Hotel Encanto de Las Cruces 10/10 Excellent "Loved the service at the bar/restaurant" [](https://expedia.ca/Las-Cruces-Hotels-Hotel-Encanto-De-Las-Cruces.h21267.Hotel-Information) ![Best Western Mission Inn](https://images.trvl-media.com/lodging/1000000/30000/20600/20506/90d9a325_y.jpg) ### Best Western Mission Inn 10/10 Excellent "EVERYTHING WAS PERFECT" [](https://expedia.ca/Las-Cruces-Hotels-Best-Western-Mission-Inn.h20506.Hotel-Information) ![Holiday Inn Express & Suites Las Cruces North by IHG](https://images.trvl-media.com/lodging/5000000/4670000/4663400/4663329/f4f7b494_y.jpg) ### Holiday Inn Express & Suites Las Cruces North by IHG 10/10 Excellent "Arrival/Check-In was smooth and quick. Staff is friendly, courteous and professional. All staff helped us with everything we needed with kind dispositions. The rooms are clean and well stocked. AC/Heating is great (very important to us). The breakfast was simple but, the options were tasty. The coffee available at any time was our favorite! It’s also conveniently located. Close enough to stores when we needed. We will definitely be staying here again. " [](https://expedia.ca/Las-Cruces-Hotels-Holiday-Inn-Express-Suites-Las-Cruces-North.h4663329.Hotel-Information) ![Hilton Garden Inn Las Cruces](https://images.trvl-media.com/lodging/3000000/2880000/2870400/2870330/a3f63928_y.jpg) ### Hilton Garden Inn Las Cruces 10/10 Excellent "Customer service was great, and parking was easy. There’s a convenient restaurant on the grounds. The room was clean, the bed was comfortable, and the sheets were fresh. I didn’t hear much noise from the freeway and slept very well." [](https://expedia.ca/Las-Cruces-Hotels-Hilton-Garden-Inn-Las-Cruces.h2870330.Hotel-Information) ![Staybridge Suites Las Cruces by IHG](https://images.trvl-media.com/lodging/2000000/1410000/1407200/1407181/e6d0a748_y.jpg) ### Staybridge Suites Las Cruces by IHG 10/10 Excellent "Clean room, great staff, good breakfast!" 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