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Santa Cruz Vacation Rentals

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Top Cities in Santa Cruz

A historic cathedral with two prominent towers, surrounded by urban buildings and palm trees.
Vacation RentalsVacation Rentals

Santa Cruz

Santa Cruz

Our top choices for Santa Cruz vacation rentals

A hotel room with a bed, bedside table, and a glass table with a vase of flowers.

1. Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
8.8 out of 10, Excellent, (121 reviews)
"great place to stay!"
United States
Luisa
The price is CA $66
CA $66 total
Nov 15 - Nov 16
Premium Suites Deluxe Aparthotel Equipetrol
A hotel room with a large bed, wooden headboard, bedside lamps, and a bedside phone.

2. Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (107 reviews)
"Great location."
United States
Ruben
The price is CA $33
CA $33 total
Nov 21 - Nov 22
Apart Hotel Premium Suites Santa Cruz
A modern rooftop pool with a city view, wooden flooring, and a seating area.

3. AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (3 reviews)
"Clean room, great staff "
Canada
Peter
The price is CA $39
CA $39 total
Nov 16 - Nov 17
AMERICA APARTMENTS
An outdoor dining area with tables and chairs, surrounded by plants and palm trees.

4. Terranova Suites

Terranova Suites
3.5 star property
Santa Cruz
8.0 out of 10, Very good, (91 reviews)
"Easy to access"
United States
Dorothy
The price is CA $69
CA $69 total
Nov 24 - Nov 25
Terranova Suites
A hotel room with a large bed, a desk with a chair, a TV, and artwork on the wall.

5. Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (13 reviews)
"Perfect hotel"
Turkey
Yener
The price is CA $81
CA $81 total
Dec 15 - Dec 16
Equipetrol Suites Apart Hotel
A series of dome-shaped accommodations with attached wooden decks and hot tubs, surrounded by forested hills.

6. Samaipata Glamping

Samaipata Glamping
3.0 star property
Samaipata
The price is CA $61
CA $61 total
Nov 23 - Nov 24
Samaipata Glamping
A rooftop pool with lounge chairs and a cityscape view at sunset.

7. 58" TV / Swimming Pool / Coworking Space / Fitness Center / Queen-Size Bed

58" TV / Swimming Pool / Coworking Space / Fitness Center / Queen-Size Bed
Equipetrol
8.8 out of 10, Excellent, (3 reviews)
The price is CA $40
CA $70 total
Nov 30 - Dec 1
58" TV / Swimming Pool / Coworking Space / Fitness Center / Queen-Size Bed
A hotel with a pool, lounge chairs, and palm trees.

8. Apart Hotel Toborochi

Apart Hotel Toborochi
3.0 star property
Equipetrol
8.8 out of 10, Excellent, (61 reviews)
"Very comfortable and quiet place and very good location. "
United States
Luis
The price is CA $104
CA $104 total
Nov 15 - Nov 16
Apart Hotel Toborochi
A rooftop swimming pool with a clear view of the city skyline and a partly cloudy sky.

9. Menacho Apartment - Mangales Blue - Norte

Menacho Apartment - Mangales Blue - Norte
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"We arrived at 12:30 am due to our flight and I let the host know of our late arrival time. He had no problem. When checking in I made an error and I couldn’t figure out how to get there. I called the host as late as it was, he answered no problem and was super nice and helpful. He was very communicative although out our stay. Room was fully functional. Had a kitchen with all the necessary utensils, living room area with a tv and a couch that became a bed for our kids. Private master bedroom...
Canada
Evelyn
The price is CA $29
CA $38 total
Nov 29 - Nov 30
Menacho Apartment - Mangales Blue - Norte
A modern kitchen with a black countertop, stainless steel appliances, and a built-in oven.

10. Comfort in the best neighborhood in Santa Cruz—perfect for business travelers and tourists!!

Comfort in the best neighborhood in Santa Cruz—perfect for business travelers and tourists!!
Santa Cruz de la Sierra
The price is CA $36
CA $69 total
Nov 27 - Nov 28
Comfort in the best neighborhood in Santa Cruz—perfect for business travelers and tourists!!
A modern bedroom with a large bed, bedside lamps, and a view into a kitchen area.

11. Aqua: Loft Artistico Urbano

Aqua: Loft Artistico Urbano
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"Excellent atencion todo muy comodo bonito limpio gracias"
United States
Nestor C.
The price is CA $43
CA $86 total
Nov 30 - Dec 1
Aqua: Loft Artistico Urbano
A rooftop pool with clear blue water, surrounded by palm trees and plants, overlooking a cityscape with modern buildings.

12. Apartment with a Balcony & View / Pool / Gym at Equipe

Apartment with a Balcony & View / Pool / Gym at Equipe
Equipetrol
Apartment with a Balcony & View / Pool / Gym at Equipe
A modern building with a glass facade, a pool area with sun loungers, and a clear blue sky.

13. POX: 24th Floor, Green Tower | Luxury and Panoramic Views

POX: 24th Floor, Green Tower | Luxury and Panoramic Views
Santa Cruz de la Sierra
10.0 out of 10, Exceptional, (1 review)
"Very comfortable and nice view and the super clean"
United States
Carlos
The price is CA $107
CA $138 total
Nov 15 - Nov 16
POX: 24th Floor, Green Tower | Luxury and Panoramic Views
A rooftop pool with lounge chairs and a cityscape view at sunset.

14. Apartment with a balcony, pool, fitness center, and coworking space at Equipe

Apartment with a balcony, pool, fitness center, and coworking space at Equipe
Equipetrol
The price is CA $37
CA $67 total
Nov 23 - Nov 24
Apartment with a balcony, pool, fitness center, and coworking space at Equipe
A rooftop terrace with a pool, outdoor seating, and a view of surrounding buildings.

15. A Must-See: Studio Apartment in Sirari-Equipetrol

A Must-See: Studio Apartment in Sirari-Equipetrol
Santa Cruz de la Sierra
The price is CA $32
CA $71 total
Nov 26 - Nov 27
A Must-See: Studio Apartment in Sirari-Equipetrol
A rooftop pool with clear blue water, surrounded by palm trees and a cityscape in the background.

16. Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC

Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC
Equipetrol
The price is CA $36
CA $60 total
Nov 29 - Nov 30
Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC
A modern office space with glass walls, a long table with chairs, and several round ottomans.

17. Enchanting studio with AC in Santa Cruz de la Sierra

Enchanting studio with AC in Santa Cruz de la Sierra
Equipetrol
The price is CA $39
CA $56 total
Nov 15 - Nov 16
Enchanting studio with AC in Santa Cruz de la Sierra
A rooftop pool with clear blue water, surrounded by lounge chairs and potted plants.

18. 1-bedroom apartment, 2 TVs, 2 air conditioners, pool & coworking space

1-bedroom apartment, 2 TVs, 2 air conditioners, pool & coworking space
Equipetrol
The price is CA $40
CA $70 total
Dec 7 - Dec 8
1-bedroom apartment, 2 TVs, 2 air conditioners, pool & coworking space
A rooftop pool with lounge chairs and a cityscape view at sunset.

19. Apartment with a workspace / pool / gym / sleeper sofa

Apartment with a workspace / pool / gym / sleeper sofa
Equipetrol
The price is CA $37
CA $67 total
Nov 30 - Dec 1
Apartment with a workspace / pool / gym / sleeper sofa
Terrace/patio

20. Inspiring Views • Enveloping Comfort

Inspiring Views • Enveloping Comfort
Equipetrol
The price is CA $41
CA $67 total
Nov 23 - Nov 24
Inspiring Views • Enveloping Comfort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

10/10 Excellent
"Amazing staying. The rooms are amazing for the price. The location and view of the city. The staff was very friendly and professional. Totally recommend!"
Erika 1-night trip
Posted 1 day ago
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Cruz vacation rentals we have selected for you start as low as CA $33 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.